11 completed, 5 recruiting, 1 not yet recruiting. 6 Phase 4, 5 Not applicable, 3 Phase 2, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 6 | Completed 6 |
| Not applicable | 5 | Recruiting 3, Completed 1, Not yet recruiting 1 |
| Phase 2 | 3 | Completed 2, Recruiting 1 |
| Phase 3 | 3 | Completed 2, Recruiting 1 |
Follow Premedication: new trials by email Literature Review of Premedication trials Research Report on Premedication
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparative Assessment of Oral Premedication Regimens in Pediatric Ambulatory Surgery Oral Midazolam Premedication, Oral Midazolam plus Ibuprofen Premedication, Oral Midazolam plus Ketamine Premedication - Pediatric Anesthesia, Premedication | Not applicable | Recruiting | Diskapi Yildirim Beyazit Education and Research Hospital | 135 | 2026-07-26 | 2026-07-28 |
| 1-hour Premedication for Allergy Goal in Emergency: PAGE-1 Study IV glucocorticoid and antihistamine, IV glucocorticoid and antihistamine (standard of care) - Allergic Reaction to Contrast Media, Hypersensitivity Reaction | Not applicable | Not yet recruiting | Paul Peng, MD PhD MSCR | 540 | 2026-06-01 | 2026-02-19 |
| Effect of Virtual Reality on the Need of Premedication Before Surgery Virtual Reality - Anxiety, Premedication | Not applicable | Recruiting | Ente Ospedaliero Cantonale, Bellinzona | 40 | 2025-11-11 | 2026-03-04 |
| Premedication With N-acetylcysteine and Simethicone to Improve Mucosal Visualization in Elective Upper Endoscopy Premedication with n-acetylcysteine, Placebo (drinking water), Premedication with simethicone - Esophagogastroduodenoscopy, Simethicone | Phase 2 | Recruiting | Hospital General de Mexicali | 132 | 2025-09-12 | 2025-11-24 |
| Anxiolytic Effect of Virtual Reality Immersion Versus Midazolam Premedication in Patients Undergoing Dacryocystorhinostomy Surgery Virtual Reality Group, Midazolam Group - Anxiolytic Effect, Virtual Reality Immersion | Not applicable | Recruiting | Cairo University | 40 | 2025-06-01 | 2025-07-03 |
| Premedication on Post-endodontic Pain Root canal treatment - Premedication | Phase 3 | Recruiting | Gulf Medical University | 48 | 2024-09-01 | 2024-11-04 |
| Nebulized Lidocaine And Ketamine Before Fiberoptic Bronchoscopy Nebulized lidocaine and ketamine, Nebulized Lidocaine, Lidocaine spray (2%) - Fiberoptic Bronchoscopy (FOB), Lung Cancer (Diagnosis) | Phase 4 | Completed | Alexandria University | 134 | 2024-09-01 | 2026-08-03 |
| Intranasal Versus Intravenous Dexmedetomidine for Hypotensive Anesthesia in FESS Intranasal dexmedetomidine, Intravenous dexmedetomidine - Functional Endoscopic Sinus Surgery, Premedication | Phase 4 | Completed | Al-Azhar University | 60 | 2022-11-10 | 2023-03-14 |
| EMERGENCE AGITATION After Premedication IN PAEDIATRIC MAGNETIC RESONANCE IMAGING: A RETROSPECTIVE COHORT STUDY Autism Spectrum Disorder, Premedication | Completed | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 100 | 2022-03-01 | 2023-07-17 | |
| Preoperative Anxiety Level, Premedications and General Anaesthetic Proceedings Anxiety, Premedication | Completed | CHU de Reims | 1200 | 2017-03-03 | 2018-07-27 | |
| Dexmedetomidine Premedication in Children Dexmedetomidine, apple juice - Premedication | Phase 4 | Completed | Aydin Adnan Menderes University | 100 | 2017-03-01 | 2017-06-02 |
