35 unknown. 35 Phase 1, 17 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 35 | Unknown 35 |
| Phase 2 | 17 | Unknown 17 |
Follow Tauopathies: new trials by email Literature Review of Tauopathies trials Research Report on Tauopathies
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Single Dose Escalation Study of HHT201 in Healthy Subjects Donepezil Dihydroxynaphthalate for Injection - Alzheimer Disease | Phase 1 | Unknown | Shanghai Synergy Pharmaceutical Sciences Co., Ltd. | 64 | 2024-06-01 | 2024-04-18 |
| Single Dose Escalation Study of CM383 in Healthy Volunteers CM383, Placebo - Alzheimer Disease | Phase 1 | Unknown | Keymed Biosciences Co.Ltd | 56 | 2024-05-28 | 2024-11-08 |
| A Phase I Study of DDN-A-0101 in Healthy Volunteers and Elder People DDN-A-0101 (SAD), DDN-A-0101 (MAD), Placebo (SAD) - Alzheimer Disease | Phase 1 | Unknown | Pharmacobio | 100 | 2024-04-01 | 2024-04-16 |
| A Study to Assess the Safety of BMS-984923 Compared to Placebo, in People With Parkinson's BMS-9894923 - Parkinson Disease | Phase 1 | Unknown | Allyx Therapeutics | 18 | 2024-03-15 | 2024-03-18 |
| Dose-Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics From Single Dose of Intramuscular (IM) and Subcutaneous (SC) Donepezil (GB-5001) Injections Versus Donepezil Oral Tablet (Aricept®) in Healthy Male Volunteers GB-5001A, GB-5001D, Oral cohort - Alzheimer Disease | Phase 1 | Unknown | G2GBio, Inc. | 56 | 2024-01-03 | 2023-12-22 |
| Tdap and Biomarkers of Alzheimer's Disease tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine - Alzheimer Disease, Late Onset | Phase 1 / Phase 2 | Unknown | Mindful Diagnostics and Therapeutics, LLC | 50 | 2023-05-01 | 2022-08-25 |
| Protecting Alzheimer Caregivers Using Technology Through Staying Sharp Staying Sharp intervention - Mild Cognitive Impairment, Dementia Alzheimers | Phase 1 / Phase 2 | Unknown | Oregon Health and Science University | 138 | 2023-04-30 | 2023-02-09 |
| Food Effect Study of BMS-984923 in Healthy Older Adult Volunteers BMS-984923 - Alzheimer Disease, Dementia | Phase 1 | Unknown | Allyx Therapeutics | 12 | 2023-01-10 | 2024-07-30 |
| A First-in-Human Study to Assess Single Doses of APNmAb005 in Healthy Participants APNmAb005, Placebo - Healthy Volunteers, Tauopathies | Phase 1 | Unknown | APRINOIA Therapeutics, LLC | 40 | 2022-05-06 | 2023-06-15 |
| [18F]MC225-PET in Neurodegenerative Disease [18F]MC225 - Neurodegenerative Diseases, Alzheimer Disease | Phase 1 / Phase 2 | Unknown | University Medical Center Groningen | 30 | 2022-02-01 | 2023-05-10 |
| Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of AD Emtriva Capsule, Placebo - Alzheimer Disease, Early Onset, Mild Cognitive Impairment | Phase 1 | Unknown | Butler Hospital | 35 | 2021-12-17 | 2025-05-04 |
| Exploring the Utility of [18F]3F4AP for Demyelination Imaging in Controls, Neurodegeneration and Traumatic Brian Injury F18-3F4AP - Brain Injuries, Traumatic, Demyelinating Disorder | Phase 1 | Unknown | Massachusetts General Hospital | 8 | 2021-01-25 | 2024-01-30 |
| Evaluation of Tolfenamic Acid in Individuals With PSP at 12-Weeks Tolfenamic Acid, Placebos - Progressive Supranuclear Palsy | Phase 1 / Phase 2 | Unknown | NeuroTau, Inc. | 24 | 2021-01-01 | 2020-02-05 |
| A Study of Possibility of Using Regulatory T Cells(VT301) for Treatment of Alzheimer's Disease VT301 - Alzheimer Disease | Phase 1 | Unknown | VTBIO Co. LTD | 12 | 2020-11-01 | 2021-08-23 |
| Mycose AdminiStration for HealIng Alzheimer NEuropathy (MASHIANE) Trehalose - Alzheimer Disease | Phase 1 | Unknown | Mashhad University of Medical Sciences | 20 | 2020-08-20 | 2020-12-11 |
