67 completed, 28 unknown, 9 recruiting, 9 terminated. 133 Phase 2, 19 Phase 1, 13 Phase 3.
Follow Stomatitis: new trials by email Literature Review of Stomatitis trials Research Report on Stomatitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Photobiomodulation Alone Versus Photobiomodulation Combined With Topical Oral Oxygen Therapy for Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized Clinical Trial sirolase xtent laser, blue m gel - Mucositis Oral, Head & Neck Cancer | Phase 1 / Phase 2 | Enrolling by invitation | Assiut University | 46 | 2026-08-15 | 2026-10-08 |
| Protective Role of Alpha-Lipoic Acid in Chemotherapy-Induced Mucositis alpha lipoic acid 600 mg twice daily, Placebo Tablet - Colorectal Cancer | Phase 2 / Phase 3 | Recruiting | Ain Shams University | 50 | 2026-07-27 | 2026-07-30 |
| Taurine for the Prevention and Treatment of Radiation-induced Oral Mucositis in Patients With Nasopharyngeal Carcinoma Taurine - Oral Mucositis (Ulcerative) Due to Radiation, Nasopharyngeal Carcinoma (NPC) | Phase 2 | Recruiting | Sun Yat-sen University | 130 | 2026-05-08 | 2026-10-30 |
| Study of a Copaiba-Based Mouthwash Combined With Low-Level Laser Therapy in the Prevention of Oral Mucositis in Patients Undergoing Hematopoietic Stem Cell Transplantation Copaíba, Placebo - Oral Mucositis, Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy | Phase 2 | Recruiting | Instituto Nacional de Cancer, Brazil | 76 | 2026-03-29 | 2026-09-09 |
| Amimestrocel Injection for Preventing Severe Oral Mucositis in HSCT Patients Amimestrocel injection - Oral Mucositis, Stomatitis | Phase 2 | Recruiting | The First Affiliated Hospital of Soochow University | 22 | 2026-02-15 | 2026-04-14 |
| Aerosolized Mesenchymal Stem Cell-Derived Exosomes for the Prevention and Treatment of Radiation-Induced Oral Mucositis mesenchymal stem cell-derived exosomes - Oral Mucositis (Ulcerative) Due to Radiation | Phase 2 | Not yet recruiting | First Affiliated Hospital of Guangxi Medical University | 200 | 2026-01-01 | 2025-12-31 |
| Safety and Efficacy Trial of TV5M01 for Radiation-Induced Mucositis in Head and Neck Cancer Patients. Green Tea Extract with Morphine, Active Comparator: Triple Mixture Oral Rinse for Radiation-Induced Mucositis - Squamous Cell Carcinoma of the Head and Neck, Oral Mucositis | Phase 1 / Phase 2 | Not yet recruiting | Fundacion Clinica Valle del Lili | 40 | 2025-12-28 | 2025-04-01 |
| Photobiomodulation for the Prevention of Oral Mucositis Photobiomodulation - INTRAORAL, Photobiomodulation - EXTRAORAL, Photobiomodulation - INTRAORAL and EXTRAORAL - Oral Mucositis | Phase 2 | Active not recruiting | Brigham and Women's Hospital | 78 | 2025-12-01 | 2025-12-18 |
| New Therapeutic Target for Toxic Epidermal Necrolysis (TEN) Using Anti-CD38+ Monoclonal Antibodies. DARATUMUMAB (DARZALEX®) - Toxic Epidermal Necrolysis, Immunotherapy | Phase 1 / Phase 2 | Not yet recruiting | Hospices Civils de Lyon | 9 | 2025-10-29 | 2025-08-07 |
| Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer Best Practice, Biospecimen Collection, Cisplatin - Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Phase 2 | Recruiting | NRG Oncology | 98 | 2025-06-23 | 2026-08-17 |
