21 completed, 18 unknown, 4 recruiting, 4 terminated. 14 Phase 4, 10 Phase 1, 10 Phase 2, 10 Phase 3, 6 Not applicable.
Follow Captopril: new trials by email Literature Review of Captopril trials Research Report on Captopril
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD) Finerenone, Semaglutide, Lotensin - Chronic Kidney Disease, Type 2 Diabetes | Phase 4 | Enrolling by invitation | Baylor Research Institute | 64 | 2026-04-08 | 2026-10-13 |
| The Use of Virtual Reality and Music Therapy for Hypertensive Urgency Captopril 25Mg Tab, Virtual Reality Exposure, Classic Music Therapy - Hypertensive Urgency, Primary Hypertension | Not applicable | Completed | Ankara City Hospital Bilkent | 130 | 2024-08-01 | 2026-05-07 |
| Captopril Use on the Degree of Marrow Fibrosis in Bone Marrow Fibrosis/Myeloproliferative Neoplasms Captopril - Bone Marrow Fibrosis, Myeloproliferative Neoplasm | Phase 1 / Phase 2 | Withdrawn | Case Comprehensive Cancer Center | 2024-04-01 | 2023-10-11 | |
| NW Roselle in Grade 1 Essential Hypertension: Phase III Clinical Trial NW Roselle, Captopril 25Mg Tab - Essential Hypertension | Phase 3 | Unknown | Natural Wellness Egypt | 286 | 2024-03-01 | 2023-11-21 |
| A Study to Investigate the Effect of Urine Acid-base Disequilibrium on the Pharmacokinetics of Captopril Captopril 12.5 Mg, Sodium bicarbonate 4 G, Torsemide 20 MG - Hypertension | Phase 1 | Completed | Seoul National University Hospital | 12 | 2024-02-28 | 2025-05-30 |
| Effect of Captopril on GLS in Duchenne Myodystrophy Captopril Tablets - Effect of Drug | Early Phase 1 | Unknown | Ain Shams University | 20 | 2024-01-01 | 2024-07-16 |
| Cardioprotection on Chemotherapy-Induced Cardiotoxicity ACE Inhibitors, β -Blockers - Cardiotoxicity | Phase 3 | Recruiting | Ain Shams University | 30 | 2023-07-18 | 2025-03-03 |
| Effect of Sodium-glucose Cotransporter-2 Inhibitors (SGLT-2i) on Proteinuria in Nephrotic Children Older Than 10 Years ACEI, SGLT-2i - Nephrotic Syndrome in Children | Phase 4 | Unknown | Mansoura University | 60 | 2023-06-01 | 2024-05-16 |
| Alpha-lipoic Acid in Diabetic Nephropathy Thioctic Acid 333 MG Oral Capsule, Captopril 25Mg Tab - Type 1 Diabetes | Phase 3 | Unknown | Ain Shams University | 30 | 2023-01-01 | 2024-02-12 |
| Study of Innovative Drug Treatment Therapy for Pediatric Mitral Regurgitation Captopril Tablets, Metoprolol Oral Tablet, Spironolactone Tablets - Congenital Mitral Insufficiency | Unknown | China National Center for Cardiovascular Diseases | 122 | 2022-04-01 | 2023-09-15 | |
| Study of Innovative Drug Strategies in Improving Left Ventricular Function After Mitral Repair Captopril Tablets, Metoprolol Oral Tablet, Spironolactone Tablets - Congenital Mitral Insufficiency | Unknown | China National Center for Cardiovascular Diseases | 164 | 2022-04-01 | 2023-09-15 | |
| Bioequivalence Study Between Capoten Versus Captopril Reference Product in Healthy Adult Participants Under Fasting Conditions Capoten, Captopril - Healthy Volunteers | Phase 1 | Withdrawn | GlaxoSmithKline | 2022-02-13 | 2023-01-27 | |
| Study of Drug Therapy for Pediatric Heart Failure Captopril Tablets, Metoprolol Oral Tablet, Spironolactone Tablets - Heart Failure Congenital | Unknown | China National Center for Cardiovascular Diseases | 200 | 2022-01-01 | 2023-09-15 | |
| New Horizons for the Treatment of Cardiomyopathy in Children mono nuclear cells injection, Digoxin+furosemide+captopril - Cardiomyopathy | Not applicable | Terminated | Damascus University | 22 | 2021-05-20 | 2025-02-20 |
