74 completed, 18 terminated, 7 recruiting, 7 unknown. 112 Phase 2, 20 Phase 3, 8 Phase 1.
Follow Thromboembolism: new trials by email Literature Review of Thromboembolism trials Research Report on Thromboembolism
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Vortosiran for VTE Prevention Vortosiran, Placebo - Venous Thromboembolism (VTE), Cancer | Phase 2 | Not yet recruiting | Ribocure Pharmaceuticals AB | 150 | 2026-10-01 | 2026-09-30 |
| A Study to Compare the Efficacy and Safety of SRSD107 and Enoxaparin in Adult Subjects Undergoing TKA SRSD107, enoxaparin - Venous Thromboembolism | Phase 2 | Recruiting | Sirius Therapeutics Co., Ltd. | 450 | 2025-09-16 | 2026-01-15 |
| A Single-arm, Phase II Clinical Trial of ASPIRin to prEvent Venous Thromboembolism in Patients With Advanced Germ Cell Tumors Receiving Chemotherapy Low-dose ASA - Germ Cell Tumor, Testicular Cancer | Phase 2 | Recruiting | Wake Forest University Health Sciences | 35 | 2025-08-28 | 2026-07-24 |
| Preoperative Tranexamic Acid (TXA) to Prevent Bleeding in Patients Undergoing Major Colorectal Surgery Tranexamic acid - Bleeding, Colorectal Disorders | Phase 2 | Recruiting | Kristen Ban | 394 | 2025-02-11 | 2026-05-28 |
| Anti-Xa Guided Dosing of Low Molecular Weight Heparin for Prevention of Venous Thromboembolism Following Traumatic Injury: a Multicentre Pilot Randomized Trial Anti-Xa Guided Dosing of Low Molecular Weight Heparin, Standard of Care Dosing - Venous Thromboembolism (VTE), Trauma Related Injuries | Phase 2 / Phase 3 | Unknown | Alexandre Tran | 150 | 2025-01-01 | 2024-10-28 |
| VTE Prevention With Rivaroxaban in Genitourinary Cancer Patients Receiving Systemic Therapy Rivaroxaban 10 MG, Placebo control - Venous Thromboembolism, Urologic Cancer | Phase 2 / Phase 3 | Recruiting | Ottawa Hospital Research Institute | 120 | 2024-11-04 | 2025-07-10 |
| A Trial to Learn How Well REGN9933 and REGN7508 Work for Preventing Blood Clots, and How Safe They Are, in Adults Who Have a Peripherally Inserted Central Catheter (PICC) REGN9933, REGN7508, Placebo - Venous Thromboembolism | Phase 2 | Completed | Regeneron Pharmaceuticals | 195 | 2024-09-20 | 2026-04-13 |
| A Trial to Learn How Well REGN7508 Works for Preventing Blood Clots After a Knee Replacement in Adult Participants REGN7508, Enoxaparin - Venous Thromboembolism | Phase 2 | Completed | Regeneron Pharmaceuticals | 179 | 2024-06-27 | 2026-05-27 |
| Tirofiban for Reduction of Thromboembolic Events in Endovascular Unruptured Aneurysm Repair Tirofiban, aspirin, clopidogrel - Unruptured Intracranial Aneurysm, Flow Diverter | Phase 2 / Phase 3 | Completed | Beijing Tiantan Hospital | 192 | 2024-03-04 | 2025-12-11 |
| Low Molecular Weight Heparin or no Treatment Following Cesarean Delivery Enoxaparin - Thromboembolism | Phase 2 | Completed | University of Utah | 64 | 2023-10-11 | 2025-09-04 |
| Antithrombin to Improve Thromboprophylaxis and Reduce the Incidence of Trauma-Related Venous Thromboembolism Thrombate infusion, Placebo - Trauma Injury, Thromboembolism | Phase 2 | Enrolling by invitation | Bryan Cotton | 314 | 2023-09-27 | 2026-10-09 |
| A Trial to Learn How Well REGN9933 Works for Preventing Blood Clots After Knee Replacement Surgery in Adult Participants REGN9933, Enoxaparin, Apixiban - Venous Thromboembolism | Phase 2 | Completed | Regeneron Pharmaceuticals | 373 | 2023-05-24 | 2025-08-29 |
| Venous Thromboembolism Prevention in Outpatients With Glioma Apixaban - Glioblastoma, Astrocytoma | Phase 2 | Recruiting | University of Vermont Medical Center | 40 | 2023-01-16 | 2026-01-30 |
| Catheter-Related Early Thromboprophylaxis With Enoxaparin Studies Enoxaparin - Deep Venous Thrombosis | Phase 2 / Phase 3 | Recruiting | Yale University | 258 | 2022-05-11 | 2026-06-08 |
| Causes and Prevention of Thromboembolic Disease in Nephrotic Syndrome Dalteparin, Apixaban - Nephrotic Syndrome, Thromboembolic Disease | Phase 1 / Phase 2 | Completed | University of Aarhus | 57 | 2021-03-25 | 2025-04-11 |
