58 completed, 12 terminated, 8 withdrawn, 2 active not recruiting. 81 Phase 2, 12 Phase 3, 9 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Maximizing Outcomes for Preschoolers With Developmental Language Disorders the Enhanced Milieu Teaching-Sentence Focus - Developmental Language Disorder | Phase 2 | Completed | Northwestern University | 108 | 2019-04-04 | 2026-08-19 |
| Nitroglycerin vs. Furosemide Using Lung Ultrasound Pilot Trial Nitrates, Loop Diuretics - Heart Failure, Heart Failure Acute | Phase 2 | Terminated | Indiana University | 52 | 2017-12-14 | 2024-08-20 |
| Pulmonary Hypertension and Anastrozole Trial Anastrozole, Placebo Oral Tablet - Pulmonary Arterial Hypertension | Phase 2 | Completed | University of Pennsylvania | 84 | 2017-12-07 | 2024-05-01 |
| Ruxolitinib + Allogeneic Stem Cell Transplantation in AML Ruxolitinib - Acute Myeloid Leukemia, Acute Myeloid Leukemia in Remission | Phase 2 | Active not recruiting | Massachusetts General Hospital | 64 | 2017-11-03 | 2026-03-27 |
| A Biomarker Study in Advanced Mucosal or Acral Lentiginous Melanoma Receiving Nivolumab in Combination With Ipilimumab Nivolumab, Ipilimumab - Acral Lentiginous Melanoma, Mucosal Melanoma | Phase 2 | Terminated | Georgetown University | 14 | 2017-07-26 | 2024-04-04 |
| B-lines Lung Ultrasound Guided ED Management of Acute Heart Failure Pilot Trial LUS-guided strategy-of-care, Usual Care, Intravenous Loop Diuretic - Heart Failure, Heart Failure Acute | Phase 2 | Completed | Indiana University | 130 | 2017-07-10 | 2024-06-04 |
| Trial of Brigatinib After Treatment With Next-Generation ALK Inhibitors brigatinib - Non-Small Cell Lung Cancer | Phase 2 | Terminated | Criterium, Inc. | 32 | 2017-03-09 | 2023-01-26 |
| Memory Improvement Through Nicotine Dosing (MIND) Study Nicotine Transdermal Patch, Placebo Patch - Mild Cognitive Impairment | Phase 2 | Completed | University of Southern California | 348 | 2017-02-22 | 2026-09-17 |
| Interventions for Reading Disabilities in NF1 Lovastatin, reading tutoring intervention, Placebo Oral Tablet - Neurofibromatosis Type 1, Learning Disability | Phase 2 | Active not recruiting | Vanderbilt University | 120 | 2016-11-01 | 2026-07-01 |
| New Formulations of Propafenone to Treat Atrial Fibrillation (R)-propafenone, (S)-Propafenone, Placebo - Atrial Fibrillation | Phase 1 / Phase 2 | Terminated | Vanderbilt University | 193 | 2016-10-01 | 2022-06-03 |
| Macrolide Therapy to Improve Forced Expiratory Volume in 1 Second in Adults With Sickle Cell Disease Azithromycin, Placebo - Sickle Cell Disease | Phase 1 / Phase 2 | Withdrawn | Vanderbilt University | 2016-09-01 | 2018-10-02 | |
| A Randomized Trial of a Combination of Nintedanib/Placebo in Combination With Induction Chemotherapy for Patients With Refractory or First Relapse Acute Myeloid Leukemia Nintedanib and AML induction - Relapsed/Refractory Acute Myeloid Leukemia | Phase 2 | Completed | Yale University | 25 | 2016-07-21 | 2022-04-08 |
| Risk of Oxygen During Cardiac Surgery Trial Oxygen - normoxia, Oxygen - hyperoxia - Cardiac Surgery | Phase 2 / Phase 3 | Completed | Vanderbilt University | 213 | 2016-04-05 | 2024-02-01 |
| Carboplatin Plus Etoposide With or Without MPDL3280A in Untreated Extensive Stage Small Cell Lung Cancer Carboplatin, Etoposide, MPDL3280A - Small Cell Lung Cancer ( SCLC ) | Phase 1 / Phase 2 | Terminated | Giuseppe Giaccone | 1 | 2016-03-01 | 2018-07-02 |
