16 completed, 4 recruiting, 2 not yet recruiting, 2 unknown. 26 Phase 1, 9 Phase 2.
Follow Tetanus: new trials by email Literature Review of Tetanus trials Research Report on Tetanus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lm-LLO-TT and Gemcitabine in Unresectable Pancreatic Ductal Adenocarcinoma Lm-LLO-TT - Pancreas Cancer, Duct Cell Adenocarcinoma, Pancreatic Cancer | Phase 1 | Recruiting | Loki Therapeutics, Inc. | 18 | 2026-10-15 | 2026-11-06 |
| A Phase I/II Clinical Trial of the Diphtheria, Tetanus, Acellular Component Pertussis and Sabin Inactivated Poliomyelitis Vaccine Adsorbed Diphtheria, Tetanus, Acellular Component Pertussis and Sabin Inactivated Poliomyelitis Vaccine Adsorbed, Diphtheria, Tetanus and Acellular Component Pertussis Combined Vaccine, Diphtheria, Tetanus and Acellular Component Pertussis Combined Vaccine+Inactivated Poliomyelitis Vaccine Made From Sabin Strains - Diphtheria, Pertussis | Phase 1 / Phase 2 | Recruiting | Institute of Medical Biology, Chinese Academy of Medical Sciences | 380 | 2026-10-11 | 2026-10-23 |
| Phase I Clinical Trial of Adsorbed Tetanus Vaccine Tetanus Vaccine, Adsorbed - Tetanus | Phase 1 | Active not recruiting | Aimei Vacin BioPharm (Zhejiang) Co., Ltd. | 80 | 2026-05-21 | 2026-09-22 |
| A Phase I Clinical Trial of Absorbed Acellular Pertussis (Two-Component) Diphtheria-Tetanus Combined Vaccine (For Adults and Adolescents) Tdap vaccine - Pertussis (Whooping Cough), Diphtheria | Phase 1 | Not yet recruiting | Changchun BCHT Biotechnology Co. | 96 | 2026-04-20 | 2026-03-25 |
| Phase I/II Clinical Trial of Diphtheria-Tetanus-Pertussis (Reduced Dose) Vaccine low-dose Tetanus, Diphtheria and Acellular Component Pertussis Vaccine Adsorbed (Reduced Antigens Content), high-dose Tetanus, Diphtheria and Acellular Component Pertussis Vaccine Adsorbed (Reduced Antigens Content), Tetanus, Diphtheria and Acellular Pertussis Vaccine - Tetanus, Diphtheria and Acellular Pertussis Vaccination, Tetanus | Phase 1 / Phase 2 | Not yet recruiting | Institute of Medical Biology, Chinese Academy of Medical Sciences | 660 | 2026-03-12 | 2026-02-18 |
| Clinical Trial of the Adsorbed Acellular Pertussis (Tricomponent) DTaP-Haemophilus Influenzae Type b (Conjugate)-ACYW135 Group Meningococcal (Conjugate) Combined Vaccine Adsorbed Acellular Pertussis (3-Component) Diphtheria-Tetanus-Pertussis-Haemophilus influenzae type b (Conjugate)-Meningococcal Group ACYW135 (Conjugate) Combined Vaccine (DTcP-Hib-MCV4), DTcP-Hib-MCV4, Adsorbed Acellular Pertussis (3-Component) Diphtheria-Tetanus-Pertussis (DTcP) - Diphtheria, Tetanus and Acellular Pertussis, Epidemic Meningitis | Phase 1 | Recruiting | CanSino Biologics Inc. | 260 | 2025-12-19 | 2025-12-31 |
| Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Recombinant Human Anti-Tetanus Toxin Monoclonal Antibody Injection Recombinant Human Anti-Tetanus Toxin Monoclonal Antibody Injection, Human Tetanus Immunoglobulin, Placebo - Tetanus | Phase 1 | Enrolling by invitation | Lanzhou Institute of Biological Products Co., Ltd | 68 | 2025-08-18 | 2026-01-28 |
| Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SNA02-48 Injection in Chinese Adult Participants SNA02-48, Placebo, HTIG - Tetanus | Phase 1 / Phase 2 | Completed | Sinovac Life Sciences Co., Ltd. | 255 | 2025-04-28 | 2026-06-03 |
| Phase I Clinical Trial of Diphtheria-Tetanus-acellular Pertussis Component Combined Vaccine DTacP (one-dose booster), DTacP (three-dose primary vaccination), DT (one-dose booster) - Diphtheria, Tetanus | Phase 1 | Recruiting | Institute of Medical Biology, Chinese Academy of Medical Sciences | 460 | 2023-12-23 | 2024-01-03 |
| A Study to Evaluate the Safety and Immunogenicity of a Single Dose of Adsorbed Tetanus Vaccine in a Population Aged 18 Years and Over TTVA, TT - Tetanus | Phase 1 | Completed | CanSino Biologics Inc. | 60 | 2023-12-20 | 2024-11-29 |
| A Clinical Trial of Adsorbed Cell-free DPT Vaccine (5-component) (for People Aged 6 Years and Above) Tetanus, Reduced Diphtheria and Acellular Pertussis (Five Components) Combined Vaccine, Adsorbed (Aged 6 Years and Older) (Tdcp), 23-Valent Pneumococcal Polysaccharide Vaccine（PPV23）, Diphtheria and Tetanus Combined Vaccine, Adsorbed (DT) - Diphtheria, Tetanus | Phase 1 | Completed | CanSino Biologics Inc. | 180 | 2023-12-06 | 2026-08-07 |
