224 completed, 83 recruiting, 53 unknown, 17 active not recruiting. 424 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 424 | Completed 224, Recruiting 83, Unknown 53, Active not recruiting 17, Not yet recruiting 17, Enrolling by invitation 10, Withdrawn 10, Terminated 9, Suspended 1 |
Follow Speech Disorders: new trials by email Literature Review of Speech Disorders trials Research Report on Speech Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lateral Cord Stimulation as a New Treatment for Refractory Spastic Cerebral Palsy Lateral spinal cord surgical implant of electrodes - Cerebral Palsy, Spasticity | Not applicable | Not yet recruiting | Juan Carlos M. Andreani MD | 40 | 2027-06-01 | 2026-04-28 |
| Combined Intervention Program for Non-fluent Aphasia Based on Neuroplasticity CIPAN = MIT + CIAT, MIT + MIT, CIAT + CIAT - Non-fluent Aphasia | Not applicable | Not yet recruiting | Universidad de Granada | 48 | 2027-01-01 | 2026-08-14 |
| Deep Brain Stimulation + Therapy for Stroke Boston Scientific Vercise Deep Brain Stimulation (DBS) System, Rehabilitation Training Protocol - Stroke, Dysarthria | Not applicable | Not yet recruiting | Pirondini, Elvira, PhD | 15 | 2027-01-01 | 2026-09-30 |
| Listen Aphasia Pilot Study LISTEN (AI-based AAC smartphone app) - Aphasia, Malignant Brain Tumor | Not applicable | Not yet recruiting | Dana-Farber Cancer Institute | 80 | 2027-01-01 | 2026-07-28 |
| Functional Reorganization and Recovery of the Language and Domain-general Multiple Demand Systems in Aphasia Constant Therapy program - Aphasia | Not applicable | Recruiting | Boston University Charles River Campus | 100 | 2026-12-01 | 2026-11-10 |
| Cerebellar Brain Stimulation Plus Language Therapy for People at Risk of Poor Aphasia Recovery After Stroke Cathodal cerebellar transcranial direct current stimulation, Computerized language therapy - Aphasia, Stroke | Not applicable | Not yet recruiting | Johns Hopkins University | 8 | 2026-11-01 | 2026-11-03 |
| BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Aphasia (BG-Aphasia-01) BrainGate Neural Interface System - Expressive Aphasia, Aphasia Following Cerebral Infarction | Not applicable | Not yet recruiting | Leigh R. Hochberg, MD, PhD. | 5 | 2026-11-01 | 2026-11-06 |
| Restoring Speech With an Intracortical Neuroprosthesis for Post-Stroke Agrammatic Aphasia (BG-Aphasia-02) BrainGate Neural Interface System - Aphasia, ALS | Not applicable | Not yet recruiting | Leigh R. Hochberg, MD, PhD. | 2 | 2026-10-31 | 2026-11-05 |
| Effectiveness of Virtually Simulated Intervention for Patients Having Stuttering Virtually Simulated Intervention, Traditional Speech Therapy - Stuttering | Not applicable | Not yet recruiting | Riphah International University | 44 | 2026-10-25 | 2026-11-05 |
| Effects of Semantic Context on Criterion-learning Naming Treatment in Aphasia Criterion-learning practice - Aphasia | Not applicable | Enrolling by invitation | Albert Einstein Healthcare Network | 12 | 2026-10-20 | 2026-10-28 |
| Evaluation of the Feasibility and Efficacy of a Chronic Brain-computer Interface for Speech Rehabilitation in Patients With Locked-in-syndrome (LIS) Chronic speech BCI - Locked in Syndrome, ALS (Amyotrophic Lateral Sclerosis) | Not applicable | Not yet recruiting | University Hospital, Grenoble | 3 | 2026-10-10 | 2026-07-13 |
| Development and Pilot Testing of Virtually Simulated Intervention for Patients Having Stuttering Virtually Simulated Intervention - Stuttering | Not applicable | Not yet recruiting | Riphah International University | 10 | 2026-09-10 | 2026-09-22 |
| Study of Cognitive-Linguistic Profiles: The Role of Executive Control in Aphasia Neuropsychological tests, Speech-language assessments - Stroke | Not applicable | Not yet recruiting | University Hospital, Toulouse | 30 | 2026-09-01 | 2026-08-14 |
| Wireless Implantable Mandarin Chinese Speech Neuroprosthesis Evaluation WRS - Speech Disorder | Not applicable | Recruiting | Shanghai StairMed Technology Co., Ltd. | 4 | 2026-09-01 | 2026-09-11 |
| Noninvasive Thalamocortical Neuromodulation With Low-Intensity Focused Ultrasound for Persistent Developmental Stuttering High DC LIFU, Sham - Stuttering, Developmental Stuttering | Not applicable | Recruiting | University of Michigan | 20 | 2026-08-19 | 2026-09-15 |
| Desensitization-Based Structured Intervention Program for Individuals With Stuttering Structured Desensitization-Based Job Interview Program - Stuttering | Not applicable | Recruiting | DİLARA BASER | 36 | 2026-07-20 | 2026-08-14 |
| Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech Unpredictable auditory feedback perturbation: 2 behavioral sessions, Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions, Sustained F1 auditory feedback perturbation - Stuttering, Developmental, Dyslexia | Not applicable | Recruiting | Boston University Charles River Campus | 90 | 2026-06-12 | 2026-07-21 |
| Stimulating the Aging Brain Using Brain and Sensory Stimulation tACS or multisensory stimulation - Primary Progressive Aphasia | Not applicable | Recruiting | Medical College of Wisconsin | 20 | 2026-06-01 | 2026-06-16 |
| Recovery From Post-Stroke Aphasia With rTMS Targeting Left or Right Anterior Temporal Lobe continuous Theta Burst Stimulation, intermittent Theta Burst Stimulation, Transcranial Magnetic Stimulation Sham - Stroke, Aphasia | Not applicable | Recruiting | University of South Carolina | 45 | 2026-05-15 | 2026-05-29 |
| Targeted Transcranial Magnetic Stimulation to Improve Language and Speech in Patients With Primary Progressive Aphasia Training with Speech Language Therapy, Standard rTMS, Targeted rTMS - Primary Progressive Aphasia(PPA) | Not applicable | Enrolling by invitation | IRCCS San Raffaele | 75 | 2026-05-13 | 2026-05-20 |
Showing 20 of 424. Sign in to see all of them.
