5 completed, 3 recruiting. 3 Phase 1, 2 Phase 2, 2 Phase 4, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 2 | Completed 2 |
| Phase 4 | 2 | Recruiting 2 |
| Phase 3 | 1 | Recruiting 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Short-term Bactericidal Effect of Contezolid in MAC-PD Contezolid, Azithromcyin, Rifampicin (RIF) - Mycobacterium Avium Complex Pulmonary Disease | Phase 4 | Recruiting | Bin Cao | 188 | 2025-07-24 | 2025-09-18 |
| Short-term Antibiotic Therapy in Mycobacterium Avium Complex Pulmonary Disease Contezolid, Azithromycin, Ethambutol (E) - Mycobacterium Avium Complex Pulmonary Disease | Phase 4 | Recruiting | Bin Cao | 188 | 2025-07-24 | 2025-10-09 |
| Safety and Efficacy Study of Contezolid Acefosamil and Contezolid Compared to Linezolid Administered Intravenously and Orally to Adults With Moderate or Severe Diabetic Foot Infections (DFI) contezolid acefosamil (IV)/contezolid (PO), Linezolid (IV and PO) - Diabetic Foot Infection | Phase 3 | Recruiting | MicuRx | 865 | 2022-05-03 | 2026-10-13 |
| Study of the Safety, Tolerability, and PK of MRX-8 Administered Intravenously to HVs in SAD and MAD Cohorts MRX-8, Placebo - Safety | Phase 1 | Completed | MicuRx | 69 | 2020-11-29 | 2023-08-24 |
| Contezolid Acefosamil Versus Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infection contezolid acefosamil, linezolid 600 mg - Skin Diseases, Bacterial, Gram-Positive Bacterial Infections | Phase 2 | Completed | MicuRx | 196 | 2018-11-15 | 2022-11-08 |
| Single Dose Escalation and Multiple Dose Escalation Trial of an Intravenous Formulation of MRX-4 Single intravenous doses of MRX-4, Single intravenous doses of placebo, Multiple intravenous doses of MRX-4 - Safety | Phase 1 | Completed | MicuRx | 90 | 2016-10-01 | 2018-03-22 |
| Single Dose and Multiple Dose Escalation Trial of an Oral Formulation of MRX-4 Oral single doses of MRX-4, Oral multiple doses of MRX-4, MRX-4 co-administered with omeprazole - Safety | Phase 1 | Completed | MicuRx | 122 | 2016-08-02 | 2023-11-09 |
| MRX-I Versus Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infection MRX-I, Linezolid - Bacterial Infections | Phase 2 | Completed | MicuRx | 120 | 2015-02-01 | 2024-11-04 |
Bacterial Infections (1) · Gram-Positive Bacterial Infections (1) · Skin Diseases, Bacterial (1)
Linezolid (3) · Ethambutol (2) · Rifampin (2) · contezolid (2) · Azithromycin (1) · Omeprazole (1)
United States (3) · China (2) · Bulgaria (1) · Estonia (1) · Georgia (1) · Italy (1) · Latvia (1) · Poland (1) · Serbia (1)
Xiaojin Cui, M.D. (1) · Xiaojing Cui, M.D. (1)