15 completed, 1 active not recruiting, 1 recruiting, 1 terminated. 11 Phase 3, 4 Phase 4, 2 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 11 | Completed 10, Active not recruiting 1 |
| Phase 4 | 4 | Completed 3, Terminated 1 |
| Phase 1 | 2 | Completed 1, Recruiting 1 |
| Phase 2 | 2 | Completed 2 |
Follow Pentavac: new trials by email Literature Review of Pentavac trials Research Report on Pentavac
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase I Clinical Trial of Diphtheria-Tetanus-acellular Pertussis Component Combined Vaccine DTacP (one-dose booster), DTacP (three-dose primary vaccination), DT (one-dose booster) - Diphtheria, Tetanus | Phase 1 | Recruiting | Institute of Medical Biology, Chinese Academy of Medical Sciences | 460 | 2023-12-23 | 2024-01-03 |
| A Phase 3 Study of BIBP Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed Diphtheria,Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed, Diphtheria,Tetanus and Acellular Pertussis Combined Vaccine, Adsorbed, Diphtheria,tetanus,pertussis(acellular,component),poliomyelitis(inactivated) vaccine(absorbed) and Haemophilus influenzae type b conjugate vaccine - Whooping Cough, Diphtheria | Phase 3 | Active not recruiting | China National Biotec Group Company Limited | 2898 | 2021-10-22 | 2025-09-15 |
| Safety and Immunogenicity of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the Russian Federation and Mexico Meningococcal Polysaccharide (Serogroups A, C, Y, and W) Tetanus Toxoid Conjugate Vaccine, Meningococcal (Groups A, C, Y and W 135) Oligosaccharide Diphtheria CRM197 Conjugate Vaccine, Measles, Mumps, and Rubella Virus Vaccine Live - Healthy Volunteers (Meningococcal Infection) | Phase 3 | Completed | Sanofi Pasteur, a Sanofi Company | 525 | 2018-10-17 | 2023-10-19 |
| Study Comparing DTP-HB-Hib by Disposable-Syringe Jet Injector To Vaccination By Needle And Syringe In Infants DTP-HB-Hib vaccine, Disposable Syringe Jet Injector (DSJI), Needle & Syringe - Immune Response to DTP-HB-Hib Vaccine | Phase 4 | Terminated | Serum Institute of India Pvt. Ltd. | 211 | 2015-01-01 | 2018-09-11 |
| Dose-Finding Study of S.Pneumoniae Whole Cell Vaccine Adsorbed to Alum (PATH-wSP) in Healthy Kenyan Adults and Toddlers PATH-wSP, Synflorix, Pentavac - Pneumonia, Pneumococcal | Phase 1 / Phase 2 | Completed | PATH | 304 | 2014-04-01 | 2019-10-10 |
| DTaP-IPV-Hep B-PRP~T Combined Vaccine Versus DTaP-IPV//PRP~T Combined Vaccine + Hep B Vaccine in Hep B Primed Infants DTaP-IPV-Hep B-PRP~T combined vaccine, DTaP-IPV//PRP~T and Hepatitis B vaccine - Diphtheria, Tetanus | Phase 3 | Completed | Sanofi Pasteur, a Sanofi Company | 310 | 2014-03-01 | 2017-04-26 |
| Safety of PENTAXIM® Given as a Three-Dose Primary Vaccination at 2, 3, and 4 Months of Age in Infants in China DTacP IPV//PRP~T combined vaccine: PENTAXIM® - Diphtheria, Tetanus | Phase 4 | Completed | Sanofi Pasteur, a Sanofi Company | 900 | 2011-12-01 | 2013-03-29 |
| Study of a Booster Injection of Pentaxim™ Vaccine Administered With Dengue Vaccine in Healthy Toddlers Live, attenuated, recombinant dengue serotype 1, 2, 3, and 4 virus, DTaP IPV//Hib vaccine, Placebo - Dengue, Dengue Hemorrhagic Fever | Phase 3 | Completed | Sanofi Pasteur, a Sanofi Company | 720 | 2011-07-18 | 2022-03-25 |
