19 completed, 12 unknown, 5 not yet recruiting, 3 recruiting. 15 Not applicable, 7 Phase 4, 3 Phase 3, 2 Phase 1, 1 Early Phase 1.
Follow PRIMARY HYPERTENSION: new trials by email Literature Review of PRIMARY HYPERTENSION trials Research Report on PRIMARY HYPERTENSION
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Self-Acupressure on Blood Pressure, Stress, and Well-Being Levels in Individuals With Hypertension Real Acupressure, sham acupressure, Usual Care - PRIMARY HYPERTENSION | Not applicable | Not yet recruiting | Abant Izzet Baysal University | 72 | 2026-06-01 | 2026-05-14 |
| High-Intensity Transcranial Alternating Current Stimulation (Hi-tACS) for Hypertension: A Randomized Controlled Trial Active High-Intensity Transcranial Alternating Current Stimulation (Hi-tACS), Sham High-Intensity Transcranial Alternating Current Stimulation (Hi-tACS) - Primary Hypertension | Not applicable | Not yet recruiting | Xuanwu Hospital, Beijing | 50 | 2026-05-01 | 2026-05-05 |
| Dietary Nitrate and the Oral Microbiome in Children With Primary Hypertension No active intervention - Primary Hypertension | Recruiting | Yelda Kasımoğlu | 48 | 2026-04-15 | 2026-05-08 | |
| Endothelial Extracellular Vesicles as Biomarkers of Endothelial Activation in Children With Newly Diagnosed Hypertension Pediatric Hypertension, Primary Hypertension | Recruiting | Josip Juraj Strossmayer University of Osijek | 80 | 2026-04-01 | 2026-07-27 | |
| Bioequivalence Study of Sacubitril Alisartan Amlodipine Tablets Sequence A T-R-T-R, Sequence B R-T-R-T - Primary Hypertension | Phase 1 | Not yet recruiting | Shenzhen Salubris Pharmaceuticals Co., Ltd. | 60 | 2026-03-09 | 2026-03-20 |
| Automatic and Conventional Methods of Hypertensive Patients Monitoring blood pressure measurments devices - Primary Hypertension | Not yet recruiting | Assiut University | 620 | 2025-10-01 | 2025-04-16 | |
| A Study to Compare to PK Characteristics and Safety Profiles Between AD-227 and Co-administration of AD-227A and AD-227B Co-administration of AD-227A and AD-227B, Administration of AD-227 - Primary Hypertension | Phase 1 | Completed | Addpharma Inc. | 70 | 2025-07-12 | 2025-12-01 |
| The Effect of Lavender Inhalation on Anxiety, Sleep, and Blood Pressure Lavender - Primary Hypertension | Not applicable | Recruiting | Ardahan University | 50 | 2025-07-07 | 2025-09-25 |
| Text Message Support to Help Adults With Newly Diagnosed High Blood Pressure Control Their Blood Pressure in Primary Care Clinics in Germany and Pakistan mHealth Text Message Program, Usual Care - Hypertension, Primary Hypertension | Not applicable | Completed | GIFT University | 1295 | 2025-04-08 | 2026-10-16 |
| Assessment of Efficacy and Safety of Amicomed®, for the Management of Essential Hypertension Amicomed®, Digital Placebo, Usual Care - Essential Hypertension, Primary Hypertension | Not applicable | Unknown | Newel Health SRL | 316 | 2024-11-01 | 2023-10-23 |
| The Use of Virtual Reality and Music Therapy for Hypertensive Urgency Captopril 25Mg Tab, Virtual Reality Exposure, Classic Music Therapy - Hypertensive Urgency, Primary Hypertension | Not applicable | Completed | Ankara City Hospital Bilkent | 130 | 2024-08-01 | 2026-05-07 |
| Multi-Omics to Predict the Blood Pressure Response to Antihypertensives Amlodipine, Olmesartan, Hydrochlorothiazide - Primary Hypertension | Phase 4 | Unknown | Radboud University Medical Center | 96 | 2024-04-04 | 2024-06-10 |
| The Safety and Efficacy of Carotid Body Modulation Therapy in Hypertensive Patients by External Ultrasonic Micro-bubble External Ultrasonic Micro-bubble - Primary Hypertension | Not applicable | Not yet recruiting | Jing Huang | 200 | 2023-12-01 | 2023-11-03 |
| The Effectiveness of "MaRiTensi" in Increasing Self-Care and Blood Pressure Control: Randomized Controlled Trial MaRiTensi App - Primary Hypertension | Not applicable | Completed | Chatarina Setya Widyastuti | 99 | 2023-10-11 | 2024-07-09 |
| The Predictive Role of Urinary Proteomics in Blood Pressure Response of Obese Hypertensive Treated With Irbesartan or Eplerenone. Irbesartan 150mg, Eplerenone 25 mg - Primary Hypertension, Obesity | Not applicable | Unknown | Hippocration General Hospital | 50 | 2023-09-01 | 2024-01-17 |
| Treatment Optimisation for Blood Pressure With Single-Pill Combinations in India Amlodipine + Perindopril, Perindopril + Indapamide, Amlodipine + Indapamide - Primary Hypertension | Phase 4 | Completed | Centre for Chronic Disease Control, India | 1981 | 2022-08-30 | 2024-10-08 |
