11 recruiting, 7 completed, 2 active not recruiting, 1 not yet recruiting. 11 Not applicable, 2 Phase 2, 1 Phase 1, 1 Phase 3.
Follow Subjective Cognitive Impairment: new trials by email Literature Review of Subjective Cognitive Impairment trials Research Report on Subjective Cognitive Impairment
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Physiological Effect of Non-invasive Photobiomodulation on Cognition and Mood in Older Adults With Subjective Cognitive Impairment Photobiomodulation, Sham (No Treatment) - Subjective Cognitive Decline (SCD), Subjective Cognitive Impairment | Not applicable | Not yet recruiting | Baycrest | 80 | 2026-06-01 | 2026-03-03 |
| The Brain Health PRO Online Risk Factor Reduction Study to Prevent Dementia Brain Health PRO - Dementia Prevention, Subjective Cognitive Impairment | Not applicable | Recruiting | University of British Columbia | 700 | 2026-05-07 | 2026-05-19 |
| Comfortage - AD Prevention Strategies Neuropsychological Assessments and Other Questionnaires, Blood Exams, Fluid Biomarkers, Genetics, Connectivity Analysis - Alzheimer Disease, Subjective Cognitive Impairment | Not applicable | Active not recruiting | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 200 | 2025-10-07 | 2026-09-03 |
| The Signature of Alzheimer's Disease in Subjective Cognitive Decline Subjective Cognitive Decline (SCD), Subjective Cognitive Complaints (SCCs) | Recruiting | IRCCS Policlinico S. Donato | 250 | 2025-10-01 | 2026-02-11 | |
| A Study Evaluating the Impact of P-tau217 Blood Biomarker Testing on Early Evaluation and Management of Patients Presenting With Cognitive Complaint P-tau217, Standard of Care - Subjective Cognitive Impairment | Not applicable | Recruiting | Eli Lilly and Company | 7000 | 2025-08-22 | 2026-11-04 |
| Effect of a Multidomain Intervention Plus Turmeric on the Prevention of Cognitive Decline in People Over 55 Years of Age With Insulin Resistance. Turmeric extract, Control: Placebo. 500mg gelatin in capsules 2 times a day - Cognitive Decline, Subjective Cognitive Impairment | Phase 2 / Phase 3 | Active not recruiting | Instituto Mexicano del Seguro Social | 100 | 2025-02-20 | 2026-03-25 |
| Testing the Cog-Fun Aging Program for Older Adults With Subjective Cognitive Decline Cog Fun Ageing intervention, Cog-Fun Aging Crossover - Subjective Cognitive Decline (SCD), Subjective Cognitive Impairment | Not applicable | Completed | Hebrew University of Jerusalem | 27 | 2024-11-20 | 2026-09-03 |
| Effects of a Computerised Cognitive Stimulation Versus Stimulating Leisure Activities Cognitive stimulation, Stimulating leisure activities - Mild Cognitive Impairment, Randomized Controlled Trial | Not applicable | Recruiting | Universidad de Zaragoza | 90 | 2024-04-01 | 2024-12-12 |
| CogT pSOPT Intervention Study pSOPT, MLA - Mild Cognitive Impairment, Subjective Cognitive Impairment | Phase 1 | Recruiting | Stanford University | 50 | 2024-01-12 | 2024-05-17 |
| Sleep Apnea, Neurocognitive Decline and Brain Imaging in Patients With Subjective or Mild Cognitive Impairment Continuous Positive Airway Pressure or other management for OSA per clinical indications. - Obstructive Sleep Apnea, Mild Cognitive Impairment | Recruiting | The University of Hong Kong | 180 | 2023-09-26 | 2025-04-02 | |
| Sleep Apnea and Cognitive Function in Subjects With Subjective or Mild Cognitive Impairment Home Sleep Apnea test (HSAT) - Obstructive Sleep Apnea, Mild Cognitive Impairment | Recruiting | The University of Hong Kong | 250 | 2023-03-07 | 2025-04-02 | |
| Natives Engaged in Alzheimers Research - 'Ike Kupuna Ola Mau i ka Hula - Mild Cognitive Impairment, Subjective Cognitive Impairment | Not applicable | Recruiting | University of Hawaii | 192 | 2022-09-15 | 2024-08-01 |
| Long Term Prospective Study of Tai Chi Intervention to Delay the Progression of Subjective Cognitive Impairment Tai chi training, Group activity - Subjective Cognitive Impairment | Not applicable | Unknown | Ruijin Hospital | 134 | 2022-09-01 | 2022-08-02 |
