36 completed, 11 unknown, 4 recruiting, 4 withdrawn. 60 Phase 2, 13 Phase 1, 8 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 60 | Completed 36, Unknown 11, Recruiting 4, Withdrawn 4, Terminated 3, Not yet recruiting 2 |
| Phase 1 | 13 | Completed 5, Unknown 5, Terminated 2, Withdrawn 1 |
| Phase 3 | 8 | Completed 8 |
Follow Uterine Hemorrhage: new trials by email Literature Review of Uterine Hemorrhage trials Research Report on Uterine Hemorrhage
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| HMBeacon: A Phase 2 Study to Evaluate ALN-6400 in Adult and Adolescent Female Patients With VWD and HMB ALN-6400 - Von Willebrand Disease (VWD), Heavy Menstrual Bleeding (HMB) | Phase 2 | Recruiting | Alnylam Pharmaceuticals | 24 | 2026-07-30 | 2026-10-26 |
| Sublingual Oxytocin for the Prevention of Post-partum Hemorrhage Oxytocin sublingual, Oxytocin IM - Post Partum Hemorrhage | Phase 2 | Not yet recruiting | Insud Pharma | 330 | 2026-05-30 | 2026-04-23 |
| Role of Intravenous Calcium to Decrease Blood Loss During Intrapartum Cesarean Section Calcium Chloride, Placebo - Post Partum Haemorrhage, Cesarean Section Surgery | Phase 2 | Not yet recruiting | Pak Emirates Military Hospital | 182 | 2026-05-01 | 2026-04-24 |
| Transdermal Ethinyl Estradiol and Norelgestromin for Irregular Bleeding in Contraceptive Implant Users Transdermal Ethinyl Estradiol/Norelgestromin Patch, Placebo Patch - Menstruation Disturbances, Metrorrhagia | Phase 2 | Recruiting | Chulalongkorn University | 40 | 2025-07-29 | 2025-12-10 |
| Oxytocin Pharmacokinetics and Pharmacodynamics deuterated oxytocin (d5OT) - Post Partum Hemorrhage, Cesarean Section Complications | Phase 2 | Recruiting | Stanford University | 100 | 2025-01-01 | 2026-08-21 |
| High Or Low Dose pOstpartUm Oxytocin at the Time of Cesarean Birth Oxytocin - Postpartum Hemorrhage, Pregnancy Complications | Phase 2 | Withdrawn | University of Chicago | 2024-10-01 | 2024-12-10 | |
| D-chiro-inositol and AUB D-chiro-inositol and lactalbumin (high dose), D-chiro-inositol and lactalbumin (low dose) - Abnormal Uterine Bleeding | Phase 2 | Unknown | University Of Perugia | 20 | 2024-06-01 | 2024-05-03 |
| PAI-1, tPA, TFPI and HEECs in Uterine Hemostasis Sample Collection and Endometrial Biopsy - Menstrual Bleeding, Heavy | Phase 1 / Phase 2 | Unknown | Oregon Health and Science University | 70 | 2023-07-12 | 2024-08-19 |
| Efficacy of Carbetocin in Prevention of Postpartum Hemorrhage in Obese Versus Non Obese Women Carbetocin 100 Microgram/mL Solution for Injection - Obesity, Maternal, Post Partum Hemorrhage | Phase 1 / Phase 2 | Completed | Cairo University | 150 | 2023-07-06 | 2024-01-22 |
| Prevention of Postpartum Hemorrhage With Tranexamic Acid Tranexamic acid, No intervention - Post Partum Hemorrhage | Phase 2 | Recruiting | Inova Health Care Services | 120 | 2022-12-28 | 2026-10-16 |
| Failed Endometrial Ablation Treatment With Implantable Progesterone (FEAT) Study Etonogestrel 68mg implant - Abnormal Uterine Bleeding, Dysmenorrhea | Phase 2 | Withdrawn | Saskatchewan Health Authority - Regina Area | 2022-07-01 | 2025-11-25 | |
| Effect of Tranexamic Acid and Calcium Dobesilate for Bleeding of Endometrial Origin Tranexamic Acid, Calcium dobesilate (Doxium) - Heavy. Mentrual Bleeding, Abormal utèrine Bleeding | Phase 2 / Phase 3 | Completed | District Headquarters Teaching Hospital Sahiwal | 100 | 2022-01-01 | 2024-11-27 |
| Prevention of Primary Postpartum Haemorrhage Misoprostol, Oxytocin - Primary, Post Partum Hemorrhage | Phase 2 | Unknown | Islamabad Medical and Dental College | 180 | 2021-02-03 | 2021-02-25 |
| A Program to Evaluate Riastap® and FIBTEM® for the Early Control and Treatment of Postpartum Hemorrhage (PERFECT PPH) fibrinogen concentrate, Placebo - Postpartum Hemorrhage | Phase 1 / Phase 2 | Withdrawn | Yale University | 2021-01-01 | 2021-03-15 | |
| Chinese Medicine Periodic Therapy for Dysfunctional Uterine Bleeding During Adolescence With Yin Deficiency and Blood Heat Syndrome Kidney-tonifying and tune up Chong-Ren hemostasis Chinese medicine, Gong Xue Ning capsules - Dysfunctional Uterine Bleeding | Phase 2 | Completed | Children's Hospital of Fudan University | 160 | 2020-09-02 | 2022-08-03 |
