Safety: Clinical Trials

224 trials for Safety, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

117 completed, 50 unknown, 23 recruiting, 14 not yet recruiting. 93 Phase 1, 51 Not applicable, 38 Phase 2, 16 Phase 3, 15 Phase 4.

By phase and status

PhaseTrialsStatus
Phase 193Completed 60, Recruiting 12, Unknown 9, Terminated 5, Not yet recruiting 4, Withdrawn 2, Enrolling by invitation 1
Not applicable51Completed 26, Unknown 17, Not yet recruiting 3, Recruiting 3, Suspended 1, Terminated 1
Phase 238Completed 14, Unknown 11, Recruiting 5, Not yet recruiting 3, Active not recruiting 2, Terminated 2, Enrolling by invitation 1
Phase 316Completed 7, Unknown 5, Active not recruiting 2, Recruiting 2
Phase 415Unknown 8, Completed 6, Not yet recruiting 1
Early Phase 13Completed 1, Recruiting 1, Terminated 1

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Efficacy of iPSC-Derived Motor Neuron Cells (XS228) in Subacute Spinal Cord Injury: A Phase II Randomized Controlled Trial
Allogeneic Human Induced Pluripotent Stem Cell (iPSC)-Derived Motor Neuron Progenitor Cells, Placebo - Spinal Cord Injury, Safety
Phase 2Not yet recruitingXellSmart Bio-Pharmaceutical (Suzhou) Co., Ltd.602028-05-252025-11-25
A First-in-Human SAD and MAD Study in Healthy Participants to Evaluate Oral YR011 Tablet
Kv1.3 potassium channel blocker (PA032, investigational oral small-molecule drug), Placebo - Safety, Tolerability
Phase 1Not yet recruitingHangzhou Yirui Pharmaceutical Technology Co., Ltd642027-04-012026-07-30
A First-in-Human SAD and MAD Study in HV to Evaluate Oral YR011 Tablet
Kv1.3 potassium channel blocker (PA032, investigational oral small-molecule drug), Placebo - Safety, Tolerability
Phase 1Not yet recruitingHangzhou Yirui Pharmaceutical Technology Co., Ltd642027-01-012026-10-16
To Evaluate the Safety and Efficacy of Hemay5394 in Patients With Mild to Moderate Atopic Dermatitis
Hemay5394 group, Control group - Safety, Efficiency
Phase 2Not yet recruitingHemay Pharmaceutical PTY. LTD.902026-11-012026-10-16
Evaluating a Shared Decision-making Intervention for Families About Firearm Storage
Family Safety Check-In, AAP Resource - Safety
Not applicableNot yet recruitingSeattle Children's Hospital5482026-10-012026-04-16
Phase 1/2 Clinical Study of HY07121 for Injection (Subcutaneous) in Patients With Advanced Solid Tumors
Test Product HY07121 for Injection (Subcutaneous) - Safety, Tolerability
Phase 1 / Phase 2Not yet recruitingSichuan Huiyu Pharmaceutical Co., Ltd2542026-09-082026-08-27
A Randomized, Multicenter, Open-label, Active-controlled Phase Ib Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of Multiple Intravaginal Doses of GenSci142 in Patients With Bacterial Vaginosis (BV)
GenSci142 capsule, clindamycin phosphate vaginal cream - Randomized, Open-label
Phase 1RecruitingChangchun GeneScience Pharmaceutical Co., Ltd.422026-08-152026-10-15
Evaluation of Allergenicity by HRIPT and Phototest
Blancy Pro - Safety
Not applicableCompletedBrainfarma Industria QuĂ­mica e FarmacĂȘutica S/A552026-07-132026-09-16
Tamsulosin Monotherapy Versus Combination Therapy With Tadalafil (2.5 mg vs 5 mg) in Managing Male LUTS Secondary to BPH
Tamsulosin 0.4 mg + Tadalafil 2.5 mg, Tamsulosin 0.4 mg + Tadalafil 5 mg, Tamsulosin 0.4 mg - Safety, Efficacy
Not applicableRecruitingAin Shams University902026-07-012026-07-23
Short-Term Safety and Performance of Two Wound Dressings Evaluation
