33 completed, 17 unknown, 12 recruiting, 9 terminated. 35 Not applicable, 8 Phase 2, 7 Phase 4, 2 Phase 1, 1 Early Phase 1.
Follow Achalasia: new trials by email Literature Review of Achalasia trials Research Report on Achalasia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Disposable Endoscope Platform in Third Space Endoscopic Procedures (Esophageal or Gastric) Per-Oral Endoscopic Myotomy - Achalasia, Gastroparesis | Withdrawn | Baylor College of Medicine | 2026-12-30 | 2026-10-01 | ||
| Impact of Body Positioning on EndoFLIP Measurements: A Comparative Study of Supine and Left Lateral Decubitus Positions EndoFlip - Dysphagia, Esophageal Stricture | Not applicable | Recruiting | Johns Hopkins University | 25 | 2026-07-24 | 2026-08-24 |
| PRospective Registry of Esophageal Motility No intervention - Esophageal Diseases, Achalasia | Recruiting | IRCCS San Raffaele | 10000 | 2026-03-09 | 2026-04-02 | |
| Clinical Outcomes, Safety, and Effectiveness of Speedboat UltraSlim™ in Per-Oral Endoscopic Myotomy (POEM) Esophageal Motility Disorders, Achalasia | Recruiting | Baylor College of Medicine | 40 | 2026-01-15 | 2026-06-17 | |
| Full-thickness Versus Progressive Myotomy in Peroral Endoscopic Esophageal Myotomy in Achalasia: A Randomized Controlled Trial Full thickness myotomy, Progressive thickness myotomy - Achalasia Cardia, Achalasia | Phase 2 | Recruiting | Cairo University | 70 | 2025-08-01 | 2026-10-15 |
| Safety and Efficacy of a Novel SpydrBlade Flexible Bipolar in POEM SpydrBlade Flex - Achalasia, EGJ Outflow Obstruction | Not applicable | Recruiting | Chinese University of Hong Kong | 73 | 2024-11-01 | 2026-02-12 |
| Electrosurgical Modes for Endoscopic Submucosal Dissection in Peroral Endoscopic Esophageal Myotomy endoscopic submucosal dissection using SPRAY COAG mode, endoscopic submucosal dissection using Precisect mode - Achalasia, Achalasia Cardia | Phase 3 | Recruiting | Cairo University | 52 | 2024-03-16 | 2025-05-13 |
| POEM-F for Achalasia International Study POEM-F, Conventional POEM - Achalasia | Not applicable | Recruiting | Chinese University of Hong Kong | 81 | 2023-12-01 | 2024-12-03 |
| redoPOEM : Failure of a First POEM Achalasia | Completed | University Hospital, Bordeaux | 111 | 2023-10-03 | 2024-07-10 | |
| Prospective Collection of Outcome Data Post POEM-TIF Procedure POEM-TIF - Achalasia, Gastroesophageal Reflux Disease | Withdrawn | Johns Hopkins University | 2023-07-01 | 2023-07-28 | ||
| Autonomic Dysfunction and Hemodynamic Instability During Per-oral Endoscopic Myotomy Per-oral endoscopic myotomy - Achalasia | Completed | Gangnam Severance Hospital | 41 | 2023-04-03 | 2026-07-22 | |
| VZV in the Enteric Nervous System: Pathogenesis and Consequences ValACYclovir 1000 MG, Shingrix - Achalasia | Phase 4 | Recruiting | Vanderbilt University Medical Center | 40 | 2023-03-27 | 2026-10-05 |
| The Use of Indocyanine Green Fluorescence (ICG) During Laparoscopic Heller- Dor Achalasia, Esophageal, Achalasia | Recruiting | Federico II University | 70 | 2022-11-01 | 2025-09-23 | |
| POEM + F for Achalasia - a Pilot Study POEM + F - Achalasia | Not applicable | Unknown | Chinese University of Hong Kong | 10 | 2022-03-24 | 2023-09-07 |
| The Effect of Physiotherapy on Post POEM Reflux Physiotherapy, Control group - Reflux, Gastroesophageal, Achalasia | Not applicable | Unknown | Institute for Clinical and Experimental Medicine | 30 | 2021-10-31 | 2024-03-07 |
| Prospective Evaluation of the Clinical Utility of Peroral Endoscopic Myotomy for Gastrointestinal Motility Disorders Achalasia, Esophageal Spasm, Diffuse | Recruiting | AdventHealth | 600 | 2021-10-01 | 2026-02-02 | |
| Analysis of Prevalence and Risk Factors Associated With Gastroesophageal Reflux Disease and Esophagitis After Peroral Endoscopic Myotomy Patients who underwent POEM - Achalasia, GERD | Unknown | Maria Sklodowska-Curie National Research Institute of Oncology | 100 | 2021-06-01 | 2021-10-18 | |
| ConMed Beamer Study Gastrointestinal Neoplasms, Achalasia | Completed | Baylor College of Medicine | 60 | 2021-05-27 | 2022-05-27 | |
| Transoral Incisionless Fundoplication in Post-POEM GERD Swallowing Disorders, Achalasia | Completed | Baylor College of Medicine | 7 | 2021-03-17 | 2023-08-18 | |
| Comprehensive Esophageal Diagnostics Study Atropine challenge, Esophageal muscle biopsy - Achalasia | Phase 4 | Recruiting | Emory University | 80 | 2021-03-17 | 2026-09-16 |
Showing 20 of 81. Sign in to see all of them.
