178 terminated. 178 Phase 3, 54 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 178 | Terminated 178 |
| Phase 2 | 54 | Terminated 54 |
Follow Pneumonia: new trials by email Literature Review of Pneumonia trials Research Report on Pneumonia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Metoprolol in Acute Respiratory Distress Syndrome (MAIDEN) Metoprolol Injection, saline 0.9% - Acute Respiratory Distress Syndrome (ARDS) | Phase 3 | Terminated | Consorcio Centro de Investigación Biomédica en Red (CIBER) | 14 | 2024-07-10 | 2026-06-02 |
| Evaluating Emetine for Viral Outbreaks (EVOLVE) Emetine Hydrochloride, Placebo - COVID-19 | Phase 2 / Phase 3 | Terminated | Johns Hopkins University | 4 | 2024-05-15 | 2026-01-23 |
| Treatment of Long CoronaVirus Disease (COVID) (TLC) Feasibility Trial Cetirizine, Famotidine, Cetirizine Placebo - COVID-19 | Phase 3 | Terminated | Emory University | 5 | 2024-03-08 | 2025-07-17 |
| Study of Obeldesivir in Children and Adolescents With COVID-19 Obeldesivir - COVID-19 | Phase 2 / Phase 3 | Terminated | Gilead Sciences | 3 | 2023-12-26 | 2025-02-03 |
| Efficacy and Safety of COVID-19 Vaccine as Booster Vaccination in Adults 18 Years of Age or Older Recombinant SARS-CoV-2 Vaccine (CHO Cell) LYB001, Placebo - COVID-19 | Phase 3 | Terminated | Guangzhou Patronus Biotech Co., Ltd. | 3000 | 2022-12-29 | 2023-09-28 |
| Strategies and Treatments for Respiratory Infections & Viral Emergencies (STRIVE): Shionogi Protease Inhibitor (Ensitrelvir) Shionogi Protease Inhibitor (S-217622), placebo - COVID-19 | Phase 3 | Terminated | University of Minnesota | 602 | 2022-12-23 | 2026-09-24 |
| Efficacy and Safety of Trimodulin (BT588) in Subjects With CAP Including COVID-19 Pneumonia Trimodulin, Placebo (human albumin 1%) - Respiratory Infection, Pneumonia | Phase 3 | Terminated | Biotest | 107 | 2022-12-22 | 2025-06-08 |
| Evaluating the Safety and Efficacy of AD17002 Intranasal Spray in Treating Participants With Mild to Moderate COVID-19 AD17002 + Formulation buffer, Placebo - COVID-19 | Phase 2 / Phase 3 | Terminated | Advagene Biopharma Co. Ltd. | 180 | 2022-12-01 | 2025-09-10 |
| Study of Obeldesivir in Participants With COVID-19 Who Have a High Risk of Developing Serious or Severe Illness Obeldesivir, Obeldesivir Placebo - COVID-19 | Phase 3 | Terminated | Gilead Sciences | 468 | 2022-11-05 | 2024-12-20 |
| Asunercept for the Treatment of Patients With Moderate to Severe COVID-19 Disease Asunercept, Placebo - COVID-19 | Phase 3 | Terminated | Apogenix GmbH | 34 | 2022-11-03 | 2023-08-29 |
| International Sites: Novel Experimental COVID-19 Therapies Affecting Host Response Fostamatinib, Placebo - COVID-19, SARS-CoV2 Infection | Phase 2 / Phase 3 | Terminated | NEAT ID Foundation | 28 | 2022-10-27 | 2025-05-02 |
| A Human Monoclonal Antibody Against Staphylococcus Aureus Alpha Toxin in Mechanically Ventilated Adult Subjects - 2 Suvratoxumab, Placebo - Ventilator Associated Pneumonia, Staphylococcus Aureus | Phase 3 | Terminated | Aridis Pharmaceuticals, Inc. | 24 | 2022-09-02 | 2025-03-24 |
| Real World Evaluation of the Effectiveness of AZD7442 for Prevention of SARS-CoV-2 Evusheld (tixagevimab+cilgavimab) IM or IV - SARS-CoV-2 Infection | Phase 3 | Terminated | MediMergent, LLC | 550 | 2022-06-03 | 2023-09-08 |
| Evaluation of Full Versus Fractional Doses of COVID-19 Vaccines Given as a Booster in Adults in Australia - Mongolia, Indonesia, Australia Coronavirus (MIACoV). Tozinameran - Standard dose, Tozinameran - fractional dose, Elasomeran - standard dose - COVID-19 | Phase 3 | Terminated | Murdoch Childrens Research Institute | 13 | 2022-05-02 | 2024-12-16 |
| Reparixin add-on Therapy to Standard Care to Limit Progression in Pts With COVID19 & Other Community Acquired Pneumonia Reparixin, Placebo - Infectious Pneumonia, Severe COVID-19 | Phase 3 | Terminated | Dompé Farmaceutici S.p.A | 414 | 2022-04-27 | 2026-02-24 |
| Janssen Ad26.CoV2.S Vaccine Booster in Kidney Transplant Recipients Janssen Ad26.CoV2.S Vaccine, Reduction in Immunosuppression Medication, Maintenance in Immunosuppression Medication - Kidney Transplant Recipient | Phase 3 | Terminated | Mark Stegall | 468 | 2022-04-11 | 2025-09-15 |
| Early High-Titre Convalescent Plasma in Clinically Vulnerable Individuals With Mild COVID-19 Current standard of care and COVID-19 convalescent and vaccinated plasma, Current standard of care - COVID-19 | Phase 3 | Terminated | Deutsches Rotes Kreuz DRK-Blutspendedienst Baden-Wurttemberg-Hessen | 120 | 2022-04-01 | 2024-10-29 |
| A Study to Evaluate the Safety and Immunogenicity of Ad5-nCoV and Ad5-nCoV-IH in CoronaVac Immunized Children and Adolescents Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector), Recombinant COVID-19 vaccine (adenovirus type 5 vector) for Inhalation (Ad5-nCoV-IH) - COVID-19 | Phase 3 | Terminated | CanSino Biologics Inc. | 91 | 2022-02-25 | 2023-06-15 |
| Ivermectin for Post Exposure Prophylaxis of Covid-19 Ivermectin, Placebo - COVID-19 | Phase 3 | Terminated | Clinical Research Centre, Malaysia | 50 | 2022-02-16 | 2022-10-18 |
| An Open-Label Study of Apabetalone in Covid Infection Apabetalone, Standard of care - COVID-19 Infection | Phase 2 / Phase 3 | Terminated | Resverlogix Corp | 1 | 2022-01-14 | 2023-11-18 |
Showing 20 of 178. Sign in to see all of them.
