25 unknown. 25 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 25 | Unknown 25 |
Follow Shock: new trials by email Literature Review of Shock trials Research Report on Shock
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oral Bedtime Melatonin in Critically Ill Patients Oral Bedtime Melatonin, Placebo suspension or capsule - Septic Shock, Stroke Hemorrhagic | Phase 4 | Unknown | Hospital San Carlos, Madrid | 160 | 2025-02-01 | 2024-03-01 |
| Renal Outcomes in the Early Use of Vasopressin in the Treatment of Septic Shock vasopressin infusion when the norepinephrine dosage is equal to or greater than 0.25 mcg/kg/min, vasopressin infusion when the norepinephrine dosage is equal to or greater than 0.5 mcg/kg/min - Septic Shock, Renal Function Replacement | Phase 4 | Unknown | Azienda Usl di Bologna | 264 | 2024-05-15 | 2024-06-24 |
| Efficacy of the Use of Vasopressin as a Primary Vasoconstrictor in Critically Ill Patients Initiation of vasopressine as a first vasoconstrictive drug, Initiation of noradrenaline as a first vasoconstrictive drug - Circulatory Shock | Phase 4 | Unknown | University of Thessaly | 145 | 2023-12-15 | 2024-03-06 |
| Hemodynamic Response to Angiotensin-II When Used as the Second Vasopressor Agent for Septic Shock Angiotensin II and hydrocortisone sodium succinate - Septic Shock, Shock | Phase 4 | Unknown | Kingman Regional Medical Center | 50 | 2023-12-04 | 2024-05-23 |
| The Construction and Application of Therapeutic System of Intelligent Decision-Oriented Hemodynamic Organized Therapy for Shock Patients norepinephrine+vasopressin, Norepinephrine - Septic Shock | Phase 4 | Unknown | Peking Union Medical College Hospital | 60 | 2023-05-01 | 2023-06-02 |
| Role of Ulinastatin in Preventing Severe Sepsis and Consequent Morbidities and Mortality Ulinastatin - Severe Sepsis, Septic Shock | Phase 4 | Unknown | Jinnah Postgraduate Medical Centre | 175 | 2023-05-01 | 2023-06-08 |
| Cytokine Guided Risk Stratification and Treatment in Pediatric Hemophagocytic Lymphohistiocytosis Dexamethasone, Etoposide, Ruxolitinib - Hemophagocytic Lymphohistiocytoses, Cytokine Storm | Phase 4 | Unknown | The Children's Hospital of Zhejiang University School of Medicine | 400 | 2022-09-01 | 2022-10-06 |
| 20% Albumin vs. Balanced Salt Solution as Resuscitation Fluid in Cirrhosis With Sepsis Induced Hypotension 20% albumin, Balanced salt solution - Cirrhosis, Liver, Acute-On-Chronic Liver Failure | Phase 4 | Unknown | Post Graduate Institute of Medical Education and Research, Chandigarh | 150 | 2020-08-15 | 2022-07-01 |
| Low-chlorine Vs High-chlorine Crystalloids in Septic Shock Adults Sodium Bicarbonate Ringer's Injection, 0.9% Sodium Chloride Injection - Septic Shock | Phase 4 | Unknown | Southeast University, China | 100 | 2020-05-01 | 2020-04-28 |
| The Use of Tocilizumab in the Management of Patients Who Have Severe COVID-19 With Suspected Pulmonary Hyperinflammation Tocilizumab - Covid19 Pneumonia | Phase 4 | Unknown | Hadassah Medical Organization | 500 | 2020-04-08 | 2020-05-06 |
| Evaluation of Early Association of Terlipressin and Norepinephrine During Septic Shock; the TerliNor Study Terlipressin, Placebo - Septic Shock | Phase 4 | Unknown | Assistance Publique Hopitaux De Marseille | 40 | 2018-07-27 | 2018-11-29 |
| Efficacy and Safety on Heart Rate Control With Ivabradine on Cardiogenic Shock Ivabradine Oral Tablet, Standard of Care treatment - Cardiogenic Shock | Phase 4 | Unknown | Hospital Universitario Ramon y Cajal | 22 | 2018-05-01 | 2018-02-19 |
| Effect of Ivabradine in Stage D HF/Cardiogenic Shock Patients on Dobutamine Ivabradine, Placebo - Heart Failure, Cardiogenic Shock | Phase 4 | Unknown | Loyola University | 40 | 2018-03-15 | 2019-05-23 |
| Dex on Microcirculation in SS-A Double-blinded Study Dexmedetomidine for dexmedetomidine group - Septic Shock | Phase 4 | Unknown | Southeast University, China | 44 | 2016-01-01 | 2017-06-15 |
