29 completed, 11 unknown, 3 recruiting, 2 terminated. 21 Not applicable, 12 Phase 4, 9 Phase 3, 3 Phase 2.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Efficacy and Mechanisms of a Topical Azone-Tranexamic Acid-Aloe Polysaccharide Gel in the Treatment of Melasma Ligustrazine - tranexamic acid - aloe polysaccharide composite gel - Melasma, Treatment of Stable Melasma | Not applicable | Not yet recruiting | The First Affiliated Hospital of Xinxiang Medical College | 10 | 2026-08-12 | 2026-04-14 |
| Effect of TXA on Reducing Bruising After Filler Injection Hyaluronic Acid (HA), Tranexamic Acid (TXA), Saline (placebo) - Facial Filler Injections, Hyaluronic Acid | Phase 2 | Recruiting | University of Wisconsin, Madison | 40 | 2025-12-05 | 2026-07-23 |
| BAR-TAX - Tranexamic Acid in Bariatric Surgery. Tranexamic Acid (TXA) - Bariatric Surgery, Bariatric Patients | Not applicable | Active not recruiting | Santa Maria Hospital - GVM Care & Research | 1000 | 2025-12-01 | 2026-02-12 |
| Efficacy and Safety of Tranexamic Acid in Adult Liver Transplantation---ESTA Trial tranexamic acid, 0.9 % saline - Liver Transplantation, Tranexamic Acid | Not applicable | Recruiting | RenJi Hospital | 1546 | 2025-11-01 | 2025-12-08 |
| Tranexamic Acid : Nebulization vs IV Route for Hemoptysis Tranexamic Acid (TXA) - Hemoptysis, NEBULIZATION | Phase 2 / Phase 3 | Completed | University of Health Sciences Lahore | 172 | 2025-08-01 | 2025-11-28 |
| Preoperative Tranexamic Acid (TXA) to Prevent Bleeding in Patients Undergoing Major Colorectal Surgery Tranexamic acid - Bleeding, Colorectal Disorders | Phase 2 | Recruiting | Kristen Ban | 394 | 2025-02-11 | 2026-05-28 |
| Comparing Intramyometrial Tranexamic Acid and Oxytocin for Blood Loss in Cesarean Section Tranexamic acid injection, Oxytocin - Cesarean Section Complications, Tranexamic Acid | Phase 3 | Unknown | Cairo University | 150 | 2024-10-01 | 2024-09-05 |
| Effect of Tranexamic Acid on Bleeding After Bariatric Surgery Morbid Obesity, Perioperative Hemorrhage | Completed | G.Gennimatas General Hospital | 140 | 2024-05-01 | 2026-08-10 | |
| Comparative Study of Tranexamic Acid, Estrogen for Treatment AUB in DMPA Users Tranexamic acid 250 mg oral tablet, Progynova 1 mg oral tablet - Abnormal Uterine Bleeding, Tranexamic Acid | Not applicable | Unknown | Department of Medical Services Ministry of Public Health of Thailand | 52 | 2023-09-30 | 2023-11-18 |
| Impact of Inhaled Tranexamic Acid in Pulmonary Hemorrhage in Pediatric Intensive Care Unit Tranexamic acid + conventional therapy., Tranexamic acid - Tranexamic Acid, Pulmonary Hemorrhage | Not applicable | Completed | Tanta University | 100 | 2023-08-01 | 2026-03-19 |
| Do Anesthesiologists Follow Guidelines on Perioperative Use of Tranexamic Acid? Use of tranexamic acid - Tranexamic Acid, Blood Loss, Surgical | Completed | Erasme University Hospital | 1726 | 2023-07-03 | 2023-08-30 | |
| Intraprostatic Injection of Tranexamic Acid Decrease Blood Loss During Monopolar TURP Tranexamic Acid group, Distilled water group - Benign Prostatic Hyperplasia, Transurethral Resection of the Prostate | Not applicable | Unknown | Benha University | 60 | 2023-06-20 | 2023-06-22 |
| Tranexamic Acid Injection With Different Drainage Clamping Time After Anterior Cruciate Ligament Reconstruction Tranexamic Acid Powder - Anterior Cruciate Ligament Reconstruction, Tranexamic Acid | Not applicable | Completed | Taipei Veterans General Hospital, Taiwan | 150 | 2022-09-05 | 2024-02-28 |
| Tranexamic Acid for Alloplastic Breast Reconstruction Tranexamic acid, Normal Saline - Hematoma Postoperative, Breast Cancer | Phase 3 | Unknown | McMaster University | 106 | 2022-08-01 | 2022-04-06 |
| Topical Tranexamic Acid for Bilateral Breast Reduction Surgery Tranexamic acid, Normal Saline - Hematoma Postoperative, Tranexamic Acid | Phase 3 | Unknown | McMaster University | 106 | 2022-08-01 | 2022-04-06 |