| Autologous Serum Obtained by a Closed-Circuit Collection Device Autologous Serum 20% - GVHD, Meibomian Gland Dysfunction (Disorder) | Phase 2 | Active not recruiting | GIANCARLO FATOBENE | 16 | 2025-06-20 | 2026-10-21 |
| Effect of Topical Bromelain Versus Topical Corticosteroids in the Management of Recurrent Aphthous Stomatitis 35% Topical Bromelain in Orabase, 50% Topical Bromelain in Orabase, 0.1% Topical Triamcinolone Acetonide in Orabase - Recurrent Aphthous Stomatitis | Phase 2 | Not yet recruiting | Cairo University | 63 | 2025-06-15 | 2025-05-28 |
| Effect of Arginine- and Glutamine-based Oral Formulations on Salivary Biomarkers and Clinical Severity of Radiation-induced Oral Mucositis in Head and Neck Cancer: A Randomized Controlled Trial L-arginine Oral Suspension, L-glutamine Oral Suspension, Maltodextrin Oral Suspension (Control) - Radiation Induced Oral Mucositis, Oral Mucositis | Phase 2 | Completed | Ain Shams University | 84 | 2025-04-01 | 2026-01-30 |
| Copaíba-based Mouthwash in Oral Mucotitis Prevention and Treatment in Oral Cancer Patients During Radioteraphy Copaíba mouthwash, Placebo mouthwash - Oral Mucositis, Oral Mucositis (Ulcerative) Due to Radiation | Phase 2 | Withdrawn | Instituto Nacional de Cancer, Brazil | 2025-01-17 | 2026-10-09 | |
| Pre-Radiotherapy n-6/n-3 Fatty Acid Ratio Predicts Severe Oral Mucositis in Nasopharyngeal Carcinoma Toripalimab (240mg day1, Q3W*3cycle), Cisplatin (80 mg/m2), Nab-paclitaxel - Nasopharyngeal Carcinoma (NPC), Radiation-induced Oral Mucositis | Phase 2 | Completed | Affiliated Hospital of Guangdong Medical University | 210 | 2024-11-01 | 2026-11-05 |
| Chlorophyllin for Reducing Oral Mucositis in Total Body Irradiation Prior to Transplant Sodium Copper Chlorophyllin - Oral Mucositis, Total Body Irradiation | Phase 2 | Recruiting | Tata Memorial Centre | 17 | 2024-10-30 | 2026-07-27 |
| Mucoadhesive Film With/without Acmella Oleracea & Triamcinolone Acetonide for Aphthous Ulcers mucoadhesive film with Acmella oleracea extract, Triamcinolone Acetonide 0.1% Oromucosal Paste, mucoadhesive film without Acmella oleracea extract - Aphthous Stomatitis | Phase 2 | Unknown | Khon Kaen University | 72 | 2024-10-15 | 2024-10-02 |
| Efficacy and Safety of Acyclovir-penciclovir Cream Versus an Abreva in the Suppression of Herpes Simplex Virus Eruptions acyclovir-penciclovir cream, Abreva - Herpes Simplex Oral | Phase 2 | Completed | University of Utah | 58 | 2024-08-19 | 2026-10-27 |
| LYell SYndrome MEsenchymal Stromal Cells Treatment Adipose derived stromal cells intravenously injected - Epidermal Necrolysis, Lyell Syndrome | Phase 1 / Phase 2 | Recruiting | Assistance Publique - Hôpitaux de Paris | 15 | 2024-04-15 | 2025-08-01 |
| Efficacy of N-acetylcysteine in Preventing Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer Patients. N-Acetyl-Cysteine with Institutional standard care, Institutional standard care - Oral Mucositis (Ulcerative) Due to Radiation | Phase 2 | Recruiting | Mansoura University | 50 | 2024-04-04 | 2025-01-15 |
Showing 20 of 133. Sign in to see all of them.
