31 completed, 5 terminated, 4 withdrawn, 2 active not recruiting. 43 Phase 3, 12 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 43 | Completed 31, Terminated 5, Withdrawn 4, Active not recruiting 2, Unknown 1 |
| Phase 2 | 12 | Completed 9, Withdrawn 2, Terminated 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| REVERSE-Long COVID-19 With Baricitinib Study Baricitinib 4 MG, Placebo - Post-Acute COVID-19 Syndrome | Phase 3 | Withdrawn | Vanderbilt University Medical Center | 2024-10-21 | 2026-09-09 | |
| Improving Outcomes in Depression in Primary Care in a Low Resource Setting Healthy Activity Program (HAP), Antidepressant medication (fluoxetine) - Depression, Depressive Disorder | Phase 3 | Active not recruiting | Harvard Medical School (HMS and HSDM) | 1500 | 2024-03-18 | 2026-05-22 |
| Oral N-acetylcysteine for Retinitis Pigmentosa N-acetylcysteine, Placebo - Retinitis Pigmentosa | Phase 3 | Active not recruiting | Johns Hopkins University | 485 | 2023-10-11 | 2026-06-15 |
| OptimizeD Pilot Study Healthy Activity Program (HAP), Antidepressant medication (ADM) - Depression, Depressive Disorder | Phase 3 | Completed | Harvard Medical School (HMS and HSDM) | 76 | 2023-08-01 | 2024-04-09 |
| High-dose Erythropoietin for Asphyxia and Encephalopathy Normal saline placebo, Erythropoietin - Neonatal Encephalopathy, Birth Asphyxia | Phase 3 | Completed | University of California, San Francisco | 500 | 2017-01-01 | 2023-01-30 |
| Risk of Oxygen During Cardiac Surgery Trial Oxygen - normoxia, Oxygen - hyperoxia - Cardiac Surgery | Phase 2 / Phase 3 | Completed | Vanderbilt University | 213 | 2016-04-05 | 2024-02-01 |
| Energy Balance & Weight Loss in Craniopharyngioma-related or Other Hypothalamic Tumors in Hypothalamic Obesity Exenatide, placebo - Hypothalamic Obesity | Phase 3 | Completed | Seattle Children's Hospital | 42 | 2016-03-01 | 2022-05-05 |
| 2% Chlorhexidine Gluconate Skin Cloths to Prevent SSI in Spine Surgery Patients 2% chlorhexidine gluconate cloths - Surgical Site Infections, Post Operative Complication | Phase 3 | Completed | Vanderbilt University | 158 | 2015-08-01 | 2021-01-06 |
| The CSF Shunt Entry Site Trial Ventriculoperitoneal shunt insertion surgery - Hydrocephalus | Phase 3 | Unknown | Baylor College of Medicine | 448 | 2015-04-01 | 2020-11-12 |
| PreHospital Air Medical Plasma Trial infusion of 2 units of plasma - Hemmorhagic Shock During Air Medical Transport | Phase 3 | Completed | Jason Sperry | 523 | 2014-05-01 | 2021-04-08 |
| Treatment of Overweight Induced by Antipsychotic Medication in Young People With Autism Spectrum Disorders (ASD) Metformin, Placebo - Overweight, Autism Spectrum Disorder | Phase 3 | Completed | Holland Bloorview Kids Rehabilitation Hospital | 60 | 2013-04-01 | 2025-07-16 |
| Telemedicine in Patients With Inflammatory Bowel Disease (TELE-IBD) Home Monitoring - Inflammatory Bowel Disease, Crohn's Disease | Phase 3 | Completed | University of Maryland, Baltimore | 348 | 2012-09-01 | 2019-09-16 |
| Evaluating the Effectiveness of Intravenous Immunoglobulin Therapy in Autoimmune Autonomic Ganglionopathy Double blinded IVIg, Double blinded Placebo, Single Blinded IVIg - Autoimmune Autonomic Ganglionopathy (AAG) | Phase 2 / Phase 3 | Completed | Beth Israel Deaconess Medical Center | 6 | 2012-02-01 | 2017-07-02 |
| Study of Keto Acid (KA) on Insulin Resistance in Peritoneal Dialysis (PD) Patients Keto Acid - Insulin Resistance | Phase 3 | Completed | Peking University First Hospital | 100 | 2011-04-01 | 2014-02-21 |
