108 completed, 16 unknown, 8 active not recruiting, 6 not yet recruiting. 99 Not applicable, 9 Phase 2, 8 Phase 1, 6 Phase 3, 5 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Project SPACE: Testing Daily Text Messages to Reduce Alcohol Use and HIV Risk Behavior CLT- Concrete text messages, CLT- Abstract text messages, Control messages - HIV, Risk Behavior | Not applicable | Not yet recruiting | Emory University | 240 | 2027-02-01 | 2026-08-19 |
| Adapting the ESTEEM Intervention to Improve Mental Health and PrEP Uptake Among Men at Risk of HIV PrEPared Minds/ Mentes PrEParadas - Cognitive Behavioral Therapy, No Intervention - PrEP Use | Not applicable | Not yet recruiting | Wake Forest University Health Sciences | 80 | 2026-10-01 | 2026-09-24 |
| A Single-arm Pilot Feasibility Trial of Healthy Pride lifestyle intervention - Obesity & Overweight | Not applicable | Not yet recruiting | University of Connecticut | 40 | 2026-07-15 | 2026-07-08 |
| Screening for Anal Cancer in Men Who Have Sex With Men Using Pre-Exposure Prophylaxis Anal smear, Self-administered questionnaire, EQ-5D-5L questionnaire - Anal Cancer, Squamous Intraepithelial Lesions | Not applicable | Recruiting | Universitair Ziekenhuis Brussel | 296 | 2025-09-23 | 2026-05-01 |
| Behavioral Intervention for PrEP Service Utilization Among Chinese MSM: A HAPA and CEI Integrated Model HAPA and CEI behavioral intervention, HAPA-based intervention - HIV, PrEP | Not applicable | Not yet recruiting | Peking University | 360 | 2025-07-01 | 2025-06-04 |
| Peer Counselling to Reduce Psychological Distress and Exposure to Violence Among Sexual and Gender Minorities SAATHI intervention (Augmented PM+ counseling), SAATHI intervention with Peer-Led Group Meetings - Mental Health, Psychological Distress | Not applicable | Active not recruiting | Public Health and Environment Research Centre (PERC), Nepal | 960 | 2025-05-20 | 2026-02-18 |
| Cognitive Processing Therapy to Treat PTSD and Sexually Transmitted Infections Among Men Who Have Sex With Men Cognitive Processing Therapy - Stress Disorders, Post-Traumatic, Sexually Transmitted Infection (STI) Prevention | Not applicable | Not yet recruiting | Toronto Metropolitan University | 56 | 2025-03-31 | 2025-02-11 |
| Superiority of On-demand PrEP Versus PEP on Using Doxycycline for Preventing STI in MSM DoxyODPrEP, DoxyPEP - Sexually Transmitted Diseases, Bacterial, Syphilis | Phase 4 | Active not recruiting | Chinese University of Hong Kong | 300 | 2025-03-29 | 2026-06-05 |
| Community Burden of MG Infection Sexually Transmitted Infection (STI), Mycoplasma Genitalium Infection | Recruiting | Chinese University of Hong Kong | 920 | 2025-02-18 | 2025-03-18 | |
| STI Prophylaxis and Emergence of Antimicrobial Resistance Sexually Transmitted Infection (STI) Prevention, Antibiotic Prophylaxis | Recruiting | University College, London | 108 | 2025-02-10 | 2025-03-27 | |
| Filling Gaps in the HIV Pre-exposure Prophylaxis Cascade Through Counseling Counseling, List of resources - Pre-Exposure Prophylaxis (PrEP), Counseling | Not applicable | Not yet recruiting | Unity Health Toronto | 200 | 2025-01-01 | 2024-11-29 |
| P3 Trial: Estimating the Impact of a Multilevel, Multicomponent Intervention to Increase Uptake of HIV Testing and Biomedical HIV Prevention DIY (Do It Yourself), TRUST, SOC - HIV Testing, PrEP Uptake | Not applicable | Recruiting | Columbia University | 480 | 2024-12-19 | 2026-08-31 |
| SmokefreeSGM Español Pilot, Beta Testing a Text-based Smoking Cessation Intervention for Sexual and Gender Minority(SGM) Groups Preferring Spanish Language SmokefreeSGM - Smoking Cessation | Not applicable | Suspended | The University of Texas Health Science Center, Houston | 20 | 2024-08-13 | 2025-07-11 |
| An Education Initiative to Reduce Stigma Towards Sex Workers and Sexual Minorities Among Nursing Students sex workers and sexual minorities education workshop - Stigmatization, Sex Work | Not applicable | Completed | Hong Kong Metropolitan University | 32 | 2024-07-14 | 2025-05-13 |
| HIV/STD Risk and PrEP Implementation Messaging Among Gay, Bisexual, and Other Men Who Have Sex With Men Quantitative survey, HIV and STI testing, Qualitative Assessment - Sexually Transmitted Infections, Gay | Active not recruiting | Emory University | 675 | 2024-06-29 | 2026-07-24 | |
| Integrated Online-to-offline (O2O) Model of Care for HIV Prevention and Treatment Among Men Who Have Sex With Men Online to offline counseling - HIV Prevention Program | Not applicable | Active not recruiting | University of Connecticut | 78 | 2024-05-02 | 2026-10-13 |
| Transmasculine One-on-One and Group Empowerment for Targeted HIV Reduction PrEP4T, LS4TM - HIV Infections, Adherence, Medication | Not applicable | Active not recruiting | Fenway Community Health | 90 | 2024-04-01 | 2026-09-16 |
| Evaluating the Effectiveness of a Mobile HIV Prevention App to Increase HIV and Sexually Transmitted Infections (STI) Testing and PrEP Initiation Among Rural Men Who Have Sex With Men Combine mobile app, Motivational interview, HIV/STI testing - HIV Infections, STI | Not applicable | Active not recruiting | Emory University | 473 | 2024-03-27 | 2025-10-23 |
| Facilitating Routine HIV Testing Among MSM by a Subscription-based Self-test Distribution Model Text reminder, HIV self-test - Hiv | Not applicable | Active not recruiting | Chinese University of Hong Kong | 240 | 2024-01-15 | 2026-03-19 |
| Mycoplasma Genitalium Infection and Associated Antimicrobial Resistance Among HIV-infected Male in Hong Kong self-sampling kits for STI testing in the laboratory - STI, Mycoplasma Genitalium Infection | Completed | Chinese University of Hong Kong | 573 | 2023-07-24 | 2026-03-18 |
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HIV Infections (49) · Sexually Transmitted Diseases (26) · Acquired Immunodeficiency Syndrome (25) · Bisexuality (16) · Homosexuality, Male (13) · Homosexuality, Female (12) · Sexual Behavior (9) · Syphilis (9) · Coitus (8) · Anus Neoplasms (7) · Depression (7) · Substance-Related Disorders (7) · Gonorrhea (6) · Hepatitis C (5)
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Emory University (9) · Centers for Disease Control and Prevention (8) · Columbia University (8) · Chinese University of Hong Kong (7) · ANRS, Emerging Infectious Diseases (5) · National Institute of Allergy and Infectious Diseases (NIAID) (5) · University of California, San Francisco (5) · Medical College of Wisconsin (3) · University of Chicago (3) · University of Connecticut (3) · Ann & Robert H Lurie Children's Hospital of Chicago (2) · British Columbia Centre for Disease Control (2) · Charles Drew University of Medicine and Science (2) · Florida State University (2) · Hospitales Universitarios Virgen del Rocío (2)
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