22 completed, 3 active not recruiting, 2 unknown, 1 recruiting. 8 Not applicable, 7 Phase 2, 7 Phase 3, 5 Phase 1, 3 Phase 4.
Follow Vitamin K 1: new trials by email Literature Review of Vitamin K 1 trials Research Report on Vitamin K 1
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Role of Vitamin K on Knee Osteoarthritis Outcomes Vitamin K1 500 µg, K1 1000 µg, Vitamin K2 (MK-7) 300 µg - Osteo Arthritis Knee | Phase 1 / Phase 2 | Active not recruiting | Boston University | 49 | 2025-06-03 | 2026-09-21 |
| Effects of Vitamin K on Lower-extremity Function in Adults With Osteoarthritis: Vitamin K, Placebo - Osteo Arthritis Knee | Not applicable | Active not recruiting | Tufts University | 37 | 2023-09-20 | 2025-09-17 |
| Efficacy and Safety of Intravenous Vitamin K1 in Management of Acute Variceal Bleeding Vitamin K1 - Variceal Bleeding | Phase 4 | Completed | Zagazig University | 66 | 2022-10-03 | 2025-02-21 |
| A Study of BPM31510 With Vitamin K1 in Subjects With Newly Diagnosed Glioblastoma (GB) BPM31510, Vitamin K1, Temozolomide (TMZ) - Glioblastoma, Glioblastoma Multiforme | Phase 2 | Active not recruiting | BPGbio | 50 | 2022-08-22 | 2026-01-26 |
| A Pharmacokinetic Study to Evaluate the Drug Interaction Between SHR0302 and CYP Substrates in Healthy Volunteers SHR0302 Tablets, Midazolam Maleate Tablets, Warfarin Sodium Tablets - Rheumatoid Arthritis | Phase 1 | Completed | Jiangsu HengRui Medicine Co., Ltd. | 24 | 2022-07-15 | 2022-12-22 |
| A Pharmacokinetic Study to Evaluate the Drug Interaction Between HRS5091 and Probe Drugs in Healthy Volunteers HRS5091 Tablets, Midazolam Maleate Tablets, Warfarin Sodium Tablets - Chronic Hepatitis B | Phase 1 | Completed | Jiangsu HengRui Medicine Co., Ltd. | 22 | 2022-04-29 | 2022-12-23 |
| Better Evidence and Translation for Calciphylaxis Vitamin K1, Magnesium citrate, Sodium Thiosulfate - Calciphylaxis | Phase 3 | Recruiting | University of Sydney | 350 | 2021-08-26 | 2025-08-13 |
| Comparative Study Evaluating the Effect of Vitamin K1 Versus Vitamin K2 on Vascular Calcification in Dialysis Patients Vitamin K1, Vitamin k2, placebo - End Stage Renal Disease on Dialysis | Phase 2 / Phase 3 | Completed | Ain Shams University | 40 | 2020-07-25 | 2021-07-21 |
| Incorporation of Vitamin K Into Uremic Lipoproteins Vitamin K supplement - Vitamin K Deficiency | Not applicable | Completed | RWTH Aachen University | 20 | 2020-03-31 | 2022-05-04 |
| Late Vitamin K Deficiency-related Bleeding in Neonates (VKLB): Comparison of Different Strategies to Prophylaxis Konakion - Late Vitamin K Deficiency-related Bleeding | Completed | Azienda Ospedaliero-Universitaria di Parma | 80 | 2020-03-27 | 2023-02-06 | |
| Effect of Vitamin K in Critically Ill Patients Phytomenadione - Coagulation Factor Deficiency, Coagulopathy, Consumption | Completed | Region Skane | 52 | 2019-02-13 | 2021-03-18 | |
| Vitamin k1 and Its Relation to Vascular Calcification in Hemodialysis Patients oral vitamin k1 (phylloquinone) - Vascular Calcification | Phase 4 | Completed | Assiut University | 120 | 2018-01-01 | 2021-10-05 |
| Effects of Fhytomenadione on Coronary Artery Calcification of Hemodialysis Patients phytomenadione, placebo solution - Coronary Calcification | Not applicable | Completed | Instituto Mexicano del Seguro Social | 60 | 2017-09-07 | 2020-01-29 |