| Assessment of the Impact of Perioperative Administration of Tranexamic Acid on Bleeding After Sleeve Gastrectomy Administration of 1g tranexamic acid intravenous bolus, after anesthesia was introduced - Hemorrhage, Surgical, Bariatric Surgery | Not applicable | Completed | Medical University of Gdansk | 300 | 2022-07-04 | 2023-09-22 |
| Intravenous Tranexamic Acid Reducing Intraoperative Blood Loss in Huge Meningiomas Resection Continous infusion, Single infusion, Placebo - Tranexamic Acid, Intraoperative Blood Loss | Not applicable | Unknown | Beijing Tiantan Hospital | 228 | 2022-06-15 | 2022-08-29 |
| Effectiveness Of Tranexamic Acıd Application Wıth Different Doses On Bleeding, Edema And Physician Comfort In Orthognathıc Surgery Patients Tranexamic acid injection, Saline - Tranexamic Acid, Orthognathic Surgery | Not applicable | Completed | Bezmialem Vakif University | 60 | 2022-03-01 | 2024-03-08 |
| Arthroscopic Rotator Cuff Repair Performed With Intraarticular Tranexamic Acid Could it Provide Improved Visual Clarity and Less Post-operative Pain? A Prospective, Double Blind, Randomized Study of 64 Patients. Application of Tranexamic acid in arthroscopic irrigation solution, No application of Tranexamic acid in arthroscopic irrigation solution - Rotator Cuff Tears, Rotator Cuff Rupture | Not applicable | Completed | Florence Nightingale Hospital, Istanbul | 63 | 2022-01-01 | 2022-07-12 |
| Tranexamic Acid Dosage for Topical Treatment of Anterior Epistaxis Tranexamic acid, Saline - Anterior Epistaxis, Tranexamic Acid | Phase 4 | Completed | Izmir Ataturk Training and Research Hospital | 152 | 2021-12-16 | 2023-12-28 |
Showing 20 of 48. Sign in to see all of them.
Hemorrhage (12) · Blood Loss, Surgical (6) · Postpartum Hemorrhage (4) · Burns (3) · Postoperative Hemorrhage (3) · Wounds and Injuries (3) · Obesity, Morbid (2) · Rotator Cuff Injuries (2) · Thromboembolism (2) · Breast Neoplasms (1) · Edema (1) · Emergencies (1) · End Stage Liver Disease (1) · Epistaxis (1) · Fractures, Bone (1)
Pathologic Processes (26) · Pathological Conditions, Signs and Symptoms (26) · Hemorrhage (14) · Intraoperative Complications (6) · Urogenital Diseases (6) · Female Urogenital Diseases and Pregnancy Complications (5) · Signs and Symptoms (5) · Uterine Hemorrhage (5) · Wounds and Injuries (5) · Cardiovascular Diseases (4) · Embolism and Thrombosis (4) · Obstetric Labor Complications (4) · Pregnancy Complications (4) · Puerperal Disorders (4) · Vascular Diseases (4)
Tranexamic Acid (34) · Saline Solution (8) · Sodium Chloride (8) · Administration, Topical (1) · Anesthesia, General (1) · Estradiol (1) · Hyaluronic Acid (1) · Misoprostol (1) · Oxytocin (1) · Tablets (1)
Cairo University (2) · Corewell Health West (2) · McMaster University (2) · Amphia Hospital (1) · Beijing Jishuitan Hospital (1) · Beijing Tiantan Hospital (1) · Benha University (1) · Bezmialem Vakif University (1) · Bursa Yuksek Ihtisas Training and Research Hospital (1) · CUF Santarém Hospital (1) · Centre Hospitalier Saint Joseph Saint Luc de Lyon (1) · Chinese Academy of Medical Sciences, Fuwai Hospital (1) · Department of Medical Services Ministry of Public Health of Thailand (1) · Erasme University Hospital (1) · Florence Nightingale Hospital, Istanbul (1)
United States (7) · China (5) · Turkey (Türkiye) (5) · Canada (4) · Egypt (3) · Netherlands (2) · Taiwan (2) · Belgium (1) · Brazil (1) · Denmark (1) · France (1) · Greece (1) · India (1) · Iraq (1) · Israel (1)
Ahmed N Afifi, MD (1) · Ahmed N Shaker, MD (1) · Amalia Douma, PHD (1) · Angela Sa, MD (1) · Antonio Braun, MD (1) · Christopher Coroneos, MD, FRCSC (1) · Chro S. Hassan, MBChB (1) · Daniel Cho, MD, PhD (1) · Elizabeth Steensma, MD (1) · En-Rung Chiang (1) · Gerald P Wright, MD (1) · Gregory Cvetanovich, MD (1) · Gurleen Kaur, MD (1) · Kristen A Ban, MD MS (1)
PMID 18042876, PMID 18440953, PMID 21918164, PMID 22704676, PMID 25098850, PMID 26337246, PMID 26524933, PMID 26559015, PMID 26985786, PMID 28448319, PMID 28505683, PMID 28633147, PMID 28692467, PMID 28902659, PMID 30233155, PMID 30322584, PMID 30611343, PMID 31080025, PMID 31962259, PMID 34910219, PMID 36410494, PMID 37651373, PMID 38788904, PMID 39095919, PMID 40735345, PMID 42115323, PMID 9354828