18 completed. 18 Phase 2, 3 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 18 | Completed 18 |
| Phase 3 | 3 | Completed 3 |
| Phase 1 | 2 | Completed 2 |
Follow Acute Stroke: new trials by email Literature Review of Acute Stroke trials Research Report on Acute Stroke
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation Study of Early Administration of Evolocumab After Thrombolysis in Patients With Atherosclerotic Acute Ischemic Stroke Ivolumab 420mg (three vials) - Acute Stroke | Phase 2 | Completed | The Affiliated Hospital of Xuzhou Medical University | 132 | 2025-10-30 | 2026-09-10 |
| Statin and Dual Antiplatelet Therapy to Prevent Early Neurological Deterioration in Branch Atheromatous Disease Clopidogrel, Aspirin, Atorvastatin - Acute Stroke, Dual Antiplatelet Therapy | Phase 2 | Completed | Chang Gung Memorial Hospital | 376 | 2021-03-23 | 2025-03-26 |
| Phase Ib/IIa Clinical Study of ApTOLL for the Treatment of Acute Ischemic Stroke ApTOLL, Placebo - Stroke, Acute Stroke | Phase 1 / Phase 2 | Completed | aptaTargets S.L. | 151 | 2020-10-28 | 2022-10-21 |
| Blood Pressure After Endovascular Stroke Therapy-II Nicardipine, Labetalol, Hydralazine - Acute Stroke, Endovascular Thrombectomy | Phase 2 | Completed | University of Cincinnati | 120 | 2020-01-17 | 2023-10-12 |
| Measuring Ambulation, Motor, and Behavioral Outcomes With Post-Stroke Fluoxetine in Tanzania Fluoxetine 20 MG Oral Tablet - Acute Stroke, Stroke, Ischemic | Phase 2 | Completed | Massachusetts General Hospital | 34 | 2019-11-26 | 2022-05-25 |
| PMZ-1620 (Sovateltide) in Acute Ischemic Stroke Patients Normal Saline along with standard treatment, PMZ-1620 along with standard treatment - Acute Stroke, Cerebral Ischemia | Phase 2 | Completed | Pharmazz, Inc. | 40 | 2018-01-19 | 2025-05-12 |
| Safety and Efficacy of Glibenclamide Combined With Rt-PA in Acute Cerebral Embolism Glibenclamide, Placebo - Acute Stroke | Phase 2 / Phase 3 | Completed | Nanfang Hospital, Southern Medical University | 306 | 2018-01-01 | 2023-06-12 |
| Blood Pressure Control in Acute Ischemic Stroke Early intensive BP control - Blood Pressure, Acute Stroke | Phase 2 / Phase 3 | Completed | National University of Singapore | 54 | 2014-12-01 | 2019-04-16 |
| PG2 Injection 500 mg in Acute Stroke Study (Pass) PG2, placebo - Acute Stroke | Phase 2 | Completed | China Medical University Hospital | 86 | 2012-06-01 | 2016-11-04 |
| Efficacy of Whole Extract of Licorice in Neurological Improvement of Patients After Acute Ischemic Stroke Licorice whole extract, Placebo - Acute Stroke | Phase 1 / Phase 2 | Completed | Shiraz University of Medical Sciences | 75 | 2012-06-01 | 2015-06-16 |
| PHANTOM-S: The Pre-Hospital Acute Neurological Therapy and Optimization of Medical Care in Stroke Patients - Study Stroke Emergency Mobile Unit (STEMO) - Acute Stroke | Phase 2 | Completed | Charite University, Berlin, Germany | 614 | 2011-05-01 | 2015-09-15 |
| A Study of Intravenous Thrombolysis With Alteplase in MRI-Selected Patients IV rt-PA - Acute Stroke | Phase 2 | Completed | Lee Schwamm | 88 | 2011-01-01 | 2017-06-15 |
| Mechanical Recanalization With Flow Restoration in Acute Ischemic Stroke Solitaire FR, ev3 - Acute Stroke | Phase 2 | Completed | Universität des Saarlandes | 40 | 2010-09-01 | 2011-12-02 |