COVID-19 (143) · Coronavirus Infections (24) · Respiratory Distress Syndrome (17) · Severe Acute Respiratory Syndrome (12) · Pneumonia, Ventilator-Associated (11) · Pneumonia, Viral (8) · Respiratory Insufficiency (6) · Community-Acquired Pneumonia (4) · Acute Lung Injury (3) · Cytokine Release Syndrome (3) · HIV Infections (3) · Hypertension, Pulmonary (3) · Inflammation (3) · Pneumonia, Aspiration (3)
Infections (177) · Respiratory Tract Diseases (176) · Respiratory Tract Infections (175) · Lung Diseases (174) · Virus Diseases (149) · RNA Virus Infections (148) · Coronaviridae Infections (144) · Nidovirales Infections (144) · Pneumonia, Viral (139) · Coronavirus Infections (121) · Pathological Conditions, Signs and Symptoms (31) · Pathologic Processes (26) · Respiration Disorders (22) · Disease Attributes (15)
Hydroxychloroquine (17) · Sodium Chloride (10) · Standard of Care (9) · Azithromycin (7) · Saline Solution (7) · remdesivir (6) · Dexamethasone (4) · BNT162 Vaccine (3) · Trimethoprim, Sulfamethoxazole Drug Combination (3) · casirivimab and imdevimab drug combination (3) · ADG20 (2) · Amoxicillin (2) · Amoxicillin-Potassium Clavulanate Combination (2) · Cholecalciferol (2) · Colchicine (2)
Assistance Publique - Hôpitaux de Paris (4) · Gilead Sciences (4) · NICHD Neonatal Research Network (3) · National Institute of Allergy and Infectious Diseases (NIAID) (3) · Centre Hospitalier Universitaire de Saint Etienne (2) · Daewoong Pharmaceutical Co. LTD. (2) · Dompé Farmaceutici S.p.A (2) · Erasmus Medical Center (2) · Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina (2) · Invivyd, Inc. (2) · Janssen Research & Development, LLC (2) · McGill University Health Centre/Research Institute of the McGill University Health Centre (2) · Milton S. Hershey Medical Center (2) · Pfizer (2) · Polyphor Ltd. (2)
United States (83) · France (34) · Spain (34) · Brazil (27) · Mexico (23) · Canada (19) · South Africa (19) · Germany (16) · Argentina (15) · Ukraine (15) · Belgium (12) · Italy (12) · Poland (10) · United Kingdom (10) · Australia (9)
Bart Rijnders, MD, PhD (3) · Edward F. Donovan, MD (3) · Richard A. Ehrenkranz, MD (3) · Seetha Shankaran, MD (3) · Abbot R. Laptook, MD (2) · Avroy A. Fanaroff, MD (2) · Cavan Reilly, PhD (2) · G. Ganesh Konduri, MD (2) · James A. Lemons, MD (2) · Krisa P. Van Meurs, MD (2) · Lu-Ann Papile, MD (2) · Mary Wearden, MD (2) · Neil N. Finer, MD (2)
PMID 34473343, PMID 37591523, PMID 36695483, PMID 31986264, PMID 35713300, PMID 10802492, PMID 11416871, PMID 12904626, PMID 14510322, PMID 14993550, PMID 15198728, PMID 15616839, PMID 16000352, PMID 17307536, PMID 17443204, PMID 17517240, PMID 17586184, PMID 17914053, PMID 18230259, PMID 18337740, PMID 18378947, PMID 19067285, PMID 20607114, PMID 21248066, PMID 21732834, PMID 22120766, PMID 23148736, PMID 24105456, PMID 24108510, PMID 25030060, PMID 25050644, PMID 25855884, PMID 25904375, PMID 25991468, PMID 26472037, PMID 26735992, PMID 26872154, PMID 27080532, PMID 28891835, PMID 29041861, PMID 29149418, PMID 29422724, PMID 31995857, PMID 31996494, PMID 32003551, PMID 32007143, PMID 32015507, PMID 32015508, PMID 32027631, PMID 32031570
M01RR000070 (3), M01RR000750 (3), M01RR006022 (3), M01RR008084 (3), U10HD021373 (3), U10HD021385 (3), U10HD021397 (3), U10HD027853 (3), U10HD027856 (3), U10HD027871 (3), U10HD027880 (3), U10HD027904 (3), U10HD034216 (3), M01RR000633 (2), M01RR000997 (2)