7 recruiting, 6 completed, 5 unknown. 6 Not applicable, 3 Phase 3, 2 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 2, Recruiting 2, Unknown 2 |
| Phase 3 | 3 | Completed 2, Recruiting 1 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
| Phase 4 | 1 | Unknown 1 |
Follow Vasospastic Angina: new trials by email Literature Review of Vasospastic Angina trials Research Report on Vasospastic Angina
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Invasive Evaluation and Phenotype-Guided Treatment of ANOCA in Women Invasive Coronary Functional and Morphological Assessment, Pharmacological treatment will be individualized according to the invasive coronary phenotype identified. Treatment may include antianginal therapy, vasodilator therapy, endothelial function-targeted - ANOCA - Angina With Non-obstructive Coronary Arteries, Coronary Microvascular Dysfunction (CMD) | Not applicable | Recruiting | Hospital de Clínicas Dr. Manuel Quintela | 50 | 2026-05-15 | 2026-11-04 |
| The Impact of Vericiguat on Microvascular Function in Patients With Documented Vasospastic Angina Pectoris Vericiguat - Vasospastic Angina | Phase 2 | Completed | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 57 | 2025-02-10 | 2026-07-29 |
| POLish Registry of CArdioneuroablation and CArdioneuromodulation cardioneuroablation, SN sparing hybrid ablation, Cardiac sympathetic denervation - Vasovagal Syndrome VVS, Cardioinhibitory Carotid Sinus Syndrome CSS | Recruiting | SABAMED Medical Center Ltd. | 1000 | 2024-11-21 | 2025-09-29 | |
| Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary Arteries Amlodipine, Nebivolol, Placebo - Angina Pectoris, Microvascular Angina | Phase 2 / Phase 3 | Recruiting | Stanford University | 150 | 2024-10-10 | 2024-11-27 |
| Transcutaneous Electrical Nerve Stimulation in Patients With Angina and Non-Obstructive Coronary Arteries Transcutaneous Electrical Nerve Stimulation - Microvascular Angina, Vasospastic Angina | Not applicable | Unknown | Catharina Ziekenhuis Eindhoven | 20 | 2024-03-13 | 2024-05-06 |
| Comprehensive Coronary Physiology in Patients With Angina With Nonobstructive Coronary Arteries - Czech Republic ANOCA, ANOCA - Angina With Non-obstructive Coronary Arteries | Recruiting | University Hospital, Motol | 1000 | 2023-04-20 | 2025-08-05 | |
| Randomized Trial to Examine a Differential Therapeutic Response in Symptomatic Patients With Non-obstructive Coronary Artery Disease Bisoprolol, Diltiazem, Placebo - Coronary Microvascular Dysfunction, Microvascular Angina | Phase 4 | Unknown | Charite University, Berlin, Germany | 132 | 2022-03-04 | 2022-03-24 |
| iCorMicA - Stratified Medicine in Angina Disclosure of IDP results, IDP performed but results not disclosed - Microvascular Angina, Angina, Stable | Not applicable | Recruiting | NHS Greater Glasgow and Clyde | 1500 | 2020-12-30 | 2026-04-09 |
| Coronary Microcirculatory Disease and Inflammation in Patients With Chronic Coronary Syndrome and no Significant Coronary Artery Stenosis Comprehensive functional diagnostics of coronary circulation - Coronary Artery Disease, Ischemia and No Obstructive Coronary Arteries | Unknown | Bartlomiej Guzik | 160 | 2020-07-24 | 2022-04-06 | |
| Immunomodulatory Therapy & VSA glucocorticosteroids and/or intravenous immunoglobulin - Vasospastic Angina | Completed | Dao Wen Wang | 71 | 2018-10-01 | 2024-11-20 | |
| Myocardial Ischemia Without Obstructive Coronary Stenoses Invasive coronary endothelium-dependent and non-endothelium-dependent physiological assessment - Myocardial Ischemia, Non-Obstructive Coronary Atherosclerosis | Recruiting | Hospital San Carlos, Madrid | 600 | 2017-11-08 | 2021-04-26 | |