Aphasia (247) · Stroke (145) · Aphasia, Primary Progressive (47) · Stuttering (45) · Communication Disorders (43) · Dysarthria (43) · Language (28) · Anomia (27) · Aphasia, Broca (24) · Language Disorders (23) · Parkinson Disease (22) · Speech (22) · Frontotemporal Dementia (20) · Apraxias (14)
Neurobehavioral Manifestations (424) · Neurologic Manifestations (424) · Pathological Conditions, Signs and Symptoms (424) · Signs and Symptoms (424) · Nervous System Diseases (423) · Language Disorders (401) · Communication Disorders (381) · Central Nervous System Diseases (239) · Brain Diseases (235) · Cardiovascular Diseases (158) · Cerebrovascular Disorders (158) · Vascular Diseases (158) · Mental Disorders (128) · Behavior (73)
Transcranial Direct Current Stimulation (39) · Speech Therapy (21) · Transcranial Magnetic Stimulation (16) · Language Therapy (9) · Therapeutics (4) · Control Groups (3) · Exercise (3) · Blood Specimen Collection (2) · Cognitive Behavioral Therapy (2) · Deep Brain Stimulation (2) · Drug Delivery Systems (2) · Music Therapy (2) · Standard of Care (2) · 4-deethylatrazine (1) · Acupuncture Therapy (1)
VA Office of Research and Development (16) · Johns Hopkins University (10) · Medical College of Wisconsin (9) · Riphah International University (9) · Changping Laboratory (8) · Shirley Ryan AbilityLab (8) · Boston University Charles River Campus (7) · University of Michigan (7) · University of Pennsylvania (6) · Albert Einstein Healthcare Network (5) · The Hong Kong Polytechnic University (5) · University of Chicago (5) · Karolinska Institutet (4) · Leigh R. Hochberg, MD, PhD. (4) · Stanford University (4)
United States (207) · France (19) · United Kingdom (19) · Canada (17) · Pakistan (17) · China (15) · Germany (11) · Italy (9) · Hong Kong (8) · Sweden (8) · Turkey (Türkiye) (8) · Spain (7) · Switzerland (7) · South Korea (6) · Belgium (5)
Hesheng Liu, PhD (6) · Kyrana Tsapkini, PhD (4) · Maya L Henry, PhD (4) · Amy D. Rodriguez, PhD (3) · Julie L Wambaugh, PhD (3) · Leora Cherney, PhD (3) · Min Ney Wong, PhD (3) · Priyanka Shah-Basak, PhD (3) · Soo-Eun Chang, PhD (3) · Aneta Kielar, PhD (2) · Carolyn I Rodriguez, MD, PhD (2) · Diane L. Kendall, PhD (2) · Dylan Edwards, Ph.D. (2) · E. Susan Duncan, PhD, CCC-SLP (2) · Engy S Elhakeem, PhD (2)
PMID 10350414, PMID 10568646, PMID 10796360, PMID 10990547, PMID 11556941, PMID 11849307, PMID 14502069, PMID 15087552, PMID 16635494, PMID 16737714, PMID 17030751, PMID 17900904, PMID 19158063, PMID 19453637, PMID 20040569, PMID 21233468, PMID 21825004, PMID 21842404, PMID 22215032, PMID 23050517, PMID 23071199, PMID 23108446, PMID 23613966, PMID 23695900, PMID 23695909, PMID 23695913, PMID 23799617, PMID 23828834, PMID 23933108, PMID 24059983, PMID 24166562, PMID 24687207, PMID 24961525, PMID 25075917, PMID 25378426, PMID 25658635, PMID 25929694, PMID 26133692, PMID 26384102, PMID 26635571, PMID 26926872, PMID 27053642, PMID 27063676, PMID 27445970, PMID 27506677, PMID 27856480, PMID 27867260, PMID 27997948, PMID 28084854, PMID 28093560
R01AG055425 (3), R01DC015516 (3), 2016 (2), P50DC014664 (2), 1DP2DC021055 (1), 2019 (1), 2023 (1), DP2DC024816 (1), F31DC020352 (1), I01RX000832 (1), I21RX002566 (1), K23DC021744 (1), K23MH092434 (1), K99DC023302 (1), P20GM109089 (1)