64 completed, 26 unknown, 25 recruiting, 15 terminated. 99 Not applicable, 14 Phase 2, 7 Phase 3, 7 Phase 4, 5 Phase 1.
Follow Venous Leg Ulcer: new trials by email Literature Review of Venous Leg Ulcer trials Research Report on Venous Leg Ulcer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| LUT017 Gel for Venous Leg Ulcers and Chronic Non-Healing Skin Wounds in Adults LUT017 gel - Venous Leg Ulcer, Chronic Non-Healing Cutaneous Wounds | Phase 1 | Not yet recruiting | Antoni Ribas | 18 | 2026-10-02 | 2026-05-29 |
| The GORE® VIABAHN® FORTEGRA Venous Stent Post-Approval Study GORE® VIABAHN® FORTEGRA Venous Stent - Venous Thromboses, Venous Disease | Not applicable | Recruiting | W.L.Gore & Associates | 150 | 2026-08-25 | 2026-10-26 |
| Evaluating the Efficacy of NeoThelium FT in the Treatment of Venous Leg Ulcers Standard of Care, NeoThelium FT - Venous Leg Ulcer | Not applicable | Not yet recruiting | NuScience Medical Biologics, LLC | 132 | 2026-07-01 | 2026-04-13 |
| Evaluation of the Efficacy of Hyalomatrix® in the Healing of Chronic Venous Leg Ulcers Hyalomatrix, Standard of Care - Venous Leg Ulcer, Chronic Wounds | Not applicable | Recruiting | NuScience Medical Biologics, LLC | 122 | 2026-05-14 | 2026-06-30 |
| PAW-Hydrogel for Chronic Wound Healing PAW-Functionalized Carbopol® 940 Hydrogel, Standard Advanced Wound Care - Diabetic Foot Ulcer (DFU), Pressure Ulcer (PU) | Not applicable | Recruiting | Benjamín Gonzalo Rodríguez Méndez | 50 | 2026-04-20 | 2026-04-21 |
| Efficacy of Human Placental Membrane Products and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers Tri-Membrane Wrap™ DFU, Membrane Wrap™ DFU, Membrane Wrap-Lite™ DFU - Diabetic Foot Ulcer, Foot Ulcer Chronic | Not applicable | Recruiting | BioLab Holdings | 50 | 2026-01-02 | 2026-10-01 |
| Cold atmOspheric plaSMa Therapy Versus standArd Wound Care in Diabetic Foot and Venous Leg ulcerS COLD ATMOSPHERIC PLASMA - Diabetic Foot Ulcer, Venous Leg Ulcer | Not applicable | Not yet recruiting | Olaf Bakker | 494 | 2025-11-30 | 2025-11-26 |
| PMCF Study of Debridement Pad Debridement Pad - Diabetic Ulcers, Venous Leg Ulcer | Not applicable | Completed | Advanced Medical Solutions Ltd. | 184 | 2025-11-20 | 2026-07-08 |
| COMS for Chronic Ulcers Treatment Concurrent optical and magnetic stimulation (COMS) treatment - Venous Leg Ulcer, Wound Heal | Phase 4 | Recruiting | Sebastian Probst | 122 | 2025-10-01 | 2026-05-08 |
| CAMP RWE Trial: Amnion Grafts for Healing Hard-to-Heal Ulcers in RW Populations IP1: BioLab Membrane Wrap Lite IP2: BioLab Tri-Membrane Wrap, IP2: BioLab Tri-Membrane Wrap - Diabetic Foot Ulcer (DFU), Venous Leg Ulcer | Not applicable | Recruiting | Capsicure, LLC | 165 | 2025-10-01 | 2025-10-22 |
| Suprasorb®X+PHMB Pro vs Suprasorb®X+PHMB in Treatment of Infected Venous Leg Ulcers PHMB-impregnated biocellulose wound dressing with additional polyethylene film on top, compression therapy, systemic antomicrobial therapy (optional), PHMB-impregnated biocellulose wound dressing without additional polyethylene film on top, compression therapy, systemic antomicrobial therapy (optional) - Venous Leg Ulcer | Not applicable | Recruiting | Lohmann & Rauscher | 150 | 2025-09-23 | 2026-04-01 |
| Prospective Case Series Evaluating the Efficacy and Safety of NeoThelium FT for Venous Leg Ulcers NeoThelium FT (HCT/P 361) - Venous Leg Ulcer | Not applicable | Recruiting | NuScience Medical Biologics, LLC | 10 | 2025-09-02 | 2026-05-06 |
| Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers Standard of Care DFU, Tri-Membrane Wrap™ DFU, Membrane Wrap™ DFU - Diabetic Foot, DFU | Phase 4 | Recruiting | BioLab Holdings | 650 | 2025-07-15 | 2025-07-28 |
| AQUACEL® Ag+ Extra™ vs Cutimed® Sorbact® Venous Leg Ulcer, Diabetic Foot | Completed | ConvaTec Inc. | 105 | 2025-04-22 | 2026-01-08 | |