| A Study to Evaluate Safety and Immunogenicity of APV006 in Healthy Adults DTaP-HepB-IPV-Hib vaccine - Diphtheria, Tetanus | Phase 1 | Unknown | LG Chem | 42 | 2023-07-17 | 2023-07-19 |
| Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Immunogenicity of GR2001 in Chinese Healthy Adults GR2001, Placebo, HTIG - Tetanus | Phase 1 / Phase 2 | Completed | Genrix (Shanghai) Biopharmaceutical Co., Ltd. | 202 | 2023-03-04 | 2024-03-08 |
| A Randomized, Open-Label, Parallel-Design Pharmacokinetic and Pharmacodynamic Interaction Study of TNM002 and Adsorbed Tetanus Vaccine TNM002, Adsorbed tetanus vaccine, TNM002 + adsorbed tetanus vaccine - Tetanus | Phase 1 | Completed | Zhuhai Trinomab Pharmaceutical Co., Ltd. | 60 | 2022-08-13 | 2024-09-23 |
| Phase I Clinical Trial of Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed . Diphtheria,Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed, Diphtheria and Tetanus Combined Vaccine, Adsorbed, Diphtheria-tetanus-acellular pertussis vaccine - Diphtheria, Tetanus | Phase 1 | Completed | CanSino Biologics Inc. | 400 | 2020-04-28 | 2022-10-31 |
| A Study to Compare LBVD to Eupenta and Imovax Polio in Healthy Adults DTP-HepB-IPV-Hib vaccine, DTP-HepB-Hib vaccine & IPV - Diphtheria, Tetanus | Phase 1 | Completed | LG Chem | 42 | 2017-07-03 | 2019-08-29 |
| A Study of AV0328 Administered to Healthy Adult Volunteers AV0328 - Cohort 1, AV0328 - Cohort 2, AV0328 - Cohort 3 - PNAG-expressing Pathogenic Microbes Vaccine | Phase 1 / Phase 2 | Completed | Alopexx Vaccine, LLC | 16 | 2017-03-22 | 2019-03-19 |
| Intrathecal Tetanus Immunoglobulin to Treat Tetanus Human tetanus immunoglobulin, Intramuscular antitoxin - Tetanus | Phase 1 / Phase 2 | Completed | Oxford University Clinical Research Unit, Vietnam | 272 | 2017-02-13 | 2020-05-29 |
| Safety and Efficacy of Two Tetanus-Diphtheria Vaccines for a Donor Hyper Immunization Program Tetanus and Diphtheria (Td) Vaccine - Healthy | Phase 1 | Completed | Biomat USA, Inc. | 300 | 2016-08-22 | 2021-07-20 |
| Safety and Immunogenicity Study of Tetanus, Diphtheria and Acellular Pertussis (Tdap) Vaccine Biological: GC3111 vaccine, Biological: Boostrix® vaccine - Tetanus, Diphtheria | Phase 1 / Phase 2 | Unknown | Green Cross Corporation | 220 | 2016-06-01 | 2016-11-07 |
Showing 20 of 26. Sign in to see all of them.
Diphtheria (15) · Whooping Cough (14) · Haemophilus Infections (3) · Poliomyelitis (3) · Hepatitis B (2) · Infections (1) · Meningitis, Meningococcal (1) · Otitis Media (1) · Pancreatic Neoplasms (1) · Trismus (1)
Bacterial Infections (26) · Bacterial Infections and Mycoses (26) · Clostridium Infections (26) · Gram-Positive Bacterial Infections (26) · Infections (25) · Actinomycetales Infections (15) · Corynebacterium Infections (15) · Gram-Negative Bacterial Infections (15) · Bordetella Infections (14) · Respiratory Tract Diseases (14) · Respiratory Tract Infections (14) · Nervous System Diseases (5) · Central Nervous System Diseases (4) · Central Nervous System Infections (4) · Neuroinflammatory Diseases (4)
Tetanus Toxoid (12) · Vaccines, Combined (3) · Diphtheria-Tetanus-acellular Pertussis Vaccines (2) · Saline Solution (2) · adacel (2) · 23-valent pneumococcal capsular polysaccharide vaccine (1) · Aging (1) · Boostrix (1) · Drug Evaluation (1) · Immunization, Secondary (1) · Pentavac (1) · Poliovirus Vaccine, Inactivated (1) · Sodium Chloride (1) · Vaccines (1) · ompP2 protein, Haemophilus influenzae (1)
CanSino Biologics Inc. (4) · Institute of Medical Biology, Chinese Academy of Medical Sciences (3) · Sanofi Pasteur, a Sanofi Company (3) · LG Chem (2) · Aimei Vacin BioPharm (Zhejiang) Co., Ltd. (1) · Alopexx Vaccine, LLC (1) · Biomat USA, Inc. (1) · Changchun BCHT Biotechnology Co. (1) · Genrix (Shanghai) Biopharmaceutical Co., Ltd. (1) · Green Cross Corporation (1) · Lanzhou Institute of Biological Products Co., Ltd (1) · Loki Therapeutics, Inc. (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · National Institute on Deafness and Other Communication Disorders (NIDCD) (1) · Novartis Vaccines (1)
China (13) · United States (6) · South Korea (2) · Belgium (1) · Japan (1) · Vietnam (1)
Geert Leroux-Roels, Prof. Dr. (1) · Hal Landy, MD (1) · Jianchang He (1) · Jiawei Xu (1) · Jie Hou, Doctor (1) · Jing Zhang, PHD (1) · Marilyn Rosa-Bray, MD (1) · Minh Yen Lam, MD (1) · Nam Joong Kim (1) · Shiguang Lei (1) · WJ Kim (1) · Wang Yanxia (1) · Wei Hu (1)
PMID 24794369, PMID 29172945, PMID 30809591, PMID 35561721, PMID 40977696