60 completed, 18 recruiting, 17 unknown, 13 not yet recruiting. 31 Not applicable, 21 Phase 4, 13 Phase 3, 6 Phase 2, 3 Phase 1.
Follow Acute Coronary Syndromes: new trials by email Literature Review of Acute Coronary Syndromes trials Research Report on Acute Coronary Syndromes
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AI-ECG Detection of Occlusion Myocardial Infarction at Emergency Department Triage (TRIACS) Acute Coronary Syndromes, Chest Pain | Not yet recruiting | University Medical Centre Maribor | 1000 | 2026-10-19 | 2026-10-20 | |
| Smartphone AI Assistance for Prehospital ECG Interpretation Smartphone large language model assistance (GPT-4o, version-locked) - Acute Coronary Syndromes, ST Elevation Myocardial Infarction | Not applicable | Recruiting | École Supérieure de Soins Ambulanciers - College of Higher Education in Prehospital Care | 144 | 2026-09-02 | 2026-09-09 |
| triPle Oral thERapy With Bempedoic Acid vs uSual Care in Early Lipid Management of Patients With acUte coronAry synDromE Triple oral lipid lowering treatment - Acute Coronary Syndromes, Secondary Prevention | Phase 3 | Not yet recruiting | Heart Care Foundation | 600 | 2026-09-01 | 2026-02-27 |
| Early Triple Lipid-Lowering Therapy With Bempedoic Acid After Acute Coronary Syndrome bempedoic acid, Ezetimibe, High-Intensity Statin Therapy - Acute Coronary Syndromes, Dyslipidemia | Phase 4 | Recruiting | Taipei Medical University Hospital | 400 | 2026-08-26 | 2026-09-17 |
| Prospective Cohort of Acute Cardiology Referrals in an Ambulatory Day-Hospital Setting Acute Coronary Syndromes, Heart Failure | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 25000 | 2026-08-01 | 2026-06-30 | |
| Coronary Laser Atherectomy Registry From an International Taskforce Excimer Laser Coronary Atherectomy (ELCA) - Stable Coronary Artery Disease, Acute Coronary Syndromes | Recruiting | Ceric Sàrl | 500 | 2026-07-20 | 2026-07-23 | |
| Early Single Antiplatelet Therapy After IVUS-Guided PCI in Acute Coronary Syndrome Early P2Y12 Inhibitor Monotherapy, Standard Dual Antiplatelet Therapy - Acute Coronary Syndromes, STEMI | Phase 4 | Not yet recruiting | Gyeongsang National University Hospital | 1900 | 2026-07-01 | 2026-07-06 |
| Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors With Statin for ACS Patients PCSK9 inhibitor plus rosuvastatin 20 mg tab, Rosuvastatin 20 Mg Oral Tablet - Acute Coronary Syndromes | Phase 3 | Not yet recruiting | Assiut University | 120 | 2026-07-01 | 2026-07-30 |
| AI-Enhanced Single-Lead ECG Screening for Coronary Stenosis single-channel electrocardiogram - Ischemic Heart Disease, Coronary Artery Stenosis | Not yet recruiting | I.M. Sechenov First Moscow State Medical University | 400 | 2026-05-01 | 2026-05-12 | |
| Study of the Long-term Effects of P2Y12 Inhibitor Monotherapy and Coagulation Markers After Percutaneous Coronary Angioplasty. Clopidogrel, Ticagrelor, Prasugrel - Coronary Artery Disease, Percutaneous Coronary Intervention | Phase 3 | Recruiting | Cardiocentro Ticino | 355 | 2026-04-20 | 2026-05-13 |
| ALIGN-ACS Pilot Study ECG - Acute Coronary Syndromes | Active not recruiting | HeartBeam, Inc. | 120 | 2026-03-05 | 2026-07-20 | |
| Aspirin 50mg vs 100mg Combined With P2Y12 Inhibitor After PCI Aspirin, P2Y12 inhibitor - Coronary Artery Disease, Acute Coronary Syndromes | Not applicable | Recruiting | Jilin University | 2640 | 2026-03-01 | 2026-10-01 |
| AI-Assisted Coronary Syndrome Subtyping From Admission History of Present Illness: A Clinician Reader Study OCR-Prompt-LLM Information Extraction and Classification Workflow (OCR-Prompt-LLM), Manual Clinical Data Review - Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)), Acute Coronary Syndromes | Completed | China National Center for Cardiovascular Diseases | 10 | 2026-02-28 | 2026-10-27 | |
| Bivalirudin Versus Heparin During PCI in High Bleeding Risk Patients With Acute Coronary Syndromes Anticoagulant Therapy - Percutaneous Coronary Intervention, High Bleeding Risk | Phase 4 | Not yet recruiting | Shenyang Northern Hospital | 5270 | 2026-02-01 | 2026-02-03 |