| Optimal Dosing For Low-Dose Aspirin Chemoprophylaxis For VTE Following Total Joint Arthroplasty Aspirin - Venous Thromboembolism | Phase 2 | Recruiting | University of Miami | 5478 | 2021-03-01 | 2026-03-11 |
| Assessing Feasibility of Thromboprophylaxis With Apixaban in JAK2-positive Myeloproliferative Neoplasm Patients Apixaban 2.5 MG Oral Tablet [ELIQUIS], Aspirin 81 mg - Myeloproliferative Neoplasm (MPN), Essential Thrombocythemia (ET) | Phase 2 | Completed | Ottawa Hospital Research Institute | 44 | 2021-02-17 | 2024-05-29 |
| Rivaroxaban Plus Aspirin to Manage Recurrent Venous Thromboembolic Events Rivaroxaban 20 MG [Xarelto], Aspirin 300mg, Acenocoumarol Oral Tablet - Venous Thromboembolism, Anticoagulant-induced Bleeding | Phase 2 / Phase 3 | Completed | Instituto Mexicano del Seguro Social | 58 | 2021-01-03 | 2022-08-25 |
| Effect of Anticoagulation Therapy on Clinical Outcomes in COVID-19 Rivaroxaban, Standard Of Care (SOC) - COVID-19 | Phase 2 | Terminated | Charite University, Berlin, Germany | 111 | 2020-11-30 | 2022-01-12 |
| Apixaban vs Enoxaparin Following Microsurgical Breast Reconstruction-An RCT Apixaban 2.5 MG Oral Tablet, Enoxaparin 40Mg/0.4mL Prefilled Syringe - Venous Thromboembolism | Phase 1 / Phase 2 | Completed | Stanford University | 82 | 2020-08-12 | 2025-06-22 |
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Venous Thromboembolism (83) · Venous Thrombosis (24) · Pulmonary Embolism (16) · Atrial Fibrillation (7) · Neoplasms (7) · Thrombosis (7) · Hemorrhage (5) · Stroke (4) · Intracranial Embolism (3) · Intracranial Thrombosis (3) · Wounds and Injuries (3) · Carotid Stenosis (2) · Critical Illness (2) · Embolism and Thrombosis (2)
Cardiovascular Diseases (112) · Vascular Diseases (112) · Embolism and Thrombosis (110) · Thrombosis (22) · Pathological Conditions, Signs and Symptoms (20) · Pathologic Processes (18) · Embolism (16) · Lung Diseases (16) · Respiratory Tract Diseases (16) · Neoplasms (12) · Central Nervous System Diseases (11) · Nervous System Diseases (11) · Brain Diseases (10) · Cerebrovascular Disorders (10)
Enoxaparin (33) · Rivaroxaban (16) · apixaban (13) · Aspirin (11) · Dalteparin (10) · Warfarin (10) · Dabigatran (7) · Tinzaparin (4) · Heparin (3) · Heparin, Low-Molecular-Weight (3) · Rosuvastatin Calcium (3) · Tablets (3) · edoxaban (3) · Clopidogrel (2) · Fondaparinux (2)
Bayer (8) · Boehringer Ingelheim (8) · Ottawa Hospital Research Institute (7) · Astellas Pharma Inc (6) · University of Utah (5) · Daiichi Sankyo (3) · GlaxoSmithKline (3) · McMaster University (3) · Regeneron Pharmaceuticals (3) · Daiichi Sankyo Co., Ltd. (2) · Hamilton Health Sciences Corporation (2) · Sanofi (2) · Wake Forest University Health Sciences (2) · Yale University (2) · Alexandre Tran (1)
United States (43) · Canada (31) · Poland (18) · Russia (15) · Denmark (13) · Italy (13) · France (12) · Germany (12) · Norway (12) · Austria (11) · Israel (11) · Spain (11) · United Kingdom (11) · Bulgaria (10) · Czechia (10)
Christopher Puccini, MD (3) · Marc Carrier, MD (2) · Sam Schulman, MD, PhD (2) · Akihiko Taguchi, MD.PhD (1) · Alexandre Tran, MD, MSc, FRCSC (1) · Alissa A Thomas, MD (1) · Anders Gabrielsen, MD, PhD (1) · Ann Bruno, MD (1) · Anna Matyjek, MD, PhD (1)
PMID 33086312, PMID 31420317, PMID 33337539, PMID 41218619, PMID 18088349, PMID 18402906, PMID 18621928, PMID 19187076, PMID 19640572, PMID 19854398, PMID 20448094, PMID 20886185, PMID 21700934, PMID 22100906, PMID 22284935, PMID 22340437, PMID 22431865, PMID 22621626, PMID 23991661, PMID 24136153, PMID 24232703, PMID 24641937, PMID 24837794, PMID 25047458, PMID 25482425, PMID 26490434, PMID 26688233, PMID 27075710, PMID 27357738, PMID 29452956, PMID 29649055, PMID 30511879, PMID 30957581, PMID 31324209, PMID 31935028, PMID 32045583, PMID 32421159, PMID 32589230, PMID 32641236, PMID 32827160, PMID 33029262, PMID 33372745, PMID 33502773, PMID 33566465, PMID 33857789, PMID 34622445, PMID 34884411, PMID 35124234, PMID 35244208, PMID 35344784
2014 (3), 2016 (2), 2023 (2), 2005 (1), 2008 (1), 2009 (1), 2015 (1), 2017 (1), 2018 (1), P30CA015704 (1), R01HD106326 (1), R21HD089131 (1), R42HL086316 (1)