33 completed, 11 unknown, 5 terminated, 4 recruiting. 56 Phase 3, 13 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 56 | Completed 33, Unknown 11, Terminated 5, Recruiting 4, Active not recruiting 1, Not yet recruiting 1, Withdrawn 1 |
| Phase 2 | 13 | Completed 6, Unknown 4, Terminated 2, Recruiting 1 |
Follow Stomatitis: new trials by email Literature Review of Stomatitis trials Research Report on Stomatitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Protective Role of Alpha-Lipoic Acid in Chemotherapy-Induced Mucositis alpha lipoic acid 600 mg twice daily, Placebo Tablet - Colorectal Cancer | Phase 2 / Phase 3 | Recruiting | Ain Shams University | 50 | 2026-07-27 | 2026-07-30 |
| A Clinical Study to Compare BupiZenge With Lidocaine for Pain Due to Oral Mucositis in Patients With Head and Neck Cancer. BupiZenge 25 mg, Lidocaine viscous 2% - Head & Neck Cancer, Oral Mucositis | Phase 3 | Recruiting | OncoZenge AB | 150 | 2026-07-07 | 2026-10-27 |
| Traditional Chinese Medicine for the Prevention of Radiotherapy-Induced Oral Mucositis (RTOM) Modified Dahuang Huanglian Xiexin Mouthwash, Placebo Mouthwash - Radiotherapy-Induced Oral Mucositis, Stomatitis | Phase 3 | Not yet recruiting | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 156 | 2026-04-30 | 2026-04-22 |
| Efficacy and Safety of BALI Association in the Treatment of Aphthous Ulcerations BALI association, Placebo - Aphthous Stomatitis | Phase 3 | Unknown | EMS | 232 | 2024-09-01 | 2024-02-16 |
| Safety and Efficacy of N-Acetylcysteine Mouthwash in Prevention of Mucositis in HSCT Patients N-Acetylcysteine 600mg/tab, Placebo - Oral Mucositis, Hematopoietic Stem Cell Transplantation (HSCT) | Phase 3 | Active not recruiting | Tehran University of Medical Sciences | 106 | 2024-08-18 | 2026-01-08 |
| Glutamine Combined With Thalidomide in Preventing Radiation-induced Oral Mucositis glutamine combined with thalidomide, glutamine alone - Mucositis Oral | Phase 3 | Completed | Air Force Military Medical University, China | 138 | 2023-09-15 | 2026-07-01 |
| Low Power Laser Therapy As Prevention Of Oral Mucositis And Oropharyngeal Pain In Patients Undergoing Allogenetic HSCT Double low-power laser therapy simultaneous applicated - Hematopoietic Stem Cell Transplantation, Low-Level Light Therapy | Phase 3 | Recruiting | Instituto Nacional de Cancer, Brazil | 84 | 2023-08-01 | 2023-10-06 |
| Methylene Blue Mouthwash for the Treatment of Oral Mucositis Pain in Patients With Cancer Anti-inflammatory/Antimicrobial/Analgesic Aqueous Mouth Rinse, Methylene Blue Oral Rinse - Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm | Phase 3 | Completed | Mayo Clinic | 49 | 2023-06-06 | 2025-04-30 |
| NATIENS: Optimal Management and Mechanisms of SJS/TEN Harmonized supportive care, Etanercept 50 mg sc day 1 and day 4 - Stevens-Johnson Syndrome, Toxic Epidermal Necrolyses | Phase 3 | Completed | Vanderbilt University Medical Center | 2 | 2023-03-21 | 2025-12-17 |
| A Prospective Study on the Therapeutic Outcomes of Mebo and Tantum Verde in Patients With Oral Mucositis MEBO Wound Ointment (MEBO), Tantum Verde® mouthwash - Oral Mucositis (Ulcerative) Due to Radiation | Phase 3 | Completed | Cairo University | 36 | 2023-03-01 | 2025-09-22 |
| Efficacy of EGF-loaded Self Healing Gel in Treatment of Oral Mucositis EGF loaded Hydrogel, Hydrogel - Oral Mucositis | Phase 2 / Phase 3 | Unknown | Cairo University | 90 | 2022-06-01 | 2021-08-06 |
| Severe Bullous Drug Eruption and Filgrastim Filgrastim, Placebo - Rare Diseases, Toxic Epidermal Necrolyses | Phase 2 / Phase 3 | Unknown | Hospices Civils de Lyon | 42 | 2022-05-13 | 2024-05-08 |
| Omega-3 Hydrogel and Prevention of Oral Mucositis topical oral Omega-3 hydrogel, conventional preventive treatment - Mucositis Oral | Phase 2 / Phase 3 | Completed | Basma Morsy | 36 | 2022-02-09 | 2023-01-31 |
| Treatment of Chemotherapy and Radiotherapy Induced Oral Mucositis Benzydamine Hydrochloride, Solcoseryl and pumpkin seed oil - Mucositis Oral | Phase 3 | Unknown | Ghada zaki | 54 | 2021-12-01 | 2021-08-06 |
| Using Vitamin D to Reduce Oral Mucosal Inflammation in Chemotherapy Patients With Oral Squamous Cell Carcinoma Alfacalcidol Oral Solution, Placebo - Oral Squamous Cell Carcinoma, Oral Mucositis | Phase 2 / Phase 3 | Unknown | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 412 | 2021-06-14 | 2023-08-29 |