| Effects of Levosimendan, Milrinone and Norepinephrine on Left and Right Ventricular Function in Septic Shock Norepinephrine, Milrinone, Levosimendan - Septic Shock, Cardiomyopathy | Phase 4 | Unknown | Sahlgrenska University Hospital | 30 | 2015-12-01 | 2018-11-29 |
| Early Goal Directed Sedation on Microcirculation in Septic Shock Dexmedetomidine for sedation - Septic Shock | Phase 4 | Unknown | Southeast University, China | 25 | 2015-11-01 | 2016-04-20 |
| The Pharmacokinetics of Fentanyl in Intensive Care Patients Fentanyl - Multiple Organ Failure, Critical Care | Phase 4 | Unknown | Oslo University Hospital | 150 | 2015-10-01 | 2015-10-29 |
| Botulinum Toxin A for Treatment of Catocholamine Induced Finger Necrosis Botox, Placebo - Catocholamine Induced Finger Necrosis | Phase 4 | Unknown | Sheba Medical Center | 20 | 2012-01-01 | 2012-01-05 |
| Chloride High Level Of Resuscitation Infusion Chloride High Level Of Resuscitation Infusion Delivered Evaluation Lower chloride fluids (Hartmann's solution and Plasmalyte®) - Shock, Critical Illness | Phase 4 | Unknown | Austin Health | 7000 | 2009-02-01 | 2010-02-25 |
| Early Continuous Renal Replacement Therapies (CRRT) in Patients With Severe Sepsis or Septic Shock With Acute Kidney Injury crrt - Severe Sepsis, Septic Shock | Phase 4 | Unknown | Asan Medical Center | 60 | 2009-02-01 | 2009-02-05 |
Showing 20 of 25. Sign in to see all of them.
Shock, Septic (14) · Diabetes Insipidus (4) · Multiple Organ Failure (4) · Sepsis (4) · Cytokine Release Syndrome (2) · Shock, Cardiogenic (2) · Systemic Inflammatory Response Syndrome (2) · Acidosis (1) · Acute Kidney Injury (1) · Acute-On-Chronic Liver Failure (1) · Cardiomyopathies (1) · Critical Illness (1) · Heart Arrest (1) · Heart Failure (1)
Pathologic Processes (25) · Pathological Conditions, Signs and Symptoms (25) · Inflammation (17) · Systemic Inflammatory Response Syndrome (15) · Infections (14) · Sepsis (10) · Cardiovascular Diseases (5) · Female Urogenital Diseases (5) · Female Urogenital Diseases and Pregnancy Complications (5) · Heart Diseases (5) · Kidney Diseases (5) · Male Urogenital Diseases (5) · Urogenital Diseases (5) · Urologic Diseases (5)
Norepinephrine (4) · Dexmedetomidine (2) · Ivabradine (2) · Adrenal Cortex Hormones (1) · Albumins (1) · Angiotensin II (1) · Botulinum Toxins, Type A (1) · Capsules (1) · Ceftriaxone (1) · Continuous Renal Replacement Therapy (1) · Control Groups (1) · Dexamethasone (1) · Drug and Narcotic Control (1) · Etoposide (1) · Fentanyl (1)
Southeast University, China (3) · Asan Medical Center (1) · Assistance Publique Hopitaux De Marseille (1) · Association Pour La Promotion A Tours De La Reanimation Medicale (1) · Austin Health (1) · Azienda Usl di Bologna (1) · Hadassah Medical Organization (1) · Hospital San Carlos, Madrid (1) · Hospital Universitario Principe de Asturias (1) · Hospital Universitario Ramon y Cajal (1) · Jinnah Postgraduate Medical Centre (1) · Kingman Regional Medical Center (1) · Loyola University (1) · Medical University of Vienna (1) · Oslo University Hospital (1)
China (4) · France (2) · Israel (2) · Spain (2) · United States (2) · Australia (1) · Austria (1) · Brazil (1) · Canada (1) · Greece (1) · India (1) · Italy (1) · Norway (1) · Pakistan (1) · South Korea (1)
Amir Herman, MD, PhD (1) · Eugenia Raichlin, MD (1) · Juli Benbenisty, MPH (1) · Kevin Teoh, MD, MSc (1) · Miguel Sanchez, MD, PhD (1) · Nor'azim Mohd Yunos, MBBS (1) · Peter Schenk, MD (1) · Richard P Whitlock, MD, MSc (1) · Salim Yusuf, MD, DPhil (1) · Sven-Erik Ricksten, Professor (1) · Tom Heier, Professor (1) · Tyson Dietrich, PharmD (1)
PMID 12794416, PMID 18305265, PMID 21545483, PMID 21705897, PMID 23073953, PMID 24794878, PMID 25004265, PMID 26460660, PMID 27483065, PMID 28666990, PMID 28820036, PMID 29600824, PMID 30833491, PMID 34605781, PMID 36018257, PMID 36416787
2008 (1), 2017 (1)