32 completed, 10 unknown, 6 recruiting, 3 not yet recruiting. 19 Not applicable, 16 Phase 2, 8 Phase 3, 6 Phase 1, 3 Early Phase 1.
Follow Oral Ulcer: new trials by email Literature Review of Oral Ulcer trials Research Report on Oral Ulcer
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparing the Extent to Which Apremilast is Made Available in the Body After Administration as an Extended-release or Immediate-release Formulation Apremilast XR, Apremilast IR - Psoriasis, Arthritis, Psoriatic | Phase 1 | Not yet recruiting | Amgen | 114 | 2026-11-18 | 2026-11-02 |
| A Study of Phenytoin Mucoadhesive Film for Oral Ulcers in Healthy Volunteers 1% Phenytoin Mucoadhesive Film, Blank Mucoadhesive Film - Oral Ulcer, Oral Mucositis | Phase 1 | Not yet recruiting | Misr University for Science and Technology | 10 | 2026-10-20 | 2026-10-28 |
| Evaluation of Topical Rebamipide Versus Topical Betamethasone for Treatment of Oral Aphthous Ulcers Rebamipide mouthwash, Betamethasone mouthwash - Oral Aphthous Ulcers | Phase 2 | Recruiting | Cairo University | 46 | 2026-07-01 | 2026-10-06 |
| The Preventive and Therapeutic Effects of Spirulina Preparations on Ulcers of Oral Mucosa Spirulina Tablets, Placebo Tablets - Recurrent Aphthous Stomatitis, Mouth Ulcer | Not applicable | Recruiting | The Fourth Affiliated Hospital of Zhejiang University School of Medicine | 40 | 2026-06-01 | 2026-07-23 |
| Phase II Single Arm Open Label Study Evaluating the Feasibility and Safety of Photobiomodulation as an Adjunct to Standard Supportive Care for Chemotherapy Induced Oral Mucositis in Pediatric Patients With Hematolymphoid Malignancies Photobiomodulation Therapy - Oral Mucositis Due to Chemotherapy, Hematolymphoid Malignancies | Not applicable | Not yet recruiting | Tata Memorial Hospital | 46 | 2026-06-01 | 2026-05-22 |
| Observational Study of OROSEDAL in Sore Throat and Minor Oral Lesions OROSEDAL - Sore Throat, Aphthous Ulcer | Recruiting | Laboratoires Elerte | 124 | 2026-03-05 | 2026-06-02 | |
| Comparison of Hyaluronic Acid and Chlorhexidine Gels for Traumatic Oral Ulcers During Fixed Orthodontic Treatment Hyaluronic Acid gel, Chlorhexidine gel - Traumatic Oral Ulceration, Orthodontic Treatment | Not applicable | Completed | Dow University of Health Sciences | 30 | 2026-01-10 | 2026-07-16 |
| Effectiveness of Vitamin b12 Versus Kenalog on Traumatic Ulcer Associated With Orthodontic Treatment cyanocobalamin, triamcinolone acetonide - Mouth Ulcer | Not applicable | Completed | Hawraa Ali Abdullah | 82 | 2025-08-19 | 2026-03-03 |
| Mucoadhesive Film With/without Acmella Oleracea & Triamcinolone Acetonide for Aphthous Ulcers mucoadhesive film with Acmella oleracea extract, Triamcinolone Acetonide 0.1% Oromucosal Paste, mucoadhesive film without Acmella oleracea extract - Aphthous Stomatitis | Phase 2 | Unknown | Khon Kaen University | 72 | 2024-10-15 | 2024-10-02 |
| A Study on Sumac Mouth Rinse for Treating Recurrent Aphthous Stomatitis Sumac mouth rinse, Tantum Verde mouth rinse - Recurrent Aphthous Stomatitis | Not applicable | Completed | Ain Shams University | 38 | 2023-12-20 | 2026-05-08 |
| Clinical Efficiency of Natural Herbal Based Gel. Denpro oral gel - Oral Ulcer | Not applicable | Completed | Pakistan Institute of Medical Sciences | 202 | 2023-06-15 | 2024-09-19 |
| Lenalidomide in the Treatment of Mucosal Behçet's Syndrome Lenalidomide 10 mg - Oral Ulcer | Not applicable | Recruiting | Peking Union Medical College Hospital | 42 | 2023-04-01 | 2026-06-22 |
| A Study of Apremilast in Children With Oral Ulcers Associated With Behçet's Disease or Juvenile Psoriatic Arthritis Apremilast - Behçet's Disease, Juvenile Psoriatic Arthritis | Phase 3 | Recruiting | Amgen | 48 | 2023-03-23 | 2026-11-04 |
