17 completed, 5 active not recruiting, 2 recruiting, 2 unknown. 11 Phase 2, 10 Phase 3, 7 Phase 1, 4 Phase 4.
Follow Vaccines, Combined: new trials by email Literature Review of Vaccines, Combined trials Research Report on Vaccines, Combined
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Trial of the Adsorbed Acellular Pertussis (Tricomponent) DTaP-Haemophilus Influenzae Type b (Conjugate)-ACYW135 Group Meningococcal (Conjugate) Combined Vaccine Adsorbed Acellular Pertussis (3-Component) Diphtheria-Tetanus-Pertussis-Haemophilus influenzae type b (Conjugate)-Meningococcal Group ACYW135 (Conjugate) Combined Vaccine (DTcP-Hib-MCV4), DTcP-Hib-MCV4, Adsorbed Acellular Pertussis (3-Component) Diphtheria-Tetanus-Pertussis (DTcP) - Diphtheria, Tetanus and Acellular Pertussis, Epidemic Meningitis | Phase 1 | Recruiting | CanSino Biologics Inc. | 260 | 2025-12-19 | 2025-12-31 |
| Infant Malaria Vaccine Schedule Optimization R21 Matrix-M (R21/MM) Malaria Vaccine, Placebo, Hexavalent Vaccine - Malaria Vaccines, Malaria (Plasmodium Falciparum) | Phase 2 | Active not recruiting | PATH | 975 | 2025-05-30 | 2026-09-29 |
| A Phase II/III Study to Evaluate the Immunogenicity, Safety and Lot-to-lot Consistency of LBVD, a Fully Liquid Hexavalent Diphtheria-tetanus-whole Cell Pertussis-hepatitis B-poliovirus-Haemophilus Influenzae Type b Conjugate (DTwP-HepB-IPV-Hib) Vaccine, in Healthy Infants as Primary Series LBVD, Pentavalent vaccine and Inactivated Polio vaccine - Diphtheria, Tetanus | Phase 2 / Phase 3 | Active not recruiting | LG Chem | 1186 | 2025-05-30 | 2026-09-03 |
| Inter-lot Consistency Clinical Trial of Adsorbed Cell-free DTP (Three-component) Combined Vaccine Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed (DTcP Lot 1), Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed (DTcP Lot 2), Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed (DTcP Lot 3) - Diphtheria, Tetanus and Acellular Pertussis | Phase 3 | Active not recruiting | CanSino Biologics Inc. | 780 | 2025-03-23 | 2025-08-15 |
| Immunogenicity of Different Primary Immunization Schedules with Inactivated Poliovirus Vaccine (IPV) Plus Pentavalent Vaccine (DTwP-HBV-Hib) or with Hexavalent Vaccine (DTwP-HBV-Hib-IPV) Pentavalent vaccine, Hexavalent vaccine, Inactivated poliovirus vaccine (IPV) - Polio | Phase 4 | Not yet recruiting | International Centre for Diarrhoeal Disease Research, Bangladesh | 1190 | 2025-01-28 | 2024-12-27 |
| A Clinical Trials of Adsorbed Cell-free DPT Vaccine (Five-component) Tetanus, Reduced Diphtheria and Acellular Pertussis (Five Components) Combined Vaccine, Adsorbed (Tdcp)), 23-valent Pneumococcal Polysaccharide Vaccine (PPV23), Tdcp - Diphtheria, Tetanus | Phase 2 / Phase 3 | Completed | CanSino Biologics Inc. | 1820 | 2024-12-20 | 2026-08-26 |
| Immunogenicity and Safety of Diphtheria, Tetanus, Pertussis (DTaP) Vaccine in 3-month-old Infants Diphtheria, tetanus and acellular pertussis (component) combined vaccine (adsorbed), Diphtheria, tetanus and acellular pertussis combined vaccine (adsorbed), Diphtheria, tetanus, pertussis (acellular, component), poliomyelitis (inactivated) vaccine (adsorbed) and Haemophilus influenzae type b conjugate vaccine - Healthy Volunteers | Phase 3 | Recruiting | Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd | 1584 | 2023-12-21 | 2024-04-03 |
