12 completed, 6 unknown, 4 terminated, 2 withdrawn. 27 Phase 1, 13 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 27 | Completed 12, Unknown 6, Terminated 4, Withdrawn 2, Enrolling by invitation 1, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 13 | Completed 5, Unknown 5, Terminated 2, Withdrawn 1 |
Follow Uterine Hemorrhage: new trials by email Literature Review of Uterine Hemorrhage trials Research Report on Uterine Hemorrhage
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Combined Ketorolac and Lidocaine Paracervical Block for Office Hysteroscopy paracervical block, Lidocaine, ketorolac - Abnormal Uterine Bleeding, Analgesia | Phase 1 | Enrolling by invitation | Icahn School of Medicine at Mount Sinai | 60 | 2026-07-01 | 2026-10-22 |
| ROLE OF PROPHYLACTIC TRANEXAMIC ACID IN PREVENTION OF POST-PARTUM HEMORRHAGE IN ELLSCS Tranexamic Acid (TXA), Placebo - Post Partum Hemorrhage | Phase 1 | Not yet recruiting | Patel Hospital, Pakistan | 104 | 2025-06-01 | 2025-06-04 |
| Evaluation of Safety, Efficacy, and Pharmacokinetics of BT-114143 Injection in Patients With Abnormal Uterine Bleeding BT-114143 Injection at low dose, BT-114143 Injection at Medium-dose, BT-114143 Injection at High-dose - Abnormal Uterine Bleeding | Phase 1 | Recruiting | ScinnoHub Pharmaceutical Co., Ltd. | 39 | 2024-10-30 | 2025-12-15 |
| PAI-1, tPA, TFPI and HEECs in Uterine Hemostasis Sample Collection and Endometrial Biopsy - Menstrual Bleeding, Heavy | Phase 1 / Phase 2 | Unknown | Oregon Health and Science University | 70 | 2023-07-12 | 2024-08-19 |
| Efficacy of Carbetocin in Prevention of Postpartum Hemorrhage in Obese Versus Non Obese Women Carbetocin 100 Microgram/mL Solution for Injection - Obesity, Maternal, Post Partum Hemorrhage | Phase 1 / Phase 2 | Completed | Cairo University | 150 | 2023-07-06 | 2024-01-22 |
| A Study to Evaluate the Effect of Carbetocin on the QT/QTc Interval in Healthy Subjects Carbetocin, Placebo, Placebo and Moxifloxacin - Postpartum Hemorrhage | Phase 1 | Completed | Ferring Pharmaceuticals | 40 | 2023-05-25 | 2024-09-03 |
| Comparative Study Between the Roles of Intrauterine Misoprostol Versus the Sublingual Route for Prevention of Postpartum Blood Loss in Elective Cesarean Sections Misoprostol - Postpartum Hemorrhage | Phase 1 | Completed | Cairo University | 192 | 2022-01-01 | 2024-04-15 |
| A Program to Evaluate Riastap® and FIBTEM® for the Early Control and Treatment of Postpartum Hemorrhage (PERFECT PPH) fibrinogen concentrate, Placebo - Postpartum Hemorrhage | Phase 1 / Phase 2 | Withdrawn | Yale University | 2021-01-01 | 2021-03-15 | |
| Quality of Life Outcomes for Ulipristal Acetate and Tranexamic Acid in the Management of Heavy Menstrual Bleeding UPA, TEA, Placebo (for UPA) - Heavy Menstrual Bleeding | Phase 1 | Withdrawn | University of Saskatchewan | 2020-01-01 | 2020-01-28 | |
| Tranexamic Acid for the Prevention of Postpartum Haemorrhage Tranexamic Acid 100 milligram/Milliliter, Oxytocin - Postpartum Hemorrhage | Phase 1 / Phase 2 | Unknown | Benha University | 60 | 2020-01-01 | 2021-01-13 |
| COMPARISON OF A NEW FORMULATION OF GOSERELIN (Pepti 3.6 mg) to Zoladex® 3.6 mg Pepti 3.6 mg - Dysfunctional Uterine Bleeding | Phase 1 | Completed | Peptigroupe Inc. | 80 | 2018-10-29 | 2020-06-11 |
| Compare Efficacy of Oxytocin Administrations on Postpartum Uterine Contractility Oxytocin - Post Partum Haemorrhage | Phase 1 | Terminated | Oxytone Bioscience BV | 4 | 2018-04-03 | 2019-11-22 |
| Comparison of Inhaled Oxytocin (IH) With Intramuscular (IM) Oxytocin in Pregnant Women and With Intravenous (IV) Oxytocin in Healthy Non-pregnant Women IH Oxytocin, IM Oxytocin, IV Oxytocin - Postpartum Hemorrhage | Phase 1 | Terminated | GlaxoSmithKline | 31 | 2016-11-23 | 2020-03-23 |
| The Effect of Cyclofem® for the Treatment of Irregular Uterine Bleeding in Implant Contraceptive Users Cyclofem - Uterine Bleeding | Phase 1 / Phase 2 | Unknown | Chulalongkorn University | 44 | 2016-08-01 | 2017-08-30 |