| Vitamin K1 in the Treatment of Spontaneous Intracerebral Hemorrhage Vitamin K 1, normal saline - Intracerebral Haemorrhage in Cerebellum | Early Phase 1 | Unknown | HUANG XIANJIAN | 400 | 2017-08-01 | 2018-01-04 |
| Management of Decompensated HCV Cirrhotic Patients Sofosbuvir 400mg (Sovaldi) + Daclatasvir 60 mg (Daklinza) + Ribavirin 200 mg (Rebetol), vitamin K (Phytomenadione) 10 mg+ furosemide and spironolactone (Lasilactone) 50 mg + milk thistle (Silymarin) 140 mg + Albumin infusion - Decompensated Cirrhosis | Not applicable | Completed | Zagazig University | 80 | 2015-06-01 | 2018-12-05 |
| Vitamin K as Additive Treatment in Osteoporosis Phylloquinone, Menatetrenone (MK4), placebo - Post-menopausal Osteoporosis | Phase 2 / Phase 3 | Unknown | Guy's and St Thomas' NHS Foundation Trust | 105 | 2015-04-01 | 2020-02-13 |
| Vitamin K Supplementation in Patients on Hemodialysis vitamin K1 - End Stage Renal Failure on Dialysis, Atrial Fibrillation | Phase 2 | Completed | University Health Network, Toronto | 3 | 2014-01-01 | 2018-02-06 |
| Vitamin K1 to Slow Progression of Vascular Calcification in HD Patients Vitamin K1 - Cardiovascular Diseases | Phase 3 | Terminated | RWTH Aachen University | 63 | 2013-10-01 | 2020-10-08 |
| Vitamin K to Attenuate Coronary Artery Calcification in Hemodialysis Patients Vitamin K1, Microcrystalline Methylcellulose - End-stage Kidney Disease | Phase 2 | Completed | Dr. Rachel Holden | 85 | 2012-11-01 | 2021-06-28 |
| Vitamin K2 Intervention in Patients With Vitamin K Antagonists Vitamin K2 - Thrombosis | Phase 2 | Completed | Danisco | 50 | 2012-02-01 | 2014-04-08 |
Showing 20 of 30. Sign in to see all of them.
Osteoporosis (4) · Thrombosis (3) · Osteoporosis, Postmenopausal (2) · Renal Insufficiency, Chronic (2) · Vascular Calcification (2) · Vitamin K Deficiency (2) · Arthritis, Rheumatoid (1) · Atrial Fibrillation (1) · Calciphylaxis (1) · Cardiovascular Diseases (1) · Crohn Disease (1) · Disseminated Intravascular Coagulation (1) · Embolism (1) · Esophageal and Gastric Varices (1) · Gastrointestinal Hemorrhage (1)
Jiangsu HengRui Medicine Co., Ltd. (2) · RWTH Aachen University (2) · Tufts University (2) · University Health Network, Toronto (2) · Zagazig University (2) · Ain Shams University (1) · Assiut University (1) · Azienda Ospedaliero-Universitaria di Parma (1) · BPGbio (1) · Bayer (1) · Boehringer Ingelheim (1) · Boston University (1) · Danisco (1) · Dr. Rachel Holden (1) · Guy's and St Thomas' NHS Foundation Trust (1)
United States (6) · Canada (4) · China (3) · Egypt (3) · Germany (3) · Sweden (2) · Australia (1) · Belgium (1) · France (1) · Ireland (1) · Israel (1) · Italy (1) · Mexico (1) · Netherlands (1) · New Zealand (1)
Amr S Hanafy, md (1) · Angela M Cheung, MD, PhD (1) · Ayman Sadek, MD (1) · Cees Vermeer, PhD (1) · Fergus Shanahan, Professor (1) · Geeta Hampson, MD (1) · Hilda E Macias Cervantes, Doctor (1) · Jean Liew, MD MS (1) · Kevin D Cashman, Professor (1) · Kirsti Tiihonen, PhD (1) · Ludovic Drouet, Professor (1)
PMID 15514282, PMID 18922041, PMID 20881072, PMID 22437558, PMID 24528331, PMID 25739929, PMID 26075081, PMID 26176325, PMID 30590596, PMID 30758786, PMID 31529295, PMID 35641194, PMID 37338608, PMID 37464978, PMID 37870112, PMID 39186385
2008 (1), K23AR082938 (1)