3 unknown, 2 completed, 2 not yet recruiting, 2 terminated. 10 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Unknown 3, Completed 2, Not yet recruiting 2, Terminated 2, Active not recruiting 1 |
| Phase 2 | 4 | Terminated 2, Unknown 2 |
Follow Ventricular Remodeling: new trials by email Literature Review of Ventricular Remodeling trials Research Report on Ventricular Remodeling
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Baxdrostat and Ventricular Remodeling Baxdrostat, Placebo - Cardiac Remodeling | Phase 3 | Not yet recruiting | Subodh Verma | 286 | 2026-06-30 | 2026-06-17 |
| Finerenone and Cardiac Remodeling Finerenone, Placebo - Heart Failure | Phase 3 | Not yet recruiting | Subodh Verma | 156 | 2025-12-01 | 2025-12-08 |
| Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19 Prednisolone, Losartan - COVID-19 Associated Cardiac Involvement, Remodeling, Left Ventricle | Phase 3 | Active not recruiting | Valentina Puentmann | 279 | 2022-12-12 | 2025-12-09 |
| MSCs for Prevention of MI-induced HF Umbilical Cord-Derived Wharton's Jelly Mesenchymal Stem Cells (WJ-MSCs), Conventional Treatment - Myocardial Infarction, Acute, Myocardial Infarction First | Phase 3 | Completed | Shiraz University of Medical Sciences | 420 | 2021-09-15 | 2024-11-04 |
| Effect of Doxycycline on Cardiac Remodelling in STEMI Patients Doxycycline 100Mg Capsule, Placebo oral capsule - ST Elevation Myocardial Infarction, Anterior Wall Myocardial Infarction | Phase 3 | Unknown | Felix Chikita Fredy, MD | 80 | 2019-05-25 | 2019-08-06 |
| Effect of Methotrexate Carried by a Lipid Nanoemulsion on Left Ventricular Remodeling After STEMI Methotrexate, Placebo, Folic Acid - Myocardial Infarction, Anterior Wall, Myocardial Remodeling, Ventricular | Phase 2 / Phase 3 | Terminated | University of Sao Paulo | 35 | 2018-04-17 | 2021-01-11 |
| The Effect of Glucocorticoid Therapy on Left Ventricular Remodelling in Acute Myocardial Infarction (RECONSIDER) Hydrocortisone, Placebo - ST-segment Elevation Myocardial Infarction, Left Ventricular Remodeling | Phase 2 / Phase 3 | Unknown | Iuliu Hatieganu University of Medicine and Pharmacy | 77 | 2018-03-08 | 2020-09-28 |
| Effect of Vitamin D on Ventricular Remodeling in Patients With Acute Myocardial Infarction (VITDAMI) Calcifediol, Placebo - Myocardial Infarction | Phase 3 | Completed | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | 109 | 2015-10-01 | 2023-10-03 |
| Changes in Myocardial Biomechanics and Early Short-term Doxycycline Therapy in Patients With Primary Anterior STEMI Doxycycline, Standard care for STEMI - Vascular Diseases, Cardiovascular Diseases | Phase 2 / Phase 3 | Unknown | Russian Academy of Medical Sciences | 45 | 2014-02-01 | 2016-12-13 |
| Cell Therapy in Myocardial Infarction Autologous Bone Marrow Mononuclear Cells (ABMMC) Transplantation - Acute Myocardial Infarction | Phase 2 / Phase 3 | Terminated | Ministry of Health, Brazil | 166 | 2006-07-01 | 2017-03-30 |
ST Elevation Myocardial Infarction (4) · Anterior Wall Myocardial Infarction (3) · Heart Failure (3) · Myocardial Infarction (3) · Cardiovascular Diseases (1) · Microvascular Angina (1) · Myocardial Ischemia (1) · Myocarditis (1) · Pericarditis (1) · Post-Acute COVID-19 Syndrome (1) · Vascular Diseases (1) · Vascular Remodeling (1) · Ventricular Dysfunction, Left (1)
Pathological Conditions, Anatomical (10) · Pathological Conditions, Signs and Symptoms (10) · Heart Diseases (9) · Cardiovascular Diseases (8) · Pathologic Processes (8) · Infarction (7) · Ischemia (7) · Myocardial Ischemia (7) · Necrosis (7) · Vascular Diseases (7) · Myocardial Infarction (4) · Angina Pectoris (1) · COVID-19 (1) · Cardiomyopathies (1) · Chronic Disease (1)
Doxycycline (2) · Calcifediol (1) · Folic Acid (1) · Hydrocortisone (1) · Losartan (1) · Methotrexate (1) · Prednisolone (1) · Sodium Chloride (1) · Standard of Care (1) · Transplantation (1) · Vitamin D (1) · finerenone (1)
Subodh Verma (2) · Felix Chikita Fredy, MD (1) · Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz (1) · Iuliu Hatieganu University of Medicine and Pharmacy (1) · Ministry of Health, Brazil (1) · Russian Academy of Medical Sciences (1) · Shiraz University of Medical Sciences (1) · University of Sao Paulo (1) · Valentina Puentmann (1)
Brazil (2) · Canada (2) · Austria (1) · Germany (1) · Indonesia (1) · Iran (1) · Romania (1) · Russia (1) · Spain (1)
Subodh Verma, MD, PhD (2) · Adrian Corneliu Iancu, M.D, Ph.D (1) · Aline G. Ferrari, MD (1) · Armin Attar, MD (1) · Bambang Widyantoro, PhD (1) · Eike Nagel, MD, PhD (1) · Hans F Dohmann, MD (1) · Valentina Puntmann, MD, PhD (1) · Vyacheslav Ryabov, MD,PhD (1)