12 completed, 4 unknown, 3 terminated, 2 withdrawn. 22 Phase 3, 8 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 22 | Completed 12, Unknown 4, Terminated 3, Withdrawn 2, Recruiting 1 |
| Phase 2 | 8 | Completed 4, Recruiting 1, Terminated 1, Unknown 1, Withdrawn 1 |
Follow Rupture: new trials by email Literature Review of Rupture trials Research Report on Rupture
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase 3 Study of the Efficacy and Safety of MR Arthrography Using the NEMO-103 Injection in Patients With Known or Suspected Shoulder Joint Diseases NEMO-103 Injection - Rotator Cuff Tear, Labral Tear | Phase 3 | Completed | Inventera Inc. | 85 | 2025-09-23 | 2026-11-06 |
| Exploring the Feasibility of Silk Fibroin Surgical Mesh in Rotator Cuff Tears Repair Enhancement Silk fibroin surgical mesh - Rotator Cuff Tear | Phase 2 / Phase 3 | Recruiting | Weiliang Shen, Ph.D., M.D. | 20 | 2024-12-19 | 2025-01-09 |
| Analysis of the Effect of Neuromuscular Electro-stimulation on the Performance of Isometric Rotator Cuff Strength. STRENGTH EVALUATION WITH ELECTROSTIMULATOR, STRENGTH EVALUATION WITHOUT ELECTROSTIMULATOR - Rotator Cuff Impingement Syndrome, Rotator Cuff Tendinitis | Phase 2 / Phase 3 | Unknown | University of Campinas, Brazil | 60 | 2023-09-01 | 2023-09-05 |
| Efficacy and Safety of the Application of Local Anaesthetic in Spray to Repair of 1st- 2nd Perineal Lacerations Lidocaine Hydrochloride, Mepivacaine Injection - Vaginal Discharge, Perineum; Rupture | Phase 3 | Completed | Azienda Sanitaria-Universitaria Integrata di Udine | 136 | 2022-01-20 | 2023-09-21 |
| Can Testosterone Accelerate Injury Recovery After Arthroscopic Rotator Cuff Repair Testosterone cypionate, Placebos - Rotator Cuff Tears | Phase 2 / Phase 3 | Withdrawn | Orthopedic Institute, Sioux Falls, SD | 2021-08-01 | 2022-03-15 | |
| Does Tranexamic Acid Improve Visualization During Arthroscopic Rotator Cuff Repair Tranexamic Acid 100 MG/ML - Rotator Cuff Tears, Rotator Cuff Injuries | Phase 3 | Unknown | University of Saskatchewan | 50 | 2021-01-13 | 2021-05-03 |
| Use of Extended Release Triamcinolone in the Treatment of Rotator Cuff Disease FX006 Injection - Rotator Cuff Tears, Rotator Cuff Tendinitis | Phase 3 | Terminated | Northwell Health | 40 | 2020-08-27 | 2026-11-04 |
| The Impact of a Preoperative Nerve Block on the Consumption of Sevoflurane in Total Shoulder Arthroplasty Ropivacaine, Dextrose - Rotator Cuff Injuries, Anesthesia; Functional | Phase 2 / Phase 3 | Terminated | University of Alberta | 17 | 2019-08-01 | 2024-06-06 |
| The Impact of a Preoperative Nerve Block on the Consumption of Sevoflurane Ropivacaine, Normal saline - Rotator Cuff Injury, Anesthesia; Functional | Phase 2 / Phase 3 | Completed | University of Alberta | 27 | 2019-05-01 | 2022-05-24 |
| Liposomal Bupivacaine in Shoulder Arthroscopy Liposomal bupivacaine, Bupivacaine with Dexamethasone Solution - Rotator Cuff Tears | Phase 3 | Withdrawn | University of Pennsylvania | 2019-02-21 | 2024-03-12 | |
| Oral Ketorolac for Arthroscopic Rotator Cuff Repair Ketorolac - Rotator Cuff Tear, Postoperative Pain | Phase 3 | Completed | University Hospitals Cleveland Medical Center | 44 | 2019-02-11 | 2022-05-10 |
| Efficacy of Intra-articular NSAID Versus Corticosteroid in the Treatment of Shoulder and Knee Conditions: A Randomized, Double-Blind, Prospective Study Shoulder injection, knee injection - Knee Arthritis, Shoulder Arthritis | Phase 3 | Unknown | OSF Healthcare System | 50 | 2018-08-01 | 2018-08-06 |
| A Phase I/III Clinical Study of TPX-114 for the Treatment of Full-Thickness Rotator Cuff Tear TPX-114, Arthroscopic surgery - Rotator Cuff Injuries | Phase 3 | Completed | Tego Science, Inc. | 93 | 2018-07-09 | 2023-05-18 |
