8 completed, 2 unknown, 1 recruiting. 2 Not applicable, 2 Phase 2, 1 Early Phase 1, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Completed 2 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
| Early Phase 1 | 1 | Recruiting 1 |
| Phase 1 | 1 | Unknown 1 |
| Phase 3 | 1 | Unknown 1 |
Follow Withdrawal: new trials by email Literature Review of Withdrawal trials Research Report on Withdrawal
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of the Electronic Cigarette Withdrawal Syndrome Transdermal Nicotine Patch, Placebo Nicotine Patch - E-cigarette Use, Withdrawal | Early Phase 1 | Recruiting | Johns Hopkins University | 150 | 2023-11-28 | 2026-07-15 |
| Effect of Diuretics Withdrawal in Chronic Heart Failure With Reduced Ejection Fraction Diuretics withdrawal, Diuretics maintenance - Heart Failure, Electric Impedance | Phase 2 | Completed | Maimónides Biomedical Research Institute of Córdoba | 98 | 2022-12-19 | 2024-11-04 |
| Impact of Tapering Immunosuppressants on Maintaining Minimal Disease Activity in Adult Subjects With Psoriatic Arthritis Prednisolone, Sulfasalazine, Leflunomide - Psoriatic Arthritis, Withdrawal | Phase 3 | Unknown | University of Erlangen-Nürnberg Medical School | 270 | 2020-10-19 | 2022-11-14 |
| Evaluation of the Management of Tramadol Use Disorders Withdrawal | Completed | University Hospital, Montpellier | 50 | 2020-09-17 | 2021-10-25 | |
| Feasibility of Auricular Acupressure as an Adjunct Treatment for Neonatal Abstinence Syndrome (NAS) Auricular acupuncture - Neonatal Abstinence Syndrome, Withdrawal | Not applicable | Completed | Vanderbilt University Medical Center | 12 | 2019-08-19 | 2020-03-10 |
| The Biobehavioral Impact of Diet Quality on Affect and Craving Dietary Change (low in highly processed foods) - Food Addiction, Withdrawal | Not applicable | Completed | University of Michigan | 68 | 2019-06-18 | 2021-11-01 |
| Opioid Physiology Project Tolerance, Withdrawal | Completed | University of Tennessee | 87 | 2017-08-14 | 2018-10-11 | |
| Evaluation of the Effect of Venous Diameter Measurement by Ultrasonography on Pain and Withdrawal Response Pain Score, Withdrawal movement score, hemodynamic response - Pain, Withdrawal | Completed | Aydin Adnan Menderes University | 145 | 2017-06-01 | 2017-12-19 | |
| Sublingual Buprenorphine Treatment for Neonatal Abstinence Syndrome - Pilot Study BZDs + opiate exposure treated with BPN, Opiates exposure treated with BPN - Drug; Withdrawal Symptoms, Neonatal, Withdrawal | Phase 1 / Phase 2 | Unknown | Gauda, Estelle B., M.D. | 40 | 2014-10-01 | 2016-05-06 |
| Terminal Weaning of Mechanical Ventilation or Extubation in Anticipation of Death in the Intensive Care Unit Withdrawal, Anxiety | Completed | Centre Hospitalier Departemental Vendee | 458 | 2013-04-01 | 2015-07-10 | |
| Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care: - Adenovirus, Anesthesia | Completed | Daniel Benjamin | 3520 | 2011-11-01 | 2023-09-06 |
Anxiety Disorders (2) · Heart Failure (2) · Pain (2) · Adenoviridae Infections (1) · Arrhythmias, Cardiac (1) · Arthritis, Psoriatic (1) · Autistic Disorder (1) · Behavior, Addictive (1) · Bipolar Disorder (1) · Bradycardia (1) · Central Nervous System Infections (1) · Cytomegalovirus Retinitis (1) · Death (1) · Depression (1) · Dyspnea (1)
Mental Disorders (6) · Behavior (4) · Pathological Conditions, Signs and Symptoms (4) · Chemically-Induced Disorders (3) · Signs and Symptoms (3) · Cardiovascular Diseases (2) · Compulsive Behavior (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Heart Diseases (2) · Impulsive Behavior (2) · Neurologic Manifestations (2) · Pathologic Processes (2) · Respiratory Tract Diseases (2) · Skin Diseases (2) · Skin and Connective Tissue Diseases (2)
Abatacept (1) · Acupuncture, Ear (1) · Adalimumab (1) · Alfentanil (1) · Amikacin (1) · Aminocaproic Acid (1) · Bosentan (1) · Buprenorphine (1) · Buprenorphine, Naloxone Drug Combination (1) · Cefepime (1) · Certolizumab Pegol (1) · Cidofovir (1) · Ciprofloxacin (1) · Clozapine (1) · Etanercept (1)
Aydin Adnan Menderes University (1) · Centre Hospitalier Departemental Vendee (1) · Daniel Benjamin (1) · Gauda, Estelle B., M.D. (1) · Johns Hopkins University (1) · Maimónides Biomedical Research Institute of Córdoba (1) · University Hospital, Montpellier (1) · University of Erlangen-Nürnberg Medical School (1) · University of Michigan (1) · University of Tennessee (1) · Vanderbilt University Medical Center (1)
United States (6) · France (2) · Canada (1) · Germany (1) · Israel (1) · Singapore (1) · Spain (1) · Turkey (Türkiye) (1) · United Kingdom (1)
Alberto Torres Zamudio, MD (1) · Ashley Gearhardt, Ph.D (1) · Chi Hornik, PharmD (1) · Estelle B Gauda, MD (1) · Heather Jackson, MSN (1) · Jean Reignier, MD, PhD (1) · Justin Strickland, Ph.D. (1) · Karen J Derefinko, PhD (1)
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R01DA057925 (1)