| A Clinical Trial of Adsorbed Cell-free DPT Vaccine (5-component) (for People Aged 6 Years and Above) Tetanus, Reduced Diphtheria and Acellular Pertussis (Five Components) Combined Vaccine, Adsorbed (Aged 6 Years and Older) (Tdcp), 23-Valent Pneumococcal Polysaccharide Vaccine（PPV23）, Diphtheria and Tetanus Combined Vaccine, Adsorbed (DT) - Diphtheria, Tetanus | Phase 1 | Completed | CanSino Biologics Inc. | 180 | 2023-12-06 | 2026-08-07 |
| A Clinical Trial of Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed(DTcP) Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed (DTcP), Diphtheria，Tetanus and Acellular Pertussis Combined Vaccine，DTaP, Diphtheria,tetanus,pertussis(acellular,component),Inactivated polio vaccine(adsorbed）and Haemophilus influenzae type b conjugate vaccine,adsorbed,DTaP-IPV-Hib - Diphtheria, Tetanus and Acellular Pertussis | Phase 3 | Active not recruiting | CanSino Biologics Inc. | 2520 | 2023-08-11 | 2025-03-17 |
| To Evaluate the Safety and Primary Immunogenicity of Cell-free (Three-component) Combination Vaccine for Phase I Immunogenicity in Children and Infants A single-center and single-arm design was used to evaluate the safety and preliminary immunogenicity of the adsorbed cell-free leukiche (three-component) combination vaccine - Safety、Immunogenicity | Phase 1 / Phase 2 | Unknown | Changchun BCHT Biotechnology Co. | 72 | 2021-12-10 | 2022-01-12 |
| A Phase 3 Study of BIBP Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed Diphtheria,Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed, Diphtheria,Tetanus and Acellular Pertussis Combined Vaccine, Adsorbed, Diphtheria,tetanus,pertussis(acellular,component),poliomyelitis(inactivated) vaccine(absorbed) and Haemophilus influenzae type b conjugate vaccine - Whooping Cough, Diphtheria | Phase 3 | Active not recruiting | China National Biotec Group Company Limited | 2898 | 2021-10-22 | 2025-09-15 |
| Clinical Study on the Combined Administration of 15-Valent Pneumococcal Conjugate Vaccine and Diphtheria, Tetanus, Pertussis Vaccine 15-Valent Pneumococcal Conjugate Vaccine and Diphtheria, Tetanus and Acellular pertussis (Component) Combined Vaccine (Adsorbed), Diphtheria, Tetanus and Acellular pertussis (Component) Combined Vaccine (Adsorbed) - Streptococcus Pneumoniae Infections | Phase 3 | Completed | Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd | 1110 | 2021-09-16 | 2025-02-10 |
| Annual Study for Collection of Serum Samples in Children and Older Adults Receiving the 2021-2022 Formulations of Fluzone Quadrivalent Vaccine and Fluzone High-Dose Quadrivalent Vaccine, Respectively Fluzone Quadrivalent vaccine, No Preservative (0.5-mL dose), 2021-2022 formulation, Fluzone High-Dose Quadrivalent vaccine (0.7-mL dose), 2021-2022 formulation - Influenza Immunization, Healthy Volunteers | Phase 4 | Completed | Sanofi Pasteur, a Sanofi Company | 90 | 2021-09-08 | 2025-09-12 |
| Annual Study for Collection of Serum Samples in Children and Older Adults Receiving the 2020-2021 Formulations of Fluzone Quadrivalent Vaccine and Fluzone High-Dose Quadrivalent Vaccine, Respectively Fluzone Quadrivalent vaccine, No Preservative (0.5-mL dose), 2020-2021 formulation, Fluzone High-Dose Quadrivalent vaccine (0.7-mL dose), 2020-2021 formulation - Influenza Immunization, Healthy Volunteers | Phase 4 | Completed | Sanofi Pasteur, a Sanofi Company | 90 | 2020-09-16 | 2025-09-12 |
