112 completed. 112 Phase 3, 11 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 112 | Completed 112 |
| Phase 2 | 11 | Completed 11 |
Follow Thromboembolism: new trials by email Literature Review of Thromboembolism trials Research Report on Thromboembolism
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dimolegin® (60 mg) Given Once Daily in Patients Undergoing Total Hip or Knee Replacement Compared to Enoxaparin Sodium enoxaparin, Dimolegin, Dimolegin placebo - Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee | Phase 3 | Completed | Avexima Diol LLC | 215 | 2024-07-22 | 2026-01-16 |
| Tirofiban for Reduction of Thromboembolic Events in Endovascular Unruptured Aneurysm Repair Tirofiban, aspirin, clopidogrel - Unruptured Intracranial Aneurysm, Flow Diverter | Phase 2 / Phase 3 | Completed | Beijing Tiantan Hospital | 192 | 2024-03-04 | 2025-12-11 |
| TINzaparin Prophylaxis in Patients With Metastatic Colorectal Cancer Tinzaparin - Colorectal Cancer Metastatic, Thromboembolism | Phase 3 | Completed | Galician Research Group on Digestive Tumors | 232 | 2023-03-02 | 2025-08-22 |
| Postpartum Heparin Against Venous Thromboembolism: a Pilot Randomized Controlled Trial Enoxaparin - Venous Thromboembolism | Phase 3 | Completed | University Hospital, Geneva | 77 | 2022-05-03 | 2023-05-26 |
| Clinical Trial of Dimolegin (DD217) in Prevention of Thrombotic Complications in Patients With COVID-19 Dimolegin, Clexane - COVID-19, Venous Thromboembolism | Phase 3 | Completed | PharmaDiall Ltd. | 399 | 2021-02-08 | 2022-01-11 |
| VTE Prevention Following Total Hip and Knee Arthroplasty Rivaroxaban 10 MG and acetylsalicylic acid 81 mg, acetylsalicylic acid 81 mg - Venous Thromboembolism | Phase 3 | Completed | Sudeep Shivakumar | 5429 | 2021-02-04 | 2026-06-16 |
| Rivaroxaban Plus Aspirin to Manage Recurrent Venous Thromboembolic Events Rivaroxaban 20 MG [Xarelto], Aspirin 300mg, Acenocoumarol Oral Tablet - Venous Thromboembolism, Anticoagulant-induced Bleeding | Phase 2 / Phase 3 | Completed | Instituto Mexicano del Seguro Social | 58 | 2021-01-03 | 2022-08-25 |
| Medically Ill Hospitalized Patients for COVID-19 THrombosis Extended ProphyLaxis With Rivaroxaban ThErapy: The MICHELLE Trial Rivaroxaban 10 MG - Covid19, Venous Thromboembolism | Phase 3 | Completed | Science Valley Research Institute | 320 | 2020-10-16 | 2022-04-06 |
| A Pragmatic Randomized Controlled Trial of Therapeutic Anticoagulation Versus Standard Care as a Rapid Response to (SARS-CoV-2) COVID-19 Pandemic Therapeutic anticoagulation - COVID, Coronavirus Infection | Phase 3 | Completed | University of Sao Paulo General Hospital | 465 | 2020-07-04 | 2021-10-26 |
| Alteplase Compared to Tenecteplase in Patients With Acute Ischemic Stroke Tenecteplase, Alteplase - Stroke, Acute, Thromboses, Intracranial | Phase 3 | Completed | University of Calgary | 1600 | 2019-12-10 | 2023-05-12 |
| REduced Dose Versus Full-dose of Direct Oral Anticoagulant After uNprOvoked Venous thromboEmbolism. Reduced dose of DOAC, Full dose of DOAC - Venous Thromboembolism | Phase 3 | Completed | University Hospital, Brest | 2774 | 2017-11-02 | 2023-12-28 |
| Rivaroxaban vs. Warfarin in CVT Treatment Rivaroxaban, Warfarin - Cerebral Vein Thrombosis | Phase 3 | Completed | Damascus University | 71 | 2017-09-01 | 2023-02-16 |
| Apixaban in Preventing Secondary Cancer Related Venous Thrombosis in Cancer Patients Who Have Completed Anticoagulation Therapy Apixaban - Cerebral Vein Thrombosis, Deep Vein Thrombosis | Phase 3 | Completed | Academic and Community Cancer Research United | 370 | 2017-07-14 | 2025-05-18 |
| PREVENTion of Clot in Orthopaedic Trauma Acetylsalicylic acid, Low Molecular Weight Heparin (LMWH) - Blood Clot, Trauma | Phase 3 | Completed | Major Extremity Trauma Research Consortium | 12424 | 2017-04-24 | 2024-05-14 |
| Apixaban for the Treatment of Venous Thromboembolism in Patients With Cancer Apixaban, Dalteparin - Venous Thromboembolism | Phase 3 | Completed | Fadoi Foundation, Italy | 1170 | 2017-04-13 | 2025-06-24 |