| A Randomized Patient Preference Trial on Heat-sensitive Moxibustion for Primary Hypertension in Community Heat-sensitive moxibustion plus original antihypertensive treatment (compulsively randomized arm), Original antihypertensive treatment (compulsively randomized arm), Heat-sensitive moxibustion plus antihypertensive treatment (voluntarily randomized arm) - Primary Hypertension | Not applicable | Completed | Jiangxi University of Traditional Chinese Medicine | 400 | 2021-03-10 | 2024-07-03 |
| Heat-sensitive Moxibustion Self-administration in Patients in the Community With Primary Hypertension: Protocol for a Multi-center, Pragmatic, Non-randomized Trial Heat-sensitive moxibustion plus antihypertensive drugs, Antihypertensive drugs - Primary Hypertension | Not applicable | Unknown | Jiangxi University of Traditional Chinese Medicine | 767 | 2020-05-20 | 2021-04-05 |
| Comparisonbetween Primary Hypertension Monitoring Methods for Detection of Early Kidney Dysfunction oscillometric device - Primary Hypertension | Unknown | Assiut University | 102 | 2019-08-01 | 2019-03-11 | |
| Pediatric Primary Hypertension and the Renin-Angiotensin System (PHRAS) Pediatric Disorder, Pediatric Obesity | Completed | Wake Forest University Health Sciences | 35 | 2018-12-03 | 2025-02-28 |
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Essential Hypertension (39) · Hypertension (13) · Hypertrophy, Left Ventricular (2) · Obesity (2) · Anxiety Disorders (1) · Aortic Valve Stenosis (1) · Emergencies (1) · Familial Primary Pulmonary Hypertension (1) · Hypertension Resistant to Conventional Therapy (1) · Hypertensive Crisis (1) · Medication Adherence (1) · Patient Compliance (1) · Pediatric Obesity (1) · Renal Insufficiency (1) · Sleep Initiation and Maintenance Disorders (1)
Cardiovascular Diseases (39) · Vascular Diseases (39) · Hypertension (26) · Pathological Conditions, Signs and Symptoms (4) · Heart Diseases (3) · Body Weight (2) · Cardiomegaly (2) · Hypertrophy (2) · Nervous System Diseases (2) · Nutrition Disorders (2) · Nutritional and Metabolic Diseases (2) · Overnutrition (2) · Overweight (2) · Pathological Conditions, Anatomical (2) · Signs and Symptoms (2)
Amlodipine (3) · Hydrochlorothiazide (3) · Angiotensin-Converting Enzyme Inhibitors (2) · Antihypertensive Agents (2) · Spironolactone (2) · Albuterol (1) · Amlodipine Besylate, Olmesartan Medoxomil Drug Combination (1) · Amlodipine, Valsartan Drug Combination (1) · Arginine (1) · Bisoprolol (1) · Captopril (1) · Enalapril (1) · Eplerenone (1) · Exercise (1) · Folic Acid (1)
Assiut University (2) · AstraZeneca (2) · Bayer (2) · Jiangxi University of Traditional Chinese Medicine (2) · Radboud University Medical Center (2) · Abant Izzet Baysal University (1) · Addpharma Inc. (1) · Ankara City Hospital Bilkent (1) · Ardahan University (1) · Centre for Chronic Disease Control, India (1) · Chatarina Setya Widyastuti (1) · China Academy of Chinese Medical Sciences (1) · Chinese Academy of Medical Sciences, Fuwai Hospital (1) · Comenius University (1) · Eli Lilly and Company (1)
China (12) · Turkey (Türkiye) (4) · India (2) · Netherlands (2) · United States (2) · Belgium (1) · Canada (1) · Croatia (1) · Egypt (1) · Finland (1) · Germany (1) · Greece (1) · Indonesia (1) · Pakistan (1) · Poland (1)
Ahmed Abdel Galeel, MD (1) · Andrew M South, MD MS (1) · Carel Bakx, MD PhD (1) · Chatarina S Widyastuti (1) · Chi-Wen Kao, Ph.D. (1) · Doaa Fouad (1) · Domenico Cianflone, MD, PhD (1) · Donald M. Morisky, Sc.D., M.S.P.H., Sc.M. (1) · Dorairaj Prabhakaran, DM Cardiology (1) · Gabriela Teodorescu (1) · Haipeng Xiao, PhD (1)
PMID 21403139, PMID 22850357, PMID 24237764, PMID 25153328, PMID 25771069, PMID 26474738, PMID 26991917, PMID 27216309, PMID 27266507, PMID 27294333, PMID 27329447, PMID 27548766, PMID 27729579, PMID 28122783, PMID 28148501, PMID 28288974, PMID 28360116, PMID 28607125, PMID 28968870, PMID 29018022, PMID 29030456, PMID 29273594, PMID 29371246, PMID 29747834, PMID 30354996, PMID 30372582, PMID 30624586, PMID 30713028, PMID 30925145, PMID 31161196, PMID 31414959, PMID 31446884, PMID 31462258, PMID 31626649, PMID 31718666, PMID 31804186, PMID 31806397, PMID 31838255, PMID 31846980, PMID 32371787, PMID 32723980, PMID 32905623, PMID 32915349, PMID 32957364, PMID 33099298, PMID 33188272, PMID 33769555, PMID 33793326, PMID 34003685, PMID 34039285
2009 (1), 2023 (1)