| Tranexamic Acid and Ethamsylate For Preventing PPH in Patient Undergoing LSCS at High Risk For PPH Tranexamic Acid and Ethamsylate - Postpartum Hemorrhage | Phase 1 / Phase 2 | Unknown | Ahmed Alanwar | 64 | 2015-11-01 | 2015-11-30 |
| Safety, Tolerability and Pharmacokinetics (PK) Study of Oxytocin (GR121619) Administered Via an Inhaled Route in Healthy Female Volunteers IM oxytocin 10 IU, IH oxytocin 50 mcg, IH oxytocin 200 mcg - Postpartum Hemorrhage | Phase 1 | Completed | GlaxoSmithKline | 16 | 2015-09-14 | 2017-10-19 |
| Oral Tranexamic Acid Versus Diosmin for Treatment of Menorrhagia in Women Using Copper IUD Tranexamic Acid, Diosmin - Menorrhagia | Phase 1 / Phase 2 | Unknown | Ain Shams University | 100 | 2015-09-01 | 2015-11-30 |
| Tampostat for Management of Postpartum Hemorrhage Tampostat, Condom catheter tamponade - Postpartum Hemorrhage | Phase 1 / Phase 2 | Terminated | International Centre for Diarrhoeal Disease Research, Bangladesh | 344 | 2015-04-01 | 2018-11-26 |
| Prophylactic Use of Intraumbilical Vein Oxytocin Injection in The Management of Third Stage of Labor oxytocin, saline - Postpartum Hemorrhage | Phase 1 | Unknown | Ain Shams University | 1 | 2015-01-01 | 2016-03-02 |
| The Use of Levonorgestrel-Releasing Device (Metraplant-E) in the Treatment of Dysfunctional Uterine Bleeding Metraplant-E levonorgestrel-releasing intrauterine device - Dysfunctional Uterine Bleeding | Phase 1 / Phase 2 | Completed | Ain Shams Maternity Hospital | 61 | 2014-06-01 | 2016-03-14 |
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Postpartum Hemorrhage (15) · Metrorrhagia (6) · Menorrhagia (5) · Adenomyosis (1) · Agnosia (1) · Amenorrhea (1) · Anemia, Aplastic (1) · Dysmenorrhea (1) · Menstruation Disturbances (1) · Pain (1) · Pregnancy in Obesity (1) · Primary Ovarian Insufficiency (1) · Thrombocytopenia (1) · Thrombosis (1)
Female Urogenital Diseases and Pregnancy Complications (27) · Hemorrhage (27) · Pathologic Processes (27) · Pathological Conditions, Signs and Symptoms (27) · Urogenital Diseases (27) · Obstetric Labor Complications (15) · Pregnancy Complications (15) · Puerperal Disorders (15) · Female Urogenital Diseases (12) · Genital Diseases (12) · Genital Diseases, Female (12) · Uterine Diseases (12) · Menstruation Disturbances (5) · Signs and Symptoms (4)
Oxytocin (6) · Tranexamic Acid (4) · Misoprostol (3) · Control Groups (2) · Sodium Chloride (2) · Anesthesia, Obstetrical (1) · Bromocriptine (1) · CycloProvera (1) · Diosmin (1) · Ethamsylate (1) · Fibrinogen (1) · Goserelin (1) · Injections (1) · Ketorolac (1) · Lidocaine (1)
Ain Shams University (2) · Cairo University (2) · GlaxoSmithKline (2) · Qazvin University Of Medical Sciences (2) · Ahmed Alanwar (1) · Ain Shams Maternity Hospital (1) · Benha University (1) · Chulalongkorn University (1) · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) (1) · Ferring Pharmaceuticals (1) · Hormozgan University of Medical Sciences (1) · Icahn School of Medicine at Mount Sinai (1) · International Centre for Diarrhoeal Disease Research, Bangladesh (1) · Mansoura Integrated Fertility Center (1) · Mayo Clinic (1)
Egypt (7) · United States (5) · Iran (3) · United Kingdom (2) · Australia (1) · Bangladesh (1) · Canada (1) · China (1) · Japan (1) · Pakistan (1) · Sweden (1) · Thailand (1) · Ukraine (1)
Abubaker M Elnashar, MD (1) · Adel S Helal, MD (1) · Almereau Prollius, MD (1) · Aminur Rahman, MBBS,MSc (1) · Andrii Zaremba (1) · Charles Ascher-Walsh, MD (1) · Elizabeth Stewart, MD (1) · Michael J Paidas, MD (1) · Minoo Rajaei, Dr (1) · Mohamed Azzam, MD (1) · Nitisa Tapanwong, MD (1) · Pamela Stratton, MD (1)
PMID 10467792, PMID 10908457, PMID 11502292, PMID 14600674, PMID 15954876, PMID 16581405, PMID 16842791, PMID 17197859, PMID 17634155, PMID 19432563, PMID 19943825, PMID 20009308, PMID 22540529, PMID 22882240, PMID 24734184, PMID 28781129, PMID 31598047, PMID 32609374, PMID 37485589, PMID 37522415, PMID 39472831, PMID 42802704
2016 (1)