6 completed, 3 unknown, 1 not yet recruiting, 1 recruiting. 12 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 12 | Completed 6, Unknown 3, Not yet recruiting 1, Recruiting 1, Terminated 1 |
| Phase 2 | 1 | Recruiting 1 |
Follow Postoperative Ileus: new trials by email Literature Review of Postoperative Ileus trials Research Report on Postoperative Ileus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neuromuscular Blocking Agents on Gastrointestinal Function Following Colorectal Surgery Neostigmine + Atropine, Sugammadex - Postoperative Gastrointestinal Dysfunction (POGD), Postoperative Ileus | Phase 3 | Not yet recruiting | Xijing Hospital | 560 | 2026-01-01 | 2025-12-09 |
| Pyridostigmine Efficacy and Safety for Treatment of Ileus After Colorectal Surgery Pyridostigmine Bromide, Placebo - Postoperative Ileus | Phase 2 / Phase 3 | Recruiting | Stefan Holubar MD MS FACS, FASCRS | 50 | 2024-09-03 | 2026-01-07 |
| Effect of Multimodal Opioid-free Anesthesia on Return of Bowel Function in Laparoscopic Colorectal Surgery Acetaminophen, Gabapentin, Lidocaine 1% Injectable Solution, Dexmedetomidine, Ketamine, Dexamethasone, Ondansetron - Anesthesia, General Anesthesia | Phase 3 | Unknown | University of Saskatchewan | 60 | 2021-05-15 | 2023-12-20 |
| Prucalopride in Postoperative Ileus Prucalopride, Placebo Oral Capsule - Postoperative Ileus, Colorectal Surgery | Phase 3 | Completed | University of Auckland, New Zealand | 150 | 2017-10-25 | 2021-09-29 |
| Anti-inflammatory Effect of Peroperative Stimulation of the Vagus Nerve Sham stimulation, Vagus stimulation - Postoperative Ileus | Phase 3 | Completed | KU Leuven | 130 | 2017-07-01 | 2023-02-10 |
| Electroacupuncture Versus Fast-track Perioperative Program for Laparoscopic Colorectal Surgery Electroacupuncture, Fast-track program - Postoperative Ileus | Phase 3 | Unknown | Chinese University of Hong Kong | 164 | 2014-01-01 | 2014-02-11 |
| Study of Dexamethasone-Allantoin-Metronidazole (DAM) Solution in the Treatment of Post-Operative Ileus (POI) DAM, Normal Saline - Postoperative Ileus | Phase 3 | Unknown | Beijing Bozhiyin T&S Co., Ltd. | 480 | 2013-04-01 | 2013-05-29 |
| Study to Evaluate the Safety of Post-Operative TZP-101 (IV Ulimorelin) After Partial Bowel Resection TZP-101, Placebo - Postoperative Ileus | Phase 3 | Completed | Norgine | 27 | 2012-02-01 | 2024-09-19 |
| Effects of Chewing Gum Against Postoperative Ileus Chewing gum, Glucose - Postoperative Ileus | Phase 3 | Terminated | Thomas Andersson | 65 | 2012-01-01 | 2014-12-18 |
| Does Coffee Consumption Prevent or Shorten Postoperative Ileus After Colon Resection? caffeinated coffee - Postoperative Ileus | Phase 3 | Completed | University of Massachusetts, Worcester | 44 | 2010-04-01 | 2013-06-11 |
| Electroacupuncture for Postoperative Ileus After Laparoscopic Colorectal Surgery Electroacupuncture, Sham Acupuncture, No Acupuncture - Postoperative Ileus | Phase 3 | Completed | Chinese University of Hong Kong | 165 | 2008-10-01 | 2011-04-21 |
| Effects of Intravenous Local Anesthetic on Bowel Function After Colectomy bupivacaine with hydromorphone, lidocaine - Postoperative Ileus | Phase 3 | Completed | University of Virginia | 45 | 2005-04-01 | 2008-01-24 |
Agnosia (1) · Digestive System Diseases (1) · Gastrointestinal Diseases (1) · Ileus (1) · Intestinal Diseases (1) · Intestinal Obstruction (1) · Postoperative Complications (1)
Pathological Conditions, Signs and Symptoms (2) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1) · Neurologic Manifestations (1) · Pathologic Processes (1) · Perceptual Disorders (1) · Signs and Symptoms (1)
Electroacupuncture (2) · Lidocaine (2) · Acetaminophen (1) · Atropine (1) · Bupivacaine (1) · Chewing Gum (1) · Dexamethasone (1) · Dexmedetomidine (1) · Gabapentin (1) · Glucose (1) · Hydromorphone (1) · Injections (1) · Ketamine (1) · Magnesium Sulfate (1) · Neostigmine (1)
Chinese University of Hong Kong (2) · Beijing Bozhiyin T&S Co., Ltd. (1) · KU Leuven (1) · Norgine (1) · Stefan Holubar MD MS FACS, FASCRS (1) · Thomas Andersson (1) · University of Auckland, New Zealand (1) · University of Massachusetts, Worcester (1) · University of Saskatchewan (1) · University of Virginia (1) · Xijing Hospital (1)
China (3) · United States (3) · Belgium (1) · Canada (1) · New Zealand (1)
Guy Boeckxstaens, M.D. (1) · Kristin Falk, PhD (1) · Marcel E Durieux, MD PhD (1) · Sandy Eisen, MD (1) · Simon S. M. Ng, MD (1) · Simon SM Ng, FRCSEd (Gen) (1) · Stefan D Holubar (1) · Thomas Andersson, MSc (1) · Ying-jiang Ye, professor (1)