2 completed, 2 recruiting. 1 Early Phase 1, 1 Not applicable, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 1 | Completed 1 |
| Not applicable | 1 | Recruiting 1 |
| Phase 2 | 1 | Completed 1 |
Follow Multiple system atrophy (MSA) with orthostatic hypotension: new trials by email Literature Review of Multiple system atrophy (MSA) with orthostatic hypotension trials Research Report on Multiple system atrophy (MSA) with orthostatic hypotension
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Epidural Electrical Stimulation to Support Hemodynamic Management in Individuals With Parkinson's Disease ARC-IM Investigational System - Hypotension Symptomatic, Parkinson's Disease | Not applicable | Recruiting | Ecole Polytechnique Fédérale de Lausanne | 5 | 2025-07-03 | 2026-07-07 |
| The CurePSP Genetics Program Whole genome sequencing will be performed at the NIH - PSP, PSP - Progressive Supranuclear Palsy | Recruiting | Massachusetts General Hospital | 1000 | 2024-10-08 | 2026-01-14 | |
| Effect of Verdiperstat on Microglial Activation in Well-characterized MSA Patients [F-18]PBR06, Verdiperstat - Multiple System Atrophy, Multiple System Atrophy, Cerebellar Variant | Early Phase 1 | Completed | Brigham and Women's Hospital | 19 | 2020-12-30 | 2022-08-19 |
| TD-9855 Phase 2 in Neurogenic Orthostatic Hypotension (nOH) TD-9855, Placebo - Neurogenic Orthostatic Hypotension, Multiple System Atrophy (MSA) With Orthostatic Hypotension | Phase 2 | Completed | Theravance Biopharma | 34 | 2017-09-09 | 2022-09-26 |
Multiple System Atrophy (3) · Hypotension, Orthostatic (2) · Parkinson Disease (2) · Pure Autonomic Failure (2) · Shy-Drager Syndrome (2) · Corticobasal Degeneration (1) · Hypotension (1) · Supranuclear Palsy, Progressive (1)
Autonomic Nervous System Diseases (4) · Basal Ganglia Diseases (4) · Brain Diseases (4) · Central Nervous System Diseases (4) · Movement Disorders (4) · Nervous System Diseases (4) · Neurodegenerative Diseases (4) · Primary Dysautonomias (4) · Synucleinopathies (4) · Cardiovascular Diseases (3) · Vascular Diseases (3) · Hypotension (2) · Orthostatic Intolerance (2) · Parkinsonian Disorders (2) · Cranial Nerve Diseases (1)
ampreloxetine (1)
Brigham and Women's Hospital (1) · Ecole Polytechnique Fédérale de Lausanne (1) · Massachusetts General Hospital (1) · Theravance Biopharma (1)
United States (3) · Switzerland (1)
Jocelyne Bloch, MD (1) · Tarun Singhal, MD (1) · Vikram Khurana, MD, PhD (1)