| Study of PENTAXIM™ Vaccine Versus TETRAXIM™ Vaccine Given With ACTHIB™ Vaccine in South Korean Infants. PENTAXIM™: DTacP IPV//PRP~T combined vaccine, TETRAXIM™: DTacP IPV combined vaccine and ActHIB™: PRP tetanus conjugate vaccine - Diphtheria, Tetanus | Phase 3 | Completed | Sanofi | 370 | 2010-09-01 | 2012-04-17 |
| Immunogenicity and Safety of Pentaxim as 3 Doses Primary Vaccination Followed by a Booster Dose at 18 Months Diphtheria, Tetanus, Polio, Acellular Pertussis and Hib, Diphtheria, Tetanus, & Acellular Pertussis Combined, Absorbed - Diphtheria, Tetanus | Phase 3 | Completed | Sanofi | 792 | 2007-03-01 | 2012-04-17 |
| Study to Evaluate a 13-valent Pneumococcal Conjugate Vaccine in Infants 13-valent pneumococcal conjugate vaccine, 7-valent pneumococcal conjugate vaccine, Pentavac - Vaccines, Pneumococcal | Phase 3 | Completed | Wyeth is now a wholly owned subsidiary of Pfizer | 613 | 2006-10-01 | 2012-08-15 |
| Immunogenicity of DTaP-IPV-Hep B-PRP~T Combined Vaccine Compared With PENTAXIM™ and ENGERIX B® at 2-3-4 Months Schedule DTaP-IPV-HB-PRP~T vaccine, DTaP-IPV//PRP~T combined, Hepatitis B vaccine - Hepatitis B, Polio | Phase 3 | Completed | Sanofi Pasteur, a Sanofi Company | 310 | 2006-07-01 | 2014-09-12 |
| Immunogenicity Study of Antibody Persistence and Booster Effect of PENTAXIM™ at 18 Months in Healthy Argentinean Infants DTaP-IPV//PRP~T combined vaccine - Diphtheria, Tetanus | Phase 3 | Completed | Sanofi | 458 | 2006-02-01 | 2013-02-22 |
| Immunogenicity and Safety of Pentaxim™ in an Indian Population Diphteria/Tetanus/Polio/Acellular Pertussis/Hib vaccine - Diphtheria, Tetanus | Phase 3 | Completed | Sanofi | 226 | 2006-02-01 | 2012-04-16 |
| Immunogenicity and Safety of Sanofi Pasteur Pentaxim Combined Vaccine in Infants in Thailand Diphtheria, Tetanus, Polio, Acellular Pertussis and Hib Vac - Diphtheria, Tetanus | Phase 4 | Completed | Sanofi | 186 | 2005-12-01 | 2012-04-16 |
| Immunogenicity and Safety of Pentaxim in South African Infants Diphtheria, Tetanus, Polio, Acellular Pertussis and Hib - Diphtheria, Tetanus | Phase 3 | Completed | Sanofi | 212 | 2005-10-01 | 2012-04-17 |
| Study of DTaP-IPV-Hep B-PRP~T Combined Vaccine Compared With PENTAXIM™ and ENGERIX B® PEDIATRICO in Argentinean Infants DTaP-IPV-HB-PRP~T, DTaP-IPV//PRP~T combined vaccine & Recombinant hep B vaccine - Diphtheria, Tetanus | Phase 2 | Completed | Sanofi Pasteur, a Sanofi Company | 624 | 2004-10-01 | 2013-12-17 |
| Assessment of the Immunogenicity and Safety of PENTAXIM™ in Philippines Diphteria, Tetanus, Polio, Acellular Pertussis, Hib vaccine - Diphtheria, Tetanus | Phase 4 | Completed | Sanofi | 387 | 2003-10-01 | 2012-04-16 |
Diphtheria (13) · Whooping Cough (13) · Tetanus (12) · Poliomyelitis (11) · Haemophilus Infections (10) · Hepatitis B (4) · Dengue (1) · Meningococcal Infections (1) · Pneumonia, Pneumococcal (1) · Severe Dengue (1)
Sanofi (7) · Sanofi Pasteur, a Sanofi Company (6) · China National Biotec Group Company Limited (1) · Institute of Medical Biology, Chinese Academy of Medical Sciences (1) · PATH (1) · Serum Institute of India Pvt. Ltd. (1) · Wyeth is now a wholly owned subsidiary of Pfizer (1)
China (4) · Argentina (2) · India (2) · Mexico (2) · South Korea (2) · France (1) · Kenya (1) · Philippines (1) · Russia (1) · South Africa (1) · Thailand (1) · Turkey (Türkiye) (1)
Lili Huang (1) · Nekoye Otsyula, MD (1)
PMID 21219984, PMID 21372751, PMID 22001281, PMID 22157567, PMID 22273029, PMID 27510380, PMID 30899835, PMID 41489614