| Trial of Oral Glutamine on Mitochondrial Function in CKD First Intervention (14 days), Washout (3 weeks), Second Intervention (14 days) - Cardiovascular Disease, Sarcopenia | Phase 2 | Completed | University of Washington | 11 | 2016-02-25 | 2022-07-14 |
| Contrast-enhanced Ultrasound of the Kidney Perflutren lipid microsphere - Chronic Kidney Disease, Cystic Kidney Disease | Phase 2 | Completed | University of North Carolina, Chapel Hill | 63 | 2016-02-01 | 2019-09-26 |
| The SCCS Polypill Pilot Trial Polypill (atorvastatin, amlodipine, losartan, and hydrochlorothiazide) - Hypertension, Hyperlipidemia | Phase 2 | Completed | Vanderbilt University | 303 | 2015-12-01 | 2021-05-14 |
| KIR Favorable Mismatched Haplo Transplant and KIR Polymorphism in ALL/AML/MDS Allo-HCT Children CliniMacs TCR alpha-beta-Biotin system - Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia | Phase 2 | Enrolling by invitation | Michael Pulsipher | 50 | 2015-10-01 | 2025-05-04 |
| Early Aldosterone Blockade in Acute Heart Failure: An Exploratory Safety Study Spironolactone, Placebo - Acute Heart Failure | Phase 2 | Withdrawn | Indiana University | 2015-05-01 | 2017-04-21 | |
| Safety and Cardiovascular Efficacy of Spironolactone in Dialysis-Dependent ESRD Trial Spironolactone - End-Stage Renal Disease | Phase 2 | Completed | University of Pennsylvania | 129 | 2014-11-01 | 2019-07-23 |
Showing 20 of 81. Sign in to see all of them.
Kidney Failure, Chronic (12) · Renal Insufficiency, Chronic (6) · Cognitive Dysfunction (3) · Delirium (3) · Inflammation (3) · Leukemia, Myeloid, Acute (3) · Acute Kidney Injury (2) · Atrial Fibrillation (2) · Autonomic Nervous System Diseases (2) · Breast Neoplasms (2) · Cardiovascular Diseases (2) · Depression (2) · Depressive Disorder, Major (2) · HIV Infections (2) · Heart Defects, Congenital (2)
Dietary Supplements (4) · Exercise (4) · Spironolactone (4) · Azithromycin (3) · Citrulline (3) · Dexmedetomidine (2) · Diet (2) · Ethambutol (2) · Gamma Rays (2) · Levofloxacin (2) · Raltegravir Potassium (2) · Ramipril (2) · Rifampin (2) · Saline Solution (2) · Thioctic Acid (2)
United States (78) · Canada (1)
Alp Ikizler, MD (16) · Jonathan Himmelfarb, MD (3) · E Wesley Ely, MD, MPH (2) · Peter S Pang, MD (2) · Albert C. Lockhart, M.D. (1) · Alfredo J Gamboa, MD (1) · Allen Pantuck, MD (1) · Andrew Winokur, M.D. (1) · Ann Kaiser, PhD (1) · Ben Shoemaker, MD (1) · Beth Malow, M.D., M.S. (1) · Bettie M Steinberg, PhD (1) · Bjorn Knollmann, MD/PhD (1) · Brian W. Christman, MD (1) · Christian Lattermann, MD (1)
PMID 32390133, PMID 11739090, PMID 14678952, PMID 15213282, PMID 17227907, PMID 17662768, PMID 18073360, PMID 18513353, PMID 18711110, PMID 18824641, PMID 20095068, PMID 20233428, PMID 20599398, PMID 21242788, PMID 22158433, PMID 22626819, PMID 22823027, PMID 22824930, PMID 22869834, PMID 23013802, PMID 23290327, PMID 23361105, PMID 23863960, PMID 24349334, PMID 25232828, PMID 25424850, PMID 25468655, PMID 25659187, PMID 26494370, PMID 27089159, PMID 27279368, PMID 28146402, PMID 28651648, PMID 29137655, PMID 29363356, PMID 29746485, PMID 30033738, PMID 30448355, PMID 31532959, PMID 31810978, PMID 33039599, PMID 33586138, PMID 34246609, PMID 34291724, PMID 35018639, PMID 35435017, PMID 35776909, PMID 35963181, PMID 36166682, PMID 37156670
R01DK045604 (3), K23DK099442 (1), P01HL056693 (1), R01AG047992 (1), R01CA160938 (1), R01GM112871 (1), R01HD089474 (1), R01HL065193 (1), R01HL073317 (1), R01HL077389 (1), R01HL117074 (1), R01HL124935 (1), R01HL134905 (1), R01MH077596 (1), R01NS042698 (1)