| Hokusai Study in Pediatric Patients With Confirmed Venous Thromboembolism (VTE) Edoxaban, Standard of Care - Venous Thromboembolism (VTE), Pulmonary Embolism | Phase 3 | Completed | Daiichi Sankyo | 290 | 2017-03-27 | 2025-02-28 |
| A Clinical Trial Comparing Efficacy and Safety of Dabigatran Etexilate With Warfarin in Patients With Cerebral Venous and Dural Sinus Thrombosis (RE-SPECT CVT) Dabigatran etexilate, Warfarin - Thromboembolism | Phase 3 | Completed | Boehringer Ingelheim | 120 | 2016-12-13 | 2019-08-15 |
| Pharmacokinetic, Pharmacodynamic, Safety, and Efficacy Study of Rivaroxaban for Thromboprophylaxis in Pediatric Participants 2 to 8 Years of Age After the Fontan Procedure Rivaroxaban, Acetylsalicylic Acid - Thrombosis | Phase 3 | Completed | Janssen Research & Development, LLC | 112 | 2016-11-16 | 2025-03-30 |
| RAMBLE - Rivaroxaban vs. Apixaban for Heavy Menstrual Bleeding Apixaban, Rivaroxaban - Venous Thromboembolism, Menstruation | Phase 2 / Phase 3 | Completed | Indiana University | 19 | 2016-09-01 | 2023-11-13 |
| Cancer Associated Thrombosis, a Pilot Treatment Study Using Rivaroxaban rivaroxaban, Low-molecular-weight heparin - Neoplasm, Venous Thromboembolism | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 159 | 2016-09-01 | 2018-08-13 |
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Venous Thromboembolism (80) · Venous Thrombosis (26) · Pulmonary Embolism (24) · Thrombosis (14) · Hemorrhage (7) · Neoplasms (7) · Stroke (7) · Atrial Fibrillation (4) · Intracranial Thrombosis (4) · Cardiovascular Diseases (3) · Embolism (3) · Heart Diseases (3) · Neoplasm Metastasis (3) · Acute Coronary Syndrome (2)
Vascular Diseases (111) · Embolism and Thrombosis (110) · Cardiovascular Diseases (109) · Respiratory Tract Diseases (28) · Lung Diseases (26) · Embolism (24) · Pathological Conditions, Signs and Symptoms (21) · Pathologic Processes (20) · Thrombosis (20) · Brain Diseases (11) · Central Nervous System Diseases (11) · Nervous System Diseases (11) · Cerebrovascular Disorders (8) · Heart Diseases (6)
Enoxaparin (30) · Rivaroxaban (24) · Warfarin (14) · Dabigatran (11) · enoxaparin sodium (9) · Fondaparinux (8) · Heparin, Low-Molecular-Weight (8) · Dalteparin (7) · edoxaban (7) · AVE 5026 (6) · Aspirin (6) · apixaban (5) · Heparin (4) · Nadroparin (3) · Standard of Care (3)
Bayer (12) · Boehringer Ingelheim (11) · Sanofi (9) · GlaxoSmithKline (7) · Astellas Pharma Inc (6) · Daiichi Sankyo Co., Ltd. (4) · University Hospital, Brest (4) · Crux Biomedical (3) · Daiichi Sankyo (3) · Janssen Research & Development, LLC (3) · Academic and Community Cancer Research United (2) · McMaster University (2) · Ottawa Hospital Research Institute (2) · Washington University School of Medicine (2) · ARCA Biopharma, Inc. (1)
United States (50) · Canada (42) · Italy (31) · France (30) · Germany (29) · Spain (29) · Russia (28) · Denmark (27) · Czechia (26) · Netherlands (25) · Poland (25) · Australia (24) · Belgium (24) · Brazil (24) · South Africa (24)
Takeshi Fuji (3) · Alexander Turpie, MD (2) · Francis Couturaud, MD, PhD (2) · Giancarlo Agnelli, MD (2) · Jim Julian, MMath (2) · William D. Fisher, MD (2) · Agnes Y. Y. Lee, MD, MSc, FRCPC (1) · Ajay Kakkar, Prof., MD, PhD (1)
PMID 24081972, PMID 22429800, PMID 22709460, PMID 27807306, PMID 32657973, PMID 33337539, PMID 22995531, PMID 23425163, PMID 24344086, PMID 26578849, PMID 27980462, PMID 28617144, PMID 28762617, PMID 31975354, PMID 34755519, PMID 35389229, PMID 36150047, PMID 38348778, PMID 38844941, PMID 40163217, PMID 16537663, PMID 16537725, PMID 16926353, PMID 17723125, PMID 17869635, PMID 18042917, PMID 18402906, PMID 18579811, PMID 18579812, PMID 18582928, PMID 19411100, PMID 19721013, PMID 19726226, PMID 19825809, PMID 19854398, PMID 19966341, PMID 20047905, PMID 20124123, PMID 20448094, PMID 21128814, PMID 21225098, PMID 21315215, PMID 21359646, PMID 21505722, PMID 21791091, PMID 21861537, PMID 22013950, PMID 22168590, PMID 22284935, PMID 22335737
2014 (5), 2005 (3), 2015 (3), 2004 (2), 2008 (1), 2009 (1), 2016 (1), P30CA015083 (1), R01HL033233 (1), R01HL057951 (1), R01HL097036 (1), R42HL086316 (1), U01HL052193 (1), U01HL073958 (1), U01HL074815 (1)