| Intravenous Autologous Bone Marrow-derived Stem Cells Therapy for Patients With Acute Ischemic Stroke Autologous bone marrow stem cell - Acute Stroke | Phase 2 | Completed | Manipal Acunova Ltd. | 120 | 2008-10-01 | 2011-12-29 |
| Efficacy and Safety of Continuous Intravenous Versus Usual Subcutaneous Insulin in Acute Ischemic Stroke Insulin - Acute Stroke, Acute Cerebral Ischemia | Phase 2 / Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 180 | 2007-05-01 | 2014-06-05 |
| Beta-hCG + Erythropoietin in Acute Stroke Dual Growth Factor - Acute Stroke | Phase 2 | Completed | University of California, Irvine | 15 | 2006-08-01 | 2016-08-29 |
| SELESTIAL: Trial of Insulin to Control Blood Sugar After Acute Stroke Using Magnetic Resonance Imaging (MRI) End-Points Insulin - Acute Stroke, Hyperglycemia | Phase 2 | Completed | University of Glasgow | 45 | 2004-05-01 | 2006-02-01 |
| Robot Assisted Upper Limb Neuro-Rehabilitation Robot-assisted therapy, Traditional therapy - Acute Stroke | Phase 2 | Completed | US Department of Veterans Affairs | 60 | 2000-01-01 | 2008-03-11 |
Stroke (18) · Ischemic Stroke (8) · Brain Edema (1) · Brain Ischemia (1) · Cerebrovascular Disorders (1) · Hemiplegia (1) · Hyperglycemia (1) · Insulin Resistance (1)
Brain Diseases (18) · Cardiovascular Diseases (18) · Central Nervous System Diseases (18) · Nervous System Diseases (18) · Vascular Diseases (18) · Cerebrovascular Disorders (17) · Glucose Metabolism Disorders (2) · Metabolic Diseases (2) · Nutritional and Metabolic Diseases (2) · Hyperinsulinism (1) · Neurologic Manifestations (1) · Paralysis (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1)
Insulin (2) · Aspirin (1) · Atorvastatin (1) · Clopidogrel (1) · Fluoxetine (1) · Glyburide (1) · Hydralazine (1) · Labetalol (1) · Nicardipine (1) · Rosuvastatin Calcium (1) · TLR4 antagonist ApTOLL (1) · Tablets (1) · Tissue Plasminogen Activator (1) · sovateltide (1)
Assistance Publique - Hôpitaux de Paris (1) · Chang Gung Memorial Hospital (1) · Charite University, Berlin, Germany (1) · China Medical University Hospital (1) · Lee Schwamm (1) · Manipal Acunova Ltd. (1) · Massachusetts General Hospital (1) · Nanfang Hospital, Southern Medical University (1) · National University of Singapore (1) · Pharmazz, Inc. (1) · Shiraz University of Medical Sciences (1) · The Affiliated Hospital of Xuzhou Medical University (1) · US Department of Veterans Affairs (1) · University of California, Irvine (1) · University of Cincinnati (1)
United States (4) · Germany (3) · China (2) · France (2) · India (2) · Taiwan (2) · Iran (1) · Singapore (1) · Spain (1) · Tanzania (1) · United Kingdom (1)
Anil Gulati (1) · Charles Burgar, MD (1) · Chung Y. Hsu, PhD (1) · Dr. Kameshwar Prasad, MBBS, MD (1) · Dr. R.S Sarkar (1) · Dr. Sharat Joshi, MBBS,MD, DM (1) · Dr. Sudesh Kumar Prabhakar, MBBS, MD, DM (1) · Dr. Usha Kant Misra, MBBS, MD, DM (1) · Eva Mistry, MBBS (1) · Farrah J Mateen, MD, PhD (1) · Heinrich Audebert, Prof (1) · Keith Muir, MD (1) · Lawrence Latour, PhD (1) · Lee Schwamm, MD (1)
PMID 16614616, PMID 22700528, PMID 22960888, PMID 23523460, PMID 24756512, PMID 25378424, PMID 25402214, PMID 25634000, PMID 25793765, PMID 26251255, PMID 27328702, PMID 27834750, PMID 29689135, PMID 30290680, PMID 32527232, PMID 33428177, PMID 34174279, PMID 34836908, PMID 36908619, PMID 37338893, PMID 37668620, PMID 37965431, PMID 39314261, PMID 40726739, PMID 41583626
K23NS113858 (1)