10 withdrawn. 10 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Withdrawn 10 |
| Phase 2 | 3 | Withdrawn 3 |
Follow Tauopathies: new trials by email Literature Review of Tauopathies trials Research Report on Tauopathies
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| First-In-Human (FIH), Single Ascending Dose (SAD) Study of FluoroEthylNorMemantine (FENM) Fluoroethylnormemantine (FENM) - PTSD, Alzheimer Disease | Phase 1 | Withdrawn | ReST Therapeutics | 2024-05-02 | 2024-05-03 | |
| Lymphatic System Health in Alzheimer's Disease Dexmedetomidine - Alzheimer Disease | Phase 1 | Withdrawn | Neurological Associates of West Los Angeles | 2021-12-10 | 2022-09-28 | |
| A Clinical Trial to Determine the Safety and Efficacy of Hope Biosciences Autologous Mesenchymal Stem Cell Therapy (HB-adMSCs) for the Treatment of Alzheimer's Disease HB-adMSCs - Alzheimer Disease | Phase 1 / Phase 2 | Withdrawn | Hope Biosciences LLC | 2020-03-01 | 2025-09-29 | |
| Multiple Dose Trial of MK-4334 in Participants With Alzheimer's Clinical Syndrome (MK-4334-005) MK-4334, Placebo to MK-4334, Donepepzil - Alzheimer's Disease, Mild Cognitive Impairment | Phase 1 | Withdrawn | Merck Sharp & Dohme LLC | 2019-09-27 | 2025-04-25 | |
| Medical Food Formulation Pharmacokinetic (PK) Study in Medium Chain Triglycerides MCTprocal medical food, Milk/tricaprilin oil blend, AC-1207 - Alzheimer Disease | Phase 1 | Withdrawn | Cerecin | 2019-02-13 | 2018-09-27 | |
| A FDG-PET Study of AGN-242071 Added to Standard-of-Care (Donepezil ± Memantine) for the Treatment of Participants With Mild to Moderate Alzheimer's Disease AGN-242071, Placebo, Donepezil - Alzheimer's Disease | Phase 1 | Withdrawn | Allergan | 2018-09-30 | 2018-11-02 | |
| Study to Determine the Effect of Itraconazole on the Pharmacokinetics of Rilapladib (SB659032) in Healthy Volunteers Rilapladib 25 mg, Rilapladib 250 mg, Itraconazole - Alzheimer's Disease | Phase 1 | Withdrawn | GlaxoSmithKline | 2017-10-01 | 2016-12-13 | |
| Mobile Phone App for Depression and Anxiety in Young Men Who Are Attracted to Men Mobile Phone Application - Depressive Symptoms, Anxiety Generalized | Phase 1 / Phase 2 | Withdrawn | Northwestern University | 2017-08-14 | 2017-08-17 | |
| Study to Assess the Safety and Effects of Autologous Adipose-Derived Stromal Cells in Patients With Alzheimer's Disease Liposuction under local anesthesia, Infusion of AD-SVF via IV and Intranasal - Alzheimer's Disease | Phase 1 / Phase 2 | Withdrawn | Ageless Regenerative Institute | 2015-11-01 | 2017-11-24 | |
| QTc Study of Rosi XR in Healthy Volunteers Rosi XR, Placebo, Moxifloxacin - Alzheimer's Disease | Phase 1 | Withdrawn | GlaxoSmithKline | 2009-06-01 | 2015-04-17 |
Alzheimer Disease (10) · Anxiety Disorders (1) · Bisexuality (1) · Brain Diseases (1) · Cognitive Dysfunction (1) · Depression (1) · Depressive Disorder, Major (1) · Depressive Disorder, Treatment-Resistant (1) · Generalized Anxiety Disorder (1) · Homosexuality (1) · Multiple Endocrine Neoplasia Type 1 (1) · Stress Disorders, Post-Traumatic (1)
Central Nervous System Diseases (10) · Dementia (10) · Mental Disorders (10) · Nervous System Diseases (10) · Neurocognitive Disorders (10) · Neurodegenerative Diseases (10) · Brain Diseases (9) · Behavior (1) · Behavioral Symptoms (1) · Cognition Disorders (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Depressive Disorder (1) · Endocrine Gland Neoplasms (1) · Endocrine System Diseases (1)
Donepezil (2) · AC-1202 (1) · Dexmedetomidine (1) · Itraconazole (1) · Memantine (1) · Moxifloxacin (1) · fluoroethylnormemantine (1) · rilapladib (1)
GlaxoSmithKline (2) · Ageless Regenerative Institute (1) · Allergan (1) · Cerecin (1) · Hope Biosciences LLC (1) · Merck Sharp & Dohme LLC (1) · Neurological Associates of West Los Angeles (1) · Northwestern University (1) · ReST Therapeutics (1)
United States (6) · Belgium (1) · United Kingdom (1)
Djamchid Lotfi, MD (1) · Michelle N Burns, Ph.D. (1) · Mitalee Tamhane, PhD (1) · Sharon McQuillan, MD (1) · Sheldon Jordan, MD (1)
K08MH094441 (1)