| Hormone Therapy and Angiotensin-Dependent Arterial and Renal Vasoconstriction in Humans Captopril Tablets, Iohexol - Hormone Therapy | Recruiting | University of Calgary | 200 | 2020-11-30 | 2025-03-27 | |
| Efficacy of Captopril in Covid-19 Patients With Severe Acute Respiratory Syndrome (SARS) CoV-2 Pneumonia (CAPTOCOVID) captopril 25mg - Pneumonia, Coronavirus Infection | Phase 2 | Unknown | Assistance Publique - Hôpitaux de Paris | 230 | 2020-05-05 | 2020-04-28 |
| Coronavirus (COVID-19) ACEi/ARB Investigation Thiazide or Thiazide-like diuretics, Calcium Channel Blockers, ACE inhibitor - Hypertension, COVID-19 | Phase 4 | Suspended | National University of Ireland, Galway, Ireland | 2414 | 2020-04-30 | 2020-06-30 |
| Angiotensin Converting Enzyme Inhibitors in Treatment of Covid 19 ACEIs, Conventional treatment - COVID | Phase 3 | Not yet recruiting | Tanta University | 60 | 2020-04-15 | 2020-04-14 |
| Captopril Versus Atenolol to Prevent Expansion Rate of Thoracic Aortic Aneurysms Atenolol - Aneurysm | Not applicable | Unknown | Onassis Cardiac Surgery Centre | 424 | 2020-03-07 | 2020-01-13 |
| ACEI or ARB and COVID-19 Severity and Mortality in US Veterans ACEI/ARB, Non-ACEI/ARB, ACEI - Hypertension, COVID | Completed | University of Utah | 22213 | 2020-01-19 | 2021-04-28 |
Showing 20 of 52. Sign in to see all of them.
Hypertension (10) · Diabetes Mellitus, Type 2 (5) · COVID-19 (3) · Essential Hypertension (3) · Heart Failure (3) · Kidney Diseases (3) · Cardiomyopathies (2) · Cardiotoxicity (2) · Cardiovascular Diseases (2) · Coronavirus Infections (2) · Diabetes Mellitus (2) · Diabetes Mellitus, Type 1 (2) · Heart Defects, Congenital (2) · Heart Diseases (2) · Mitral Valve Insufficiency (2)
Ain Shams University (4) · China National Center for Cardiovascular Diseases (3) · Northwestern University (2) · Tanta University (2) · Vanderbilt University (2) · Alfa Wassermann Tunisia (1) · Ankara City Hospital Bilkent (1) · Assistance Publique - Hôpitaux de Paris (1) · AstraZeneca (1) · Baylor Research Institute (1) · Brigham and Women's Hospital (1) · Cairo University (1) · Case Comprehensive Cancer Center (1) · Centro Neurológico de Pesquisa e Reabiitação, Brazil (1) · Children's Cancer Hospital Egypt 57357 (1)
United States (13) · Egypt (9) · China (6) · Canada (3) · France (3) · United Kingdom (3) · Brazil (2) · Germany (2) · Ireland (2) · Netherlands (2) · New Zealand (2) · Spain (2) · Australia (1) · Austria (1) · Belgium (1)
Shoujun Li, MD (3) · Italo Biaggioni, MD (2) · Aaron Gerds, MD (1) · Adam P Bress, PharmD, MS (1) · Ahmed El Refaey, MBBCh,MSc,MD (1) · Alfonso M. M Cueto-Manzano, MD, MSc, PhD (1) · Amin Banihashemi (1) · Bjorn Eriksson, MD (1) · Carlos Noronha, MD (1) · Cesar Minelli, MD, PhD (1) · Christian Hassager, MD, Phd (1) · Colin McArthur, Dr (1) · Dalia Zaafar, PhD (1) · Derek Angus, Prof (1)
PMID 10851208, PMID 11927799, PMID 12119802, PMID 12923400, PMID 15738343, PMID 16001071, PMID 16166518, PMID 16391172, PMID 16533484, PMID 18426998, PMID 19047577, PMID 19738158, PMID 20139439, PMID 21051458, PMID 22002336, PMID 22157565, PMID 22394464, PMID 22801444, PMID 22892920, PMID 23266540, PMID 23899372, PMID 25926990, PMID 26039598, PMID 26811272, PMID 27207965, PMID 27294333, PMID 27298661, PMID 27819381, PMID 27819386, PMID 28125624, PMID 30261084, PMID 32109013, PMID 32125455, PMID 32267771, PMID 32371787, PMID 32842783, PMID 32876697, PMID 33394942, PMID 33509275, PMID 33536102, PMID 33631065, PMID 33891615, PMID 34251506, PMID 34351721, PMID 34351722, PMID 34473343, PMID 34606578, PMID 34620071, PMID 34825613, PMID 34959641
2015 (1), 2023 (1), R01HL093238 (1)