| Impact of Non-medicalized ECG Practices Initiated by SAMU in Dispatch Strategies ECG by the SMUR after medical interrogation by the SAMU, ECG performed by a non-medical vector - Acute Coronary Syndromes | Not yet recruiting | Centre Hospitalier Sud Francilien | 350 | 2026-02-01 | 2025-12-16 | |
| EARLY: Educational Intervention to Improve Patient Awareness on Early LDL-C Lowering in Secondary Prevention Patient-oriented educational intervention - Acute Coronary Syndromes, Chronic Coronary Syndromes | Not applicable | Not yet recruiting | Heart Care Foundation | 240 | 2025-12-11 | 2025-11-26 |
| Evaluation of the Effectiveness of an Interdisciplinary Intervention After Acute Coronary Syndrome on Low-Density Lipoprotein Cholesterol Levels "New" care pathway, "Standard" care pathway - Acute Coronary Syndromes (ACS), Acute Coronary Syndromes | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 230 | 2025-11-01 | 2025-10-03 |
| Oregano and Basil Leaves and Coronary Artery Disease Control (Standard treatment), Higher polyphenol intake by consumption of oregano and basil - Acute Coronary Syndromes, Unstable Angina (UA) | Not applicable | Recruiting | Shahid Beheshti University of Medical Sciences | 70 | 2025-09-01 | 2026-06-16 |
| Focused Orticumab Research for Treating Inflammation in Coronary Arteries Orticumab, Placebo - Acute Coronary Syndromes, Coronary Arterial Disease (CAD) | Phase 2 | Recruiting | Abcentra | 240 | 2025-08-11 | 2026-01-27 |
| Point-of-Care Troponin Testing in the Emergency Department Point-of-Care high-sensitivity troponin testing - Acute Coronary Syndromes | Not applicable | Active not recruiting | KU Leuven | 1552 | 2025-06-30 | 2026-10-21 |
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Acute Coronary Syndrome (118) · Myocardial Infarction (15) · Coronary Artery Disease (13) · ST Elevation Myocardial Infarction (13) · Non-ST Elevated Myocardial Infarction (11) · Angina, Unstable (9) · Heart Failure (5) · Myocardial Ischemia (5) · Angina Pectoris (4) · Chest Pain (4) · Inflammation (4) · Arrhythmias, Cardiac (3) · Atherosclerosis (3) · Dyslipidemias (3) · Heart Diseases (3)
Vascular Diseases (118) · Cardiovascular Diseases (117) · Heart Diseases (115) · Myocardial Ischemia (113) · Pathological Conditions, Signs and Symptoms (46) · Pathologic Processes (36) · Ischemia (27) · Necrosis (26) · Infarction (25) · Signs and Symptoms (20) · Neurologic Manifestations (18) · Pain (18) · Arterial Occlusive Diseases (16) · Arteriosclerosis (16) · Chest Pain (14)
Clopidogrel (13) · Prasugrel Hydrochloride (7) · Atorvastatin (6) · Aspirin (5) · Rosuvastatin Calcium (5) · Ticagrelor (5) · Tirofiban (3) · Cilostazol (2) · Tablets (2) · aldesleukin (2) · 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid (1) · Adrenergic beta-Antagonists (1) · Angiotensin-Converting Enzyme Inhibitors (1) · Bisoprolol (1) · Blood Specimen Collection (1)
AstraZeneca (5) · Shenyang Northern Hospital (5) · Assistance Publique - Hôpitaux de Paris (3) · Assiut University (3) · Eli Lilly and Company (3) · Heart Care Foundation (3) · Assistance Publique Hopitaux De Marseille (2) · Bristol-Myers Squibb (2) · Cambridge University Hospitals NHS Foundation Trust (2) · Medicure (2) · Sheba Medical Center (2) · The George Institute for Global Health, China (2) · University Hospital of Ferrara (2) · University of Zurich (2) · Xijing Hospital (2)
China (19) · Italy (18) · United States (16) · France (8) · United Kingdom (8) · Canada (7) · Germany (7) · Spain (7) · Sweden (7) · Switzerland (7) · Turkey (Türkiye) (7) · Hungary (6) · Poland (6) · Belgium (5) · Brazil (5)
Alan S Maisel, MD (2) · Christian Mueller, MD (2) · Furio Colivicchi, MD (2) · Sanjit S Jolly, MD (2) · Steven V Manoukian, MD (2) · Yaling Han, M.D. (2) · Aldo P Maggioni, MD (1) · Aleksandra Djokovic, MD, PhD (1) · Ali Hussnain (1) · Anggoro Budi Hartopo, PhD (1) · Arif O Cimen, M.D. (1) · Ashraf Al Azzoni, MD (1)
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2014 (1), 2017 (1), R01MH100332 (1)