| Oral Dexmedetomidine vs Midazoam For Premedication Precedex, Midazolam - Premedication | Phase 4 | Completed | Aydin Adnan Menderes University | 52 | 2016-11-01 | 2020-05-29 |
| Assessing the Effectiveness of Midazolam Premedication Midazolam premedication, Remifentanil infusion, Propofol infusion - Midazolam Premedication, Anxiety Preoperative | Not applicable | Completed | Pusan National University Hospital | 128 | 2016-07-19 | 2017-10-31 |
| Cerebral NIRS Profiles During Premedication for Neonatal Intubation atropine+ propofol, atropine + atracurium + sufentanil - Premedication, Endotracheal Intubation | Phase 2 / Phase 3 | Completed | Centre Hospitalier Intercommunal Creteil | 28 | 2016-03-01 | 2019-08-09 |
| Intranasal Dexmedetomidine vs Midazolam-ketamine Combination for Premedication of Pediatric Patients Dexmedetomidine, Ketamine - Premedication, Oculocardiac Reflex | Phase 4 | Completed | TC Erciyes University | 60 | 2014-02-01 | 2015-04-14 |
| Melatonin Premedication in Children Undergoing Surgery melatonin in children premedication, midazolam in children premedication - Premedication, Anaesthesia | Phase 4 | Completed | Azienda Ospedaliera Universitaria Policlinico "G. Martino" | 92 | 2012-09-01 | 2014-10-16 |
| Premedication Trial for Tracheal Intubation of the NEOnate atropine+ propofol, atropine + atracurium + sufentanil - Premedication, Endotracheal Intubation | Phase 2 / Phase 3 | Completed | Centre Hospitalier Intercommunal Creteil | 173 | 2012-05-01 | 2021-03-04 |
Anxiety Disorders (3) · Agnosia (1) · Autism Spectrum Disorder (1) · Brain Neoplasms (1) · Disease (1) · Emergence Delirium (1) · Hypersensitivity (1) · Lung Neoplasms (1) · Pain (1) · Stomach Neoplasms (1)
Mental Disorders (5) · Pathological Conditions, Signs and Symptoms (4) · Neoplasms (3) · Neoplasms by Site (3) · Nervous System Diseases (3) · Neurologic Manifestations (3) · Signs and Symptoms (3) · Neurobehavioral Manifestations (2) · Pathologic Processes (2) · Brain Diseases (1) · Central Nervous System Diseases (1) · Central Nervous System Neoplasms (1) · Child Development Disorders, Pervasive (1) · Confusion (1) · Delirium (1)
Midazolam (4) · Dexmedetomidine (3) · Atracurium (2) · Atropine (2) · Ketamine (2) · Propofol (2) · Sufentanil (2) · Acetylcysteine (1) · Drinking Water (1) · Fentanyl (1) · Glucocorticoids (1) · Histamine Antagonists (1) · Isoflurane (1) · Melatonin (1) · Oxygen (1)
Aydin Adnan Menderes University (2) · Centre Hospitalier Intercommunal Creteil (2) · Al-Azhar University (1) · Alexandria University (1) · Azienda Ospedaliera Universitaria Policlinico "G. Martino" (1) · CHU de Reims (1) · Cairo University (1) · Diskapi Yildirim Beyazit Education and Research Hospital (1) · Ente Ospedaliero Cantonale, Bellinzona (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Gulf Medical University (1) · Hospital General de Mexicali (1) · Paul Peng, MD PhD MSCR (1) · Pusan National University Hospital (1) · TC Erciyes University (1)
Egypt (3) · France (3) · Turkey (Türkiye) (3) · Italy (1) · Mexico (1) · South Korea (1) · Switzerland (1) · United Arab Emirates (1)
Carmelo Romeo, Prof (1) · Hyeon-Jeong Lee, PhD (1) · Meryl Vedrenne-Cloquet, MD (1) · Paul Peng (1) · Rossella Garra (1) · Xavier Durrmeyer, MD (1) · Xavier Durrmeyer, MD, PhD (1)
PMID 15318468, PMID 17122221, PMID 17198534, PMID 23825812, PMID 24325147, PMID 27614989, PMID 28904966, PMID 29715354, PMID 29971260, PMID 30881948, PMID 31044749, PMID 31299247, PMID 32016519, PMID 33301785