11 completed, 3 not yet recruiting, 2 unknown, 1 recruiting. 19 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 19 | Completed 11, Not yet recruiting 3, Unknown 2, Recruiting 1, Suspended 1, Withdrawn 1 |
Follow Anesthesia, Spinal: new trials by email Literature Review of Anesthesia, Spinal trials Research Report on Anesthesia, Spinal
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparison of Low-Dose Versus Standard-Dose Hyperbaric Bupivacaine in Spinal Anesthesia Low-Dose Hyperbaric Bupivacaine, Standard-Dose Hyperbaric Bupivacaine - Anesthesia, Spinal, Orthopedic Procedures | Phase 4 | Not yet recruiting | Mayo Hospital Lahore | 180 | 2026-07-01 | 2026-07-13 |
| Haemodynamic Effects and Complications of Continuous Versus Single-shot Spinal Anaesthesia for HIP Fracture Surgery Bupivacaine Spinal 0,5% Heavy - bolus, Bupivacaine Spinal 0,5% Heavy - titration - Anesthesia, Spinal, Hip Fractures | Phase 4 | Not yet recruiting | Centre of Postgraduate Medical Education | 216 | 2026-01-15 | 2026-01-23 |
| D-FAB-POUR Trial: Dexmedetomidine vs Fentanyl as Adjuvants to Bupivacaine on Postoperative Urinary Retention Intervention 1: Intrathecal Dexmedetomidine with Bupivacaine, Intervention 2: Intrathecal Fentanyl with Bupivacaine - Spinal Anesthesia, Postoperative Complications | Phase 4 | Not yet recruiting | Tribhuvan University Teaching Hospital, Institute Of Medicine. | 190 | 2025-09-15 | 2025-08-12 |
| Comparing the Safety and Effectiveness of Different Doses of Morphine Administered in Spinal Anethesia for Pain Relief After Hip Replacement Surgery Spinal Anesthesia (bupivacaine), Postoperative pain management with acetaminophen, PCA IV Oxycodone - Analgesics, Opioid, Anesthesia, Spinal | Phase 4 | Recruiting | Medical University of Silesia | 120 | 2025-03-04 | 2026-02-12 |
| Intrathecal Dexmedetomidine vs Epinephrine Dexmedetomidine, Epinephrine, Standardized Spinal Mixture - Cesarean Section, Anesthesia, Spinal | Phase 4 | Completed | Icahn School of Medicine at Mount Sinai | 90 | 2024-09-17 | 2026-06-17 |
| Mepivacaine vs Bupivacaine Spinal Anesthesia for TKA Mepivacaine, Bupivacaine - Anesthesia, Spinal, Arthroplasty, Replacement, Knee | Phase 4 | Completed | Prisma Health-Upstate | 138 | 2024-02-16 | 2025-08-28 |
| Effect of Aromatherapy on Preoperative Anxiety Level lavender essential oil inhaled using cotton balls, lavender essential oil inhaled using face mask, Distilled water - Anxiety, Aromatherapy | Phase 4 | Completed | Mongi Slim Hospital | 90 | 2023-08-02 | 2024-07-18 |
| The Effect of Low-dose Atropine on Sympathetic Blockade in Spinal Cesarean Section Patients Slow dose preemptive Atropine, Ephedrine - Pregnancy, Cesarean Section | Phase 4 | Completed | Abant Izzet Baysal University | 60 | 2023-07-19 | 2023-10-11 |
| Comparison in Frequency of Hypotension Between Remimazolam and Propofol in Hip Surgery Remimazolam, Propofol - Remimazolam, Propofol | Phase 4 | Completed | Asan Medical Center | 78 | 2022-12-26 | 2025-02-26 |
| Effective Dose of Remimazolam for Sedation in Patients Undergoing Lower Extremity Surgery Under Spinal Anesthesia Remimazolam - Remimazolam, Orthopedic Procedures | Phase 4 | Completed | Asan Medical Center | 51 | 2022-05-11 | 2022-12-19 |
| Different Noradrenaline Protocols in Post Spinal Hypotension in CS Noradrenalin 10 microgram bolus, Noradrenaline 5 microgram bolus, Noradrenaline 0.1 microgram/kg/minute infusion - Hypotension, Cesarean Section | Phase 4 | Completed | Ankara University | 180 | 2021-02-01 | 2022-02-01 |
| Comparison of Clorotekal and Bupivacaine for Short Obstetric Surgery Chloroprocaine Injection [Clorotekal], Bupivacaine Hydrochloride 0.75% Injection Solution - Anesthesia, Spinal | Phase 4 | Suspended | Oregon Health and Science University | 27 | 2019-10-24 | 2024-06-21 |
