8 recruiting, 2 not yet recruiting, 1 active not recruiting, 1 enrolling by invitation. 7 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Recruiting 6, Not yet recruiting 1 |
Follow REM Sleep Behavior Disorder (iRBD): new trials by email Literature Review of REM Sleep Behavior Disorder (iRBD) trials Research Report on REM Sleep Behavior Disorder (iRBD)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Artificial Intelligence-based Parkinson's Disease Risk Assessment (AI-PRA) Study Smartwatch and phone app - Parkinson Disease (PD), REM Sleep Behavior Disorder (iRBD) | Not yet recruiting | Queen Mary University of London | 60 | 2026-10-01 | 2026-10-02 | |
| Understanding Alpha-Synuclein Spread in Parkinson's Disease Through Blood Biomarkers and Neuroimaging brain imaging, blood draw, Skin biopsy - Parkinson's Disease (PD), GBA1 Parkinson Disease | Not applicable | Not yet recruiting | University of Pavia | 160 | 2026-05-11 | 2026-05-01 |
| Pain Assessment in Patients With Idiopathic Rapid Eye Movement (REM) Sleep Behaviour Disorder Thermo test pain, Pain questionnaires, No motors symptoms evaluations - REM Sleep Behavior Disorder (iRBD), Narcolepsy Type 1 | Not applicable | Recruiting | University Hospital, Toulouse | 24 | 2026-02-24 | 2026-05-01 |
| Ultra-High Resolution PET in Aging, Neurodegeneration and Psychotic Disorders UHR PET/CT scan of the brain with ¹⁸F-FDG, UHR PET/CT scan of the brain with ¹⁸F-PE2I, UHR PET/CT scan of the brain with ¹⁸F-SynVesT-1 - Alzheimer Dementia (AD), ALS - Amyotrophic Lateral Sclerosis | Not applicable | Recruiting | Universitaire Ziekenhuizen KU Leuven | 300 | 2026-02-13 | 2026-04-03 |
| Role of Slow Waves in the Progression of Neurodegeneration in Isolated REM Sleep Behavior Disorder Tosoo Axora - Parkinson Disease, REM Sleep Behavior Disorder (iRBD) | Not applicable | Recruiting | University of Zurich | 80 | 2026-01-15 | 2026-02-17 |
| Development and Online Evaluation of an Online Course for Parasomnias Parasomnia Education, Sleep Hygiene Control - Sleep Terror, Sleepwalking | Not applicable | Recruiting | University of Manitoba | 20 | 2025-11-14 | 2026-01-23 |
| The Role of METhanogens in the PROgression Of Parkinson's Disease and Related Neurological Conditions Probiotic Supplementation with L. reuteri - PARKINSON DISEASE (Disorder), Parkinson | Not applicable | Recruiting | University of Cambridge | 215 | 2025-11-01 | 2026-08-25 |
| Study of Sleep Disorders in Prodromal and Definite Parkinsons Disease Polysomnography - Parkinson Disease, REM Sleep Behavior Disorder (iRBD) | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 457 | 2025-03-18 | 2026-03-06 |
| Prodromal Model of Parkinson's Disease Confined to The Peripheral Nervous System Polyneuropathy, Alpha-Synucleinopathy | Enrolling by invitation | University of Aarhus | 100 | 2024-05-13 | 2025-01-08 | |
| The Syn-Sleep Study Syn-One Test - REM Sleep Behavior Disorder (iRBD) | Active not recruiting | CND Life Sciences | 80 | 2022-09-15 | 2025-01-15 | |
| Molecular Imaging of Inflammation in Parkinson's Disease Using LPS and TSPO-PET/MR Lipopolysaccharide, PET/MR with [11C]PBR28 - Neurodegenerative Diseases, Parkinson Disease | Recruiting | University of Exeter | 30 | 2022-02-28 | 2025-10-07 | |
| The Swedish BioFINDER Sleep Study Dopamine transporter PET scan with [18F]FE-PE2I, Magnetic resonance imaging (MRI), [123I] MIBG scintigraphy of the heart - Parkinson´s Disease, REM Sleep Behavior Disorder (iRBD) | Recruiting | Skane University Hospital | 650 | 2021-10-01 | 2026-04-16 |
REM Sleep Behavior Disorder (12) · Parkinson Disease (9) · Lewy Body Disease (3) · Alzheimer Disease (2) · Dementia (2) · Disease (2) · Multiple System Atrophy (2) · Synucleinopathies (2) · Amyotrophic Lateral Sclerosis (1) · Anosmia (1) · Cognitive Dysfunction (1) · Constipation (1) · Inflammation (1) · Mitochondrial Diseases (1) · Nerve Degeneration (1)
Mental Disorders (12) · Nervous System Diseases (12) · Parasomnias (12) · REM Sleep Parasomnias (12) · Sleep Wake Disorders (12) · Basal Ganglia Diseases (9) · Brain Diseases (9) · Central Nervous System Diseases (9) · Movement Disorders (9) · Parkinsonian Disorders (9) · Neurodegenerative Diseases (8) · Pathological Conditions, Signs and Symptoms (7) · Synucleinopathies (7) · Metabolic Diseases (4) · Neurocognitive Disorders (4)
Blood Specimen Collection (2) · (methyl-(11)C)N-acetyl-N-(2-methoxybenzyl)-2-phenoxy-5-pyridinamine (1) · Biological Factors (1) · Defecation (1) · Lipopolysaccharides (1) · Magnetic Resonance Imaging (1) · Neuroimaging (1) · Polysomnography (1) · Urination (1)
Assistance Publique - Hôpitaux de Paris (1) · CND Life Sciences (1) · Queen Mary University of London (1) · Skane University Hospital (1) · Universitaire Ziekenhuizen KU Leuven (1) · University Hospital, Toulouse (1) · University of Aarhus (1) · University of Cambridge (1) · University of Exeter (1) · University of Manitoba (1) · University of Pavia (1) · University of Zurich (1)
France (3) · United Kingdom (3) · Belgium (1) · Canada (1) · Denmark (1) · Italy (1) · Spain (1) · Sweden (1) · Switzerland (1) · United States (1)
Andreas Luft, Prof. Dr. med. (1) · Astrid J. Terkelsen, MD, DrMedSc, PhD, Professor (1) · Caroline Williams-Gray, Dr. (1) · Erik Stomrud, MD, PhD (1) · Marios Politis, MD MSc PhD (1) · Marta Camacho, Dr. (1) · Norah Vincent, PhD (1) · Todd Levine (1)