| Brain Health Support Program Brain Health PRO - Dementia Prevention, Mild Cognitive Impairment | Not applicable | Completed | Baycrest | 354 | 2022-04-06 | 2025-05-02 |
| A Pilot Study for the Brain Health Support Program Brain Health PRO - Dementia, Mild Cognitive Impairment | Completed | Baycrest | 20 | 2021-11-15 | 2026-01-16 | |
| Cerebrovascular Reactivity in Alzheimer's Disease Doppler ultrasonography, Biospecimen collection - Alzheimer Disease, Subjective Cognitive Impairment | Completed | Assistance Publique - Hôpitaux de Paris | 58 | 2019-10-22 | 2024-06-24 | |
| Tailored Mediterranean Lifestyle Education in Participants With Subjective Cognitive Impairment "THINK-MED" resource (baseline), "THINK-MED" resource (staged), Control - Subjective Cognitive Impairment | Not applicable | Completed | Queen's University, Belfast | 5 | 2018-05-18 | 2024-04-03 |
| Molecular Mediators of Physical Exercise and Carnosine Induced Effects in Patients With Preclinical and Early Stage Neurodegenerative Disease exercise, carnosine supplementation, stretching - Subjective Cognitive Impairment, Mild Cognitive Impairment | Not applicable | Completed | Slovak Academy of Sciences | 26 | 2017-01-01 | 2025-05-28 |
| Comprehensive Assessment of Neurodegeneration and Dementia Dementia, Mild Cognitive Impairment (MCI) | Recruiting | McGill University | 1573 | 2016-06-01 | 2026-01-20 | |
| Uppsala-Dalarna Dementia and Gait Project Timed Up-and-Go (TUG single-task), Timed Up-and-Go dual-task (TUGdt), Clinical functional assessment - Dementia, Dementia, Mixed | Recruiting | Dalarna University | 550 | 2015-04-09 | 2025-02-12 |
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Cognitive Dysfunction (15) · Alzheimer Disease (6) · Dementia (4) · Mixed Dementias (2) · Parkinson Disease (2) · Sleep Apnea, Obstructive (2) · Dementia, Vascular (1) · Frontotemporal Dementia (1) · Gait Apraxia (1) · Insulin Resistance (1) · Lewy Body Disease (1) · Memory Disorders (1) · Neurodegenerative Diseases (1) · Speech (1)
Cognition Disorders (15) · Mental Disorders (15) · Neurocognitive Disorders (15) · Nervous System Diseases (11) · Brain Diseases (8) · Central Nervous System Diseases (8) · Neurodegenerative Diseases (6) · Tauopathies (6) · Dementia (3) · Apnea (2) · Basal Ganglia Diseases (2) · Dyssomnias (2) · Metabolic Diseases (2) · Movement Disorders (2) · Neurobehavioral Manifestations (2)
BaseLine dental cement (1) · Continuous Positive Airway Pressure (1) · Dietary Supplements (1) · Exercise (1) · Exercise Therapy (1) · Gelatin (1) · Low-Level Light Therapy (1) · Memantine (1) · Nutritional Status (1) · Standard of Care (1) · Ultrasonography, Doppler, Transcranial (1) · salicylhydroxamic acid (1) · turmeric extract (1)
Baycrest (3) · The University of Hong Kong (2) · Assistance Publique - Hôpitaux de Paris (1) · Dalarna University (1) · Eli Lilly and Company (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Hebrew University of Jerusalem (1) · IRCCS Policlinico S. Donato (1) · Instituto Mexicano del Seguro Social (1) · Manuel Montero Odasso (1) · McGill University (1) · Merz Pharmaceuticals GmbH (1) · Queen's University, Belfast (1) · Ruijin Hospital (1) · Slovak Academy of Sciences (1)
Canada (6) · United States (3) · Hong Kong (2) · Italy (2) · United Kingdom (2) · China (1) · France (1) · Germany (1) · Israel (1) · Mexico (1) · Slovakia (1) · Spain (1) · Sweden (1) · Taiwan (1)
Adina Maeir, PhD (1) · Dr. Manuel Montero Odasso, M.D. (1) · Jaspreet Bhangu, MB (1) · Jayne Woodside, PhD (1) · Joseph K Kaholokula, PhD (1) · Jozef Ukropec, DrSc, PhD (1) · Mary SM Ip, MD (1) · Michael Borrie, MD (1) · Natalie Philips, PhD (1)
PMID 40090784, PMID 32727472, PMID 33017671, PMID 33153203, PMID 33390187, PMID 37660032, PMID 37874110, PMID 40097949, PMID 41278371, PMID 41572419, PMID 41585362