| Pilot Clinical Study Testing Tiger Milk Mushroom Gel (Lignosus Rhinocerus TM02®) for Treating Mouth Ulcers xLr oral gel, Placebo, Kanolone - Mouth Ulcer | Not applicable | Completed | Mahsa University | 21 | 2023-02-01 | 2025-05-15 |
| Comparison of the Effects of Oral Ulceration Healing in Patients Wearing a Removable Denture Chlorhexidine Gluconate, Choline Salicylate 8.7 % Oral Gel, control group - Oral Mucosa; Ulcer | Not applicable | Completed | Medical University of Silesia | 27 | 2023-01-01 | 2024-08-01 |
| Post-marketing Study for the Evaluation of Profilm Mouth Sores Profilm Mouth Sores - Mouth Sores | Not applicable | Completed | i+Med S.Coop. | 35 | 2022-12-13 | 2025-04-25 |
| Post-marketing Study for the Evaluation of Profilm Cold Sores Profilm Cold Sores - Cold Sores | Not applicable | Completed | i+Med S.Coop. | 35 | 2022-12-13 | 2025-04-01 |
| Therapeutic Effect of Folic Acid in Healing of Oral Ulcers Folic Acid 5 MG, placebo - Oral Ulcer | Early Phase 1 | Unknown | Dow University of Health Sciences | 75 | 2022-09-01 | 2022-03-24 |
| Study for the Prevention of Oral Mucositis (SPOM) Bocaliner, Benzydamine - Oral Mucositis | Phase 1 / Phase 2 | Unknown | E2Bio Life Sciences, LLC | 100 | 2022-04-15 | 2023-09-08 |
| Dose-ranging Study of Dentoxol® Mouthrinse for Managing Oral Symptoms in People With Epidermolysis Bullosa. Dentoxol mouthrinse dosages - Epidermolysis Bullosa, Oral Ulcer | Phase 2 | Unknown | University of Chile | 100 | 2022-04-06 | 2022-04-14 |
Showing 20 of 54. Sign in to see all of them.
Stomatitis (12) · Stomatitis, Aphthous (12) · Mucositis (6) · Behcet Syndrome (5) · Head and Neck Neoplasms (4) · Pain (3) · Carcinoma, Squamous Cell (2) · Constipation (2) · Foot-and-Mouth Disease (2) · Hemorrhoids (2) · Lichen Planus, Oral (2) · Mouth Diseases (2) · Oropharyngeal Neoplasms (2) · Pharyngitis (2)
Stomatognathic Diseases (54) · Mouth Diseases (52) · Skin Diseases (13) · Skin and Connective Tissue Diseases (13) · Stomatitis (11) · Digestive System Diseases (9) · Gastrointestinal Diseases (9) · Pathological Conditions, Signs and Symptoms (8) · Cardiovascular Diseases (7) · Gastroenteritis (7) · Infections (7) · Vascular Diseases (7) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (6) · Eye Diseases (6) · Genetic Diseases, Inborn (6)
Low-Level Light Therapy (3) · Triamcinolone Acetonide (3) · apremilast (3) · Anti-Inflammatory Agents (2) · Prednisolone (2) · chlorhexidine gluconate (2) · Adrenal Cortex Hormones (1) · Benzydamine (1) · Betamethasone (1) · Colchicine (1) · Control Groups (1) · Diet (1) · Drinking (1) · Fibroblast Growth Factor 7 (1) · Flavin Mononucleotide (1)
Amgen (3) · Cairo University (3) · Dow University of Health Sciences (2) · i+Med S.Coop. (2) · Ain Shams University (1) · Al-Azhar University (1) · Assiut University (1) · Beni-Suef University (1) · Chang Gung Memorial Hospital (1) · Chulalongkorn University (1) · E2Bio Life Sciences, LLC (1) · Galera Therapeutics, Inc. (1) · HaEmek Medical Center, Israel (1) · Hadassah Medical Organization (1) · Hawraa Ali Abdullah (1)
United States (10) · Egypt (7) · Spain (7) · China (4) · Israel (4) · France (3) · Turkey (Türkiye) (3) · Canada (2) · Greece (2) · Italy (2) · Pakistan (2) · Puerto Rico (2) · Armenia (1) · Chile (1) · Colombia (1)
Afsheen Mansoor, Ph.D (1) · Andy Trotti, MD (1) · Anners Lerdal, PhD (1) · Beatriz E Marciano, M.D. (1) · Cennet N Eroglu, DDS,PhD (1) · Dan Miron, MD (1) · Davide Sisti, PhD (1) · Donald Welsh, MD (1) · Doug Peterson, DMD (1) · Galit Avior, MD (1) · Gene Kennedy, MD (1) · Guy Juillard, MD (1)
PMID 12411880, PMID 15501961, PMID 20187965, PMID 22186854, PMID 25126527, PMID 26401826, PMID 26436049, PMID 2736897, PMID 31618127, PMID 31664632, PMID 32820431, PMID 32893718, PMID 33586003, PMID 34145168, PMID 34212234, PMID 3471374, PMID 3514243, PMID 37072843, PMID 40045332, PMID 40268883, PMID 40742572, PMID 41127563, PMID 41185016, PMID 6587971
2023 (2), D43DE032294 (1)