| Study of Rifampicin in Multiple System Atrophy Rifampicin, placebo - Multiple System Atrophy | Phase 3 | Terminated | Phillip Low | 100 | 2011-03-01 | 2014-03-28 |
| Randomized Controlled Trial of Silymarin in Asthma Oral Silymarin, Oral Silymarin, maintenance dose, Placebo - Atopic Asthma | Phase 2 / Phase 3 | Withdrawn | Vanderbilt University | 2010-09-01 | 2014-02-24 | |
| Genes, Fibrinolysis and Endothelial Dysfunction- Dialysis Aim 3 valsartan (ARB), ramipril (ACE inhibitor), Placebo - Oxidative Stress, Endothelial Dysfunction | Phase 3 | Terminated | Vanderbilt University | 78 | 2010-01-01 | 2016-02-15 |
| Treatment of Traumatic Brain Injury (TBI)-Related Attention Deficits Vyvanse, fMRI, Placebo - Traumatic Brain Injury, Attention Deficit Disorder | Phase 3 | Terminated | Vanderbilt University | 22 | 2009-10-01 | 2017-05-19 |
| Prophylactic Probiotics in Premature Infants Lactobacillus reuteri, Placebo - Death, Nosocomial Infection | Phase 3 | Terminated | Colombian Neonatal Research Network | 751 | 2008-08-01 | 2011-06-22 |
| High Fat Diet: Oxidative and Cardiovascular Effects Placebo, MUFA, PUFA - Obesity | Phase 3 | Completed | Vanderbilt University | 144 | 2008-08-01 | 2020-11-10 |
Showing 20 of 43. Sign in to see all of them.
Obesity (5) · Depressive Disorder (3) · Renal Insufficiency (3) · Autonomic Nervous System Diseases (2) · Depression (2) · Depressive Disorder, Major (2) · Hypotension, Orthostatic (2) · Laryngeal Diseases (2) · Orthostatic Intolerance (2) · Acquired Immunodeficiency Syndrome (1) · Arrhythmias, Cardiac (1) · Asphyxia Neonatorum (1) · Asthma (1) · Atrial Fibrillation (1) · Attention Deficit Disorder with Hyperactivity (1)
Angiotensin-Converting Enzyme Inhibitors (2) · Antidepressive Agents (2) · Ramipril (2) · Saline Solution (2) · Sertraline (2) · Acetylcysteine (1) · Aminocaproic Acid (1) · Amoxicillin (1) · Aspirin (1) · Aspirin, Dipyridamole Drug Combination (1) · Blood Glucose Self-Monitoring (1) · Carbidopa (1) · Citrulline (1) · Clarithromycin (1) · Clopidogrel (1)
United States (36) · Canada (3) · Colombia (2) · India (2) · Austria (1) · China (1) · Germany (1) · Netherlands (1) · Switzerland (1) · United Kingdom (1)
Richard C Shelton, MD (3) · Alfonso Torquati, M.D. (2) · Catherine Meyers, M.D. (2) · David Robertson, MD (2) · Heidi J Silver, PhD (2) · John W Kusek, Ph.D. (2) · Alfredo J Gamboa, MD (1) · Benjamin Handen, Ph.D. (1) · Christian Roth, MD (1) · David W Haas, MD (1) · E. Wesley Ely, MD, MPH (1) · Eric Butter, Ph.D. (1) · Evdokia Anagnostou, M.D. (1) · Frederic T. Billings, IV, MD, MSc (1) · Fredrick E. Barr, MD, MSCI (1)
PMID 18477783, PMID 35224730, PMID 17196045, PMID 18824641, PMID 19298337, PMID 19458364, PMID 19799842, PMID 20599398, PMID 21242788, PMID 22626819, PMID 22824930, PMID 22869834, PMID 23071204, PMID 23361105, PMID 24349334, PMID 24507091, PMID 24559846, PMID 25468655, PMID 25812483, PMID 26220293, PMID 27556593, PMID 28651648, PMID 28942807, PMID 29382504, PMID 30044935, PMID 31851290, PMID 32229722, PMID 33057642, PMID 34144032, PMID 34298589, PMID 35830641, PMID 35861072, PMID 37019334, PMID 37418263, PMID 37698478, PMID 37742617, PMID 38006967, PMID 38360261, PMID 38933603, PMID 38984984, PMID 39110454, PMID 39878152, PMID 40470239, PMID 40673571, PMID 40739549, PMID 41282901, PMID 42386129, PMID 42635483
R01MH121632 (2), U01DK058982 (2), U54NS065736 (2), 1UG1EY033293 (1), K23DK075907 (1), P01HL056693 (1), P01NS044233 (1), R01GM112871 (1), R01HL043167 (1), R01HL065193 (1), R01HL073317 (1), R01HL077389 (1)