| Multidetector Coronary CT In Vasospastic Angina Positive CAG with EG test, Negative CAG with EG test - Vasospastic Angina | Not applicable | Unknown | Dong-A University | 150 | 2014-04-01 | 2020-07-22 |
| Safety and Efficacy Study of Cilostazol to Treat Vasospastic Angina Cilostazol - Vasospastic Angina | Phase 3 | Completed | Korea Otsuka Pharmaceutical Co., Ltd. | 65 | 2013-12-01 | 2016-01-29 |
| A Therapeutic Confirmatory Study to Evaluate the Efficacy and Safety of Cilostazol in Subjects With Vasospastic Angina Cilostazol, placebo - Vasospastic Angina | Phase 3 | Completed | Korea Otsuka Pharmaceutical Co., Ltd. | 100 | 2013-11-01 | 2017-05-04 |
| Gangwon PCI Prospective Registry Percutaneous Coronary Intervention (PCI) - Coronary Artery Disease, Ischemic Heart Disease (IHD) | Recruiting | Yonsei University | 10000 | 2013-01-01 | 2026-10-07 | |
| A Multi-Omics Study of Vasospastic Angina Vasospastic Angina | Unknown | Tongji Hospital | 1200 | 2012-01-01 | 2022-03-16 | |
| Bioequivalency Study of Amlodipine Tablets Under Fasting Conditions Amlodipine - Hypertension, Chronic Stable Angina | Not applicable | Completed | Roxane Laboratories | 40 | 2004-04-01 | 2018-01-23 |
| Bioequivalency Study of Amlodipine Tablets Under Fed Conditions Amlodipine - Hypertension, Chronic Stable Angina | Not applicable | Completed | Roxane Laboratories | 40 | 2004-04-01 | 2018-01-23 |
Angina Pectoris, Variant (18) · Microvascular Angina (7) · Coronary Artery Disease (4) · Angina, Stable (3) · Myocardial Ischemia (3) · Angina Pectoris (2) · Hypertension (2) · Ischemia (2) · Angina, Unstable (1) · Autonomic Nervous System Diseases (1) · Coronary Vasospasm (1) · Hypotension, Orthostatic (1) · MINOCA (1) · Myocardial Bridging (1) · Non-ST Elevated Myocardial Infarction (1)
Cardiovascular Diseases (18) · Chest Pain (18) · Heart Diseases (18) · Neurologic Manifestations (18) · Pain (18) · Pathological Conditions, Signs and Symptoms (18) · Signs and Symptoms (18) · Vascular Diseases (18) · Angina, Unstable (17) · Angina Pectoris (16) · Myocardial Ischemia (15) · Arterial Occlusive Diseases (4) · Arteriosclerosis (4) · Coronary Disease (4) · Pathologic Processes (4)
Amlodipine (3) · Cilostazol (2) · Adrenergic beta-Antagonists (1) · Bisoprolol (1) · Diltiazem (1) · Nebivolol (1) · Percutaneous Coronary Intervention (1) · Transcutaneous Electric Nerve Stimulation (1) · vericiguat (1)
Korea Otsuka Pharmaceutical Co., Ltd. (2) · Roxane Laboratories (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Bartlomiej Guzik (1) · Catharina Ziekenhuis Eindhoven (1) · Charite University, Berlin, Germany (1) · Dao Wen Wang (1) · Dong-A University (1) · Hospital San Carlos, Madrid (1) · Hospital de Clínicas Dr. Manuel Quintela (1) · NHS Greater Glasgow and Clyde (1) · SABAMED Medical Center Ltd. (1) · Stanford University (1) · Tongji Hospital (1) · University Hospital, Motol (1)
South Korea (4) · Netherlands (3) · Poland (3) · United States (3) · China (2) · Czechia (1) · Germany (1) · Ireland (1) · Spain (1) · Switzerland (1) · United Kingdom (1) · Uruguay (1)
Colin Berry, MBChB, PhD (1) · Hernan Mejia-Renteria, MD, PhD (1) · Jacek Legutko, MD, PhD, Professor (1) · Javier Escaned, MD, PhD (1) · Jennifer Tremmel, MD (1) · Junghong Kim, MD (1) · Marta Kornaszewska, MD (1) · Moo Hyun Kim, M.D. (1) · Petr Kala, M.D., Ph.D. (1) · Sebastian Stec, Prof., MD, PhD (1) · Steven Herrmann, MD (1) · Ulf Landmesser, Prof. Dr. (1) · Walter Parham, MD (1)
PMID 16357399, PMID 19716193, PMID 22247633, PMID 23453453, PMID 25273915, PMID 36534493, PMID 36807273, PMID 39297854, PMID 39508144, PMID 39691038, PMID 40308206, PMID 41826400, PMID 42034271, PMID 42409349, PMID 42670734