Politix Fiber arm - Chronic Wound Care, Local Infection
Not applicableNot yet recruitingSebastian Probst602026-06-152026-05-08
Evaluation of a Sexual Violence and Intimate Partner Violence Primary Prevention Program Implemented in Drinking Establishments
Safe Night Out Program, No Safe Night Out - Intimate Partner Violence (IPV), Sexual Violence
Not yet recruitingUniversity of California, San Diego6502026-06-012026-02-27
The Relationship Between Nurses' Perception Of Safety Culture And Patients' Sense Of Safety
Nursing Personnel, Safety
Not yet recruitingUludag University2062026-05-012026-05-07
Safety and Efficacy of Psilocybin-assisted Psychotherapy for Demoralization Syndrome in Patients Diagnosed With Advanced Stage Cancer
Psilocybin-assisted Psychotherapy - Demoralization, Safety
Phase 1RecruitingGustavo Vazquez152026-04-012026-03-18
Safety and Tolerability of IRL757 in Participants With Parkinson's Disease and Apathy
IRL757, Placebo - PARKINSON DISEASE (Disorder), Apathy
Phase 1 / Phase 2RecruitingIntegrative Research Laboratories AB752026-02-182026-09-03
Safety Exploration and Evaluation of Dexmedetomidine Hydrochloride Nasal Spray for Pre-anesthesia Sedation in Low-Monitoring Settings
Dexmedetomidine hydrochloride nasal spray, Placebo - Dexmedetomidine, Sedation
Phase 4Not yet recruitingSichuan Provincial People's Hospital5642026-01-102025-12-23
Study in Healthy Subjects to Investigate the Relative Bioavailability and Safety of Pasireotide After Single Subcutaneous Dose Administration Using a Reusable ServoPen With Cartridge as Compared to Administration Using a Syringe Drawn From an Ampule
Pasireotide cartridge with reusable ServoPen, Pasireotide ampule with syringe - Pharmacokinetics, Safety
Phase 1CompletedRECORDATI GROUP402025-12-012026-02-04
A Study of GensSci098 in Subjects With Graves' Disease
GenSci098 - Safety, Tolerability
Phase 1RecruitingChangchun GeneScience Pharmaceutical Co., Ltd.242025-11-212026-02-17
A Study to Learn More About Prevenar 20 Once it is Out in the Korean Market
Pneumococcal 20-valent conjugate vaccine - Pneumococcal Immunization, Safety
RecruitingPfizer6602025-11-132026-03-12
Safety and Efficacy of Papillary Versus NonPapillary Access During Percutaneous Nephrolithotomy
Papillary access puncture, Non-papillary access puncture - Safety, Efficacy
Not applicableRecruitingAin Shams University702025-11-012026-10-02
Evaluation of the Efficacy and Safety of Megestrol Acetate in Preventing Nausea and Vomiting Induced by Highly Emetogenic Chemotherapy
Low dose of Megestrol Acetate Oral Suspension combined with standard therapy, Medium dose of Megestrol Acetate Oral Suspension combined with standard therapy, High dose of Megestrol Acetate Oral Suspension combined with standard therapy - Efficacy, Safety
Phase 1Not yet recruitingChangchun GeneScience Pharmaceutical Co., Ltd.1322025-09-292025-08-19

Showing 20 of 224. Sign in to see all of them.

Narrower conditions

COVID-19 (5)  ·  Alzheimer Disease (3)  ·  Heart Failure (3)  ·  Respiratory Aspiration (3)  ·  Spinal Cord Injuries (3)  ·  Stroke (3)  ·  Arthritis, Rheumatoid (2)  ·  Breast Neoplasms (2)  ·  Colorectal Neoplasms (2)  ·  Drug-Related Side Effects and Adverse Reactions (2)  ·  Influenza, Human (2)  ·  Lung Diseases, Interstitial (2)  ·  Marijuana Abuse (2)  ·  Mpox, Monkeypox (2)  ·  Psychological Well-Being (2)