| Clonidine HCl MBT vs. Placebo to Prevent Chemoradiotherapy-Induced Severe Oral Mucositis in Oropharyngeal Cancer. Clonidine HCl Mucoadhesive Buccal Tablet, Placebo Mucoadhesive Buccal Tablet - Chemoradiotherapy-Induced Severe Oral Mucositis | Phase 2 / Phase 3 | Terminated | Monopar Therapeutics | 190 | 2021-02-11 | 2023-05-31 |
| Compound Staphylococcal Lysostaphin Vs. Chlorhexidine Mouthrinse for Oral Mucositis in Patients Undergoing Allo-HSCT compound Staphylococcal lysostaphin mouthrinse, chlorhexidine mouthrinse - Stem Cell Transplant Complications, Oral Mucositis | Phase 3 | Completed | Zhejiang University | 388 | 2020-01-02 | 2025-01-24 |
| Comparative Efficacy of Rebamipide Gargle And Benzydamine HCL Gargle in Prevention and Management of Chemo- and Radio-therapy-induced Oral Mucositis Ribamipide gargle \benzdymine HCL gargel - Oral Mucositis | Phase 3 | Unknown | Cairo University | 100 | 2019-12-26 | 2020-12-28 |
| Topical Hyaluronic Acid and Recurrent Aphthous Stomatitis. Hyaluronic acid in the form of hyaluronan sodium 25 mg/100 ml as a mouthwash - Recurrent Aphthous Stomatitis | Phase 3 | Completed | Cairo University | 34 | 2019-11-01 | 2020-02-11 |
| Evaluate the Efficacy of Selenium for the Prevention of Chemotherapy-induced Mucositis During Autologous Stem Cell Transplantation. Selenium, Placebos - Mucositis Oral, Stem Cell Transplant Complications | Phase 3 | Completed | University Hospital, Angers | 100 | 2019-10-10 | 2024-12-30 |
Showing 20 of 56. Sign in to see all of them.
Head and Neck Neoplasms (11) · Mucositis (8) · Neoplasms (8) · Stevens-Johnson Syndrome (5) · Carcinoma, Squamous Cell (4) · Oral Ulcer (3) · Squamous Cell Carcinoma of Head and Neck (3) · Stomatitis, Aphthous (3) · Ulcer (3) · Candidiasis, Oral (2) · Inflammation (2) · Oropharyngeal Neoplasms (2) · Pain (2) · Radiation Injuries (2)
Mouth Diseases (56) · Stomatognathic Diseases (56) · Neoplasms by Site (17) · Neoplasms (14) · Digestive System Diseases (11) · Gastrointestinal Diseases (10) · Neoplasms by Histologic Type (9) · Pathological Conditions, Signs and Symptoms (9) · Gastroenteritis (8) · Neoplasms, Glandular and Epithelial (8) · Carcinoma (7) · Immune System Diseases (6) · Pathologic Processes (6) · Chemically-Induced Disorders (5)
Fibroblast Growth Factor 7 (5) · Low-Level Light Therapy (5) · Benzydamine (2) · Glutamine (2) · 1-phenyl-3,3-dimethyltriazene (1) · Acetylcysteine (1) · Actihaemyl (1) · Anthocyanins (1) · Anti-Inflammatory Agents (1) · Ascorbic Acid (1) · Biotene (1) · Cisplatin (1) · Diphenhydramine (1) · Etanercept (1) · Filgrastim (1)
Cairo University (4) · Amgen (3) · Instituto Nacional de Cancer, Brazil (2) · Swedish Orphan Biovitrum (2) · University of Sao Paulo (2) · Ain Shams University (1) · Air Force Military Medical University, China (1) · All India Institute of Medical Sciences (1) · Basma Morsy (1) · Biotec Pharmacon ASA (1) · Centre Leon Berard (1) · Daewoong Pharmaceutical Co. LTD. (1) · EMS (1) · Endo USA Inc., a Keenova Therapeutics Company (1) · Galera Therapeutics, Inc. (1)
United States (11) · France (8) · Brazil (7) · Egypt (5) · China (4) · Germany (3) · India (3) · Canada (2) · Iran (2) · Puerto Rico (2) · Spain (2) · Belgium (1) · Denmark (1) · Italy (1) · Japan (1)
Atul Sharma, MD,DM (1) · Basma AA Zakaria, PhD (1) · Brian M Feldman, MD, MSc (1) · Carlos G Ferreira, MD, PhD (1) · Christine B. Boers-Doets, MSc (1) · Dietger Niederwieser, Professor (1) · Donald T Tan, FRCS (1) · Elizabeth J Phillips, MD (1) · Erica N Lia, PhD (1) · Flavia A de Orange, PhD (1) · Gene Kennedy, MD (1) · Gisela M Pina, DDS (1)
PMID 10423050, PMID 15161841, PMID 15287367, PMID 15602019, PMID 16161031, PMID 16391299, PMID 16415901, PMID 16862549, PMID 17580258, PMID 18413833, PMID 18696746, PMID 18754720, PMID 19125084, PMID 19733615, PMID 20141576, PMID 21394411, PMID 21473845, PMID 21537592, PMID 21741230, PMID 21911312, PMID 22057503, PMID 22077475, PMID 22467697, PMID 24119379, PMID 25161649, PMID 25198431, PMID 26559740, PMID 26916845, PMID 31618127, PMID 34145168, PMID 35634695, PMID 38824583, PMID 41127563, PMID 42829889
2018 (1), 2025 (1), R01CA107080 (1)