5 completed, 1 terminated, 1 withdrawn. 3 Not applicable, 3 Phase 4, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 3 |
| Phase 4 | 3 | Completed 2, Withdrawn 1 |
| Phase 3 | 1 | Terminated 1 |
Follow Biotene: new trials by email Literature Review of Biotene trials Research Report on Biotene
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Evaluation of MucoPEG™ for Xerostomia MucoPEG, Biotene - Dry Mouth, Xerostomia | Not applicable | Completed | SunBio, Inc. | 42 | 2022-05-02 | 2025-05-23 |
| Blinded Dry Mouth Spray Crossover Study Remineralizing Extreme Dry Mouth Spray with Xylitol, Alcohol-Free Moisturizing Dry Mouth Spray - Xerostomia, Head and Neck Cancer | Not applicable | Completed | Jonas Johnson | 129 | 2021-01-14 | 2024-02-01 |
| Duration of Effect of Biotene Spray in Patients With Dry Mouth Biotene, Placebo - Dry Mouth | Not applicable | Completed | University of Rochester | 37 | 2019-02-11 | 2021-01-20 |
| Use of Biotene Moisturizing Mouth Spray for Xerostomia Associated With Oral Oxybutynin Use Biotene oral spray - Overactive Bladder, Xerostomia | Phase 4 | Withdrawn | University of Southern California | 2018-08-01 | 2018-07-12 | |
| Caphosol Study: Prevention of Oral Mucositis in Children, Adolescents and Young Adults Receiving Chemotherapy Caphosol, Biotene - Oral Mucositis | Phase 3 | Terminated | Medical College of Wisconsin | 1 | 2016-10-01 | 2020-03-09 |
| A New Oral salIvary equivAlent Compared to Two moisturizinG Mouth sprAys in Patients With xeRostomiA: NIAGARA Study Salivary equivalent, Aequasyal, Biotene - Xerostomia, Hyposalivation | Phase 4 | Completed | Unither Pharmaceuticals, France | 210 | 2012-01-01 | 2014-01-29 |
| Mouth Care Regimes During Radiotherapy Biotene (mouth care) - Head and Neck Neoplasms | Phase 4 | Completed | St George Hospital, Australia | 50 | 1999-11-01 | 2005-12-15 |
Xerostomia (6) · Head and Neck Neoplasms (3) · Mucositis (1) · Neoplasms (1) · Patient Compliance (1) · Sjogren's Syndrome (1) · Stomatitis (1) · Urinary Bladder, Overactive (1)
Jonas Johnson (1) · Medical College of Wisconsin (1) · St George Hospital, Australia (1) · SunBio, Inc. (1) · Unither Pharmaceuticals, France (1) · University of Rochester (1) · University of Southern California (1)
United States (4) · Australia (1) · France (1)
Christina Dancz (1) · Jonas T Johnson, MD (1) · Michael E Burke, MD (1)
PMID 10435146, PMID 10775736, PMID 15712851, PMID 21532512, PMID 21684773, PMID 33602603