| Clinical Investigation of Sorbact® Dressings Sorbact® Compress, Sorbact® Gel Dressing, Sorbact® Ribbon Gauze - Hard-to-heal Wounds, Diabetic Foot Ulcer | Not applicable | Recruiting | ABIGO Medical AB | 30 | 2025-04-05 | 2026-09-14 |
| Tissue Repair Gel in Venous Leg Ulcers in AU/US TR987 0.1% gel + Standard of Care, Standard of care - Venous Leg Ulcer, Venous Ulcer | Phase 3 | Recruiting | TR Therapeutics | 312 | 2025-04-01 | 2025-04-02 |
| Human Amniotic Membrane On Venous Leg Ulcers In an Elderly Population Membrane Wrap™, Standard of Care - Venous Leg Ulcer | Not applicable | Terminated | BioLab Holdings | 30 | 2025-03-31 | 2026-05-27 |
| Non-healing Venous Leg Ulcers Treated With Standard Care With or Without BR-AC BR-AC, Standard Care - Non-infected Venous Leg Ulcer, Venous Leg Ulcer | Not applicable | Active not recruiting | BioStem Technologies | 71 | 2025-02-14 | 2026-09-29 |
| Tissue Repair Gel in Venous Leg Ulcers (US) TR987 0.1% gel + Standard of Care, Standard of care - Venous Leg Ulcer, Venous Ulcer | Phase 3 | Recruiting | TR Therapeutics | 312 | 2025-01-28 | 2026-02-12 |
| Evaluating the Durability of Closure for Venous Leg Ulcers Venous Leg, Venous Leg Ulcer (VLU) | Recruiting | Kerecis Ltd. | 150 | 2025-01-01 | 2025-01-24 |
Showing 20 of 150. Sign in to see all of them.
Varicose Ulcer (150) · Diabetic Foot (37) · Pressure Ulcer (16) · Leg Ulcer (15) · Wounds and Injuries (14) · Ulcer (11) · Venous Insufficiency (7) · Foot Ulcer (4) · Venous Thrombosis (4) · Burns (3) · Surgical Wound (3) · Varicose Veins (3) · Accidental Injuries (2) · Foot Injuries (2) · Gastroesophageal Reflux (2)
Cardiovascular Diseases (150) · Skin Diseases (150) · Skin and Connective Tissue Diseases (150) · Vascular Diseases (150) · Skin Ulcer (149) · Varicose Veins (147) · Leg Ulcer (135) · Diabetes Complications (37) · Diabetes Mellitus (37) · Diabetic Angiopathies (37) · Diabetic Neuropathies (37) · Endocrine System Diseases (37) · Foot Ulcer (33) · Pathological Conditions, Signs and Symptoms (18) · Pathologic Processes (16)
Standard of Care (13) · Gels (3) · Aspirin (2) · Polidocanol (2) · Therapeutics (2) · Bandages (1) · Compression Bandages (1) · Drug Implants (1) · Educational Status (1) · Electromagnetic Fields (1) · Exercise (1) · Hydrogels (1) · Lasers (1) · Levobupivacaine (1) · Lidocaine (1)
Molnlycke Health Care AB (7) · Firstkind Ltd (6) · Laboratoires URGO (5) · ConvaTec Inc. (4) · B. Braun Ltd. Centre of Excellence Infection Control (3) · BioLab Holdings (3) · Healthpoint (3) · NuScience Medical Biologics, LLC (3) · W.L.Gore & Associates (3) · Coloplast A/S (2) · Imperial College London (2) · KLOX Technologies Inc. (2) · Kerecis Ltd. (2) · Lohmann & Rauscher (2) · MediWound Ltd (2)
United States (70) · United Kingdom (21) · France (13) · Germany (11) · Canada (8) · Italy (8) · Poland (8) · Denmark (6) · Czechia (5) · Hungary (5) · Ireland (5) · Sweden (5) · Austria (4) · Spain (4) · Switzerland (4)
William Marston, MD (5) · Angelina Ferguson, DNP (2) · Hadar Lev-Tov, MD, MAS (2) · Herbert B Slade, MD (2) · Keith Harding, MD (2) · Koen Lim (2) · Kush Desai, MD (2) · Robert Kirsner, MD (2) · Agnes Collarte (1) · Aksone Nouvong, MD (1) · Alun Davies (1) · Amal Fawzy, Ph.D (1) · Andrew J Applewhite, MD,CWSP,FUHM (1)
PMID 26025146, PMID 10194512, PMID 10355863, PMID 10396491, PMID 11510598, PMID 15941430, PMID 16835515, PMID 17156107, PMID 20559172, PMID 21337794, PMID 21944912, PMID 22863328, PMID 25650040, PMID 26554558, PMID 26992340, PMID 26992985, PMID 27707417, PMID 28624002, PMID 29175902, PMID 30325305, PMID 30583949, PMID 30775606, PMID 31140402, PMID 31349862, PMID 31970660, PMID 32451241, PMID 32636985, PMID 32965493, PMID 33541436, PMID 34829797, PMID 35883458, PMID 36785909, PMID 37526355, PMID 38687339, PMID 39763591, PMID 39968829, PMID 40243046, PMID 40330756, PMID 41649921, PMID 41972998, PMID 42366370, PMID 42574339, PMID 7856198, PMID 8156326, PMID 9821029
R01AR073614 (1)