Broader conditions

Pathological Conditions, Signs and Symptoms (17)  ·  Respiratory Tract Diseases (15)  ·  Neoplasms (14)  ·  Pathologic Processes (14)  ·  Nervous System Diseases (13)  ·  Infections (12)  ·  Central Nervous System Diseases (11)  ·  Neoplasms by Site (11)  ·  Cardiovascular Diseases (10)  ·  Urogenital Diseases (10)  ·  Virus Diseases (10)  ·  Brain Diseases (9)  ·  Immune System Diseases (9)  ·  Lung Diseases (9)  ·  Endocrine System Diseases (8)

Interventions

Control Groups (3)  ·  Influenza Vaccines (3)  ·  AZD9977 (2)  ·  Bevacizumab (2)  ·  Deoxycholic Acid (2)  ·  GV-971 (2)  ·  Injections (2)  ·  Midazolam (2)  ·  Morphine (2)  ·  Radiosurgery (2)  ·  Safety (2)  ·  Suspensions (2)  ·  microcrystalline cellulose (2)  ·  velsecorat (2)  ·  ((3-methoxythiophen-2-yl)methyl)((2-(9-(pyridin-2-yl)-6-oxaspiro(4.5)decan-9-yl)ethyl))amine (1)

Sponsors

AstraZeneca (12)  ·  Pfizer (8)  ·  Changchun GeneScience Pharmaceutical Co., Ltd. (5)  ·  Ain Shams University (3)  ·  MicuRx (3)  ·  Sichuan Huiyu Pharmaceutical Co., Ltd (3)  ·  Stemirna Therapeutics (3)  ·  Tanta University (3)  ·  The Affiliated Hospital of Qingdao University (3)  ·  Anhui Provincial Hospital (2)  ·  Astellas Pharma Europe B.V. (2)  ·  CannaXan GmbH (2)  ·  Duke University (2)  ·  First Affiliated Hospital Xi'an Jiaotong University (2)  ·  Galderma R&D (2)

Countries

China (51)  ·  United States (43)  ·  United Kingdom (15)  ·  Germany (13)  ·  Canada (9)  ·  Egypt (8)  ·  Spain (8)  ·  South Korea (7)  ·  France (6)  ·  Sweden (6)  ·  Denmark (5)  ·  Poland (5)  ·  Australia (4)  ·  Belgium (4)  ·  Bulgaria (4)

Top investigators

Katherine Bunge, MD (3)  ·  Mayfong Mayxay, doctor (3)  ·  Sharon L Hillier, PhD (3)  ·  Abdelrahman G Salman, MD (2)  ·  Frederick Beddingfield, III, MD, PhD (2)  ·  Julia Solnier, PhD (2)  ·  Limin Rong, prof and M.D (2)  ·  Yi Han, doctorate (2)  ·  Aaron Samuels, MD (1)  ·  Adrianne C. Feldstein, MD, MS (1)  ·  Alberto Torres Zamudio, MD (1)  ·  Ali R Djalilian, MD (1)  ·  Alice Mannocci (1)  ·  Andrea Ludwig-Sengpiel, Dr. (1)

Results publications

PMID 12750546, PMID 16019852, PMID 17000941, PMID 17110769, PMID 18470620, PMID 19219697, PMID 20921468, PMID 21791539, PMID 22397650, PMID 22966018, PMID 23352749, PMID 24071851, PMID 24732979, PMID 25109877, PMID 25176015, PMID 25243564, PMID 25326492, PMID 25780077, PMID 26342236, PMID 26873727, PMID 27162549, PMID 27477896, PMID 27853199, PMID 27902652, PMID 28390780, PMID 29504252, PMID 29557719, PMID 30121146, PMID 30244209, PMID 30741494, PMID 30777086, PMID 30855740, PMID 30855741, PMID 30985861, PMID 31424503, PMID 31601801, PMID 32033600, PMID 32087818, PMID 32171764, PMID 32673497, PMID 32715381, PMID 32853681, PMID 33148815, PMID 33538338, PMID 33736819, PMID 34428445, PMID 34447992, PMID 34487721, PMID 34890373, PMID 35142858

NIH funding

2015 (4), 2009 (2), 2017 (2), 2018 (2), U19AI120249 (2), 2014 (1), 2019 (1), P30CA047904 (1), R01HD102402 (1), R44AG067907 (1), U01CE003735 (1), U01HL125388 (1), U01HL126088 (1)