4 completed, 3 unknown, 2 terminated, 1 recruiting. 10 Phase 2, 4 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 10 | Completed 4, Unknown 3, Terminated 2, Recruiting 1 |
| Phase 3 | 4 | Terminated 2, Unknown 2 |
Follow Ventricular Remodeling: new trials by email Literature Review of Ventricular Remodeling trials Research Report on Ventricular Remodeling
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cardiovascular Effects of SGLT2 Inhibitors in Hemodialysis Patients: A Phase 2 Randomized Study iSGLT2 - Chronic Kidney Disease Requiring Hemodialysis | Phase 2 | Recruiting | Maximo Agustin Schiavone | 80 | 2025-05-01 | 2025-04-16 |
| Effect of Empagliflozin 10 vs 25 mg on LV Remodeling in Diabetic Patients With Anterior STEMI With Reduced LVEF Empagliflozin 10 MG [Jardiance], empagliflozin (Jardiance) 25 mg - Diabete Mellitus, Heart Failure | Phase 2 | Completed | Ain Shams University | 200 | 2023-07-12 | 2025-09-12 |
| COlchicine for Left VEntricular Remodeling Treatment in Acute Myocardial Infarction Colchicine group (experimental arm), Placebo group (control arm) - Myocardial Infarction | Phase 2 | Completed | Hospices Civils de Lyon | 194 | 2018-07-23 | 2025-08-01 |
| Effect of Methotrexate Carried by a Lipid Nanoemulsion on Left Ventricular Remodeling After STEMI Methotrexate, Placebo, Folic Acid - Myocardial Infarction, Anterior Wall, Myocardial Remodeling, Ventricular | Phase 2 / Phase 3 | Terminated | University of Sao Paulo | 35 | 2018-04-17 | 2021-01-11 |
| The Effect of Glucocorticoid Therapy on Left Ventricular Remodelling in Acute Myocardial Infarction (RECONSIDER) Hydrocortisone, Placebo - ST-segment Elevation Myocardial Infarction, Left Ventricular Remodeling | Phase 2 / Phase 3 | Unknown | Iuliu Hatieganu University of Medicine and Pharmacy | 77 | 2018-03-08 | 2020-09-28 |
| Personalised Prospective Comparison of ARni With ArB in Patients With Natriuretic Peptide eLEvation Sacubitril-Valsartan, Valsartan - Atrial Remodeling, Myocardial Dysfunction | Phase 2 | Unknown | Mark Ledwidge | 250 | 2015-12-16 | 2021-05-11 |
| Changes in Myocardial Biomechanics and Early Short-term Doxycycline Therapy in Patients With Primary Anterior STEMI Doxycycline, Standard care for STEMI - Vascular Diseases, Cardiovascular Diseases | Phase 2 / Phase 3 | Unknown | Russian Academy of Medical Sciences | 45 | 2014-02-01 | 2016-12-13 |
| Tetracycline (Doxycycline) and Post Myocardial Infarction Remodeling Doxycycline, Current medical therapy for AMI - Myocardial Infarction, Left Ventricular Remodeling | Phase 2 | Completed | Careggi Hospital | 110 | 2007-05-01 | 2012-09-25 |
| Cell Therapy in Myocardial Infarction Autologous Bone Marrow Mononuclear Cells (ABMMC) Transplantation - Acute Myocardial Infarction | Phase 2 / Phase 3 | Terminated | Ministry of Health, Brazil | 166 | 2006-07-01 | 2017-03-30 |
| REVEAL: Reduction of Infarct Expansion and Ventricular Remodeling With Erythropoietin After Large Myocardial Infarction Epoetin alfa - Acute ST Elevation Myocardial Infarction | Phase 2 | Completed | National Institute on Aging (NIA) | 223 | 2005-09-01 | 2017-05-09 |
Myocardial Infarction (3) · ST Elevation Myocardial Infarction (3) · Cardiovascular Diseases (2) · Anterior Wall Myocardial Infarction (1) · Atrial Remodeling (1) · Diabetes Mellitus (1) · Heart Failure (1) · Hypertension (1) · Inflammation (1) · Myocardial Ischemia (1) · Myocarditis (1) · Myositis (1) · Renal Insufficiency, Chronic (1) · Vascular Diseases (1)
Pathological Conditions, Anatomical (10) · Pathological Conditions, Signs and Symptoms (10) · Heart Diseases (8) · Pathologic Processes (8) · Cardiovascular Diseases (7) · Infarction (6) · Ischemia (6) · Necrosis (6) · Vascular Diseases (6) · Myocardial Ischemia (5) · Myocardial Infarction (3) · Cardiomyopathies (1) · Chronic Disease (1) · Disease Attributes (1) · Endocrine System Diseases (1)
Doxycycline (2) · Epoetin Alfa (1) · Folic Acid (1) · Hydrocortisone (1) · Methotrexate (1) · Sodium Chloride (1) · Sodium-Glucose Transporter 2 Inhibitors (1) · Standard of Care (1) · Transplantation (1) · Valsartan (1) · empagliflozin (1) · sacubitril and valsartan sodium hydrate drug combination (1)
Ain Shams University (1) · Careggi Hospital (1) · Hospices Civils de Lyon (1) · Iuliu Hatieganu University of Medicine and Pharmacy (1) · Mark Ledwidge (1) · Maximo Agustin Schiavone (1) · Ministry of Health, Brazil (1) · National Institute on Aging (NIA) (1) · Russian Academy of Medical Sciences (1) · University of Sao Paulo (1)
Brazil (2) · Argentina (1) · Egypt (1) · France (1) · Ireland (1) · Romania (1) · Russia (1) · United States (1)
Adrian Corneliu Iancu, M.D, Ph.D (1) · Alberto Santini, MD (1) · Aline G. Ferrari, MD (1) · Carlos E Castellaro, MD, MSc (1) · David Antoniucci, MD (1) · Edward G Lakatta, M.D. (1) · Emilio V Dovellini, MD (1) · Fiona Ryan, Co-Investigator, PhD (1) · Giampaolo Cerisano, MD (1) · Hans F Dohmann, MD (1) · Nazario Carrabba, MD (1) · Paolo D Pucci, MD (1) · Piergiovanni Buonamici, MD (1)
PMID 21095264, PMID 21558517, PMID 24104875, PMID 34420373, PMID 36884247, PMID 42349572
2015 (1), 2017 (1)