| the Safety and the Efficacy Evaluation of Allogenic Adipose MSC-Exos in Patients With Alzheimer's Disease low dosage MSCs-Exos administrated for nasal drip, mild dosage MSCs-Exos administrated for nasal drip, high dosage MSCs-Exos administrated for nasal drip - Alzheimer Disease | Phase 1 / Phase 2 | Unknown | Ruijin Hospital | 9 | 2020-07-01 | 2021-06-25 |
| A Noval Tau Tracer in Young Onset Dementia 18F-PM-PBB3 - Alzheimer's Disease, Vascular Dementia | Phase 1 / Phase 2 | Unknown | Chang Gung Memorial Hospital | 100 | 2020-02-20 | 2020-01-30 |
| Transcranial Electromagnetic Treatment (TEMT) Against Alzheimer's Disease MemorEM - Alzheimer's Disease | Phase 1 / Phase 2 | Unknown | NeuroEM Therapeutics, Inc. | 6 | 2020-02-10 | 2020-02-17 |
| The Efficacy of Traditional Chinese Herbal Medicine for Alzheimer's Disease VGH-AD1 - Alzheimer Disease | Phase 1 / Phase 2 | Unknown | Taipei Veterans General Hospital, Taiwan | 28 | 2020-02-01 | 2020-01-31 |
| A Safety and Tolerability Study of GB301 Regulatory T cells, Saline - Alzheimer Disease | Phase 1 / Phase 2 | Unknown | VTBIO Co. LTD | 20 | 2019-12-01 | 2019-08-05 |
Showing 20 of 35. Sign in to see all of them.
Alzheimer Disease (32) · Cognitive Dysfunction (6) · Dementia (3) · Pick Disease of the Brain (3) · Parkinson Disease (2) · Supranuclear Palsy, Progressive (2) · Aphasia, Primary Progressive (1) · Brain Injuries, Traumatic (1) · Caregiver Burden (1) · Cognition Disorders (1) · Dementia, Vascular (1) · Demyelinating Diseases (1) · Health Behavior (1) · Neurodegenerative Diseases (1)
Brain Diseases (35) · Central Nervous System Diseases (35) · Nervous System Diseases (35) · Neurodegenerative Diseases (34) · Mental Disorders (33) · Neurocognitive Disorders (33) · Dementia (30) · Cognition Disorders (6) · Basal Ganglia Diseases (4) · Movement Disorders (4) · Pathological Conditions, Signs and Symptoms (4) · Frontotemporal Dementia (3) · Frontotemporal Lobar Degeneration (3) · Neurologic Manifestations (3)
AADvac1 (1) · Cohort Studies (1) · Emtricitabine (1) · Ibuprofen (1) · Injections (1) · MC225 compound (1) · Magnetic Resonance Spectroscopy (1) · Nerve Growth Factor (1) · Ointments (1) · Sagittal Abdominal Diameter (1) · Sodium Chloride (1) · Tetanus Toxoid (1) · Transcranial Magnetic Stimulation (1) · Trehalose (1) · mycophenolic adenine dinucleotide (1)
Allyx Therapeutics (2) · VTBIO Co. LTD (2) · APRINOIA Therapeutics, LLC (1) · Adeona Pharmaceuticals (1) · Affiliated Hospital to Academy of Military Medical Sciences (1) · American Society Of Thermalism And Climatology Inc (1) · Axon Neuroscience SE (1) · Butler Hospital (1) · CHABiotech CO., Ltd (1) · Centre Hospitalier Universitaire de Nice (1) · Chang Gung Memorial Hospital (1) · Cognoptix, Inc. (1) · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (1) · G2GBio, Inc. (1) · GAAD Medical Research Institute Inc. (1)
United States (12) · China (5) · South Korea (4) · Italy (2) · Australia (1) · Canada (1) · Colombia (1) · France (1) · Germany (1) · Iran (1) · Netherlands (1) · Sweden (1) · Taiwan (1)
Bin Zhang, M.D. Ph.D. (1) · Chao-Yi Wu, PhD (1) · Coad T Dow, MD (1) · David Newsome, M.D. (1) · Dongqing Lv (1) · Dongsheng Fan, M.D. (1) · Fontaine Denys, PhD (1) · Gang Wang, MD,PhD (1) · Garis Silega, Dr (1) · Gert Luurtsema, Phd (1) · Hu Chen, M.D., Ph.D. (1) · Hyun Sook Kim (1) · In-Jin Jang, Doctor (1) · Jaeyoon Kim (1) · Jeffrey Kaye, MD (1)
PMID 22655593, PMID 24438512, PMID 27160012, PMID 27389402, PMID 32375872, PMID 33933117, PMID 34670118, PMID 34712113, PMID 36170815, PMID 37859748, PMID 38690718, PMID 39626378, PMID 40235521, PMID 40368603
2017 (1), P30AG024978 (1), R01AG024010 (1)