68 completed, 41 unknown, 26 recruiting, 11 terminated. 49 Not applicable, 7 Phase 4, 6 Phase 3, 3 Phase 2, 1 Phase 1.
Follow Sudden Cardiac Death: new trials by email Literature Review of Sudden Cardiac Death trials Research Report on Sudden Cardiac Death
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cardiovascular Pre-participation Screening in Children and Adolescents Pre-participation clinical evaluation, Diagnostic Test: Resting 12-lead electrocardiogram, Diagnostic Test: Step test (Harvard step test) - Sudden Cardiac Death, Cardiac Arrhythmias | Not yet recruiting | University of Sao Paulo | 334 | 2027-02-01 | 2026-10-15 | |
| Digital MEDIcal TWIN for the Prediction of Arrhythmic Sudden Cardiac Death After a Myocardial Infarction Programmed ventricular stimulation, Cardiac CT scan - Sudden Cardiac Death, Myocardial Infarction | Not applicable | Not yet recruiting | University Hospital, Bordeaux | 1000 | 2026-04-15 | 2026-04-14 |
| Functional Substrate-Only Guided VT Ablation Functional Substrate-Only Mapping without VT Induction, Standard-of-Care Mapping/Imaging - Ventricular Tachycardia, Sudden Cardiac Death | Not applicable | Enrolling by invitation | VA Office of Research and Development | 36 | 2026-03-18 | 2026-03-25 |
| Skeletal Muscle Multi-omics Analysis and Risk Tailoring in Sudden Cardiac Death Sudden Cardiac Death | Not yet recruiting | China National Center for Cardiovascular Diseases | 421 | 2026-03-16 | 2026-03-17 | |
| Dilated Cardiomyopathy - Unknown Therapeutic Risk Reduction by Contempary Medication and Implantable Cardioverter-Defibrillators (DUTCH-ICD) ICD implantation - Sudden Cardiac Death | Not applicable | Not yet recruiting | University Medical Center Groningen | 720 | 2026-03-01 | 2026-02-17 |
| Left Bundle Branch Pacing in Patients With Hypertrophic Cardiomyopathy After Myectomy ICD with left bundle branch area pacing (LBBAP), dual-chamber ICD - HCM - Hypertrophic Cardiomyopathy, Sudden Cardiac Death | Not applicable | Recruiting | Meshalkin Research Institute of Pathology of Circulation | 30 | 2025-11-14 | 2026-01-28 |
| Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator Metoprolol Succinate, Carvedilol - Heart Failure With Reduced Ejection Fraction (HFrEF), Sudden Cardiac Death | Phase 4 | Recruiting | University of Rochester | 2000 | 2025-08-17 | 2025-09-18 |
| National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry whole genome sequencing - Cardiomyopathy, Hypertrophic, Cardiomyopathy, Dilated | Recruiting | Hospital do Coracao | 1211 | 2025-04-30 | 2026-05-08 | |
| Mechanisms And Prognosis of Stroke-Heart Syndrome Stroke, Myocardial Injury | Recruiting | Chensheng Pan | 658 | 2025-03-01 | 2025-05-01 | |
| S-ICD Implantation: US Based Pilot Study Intraoperative PRAETORIAN Score - Sudden Cardiac Death | Not applicable | Recruiting | Universitätsklinikum Köln | 20 | 2025-03-01 | 2025-07-09 |
| Tampere Coronary Artery Disease and Sudden Cardiac Arrest Study Sudden Cardiac Arrest, Sudden Cardiac Death | Recruiting | Tampere Heart Hospital | 4000 | 2025-01-13 | 2026-08-25 | |
| Validation of Sudden Cardiac Arrest Risk Factors in Patients With CAD Coronary Arterial Disease (CAD), Sudden Cardiac Arrest | Recruiting | Tampere Heart Hospital | 1500 | 2025-01-05 | 2026-08-25 | |
| Sudden Cardiac Arrest Related to Sport in Young and Value of the Genetic Assessment: a French Prospective Register Whole exome sequencing to detect myocardial genetic mutations (SCA group only) - Sudden Cardiac Arrest, Sudden Cardiac Death | Recruiting | Rennes University Hospital | 80 | 2024-10-11 | 2026-08-25 | |
| Speed-up the Diagnosis and Evaluation of anoMalous Coronary ARTery From the Aorta Autonomic response in AAOCA - AAOCA, ACAOS | Not applicable | Recruiting | IRCCS Policlinico S. Donato | 38 | 2024-09-12 | 2026-10-13 |
| Early Double Sequential Defibrillation in Out-of-hospital Cardiac Arrest Double Sequential Defibrillation (DSD), Standard defibrillation - Cardiac Arrest, Fibrillation, Ventricular | Not applicable | Completed | Karolinska Institutet | 40 | 2024-08-01 | 2025-10-01 |
| MAgnetic Resonance Imaging-guided implanTation of Cardioverter DEFibrillators MRI screening, Implantable Loop Recorder, Implantable Cardioverter Defibrillator - Myocardial Infarction, Ventricular Tachycardia | Not applicable | Not yet recruiting | Central Hospital, Nancy, France | 1812 | 2024-04-01 | 2024-02-21 |
