5 not yet recruiting, 4 completed, 3 recruiting, 1 unknown. 8 Not applicable, 5 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 3, Not yet recruiting 3, Recruiting 2 |
| Phase 4 | 5 | Not yet recruiting 2, Completed 1, Recruiting 1, Unknown 1 |
Follow Surgical Stress Response: new trials by email Literature Review of Surgical Stress Response trials Research Report on Surgical Stress Response
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Bilateral Intermediate Cervical Plexus Block on the Surgical Stress Response Following Total Thyroidectomy Ultrasound-Guided Bilateral Intermediate Cervical Plexus Block Using 0,25% Levobupivacaine - Thyroidectomy, Cervical Plexus Block | Phase 4 | Not yet recruiting | University Hospital Dubrava | 48 | 2026-08-15 | 2026-08-07 |
| Timing Of Midazolam İn Children Undergoing Adenotonsillectomy: Effects On Stress, Cortisol, And Recovery Midazolam (Oral), Midazolam (Intravenous) - Adenotonsillectomy, Preoperative Anxiety | Not applicable | Not yet recruiting | Erzurum City Hospital | 100 | 2026-08-01 | 2026-06-10 |
| The Association Between Bilateral Intermediate Cervical Plexus Block and Salivary Biomarkers of Surgical Stress Response Following Total Thyroidectomy Ultrasound guided bilateral intermediate cervical plexus block - Surgical Stress Response, Total Thyroidectomy | Phase 4 | Not yet recruiting | University Hospital Dubrava | 48 | 2026-08-01 | 2026-07-23 |
| Feasibility of Breathwork Intervention With Older Adults After Knee Surgery A 5-minute Asynchronous Breathwork Intervention, A 5-minute Asynchronous Card Game Video - Surgical Stress Response, Stress Physiological | Not applicable | Recruiting | University of Arizona | 32 | 2026-07-01 | 2026-07-06 |
| Effect of Video-Based Versus Verbal Preoperative Information on Anxiety and Cortisol Levels in Elective Cesarean Section Verbal Preoperative Information, Video-Based Preoperative Information - Preoperative Anxiety, Cesarean Section | Not applicable | Completed | Elazıg Fethi Sekin Sehir Hastanesi | 140 | 2026-04-02 | 2026-08-26 |
| Guided Visualization Meditation for Reducing Surgical Stress Response in Cardiac Surgery Patients Guided Visualization Meditation - Cardiac Surgery, Surgical Stress Response | Not applicable | Not yet recruiting | University of Gaziantep | 72 | 2026-01-15 | 2026-02-02 |
| Effects of Intraoperative Warming Methods on Hematologic Inflammatory Indices in Laparoscopic Cholecystectomy Standard Active Warming Blanket, Intravenous Warmer Group, External Warmer Group - Inflammatory Response, Perioperative Hypothermia | Not applicable | Completed | Ataturk University | 128 | 2025-12-01 | 2026-10-13 |
| The Effect of Video-Supported Online Preoperative Education on Fear, Anxiety, Sleep, and Stress Patient education, Follow-up via Mobile Health Application - Patient Education, Surgical Fear and Worrying | Not applicable | Not yet recruiting | Bingol University | 128 | 2025-08-20 | 2025-08-03 |
| CoreSys Monitoring for Intraoperative Stress Management in Abdominal Hysterectomy propofol, CoreSys Monitor, Remifentanil (Target-Controlled Infusion) - Surgical Stress Response, Inflammation | Not applicable | Recruiting | Hospital Provincial de Rosario | 30 | 2025-01-08 | 2026-10-20 |
| The Effect of Nocturnal Dexmedetomidine on Postoperative Sleep Quality and Fatigue After Major Surgery in Elderly Patients: DEXSLEEP Study Placebo, Dexmedetomidine - Postoperative Fatigue, Postoperative Sleep Disturbances | Phase 4 | Completed | Ziekenhuis Oost-Limburg | 102 | 2024-06-03 | 2026-09-16 |
| The Association Between Bilateral Intermediate Cervical Plexus Block During Total Thyroidectomy and Surgical Stress Response bilateral ultrasound guided intermediate cervical plexus block with 0,25% levobupivacaine - Thyroid Cancer, Thyroid and Parathyroid Surgery | Phase 4 | Recruiting | University Hospital Dubrava | 48 | 2024-05-13 | 2026-06-16 |
| Intravenous Anesthesia by Targeted Controlled Infusion Versus Inhalational Anesthesia on the Surgical Stress Response Sevoflurane, Target Controlled Infusion, Target Controlled Infusion and lidocaine - Total Intravenous Anesthesia, Inhalational Anesthesia | Phase 4 | Unknown | Assiut University | 90 | 2023-10-07 | 2024-08-13 |
| The Effect of Music Played to Liver Transplant Donors During Surgery on Some Hemodynamic Values and Cortisol Levels Music Listening Intervention, Silence with Headphones - Surgical Stress Response | Not applicable | Completed | Hasan SARITAŞ | 90 | 2020-12-01 | 2025-05-30 |
Pain, Postoperative (2) · Anxiety Disorders (1) · Coronary Artery Disease (1) · Goiter (1) · Inflammation (1) · Insulin Resistance (1) · Postoperative Complications (1) · Sleep Initiation and Maintenance Disorders (1) · Stress, Psychological (1) · Thyroid Diseases (1) · Thyroid Neoplasms (1)
Pathologic Processes (3) · Pathological Conditions, Signs and Symptoms (3) · Mental Disorders (2) · Neurologic Manifestations (2) · Pain (2) · Signs and Symptoms (2) · Arterial Occlusive Diseases (1) · Arteriosclerosis (1) · Behavior (1) · Behavioral Symptoms (1) · Cardiovascular Diseases (1) · Coronary Disease (1) · Dyssomnias (1) · Endocrine Gland Neoplasms (1) · Endocrine System Diseases (1)
Dexmedetomidine (1) · Lidocaine (1) · Midazolam (1) · Patient Education as Topic (1) · Propofol (1) · Remifentanil (1) · Sevoflurane (1)
University Hospital Dubrava (3) · Assiut University (1) · Ataturk University (1) · Bingol University (1) · Elazıg Fethi Sekin Sehir Hastanesi (1) · Erzurum City Hospital (1) · Hasan SARITAŞ (1) · Hospital Provincial de Rosario (1) · University of Arizona (1) · University of Gaziantep (1) · Ziekenhuis Oost-Limburg (1)
Turkey (Türkiye) (6) · Argentina (1) · Belgium (1) · Croatia (1) · Egypt (1) · United States (1)
Devon E Cobos Garcia, PhD Candidate (1) · Mehmet Sercan Orbak, MD (1) · Ruth E Taylor-Piliae, PhD (1) · Thaddeus W W Pace, PhD (1)
PMID 10927999, PMID 19137808, PMID 26275092, PMID 28187050, PMID 28341079, PMID 30459033, PMID 31289589, PMID 32799802, PMID 33456967, PMID 34444504, PMID 36030214, PMID 36040069, PMID 36658058, PMID 36681771, PMID 37830734, PMID 38935953, PMID 39736577, PMID 40595941