| Phase I Clinical Trial of Diphtheria, Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed . Diphtheria,Tetanus and Acellular Pertussis (Three Components) Combined Vaccine, Adsorbed, Diphtheria and Tetanus Combined Vaccine, Adsorbed, Diphtheria-tetanus-acellular pertussis vaccine - Diphtheria, Tetanus | Phase 1 | Completed | CanSino Biologics Inc. | 400 | 2020-04-28 | 2022-10-31 |
| Safety and Immunogenicity of Hexavalent Vaccine(DTwP-HepB-IPV-Hib) in Healthy Infants DTwP-HepB-Sabin IPV-Hib, Pentavalent vaccine and Salk IPV - Diphtheria, Tetanus | Phase 2 | Unknown | LG Chem | 336 | 2019-11-01 | 2019-09-06 |
| Safety, Tolerability, and Immunogenicity of V114 in Healthy Japanese Infants (V114-028) V114, Pneumococcal 13-valent Conjugate Vaccine (PCV13), Adsorbed Diphtheria-purified Pertussis-tetanus-inactivated polio (Sabin strain) Combined Vaccine (DTaP-IPV) - Pneumococcal Infections | Phase 1 | Completed | Merck Sharp & Dohme LLC | 133 | 2019-04-02 | 2025-01-15 |
| Study to Evaluate the Immunogenicity and Safety of LBVD(Hexavalent Vaccine), Given to Healthy Infants at Primary Series LBVD (Hexavalent vaccine), Pentavalent vaccine and Inactivated Polio vaccine (Sabin strains) - Diphtheria, Tetanus | Phase 2 / Phase 3 | Completed | LG Chem | 60 | 2018-07-18 | 2026-09-03 |
| Study to Evaluate the Safety and Immunogenicity of a Multivalent Pneumococcal Vaccine Given With Prevnar 13 in Healthy Infants Multivalent, Prevnar 13 - Pneumococcal Infections | Phase 2 | Terminated | Pfizer | 565 | 2018-06-01 | 2021-11-30 |
| Trial to Evaluate the Safety and Immunogenicity of a Multivalent Pneumococcal Vaccine in Healthy Infants Multivalent, 13vPnC - Pneumococcal Infections | Phase 2 | Completed | Pfizer | 460 | 2018-04-16 | 2021-03-02 |
Showing 20 of 28. Sign in to see all of them.
Diphtheria (11) · Tetanus (11) · Pneumococcal Infections (7) · Whooping Cough (7) · Haemophilus Infections (5) · Poliomyelitis (4) · Hepatitis B (3) · Influenza, Human (2) · Bacterial Infections (1) · HIV Infections (1) · Infections (1) · Malaria, Falciparum (1) · Meningitis (1) · Meningitis, Meningococcal (1) · Meningococcal Infections (1)
CanSino Biologics Inc. (6) · Pfizer (5) · Sanofi Pasteur, a Sanofi Company (4) · LG Chem (3) · Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd (2) · Changchun BCHT Biotechnology Co. (1) · China National Biotec Group Company Limited (1) · Instituto Nacional de Salud Publica, Mexico (1) · International Centre for Diarrhoeal Disease Research, Bangladesh (1) · Merck Sharp & Dohme LLC (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · PATH (1) · Tanabe Pharma Corporation (1)
China (10) · United States (9) · Japan (2) · Burkina Faso (1) · Finland (1) · Mexico (1) · Philippines (1) · South Korea (1)
Yanxia Wang (2) · Aurelio Cruz, Valdez (1) · Edison Alberto, MD (1) · Eduardo C Lazcano, Phd, MD (1) · Hanqing He (1) · Janet L. Pacheco (1) · Josefina Carlos, MD (1) · Lili Huang (1) · Lin Du (1) · Lin Du, Doctor (1) · Tom Evans (1)
PMID 21085486, PMID 24355090, PMID 27939054, PMID 30085139, PMID 30471953, PMID 32716500, PMID 33661716, PMID 34525007, PMID 35144847, PMID 36882898, PMID 37927075, PMID 39384037, PMID 40977696, PMID 41276263, PMID 42483174