| Multicenter Evaluation of Patients Using LATITUDE Monitoring System Cardiovascular Diseases, Arrhythmias, Cardiac | Recruiting | University Hospital of Ferrara | 20000 | 2023-12-01 | 2024-08-12 | |
| Prevention Of Sudden Cardiac Death After Myocardial Infarction by Defibrillator Implantation Implantable cardioverter-defibrillator (ICD), Optimal Medical Therapy (OMT) - Sudden Cardiac Death, Myocardial Infarction | Not applicable | Recruiting | Charite University, Berlin, Germany | 3595 | 2023-11-16 | 2026-04-01 |
| S-ICD Electrode Registry ICD Malfunction, Sudden Cardiac Death | Unknown | Universitätsklinikum Köln | 1000 | 2023-11-01 | 2023-10-13 | |
| Post-market Surveillance of Micorport CRM Cardiac Implantable Electronic Devices Implantation of a CIED - Cardiac Rhythm Disorder, Heart Failure | Recruiting | MicroPort CRM | 2500 | 2023-10-30 | 2024-01-17 |
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Death, Sudden, Cardiac (157) · Heart Failure (39) · Arrhythmias, Cardiac (35) · Tachycardia, Ventricular (30) · Ventricular Fibrillation (21) · Myocardial Infarction (16) · Heart Arrest (15) · Cardiomyopathies (13) · Cardiovascular Diseases (12) · Cardiomyopathy, Dilated (7) · Myocardial Ischemia (6) · Heart Defects, Congenital (5) · Ventricular Dysfunction, Left (5) · Arrhythmogenic Right Ventricular Dysplasia (4) · Cardiomyopathy, Hypertrophic (4)
Pathologic Processes (157) · Pathological Conditions, Signs and Symptoms (157) · Death, Sudden (156) · Heart Diseases (154) · Death (153) · Cardiovascular Diseases (145) · Heart Arrest (142) · Arrhythmias, Cardiac (37) · Cardiac Conduction System Disease (36) · Vascular Diseases (32) · Tachycardia (30) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (26) · Myocardial Ischemia (21) · Infarction (17) · Ischemia (17)
Defibrillators, Implantable (12) · Blood Specimen Collection (2) · Electrocardiography (2) · Exercise (2) · Genetic Testing (2) · Hematologic Tests (2) · Metoprolol (2) · Standard of Care (2) · Adrenergic beta-Antagonists (1) · Beverages (1) · Cardiac Rehabilitation (1) · Cardiac Resynchronization Therapy (1) · Carvedilol (1) · Defibrillators (1) · Diagnostic Imaging (1)
Abbott Medical Devices (6) · Boston Scientific Corporation (5) · Maastricht University Medical Center (4) · Zoll Medical Corporation (4) · Biotronik SE & Co. KG (3) · Centro Medico Teknon (3) · Charite University, Berlin, Germany (3) · Johns Hopkins University (3) · Technical University of Munich (3) · University of California, Los Angeles (3) · Assistance Publique - Hôpitaux de Paris (2) · China National Center for Cardiovascular Diseases (2) · Guidant Corporation (2) · Helios Health Institute GmbH (2) · IRCCS Policlinico S. Donato (2)
United States (42) · Germany (26) · France (17) · Italy (12) · Canada (11) · China (9) · Spain (9) · United Kingdom (8) · Netherlands (7) · Switzerland (6) · Austria (5) · Israel (5) · Poland (5) · Denmark (4) · South Korea (4)
Antonio Berruezo, MD, PhD (3) · Nikolaos Dagres, MD (3) · Gerhard Hindricks, MD (2) · Grzegorz Opolski, Professor (2) · Jingfeng Wang, M.D.,Ph.D. (2) · Michael Gold, MD, PhD (2) · Paul Volders, MD, PhD (2) · Ratna Mukherjea, PhD (2) · Akil Awad, MD, PhD (1) · Alain Cariou, MD, PhD (1) · Alan Kadish, MD (1) · Allfred P Hallstrom, PhD (1) · Amir Hedayati, MD (1) · Andreas Claesson, RN, PhD (1)
PMID 10716483, PMID 12030525, PMID 12975406, PMID 14510658, PMID 14625108, PMID 14760317, PMID 15337224, PMID 16022960, PMID 16105845, PMID 16338936, PMID 16755342, PMID 17045899, PMID 18565399, PMID 18565861, PMID 18940888, PMID 19264245, PMID 19465439, PMID 19538734, PMID 19632624, PMID 19646801, PMID 19687165, PMID 19695461, PMID 19700170, PMID 19708226, PMID 19808416, PMID 19808478, PMID 20369058, PMID 20855658, PMID 21087331, PMID 21091740, PMID 21146669, PMID 21315841, PMID 21448080, PMID 21699842, PMID 21699869, PMID 21835757, PMID 22035077, PMID 22117037, PMID 22267750, PMID 22543737, PMID 22615341, PMID 22626743, PMID 22750217, PMID 22826079, PMID 22841828, PMID 22858384, PMID 22939041, PMID 22995383, PMID 23210764, PMID 23416373
2016 (1), OT2OD028201 (1), R01HL077398 (1), R01HL091069 (1), R01HL165840 (1), R21HL106586 (1), R44HL082088 (1)