| Atropine or Ephedrine Pretreatment for Preventing Bradycardia in Elderly Patients normal saline, atropine 0.5mg, ephedrine 8mg - Anesthesia, Spinal, Dexmedetomidine | Phase 4 | Completed | Ajou University School of Medicine | 102 | 2019-06-25 | 2021-02-04 |
| GA/Spinal vs. GA/Spinal/NMB for Operative Repair of Hip Fracture Rocuronium, Sugammadex, Normal saline - Hip Fractures, Anesthesia, Spinal | Phase 4 | Withdrawn | Loyola University | 2017-07-19 | 2019-08-20 | |
| Mepivacaine vs. Bupivacaine Spinal Anesthetic in Total Knee Arthroplasty Mepivacaine, Bupivacaine - Anesthesia, Spinal, Arthroplasty, Replacement, Knee | Phase 4 | Completed | Henry Ford Health System | 32 | 2016-12-01 | 2017-03-27 |
| Cardiac Output Changes During Hyperbaric and Isobaric Bupivacaine in Patients Undergoing Cesarean Section Isobaric marcaine, Hyperbaric marcaine - Cardiac Output, Hypotension | Phase 4 | Completed | Mahidol University | 168 | 2016-03-29 | 2017-07-31 |
| Intrathecal Dexmedetomidine With Bupivacaine for Spinal Anesthesia in Cesarean Section Dexmedetomidine & Bupivacaine., Bupivacaine Only. - Anesthesia, Spinal | Phase 4 | Completed | Cairo University | 120 | 2014-12-01 | 2016-02-02 |
| Paradoxical Excitement Response During Sedation Between Dexmedetomidine and Propofol in Hazardous Alcohol Drinker Dexmedetomidine, Propofol - Anesthesia, Spinal, Sedation, Conscious | Phase 4 | Unknown | Chonnam National University Hospital | 110 | 2013-12-01 | 2019-03-14 |
| Comparison of Standard and Minidose Spinal Anesthesia for Cesarean Section Operation Using Marcaine Spinal 0.5% Heavy Bupivacaine and Fentanyl, Bupivacaine - Cesarean Section, Anesthesia, Spinal | Phase 4 | Unknown | Bnai Zion Medical Center | 100 | 2011-02-01 | 2011-02-25 |
Hip Fractures (2) · Hypotension (2) · Agnosia (1) · Alcohol Drinking (1) · Anxiety Disorders (1) · Bradycardia (1) · Postoperative Complications (1)
Cardiovascular Diseases (3) · Pathological Conditions, Signs and Symptoms (3) · Femoral Fractures (2) · Fractures, Bone (2) · Hip Injuries (2) · Leg Injuries (2) · Pathologic Processes (2) · Vascular Diseases (2) · Wounds and Injuries (2) · Arrhythmias, Cardiac (1) · Behavior (1) · Drinking Behavior (1) · Heart Diseases (1) · Mental Disorders (1) · Nervous System Diseases (1)
Bupivacaine (8) · Dexmedetomidine (3) · Anesthesia, Spinal (2) · Atropine (2) · Ephedrine (2) · Mepivacaine (2) · Propofol (2) · Saline Solution (2) · remimazolam (2) · Acetaminophen (1) · Aromatherapy (1) · Dipyrone (1) · Epinephrine (1) · Fentanyl (1) · Monitoring, Physiologic (1)
Asan Medical Center (2) · Abant Izzet Baysal University (1) · Ajou University School of Medicine (1) · Ankara University (1) · Bnai Zion Medical Center (1) · Cairo University (1) · Centre of Postgraduate Medical Education (1) · Chonnam National University Hospital (1) · Henry Ford Health System (1) · Icahn School of Medicine at Mount Sinai (1) · Loyola University (1) · Mahidol University (1) · Mayo Hospital Lahore (1) · Medical University of Silesia (1) · Mongi Slim Hospital (1)
United States (5) · South Korea (4) · Poland (2) · Turkey (Türkiye) (2) · Israel (1) · Nepal (1) · Pakistan (1) · Thailand (1) · Tunisia (1)
Akcan Akkaya, MD. (1) · Boris Yanovsky, MD (1) · Brandon M Togioka, MD (1) · Daniel Katz, MD (1) · Hyunjung Lee, MD, Master (1) · Jason Davis, MD (1) · Jeongil Choi, MD, PhD (1) · Magdalena Fleming, MD (1) · Menekse Ozcelik, M.D (1) · Mhamed Sami MS Mebazaa, Pr (1) · Sirilak Suksompong, MD (1)
PMID 19713256, PMID 21903640, PMID 22436955, PMID 23748199, PMID 37892573