Esophageal Achalasia (81) · Deglutition Disorders (16) · Gastroesophageal Reflux (11) · Gastroparesis (4) · Esophageal Motility Disorders (3) · Esophageal Spasm, Diffuse (3) · Eosinophilic Esophagitis (2) · Esophagitis (2) · Fistula (2) · Gastric Outlet Obstruction (2) · Zenker Diverticulum (2) · Alacrima (1) · Carcinoma, Squamous Cell (1) · Chest Pain (1) · Constriction, Pathologic (1)
Digestive System Diseases (81) · Gastrointestinal Diseases (81) · Esophageal Diseases (80) · Esophageal Motility Disorders (78) · Deglutition Disorders (65) · Otorhinolaryngologic Diseases (16) · Pharyngeal Diseases (16) · Pathological Conditions, Signs and Symptoms (10) · Signs and Symptoms (8) · Gastroenteritis (6) · Neurologic Manifestations (6) · Stomach Diseases (6) · Paralysis (4) · Pathological Conditions, Anatomical (4) · Diverticular Diseases (2)
Heller Myotomy (4) · Endoscopy (3) · nephronectin (3) · 1-palmitoyl-2-oleoylphosphatidylethanolamine (1) · Adrenal Cortex Hormones (1) · Amyl Nitrite (1) · Anesthesia, General (1) · Botulinum Toxins, Type A (1) · Conservative Treatment (1) · Control Groups (1) · Domperidone (1) · Enteral Nutrition (1) · Esomeprazole (1) · Fentanyl (1) · Fundoplication (1)
Chinese University of Hong Kong (5) · Mayo Clinic (5) · Baylor College of Medicine (4) · Johns Hopkins University (4) · Universitätsklinikum Hamburg-Eppendorf (3) · Vanderbilt University Medical Center (3) · Asan Medical Center (2) · Cairo University (2) · Federico II University (2) · Istituto Clinico Humanitas (2) · Karolinska University Hospital (2) · Northwestern University (2) · The Oregon Clinic (2) · Advanced Endoscopy Research, Robert Wood Johnson Medical School Rutgers University (1) · AdventHealth (1)
United States (40) · Italy (8) · Hong Kong (5) · Canada (4) · Sweden (4) · China (3) · Germany (3) · Belgium (2) · Czechia (2) · Egypt (2) · France (2) · Netherlands (2) · South Korea (2) · United Kingdom (2) · Brazil (1)
Hon Chi Yip, FRCSEd (2) · Karthik Ravi, MD (2) · Mohamed Othman, MD (2) · Thomas Roesch, Prof. Dr. (2) · Alessandro Repici, MD (1) · Alexander S Rosemurgy, MD (1) · Anand Jain, MD (1) · Anders Thorell, Professor (1) · Andrew JE Seely, MD, PhD (1) · Antoine Debourdeau (1) · C.T. Germer, Prof. (1)
PMID 20354937, PMID 11413123, PMID 15633138, PMID 15930992, PMID 16675239, PMID 18722376, PMID 19028319, PMID 19072391, PMID 21111876, PMID 22068665, PMID 23043852, PMID 23105999, PMID 23394838, PMID 23549760, PMID 23665071, PMID 23871090, PMID 23877351, PMID 23891074, PMID 23973923, PMID 24074429, PMID 24892729, PMID 25088923, PMID 25409838, PMID 25469569, PMID 25934759, PMID 26907745, PMID 27513156, PMID 27609778, PMID 27747277, PMID 27756611, PMID 28989059, PMID 29315993, PMID 29410304, PMID 29546671, PMID 29972404, PMID 30054739, PMID 31408652, PMID 31800987, PMID 33373111, PMID 34115014, PMID 34119499, PMID 34979118, PMID 35467562, PMID 35947304, PMID 35997700, PMID 36509112, PMID 37072180, PMID 40112837, PMID 41051511, PMID 41575544
K23DK131317 (1), R03DK145962 (1)