2 active not recruiting, 2 not yet recruiting, 2 recruiting, 1 completed. 3 Not applicable, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Active not recruiting 1, Not yet recruiting 1, Recruiting 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Digital Health Technologies for Progressive Supranuclear Palsy and Dementia With Lewy Bodies Progressive Supranuclear Palsy(PSP), Dementia With Lewy Bodies (DLB) | Not yet recruiting | BioSensics | 60 | 2027-01-15 | 2026-10-13 | |
| Intraoperative Bupivacaine Injection to Reduce Acute and Chronic Pain After TVT/TVT-O Surgery. Randomized Double-Blind Trial Bupivacain (Postoperative), Placebo - Pain After Surgery, PSP | Not applicable | Not yet recruiting | Hadassah Medical Organization | 60 | 2026-07-01 | 2026-06-23 |
| Repetitive Transcranial Magnetic Stimulation in Frontotemporal Lobar Degeneration Theta burst stimulation, Sham Theta burst stimulation - FTLD, FTD | Not applicable | Recruiting | Università degli Studi di Brescia | 120 | 2025-02-13 | 2026-01-05 |
| The CurePSP Genetics Program Whole genome sequencing will be performed at the NIH - PSP, PSP - Progressive Supranuclear Palsy | Recruiting | Massachusetts General Hospital | 1000 | 2024-10-08 | 2026-01-14 | |
| AMX0035 and Progressive Supranuclear Palsy AMX0035, Placebo - Progressive Supranuclear Palsy, PSP | Phase 2 / Phase 3 | Completed | Amylyx Pharmaceuticals Inc. | 139 | 2023-12-21 | 2026-04-30 |
| Integrated Management of Atypical Parkinsonism: A Home-based Patient-Centered Healthcare Delivery Based on Telenursing (IMPACT Study) Telemonitoring, Standard-of-care - Atypical Parkinsonism, MSA - Multiple System Atrophy | Not applicable | Active not recruiting | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 164 | 2023-08-17 | 2026-03-27 |
| A Multi-Modal Remote Monitoring Platform for Frontotemporal Lobar Degeneration (FTLD) Syndromes PAMSys, LEGSys - PSP, CBD | Active not recruiting | Massachusetts General Hospital | 60 | 2023-07-28 | 2026-01-21 | |
| Clinico-Pathologic-Genetic-Imaging Study of Neurodegenerative and Related Disorders C-11 PiB, AV1451 Tau, C-11 ER176 - PSP, CBD | Enrolling by invitation | Mayo Clinic | 500 | 2020-11-01 | 2025-11-21 |
Supranuclear Palsy, Progressive (4) · Shy-Drager Syndrome (3) · Corticobasal Degeneration (2) · Frontotemporal Dementia (2) · Frontotemporal Lobar Degeneration (2) · Aphasia (1) · Apraxias (1) · Lewy Body Disease (1) · Multiple System Atrophy (1) · Multiple system atrophy (MSA) with orthostatic hypotension (1) · Neurodegenerative Diseases (1) · Pain (1) · Parkinson Disease (1) · Pick Disease of the Brain (1)
Brain Diseases (7) · Central Nervous System Diseases (7) · Nervous System Diseases (7) · Basal Ganglia Diseases (6) · Movement Disorders (6) · Neurologic Manifestations (6) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Neurodegenerative Diseases (5) · Cranial Nerve Diseases (4) · Dementia (4) · Eye Diseases (4) · Mental Disorders (4) · Neurocognitive Disorders (4) · Ocular Motility Disorders (4)
2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole (1) · Postoperative Period (1) · Standard of Care (1) · sodium phenylbutyrate and taurursodiol (1)
Massachusetts General Hospital (2) · Amylyx Pharmaceuticals Inc. (1) · BioSensics (1) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (1) · Hadassah Medical Organization (1) · Mayo Clinic (1) · Università degli Studi di Brescia (1)
United States (5) · Italy (3) · France (1) · Germany (1) · Spain (1)
1UF1AG094587-01 (1)