Head and Neck Neoplasms (25) · Mucositis (20) · Stomatitis, Aphthous (17) · Stevens-Johnson Syndrome (12) · Neoplasms (10) · Ulcer (10) · Oral Ulcer (9) · Nasopharyngeal Carcinoma (8) · Squamous Cell Carcinoma of Head and Neck (8) · Inflammation (5) · Stomatitis, Herpetic (5) · Mouth Diseases (4) · Stomatitis, Denture (4) · Carcinoma, Squamous Cell (3)
Stomatognathic Diseases (132) · Mouth Diseases (129) · Neoplasms by Site (43) · Neoplasms (42) · Digestive System Diseases (22) · Gastrointestinal Diseases (22) · Gastroenteritis (19) · Pathological Conditions, Signs and Symptoms (19) · Skin Diseases (19) · Skin and Connective Tissue Diseases (19) · Immune System Diseases (17) · Neoplasms by Histologic Type (17) · Pathologic Processes (17) · Neoplasms, Glandular and Epithelial (14)
Cisplatin (7) · Fibroblast Growth Factor 7 (5) · Radiotherapy, Intensity-Modulated (5) · Diphenhydramine (3) · Infliximab (3) · Injections (3) · Saline Solution (3) · Standard of Care (3) · Triamcinolone Acetonide (3) · Anti-Inflammatory Agents (2) · Ascorbic Acid (2) · Benzydamine (2) · Drug Therapy (2) · FGF20 protein, human (2) · Gentamicins (2)
Ain Shams University (3) · Cairo University (3) · Chang Gung Memorial Hospital (3) · Hadassah Medical Organization (3) · Kerman University of Medical Sciences (3) · M.D. Anderson Cancer Center (3) · Qazvin University Of Medical Sciences (3) · West China Hospital (3) · Beech Tree Labs, Inc. (2) · CuraGen Corporation (2) · EpicentRx, Inc. (2) · Galera Therapeutics, Inc. (2) · Hams Hamed Abdelrahman (2) · Hospices Civils de Lyon (2) · Instituto Nacional de Cancer, Brazil (2)
United States (48) · China (12) · Egypt (10) · France (7) · Canada (6) · Germany (6) · Iran (6) · Brazil (5) · India (5) · Spain (5) · Israel (4) · Italy (3) · Puerto Rico (3) · South Korea (3) · Belgium (2)
Christopher M Hull, M.D. (2) · Israel Rios, MD (2) · James Chodosh, MD, MPH (2) · Rakefet Czerninski, DMD (2) · Xingchen Peng (2) · Alan Joslyn, Ph.D. (1) · Alicia Lozano, MD (1) · Amr M Elkhouli, ass prof (1) · Andy M Trotti, MD (1) · Andy Trotti, MD (1) · Anet Tanic, DDS (1) · Arvind Chaudhry, MD,PhD (1)
PMID 18973181, PMID 35142535, PMID 35435039, PMID 11013273, PMID 11240232, PMID 12692611, PMID 13411920, PMID 15057287, PMID 15064010, PMID 15108222, PMID 15110092, PMID 15159012, PMID 15287078, PMID 15602019, PMID 16004814, PMID 16415901, PMID 16616780, PMID 16884839, PMID 16950583, PMID 17507164, PMID 18164921, PMID 18407446, PMID 18413833, PMID 18468541, PMID 18485252, PMID 18500368, PMID 19203728, PMID 19733615, PMID 20668585, PMID 20855800, PMID 21460603, PMID 21741230, PMID 21864666, PMID 22114446, PMID 22923859, PMID 22987094, PMID 23000649, PMID 23046006, PMID 23052923, PMID 23334484, PMID 23469127, PMID 23685937, PMID 24114811, PMID 24311846, PMID 24471119, PMID 24607557, PMID 24914142, PMID 25052044, PMID 25151488, PMID 25272640
2017 (1), D43DE032294 (1), K23DE016946 (1), R21CA158530 (1), UG1CA189867 (1)