| Tranexamic Acid Versus Sublingual Misoprostol in Reducing Blood Loss During Elective CS in High Risk Cases Misoprostol, Tranexamic acid, Oxytocin - Post Partum Hemorrhage | Phase 2 | Completed | Cairo University | 345 | 2020-01-20 | 2025-07-28 |
| Tranexamic Acid for the Prevention of Postpartum Haemorrhage Tranexamic Acid 100 milligram/Milliliter, Oxytocin - Postpartum Hemorrhage | Phase 1 / Phase 2 | Unknown | Benha University | 60 | 2020-01-01 | 2021-01-13 |
| Tranexamic Acid for Prevention of Hemorrhage in Cesarean Delivery Tranexamic Acid, Placebo - Post Partum Hemorrhage, Fibrinolysis; Hemorrhage | Phase 2 / Phase 3 | Completed | University of Texas Southwestern Medical Center | 110 | 2019-06-17 | 2021-01-19 |
| Intrauterine Misoprostol Versus Rectal Misoprostol in Reducing Blood Loss During Cesarean Section Misoprostol - Hemorrhage, Postpartum | Phase 2 | Unknown | Cairo University | 98 | 2018-11-15 | 2020-03-18 |
| Use of TXA to Prevent Postpartum Hemorrhage TXA (1g), Placebo (0.9% saline) - Post Partum Hemorrhage | Phase 2 | Unknown | Sunnybrook Health Sciences Centre | 31 | 2018-03-06 | 2022-09-13 |
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Postpartum Hemorrhage (34) · Menorrhagia (11) · Metrorrhagia (9) · Hemorrhage (6) · Leiomyoma (4) · Menstruation Disturbances (2) · Pain (2) · Thrombosis (2) · von Willebrand Diseases (2) · Adenomyosis (1) · Agranulocytosis (1) · Amenorrhea (1) · Anemia (1) · Anemia, Aplastic (1)
Female Urogenital Diseases and Pregnancy Complications (60) · Pathologic Processes (60) · Pathological Conditions, Signs and Symptoms (60) · Urogenital Diseases (60) · Hemorrhage (54) · Obstetric Labor Complications (34) · Puerperal Disorders (34) · Pregnancy Complications (33) · Female Urogenital Diseases (26) · Genital Diseases (26) · Genital Diseases, Female (26) · Uterine Diseases (26) · Menstruation Disturbances (12) · Hematologic Diseases (5)
Misoprostol (11) · Tranexamic Acid (10) · Oxytocin (9) · Norethindrone Acetate (3) · Sodium Chloride (3) · Estradiol (2) · Ethinyl Estradiol (2) · Fibrinogen (2) · Saline Solution (2) · carbetocin (2) · elagolix (2) · estradiol, norethindrone drug combination (2) · Anastrozole (1) · Arthotec (1) · Calcium Chloride (1)
Ain Shams University (4) · Ain Shams Maternity Hospital (3) · Cairo University (3) · Assiut University (2) · Bayer (2) · Benha University (2) · Chulalongkorn University (2) · McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. (2) · Qazvin University Of Medical Sciences (2) · AbbVie (1) · AbbVie (prior sponsor, Abbott) (1) · Aga Khan University (1) · Ahmed Alanwar (1) · Alnylam Pharmaceuticals (1) · AstraZeneca (1)
Egypt (14) · United States (12) · Iran (4) · Pakistan (4) · United Kingdom (4) · Italy (3) · Canada (2) · Germany (2) · Netherlands (2) · Sweden (2) · Thailand (2) · Austria (1) · Bangladesh (1) · Belgium (1) · Bulgaria (1)
Abubaker M Elnashar, MD (1) · Adel S Helal, MD (1) · Amgad E. Abou-Gamrah, Ass.Prof. (1) · Aminur Rahman, MBBS,MSc (1) · Amr Yehia, MD, MRCOG (1) · Anna Palatnik, MD (1) · Anne J. Wikkelsoe, MD (1) · Arash Afshari, MD (1) · Ariana Kh. Jawad, Assistant professor (1) · Ashish Premkumar, MD, PhD (1)
PMID 10467792, PMID 10908457, PMID 11502292, PMID 12466350, PMID 14600674, PMID 15932834, PMID 15950671, PMID 15954876, PMID 16581405, PMID 16842791, PMID 17197859, PMID 17634155, PMID 19432563, PMID 19943825, PMID 20009308, PMID 21833452, PMID 22540529, PMID 22805300, PMID 22882240, PMID 24220703, PMID 25586727, PMID 25588784, PMID 26181091, PMID 27733082, PMID 28707488, PMID 29025850, PMID 29524595, PMID 30303923, PMID 31022078, PMID 31598047, PMID 32559602, PMID 32609374, PMID 33064852, PMID 33248975, PMID 33384016, PMID 33705565, PMID 34218053, PMID 34858760, PMID 35038612, PMID 36934142, PMID 37626292
2009 (1), 2014 (1), 2025 (1), K23HL141640 (1), KL2TR001877 (1), R01HD110109 (1), UL1TR001876 (1)