8 unknown, 6 completed, 1 not yet recruiting. 15 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 15 | Unknown 8, Completed 6, Not yet recruiting 1 |
Follow Safety: new trials by email Literature Review of Safety trials Research Report on Safety
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety Exploration and Evaluation of Dexmedetomidine Hydrochloride Nasal Spray for Pre-anesthesia Sedation in Low-Monitoring Settings Dexmedetomidine hydrochloride nasal spray, Placebo - Dexmedetomidine, Sedation | Phase 4 | Not yet recruiting | Sichuan Provincial People's Hospital | 564 | 2026-01-10 | 2025-12-23 |
| Simultaneous mRNA COVID-19 and IIV Vaccination in Pregnancy Study mRNA COVID-19 vaccine, IIV4 (quadrivalent inactivated influenza vaccine) - Birth Outcomes, Safety | Phase 4 | Completed | Duke University | 98 | 2024-09-12 | 2026-10-07 |
| Immunogenicity and Safety of Concomitant Administration of Bivalent COVID-19 Vaccines With Influenza Vaccines bivalent BNT162b2 mRNA original/omicron BA.4-5 vaccine, quadrivalent influenza vaccine - Immune Response, Safety | Phase 4 | Completed | Catholic Kwandong University | 154 | 2022-10-12 | 2024-03-26 |
| Remimazolam Improves the Safety in Elderly Patients Undergoing Gastrointestinal Endoscopy Remimazolam, Propofol group - Anesthetics, Recovery | Phase 4 | Unknown | First Affiliated Hospital Xi'an Jiaotong University | 300 | 2022-07-10 | 2022-07-01 |
| Efficacy and Safety of Memantine and Sodium Oligomannate in Patients With Moderate to Severe Alzheimer's Disease Memantine Oral Tablet, GV-971 capsule - Treatment, Efficacy | Phase 4 | Unknown | First Affiliated Hospital Xi'an Jiaotong University | 150 | 2022-07-01 | 2022-07-07 |
| Combined Immunization of COVID-19 Inactivated Vaccine With QIV and PPV23 Vaccine - Safety, Immunogenicity, Vaccine | Phase 4 | Unknown | Centers for Disease Control and Prevention, China | 3000 | 2021-10-08 | 2022-03-28 |
| Nalbuphine Versus Morphine for Perioperative Tumor Ablation Nalbuphine, Morphine - Nalbuphine Allergy, Ablation | Phase 4 | Unknown | Zhongda Hospital | 316 | 2021-09-05 | 2022-12-29 |
| Tenofovir Alafenamide to Prevent Perinatal Transmission of Hepatitis B Tenofovir Alafenamide fumarate 25mg Oral Tablet - Chronic Hepatitis B, Mother-to-Child Transmission | Phase 4 | Unknown | The First Affiliated Hospital of Zhengzhou University | 240 | 2021-04-26 | 2021-04-23 |
| Safety and Efficacy of Sodium Bicarbonate Ringer Injection sodium bicarbonate Ringer injection, Lactated Ringer's solution - Ringer Bicarbonate, Elderly Abdominal Surgery | Phase 4 | Unknown | Chinese PLA General Hospital | 5000 | 2020-10-01 | 2020-10-22 |
| Safety of RIV4 Versus IIV4 in Pregnant Women Quadrivalent Recombinant Influenza Vaccine, Quadrivalent Inactivated Influenza Vaccine - Safety, Adverse Event Following Immunisation | Phase 4 | Completed | Duke University | 384 | 2019-09-05 | 2023-01-11 |
| Evaluating QTc, PK, Safety of Gemtuzumab Ozogamicin (GO) in Patients With CD33+ R/R AML Gemtuzumab Ozogamicin - ECG, Pharmacokinetics | Phase 4 | Completed | Pfizer | 51 | 2019-07-03 | 2022-03-25 |
| RDD Versus VDD in Newly Diagnosed Patients With Multiple Myeloma RDD, VDD - Hematologic Neoplasms, Multiple Myeloma | Phase 4 | Unknown | Shandong Provincial Hospital | 120 | 2019-03-30 | 2019-11-29 |
| Nurse Administered Propofol Sedation vs. Midazolam With Fentanyl-sedation for Flexible Bronchoscopy: A Randomized, Single Blind, Controlled Study of Satisfaction and Safety. Propofol sedation, Midazolam and Fentanyl sedation - Flexible Bronchoscopy, Sedation | Phase 4 | Unknown | Copenhagen University Hospital at Herlev | 128 | 2014-11-01 | 2015-06-30 |
| Study Evaluating a 13-valent Pneumococcal Conjugate Vaccine in Preterm Compared to Term Infants. 13-valent pneumococcal conjugate vaccine - 13-valent Pneumococcal Vaccine, Premature Birth | Phase 4 | Completed | Pfizer | 200 | 2010-10-01 | 2017-05-11 |
| FDA Phase IV - Commitment - Retinal Function Study Sildenafil, Placebo, Vardenafil (Levitra, BAY38-9456) - Safety | Phase 4 | Completed | Bayer | 63 | 2005-02-01 | 2015-03-19 |
Influenza, Human (2) · Alzheimer Disease (1) · Hematologic Neoplasms (1) · Hepatitis B (1) · Hepatitis B, Chronic (1) · Multiple Myeloma (1) · Personal Satisfaction (1) · Premature Birth (1)
Infections (3) · Virus Diseases (3) · Orthomyxoviridae Infections (2) · RNA Virus Infections (2) · Respiratory Tract Diseases (2) · Respiratory Tract Infections (2) · Behavior (1) · Blood Protein Disorders (1) · Blood-Borne Infections (1) · Brain Diseases (1) · Cardiovascular Diseases (1) · Central Nervous System Diseases (1) · Chronic Disease (1) · Communicable Diseases (1) · DNA Virus Infections (1)
Influenza Vaccines (3) · CVnCoV COVID-19 vaccine (1) · Fentanyl (1) · FluLaval (1) · GV-971 (1) · Gemtuzumab (1) · Memantine (1) · Midazolam (1) · Morphine (1) · Nalbuphine (1) · Ringer's Lactate (1) · Sildenafil Citrate (1) · Tablets (1) · Vaccines (1) · Vardenafil Dihydrochloride (1)
Duke University (2) · First Affiliated Hospital Xi'an Jiaotong University (2) · Pfizer (2) · Bayer (1) · Catholic Kwandong University (1) · Centers for Disease Control and Prevention, China (1) · Chinese PLA General Hospital (1) · Copenhagen University Hospital at Herlev (1) · Shandong Provincial Hospital (1) · Sichuan Provincial People's Hospital (1) · The First Affiliated Hospital of Zhengzhou University (1) · Zhongda Hospital (1)
China (4) · United States (3) · Poland (2) · Spain (2) · Canada (1) · Denmark (1) · Hungary (1) · South Korea (1) · United Kingdom (1)
Elizabeth Barnett, MD (1) · Elizabeth Schlaudecker, MD, MPH (1) · Gao-Jun Teng, MD (1) · Geeta K Swamy, MD (1) · Geeta Swamy, MD (1) · Karen R Broder, MD (1) · Matthew Crist, MD (1) · Matthew Zuber, MD (1) · Min Joo Choi, Doctor (1) · Paul F Clementsen, Professor (1) · Qiang Wang (1) · Qing-Lei Zeng (1) · Satoshi Kamidani, MD, PhD (1)
PMID 25780077, PMID 27902652, PMID 36273202, PMID 36892676, PMID 38140184, PMID 39229259, PMID 39382852
2009 (1), 2018 (1)