| Does Subacromial Injection With Glutamate Receptor Antagonist, Ketamine, Attenuate Pain in Rotator Cuff Tendinopathy? Ketalar, NaCl 9% - Rotator Cuff Tendinitis, Chronic Pain | Phase 2 / Phase 3 | Completed | Helse Møre og Romsdal HF | 14 | 2018-05-30 | 2025-08-22 |
| Buprenorphine Transdermal Patches in Arthroscopic Rotator Cuff Repair Buprenorphine, Placebo Patch, Multimodal Oral Scheme - Rotator Cuff Tear, Rotator Cuff Injury | Phase 2 / Phase 3 | Completed | Hospital Italiano de Buenos Aires | 50 | 2016-09-22 | 2021-04-08 |
| Study Comparing the Polyurethane Films and Sugarcane Biopolymer Used as Dressings Application of dressings for surgical correction., POLYSHAFT® - Wound, Rupture | Phase 3 | Completed | Polisa - Biopolímeros para Saúde | 141 | 2014-08-01 | 2015-08-25 |
| A Safety and Tolerability Study of Doripenem Compared With Meropenem in Children Hospitalized With Complicated Intra-abdominal Infections Doripenem, Meropenem placebo, Meropenem - Abscess, Intra-Abdominal, Abdominal Abscess | Phase 3 | Terminated | Janssen Research & Development, LLC | 41 | 2010-12-01 | 2014-07-15 |
| The Influence of Growth Factors (PDGF), Applied as Autologous Thrombocyte Concentrate, on Functional Recovery Platelet Rich Plasma - Rotator Cuff Rupture, Subacromial Impingement | Phase 3 | Completed | St. Antonius Hospital | 73 | 2010-07-01 | 2014-05-01 |
| Platelet Rich Plasma on Rotator Cuff Repair Platelet rich plasma - Rotator Cuff Tears | Phase 3 | Completed | University of Sao Paulo | 54 | 2008-09-01 | 2014-12-03 |
| Diclofenac Patch for Treatment of Mild to Moderate Tendonitis or Bursitis diclofenac sodium, Matching Placebo - Rotator Cuff Tendonitis, Bicipital Tendonitis | Phase 2 / Phase 3 | Completed | Cerimon Pharmaceuticals | 308 | 2007-12-01 | 2008-08-06 |
Showing 20 of 22. Sign in to see all of them.
Rotator Cuff Injuries (19) · Shoulder Impingement Syndrome (6) · Bursitis (2) · Shoulder Pain (2) · Tendinopathy (2) · Abdomen, Acute (1) · Abdominal Abscess (1) · Abdominal Pain (1) · Agnosia (1) · Appendicitis (1) · Chronic Pain (1) · Ileus (1) · Infections (1) · Intestinal Perforation (1)
Wounds and Injuries (21) · Shoulder Injuries (19) · Tendon Injuries (19) · Joint Diseases (9) · Musculoskeletal Diseases (9) · Neurologic Manifestations (6) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Pain (5) · Arthralgia (2) · Muscular Diseases (2) · Abscess (1) · Arthritis (1) · Cecal Diseases (1)
Ropivacaine (2) · Amoxicillin-Potassium Clavulanate Combination (1) · Arthroscopy (1) · Bupivacaine (1) · Buprenorphine (1) · Diclofenac (1) · Doripenem (1) · FX006 (1) · Glucose (1) · Ketamine (1) · Ketorolac (1) · Lidocaine (1) · Mepivacaine (1) · Meropenem (1) · Saline Solution (1)
University of Alberta (2) · Azienda Sanitaria-Universitaria Integrata di Udine (1) · Cerimon Pharmaceuticals (1) · Helse Møre og Romsdal HF (1) · Hospital Italiano de Buenos Aires (1) · Inventera Inc. (1) · Janssen Research & Development, LLC (1) · McMaster University (1) · Northwell Health (1) · OSF Healthcare System (1) · Orthopedic Institute, Sioux Falls, SD (1) · Polisa - Biopolímeros para Saúde (1) · St. Antonius Hospital (1) · Tego Science, Inc. (1) · University Hospitals Cleveland Medical Center (1)
United States (6) · Canada (5) · Brazil (3) · Argentina (2) · South Korea (2) · Chile (1) · China (1) · Colombia (1) · Italy (1) · Latvia (1) · Lithuania (1) · Netherlands (1) · Norway (1) · Panama (1)
Rakesh V Sondekoppam, MD (2) · Vivian HY Ip, MD (2) · Arnaldo A Ferreira Neto, PhD (1) · Dan Levitt, MD (1) · Eduardo A Malavolta, MD (1) · Jacco Zijl, drs (1) · Jeremy Reed, MD (1) · Joo Han Oh (1) · Joy C MacDermid, PhD (1) · Keith M Baumgarten, MD (1) · Kevin Willits, MD, FRCS(C) (1) · Lora Pencheva, MD (1) · Lorenza Driul, professor (1)
PMID 23849573, PMID 29664865, PMID 30234999, PMID 34524031, PMID 38914976
2009 (1)