8 unknown, 5 completed, 3 recruiting, 1 enrolling by invitation. 9 Not applicable, 3 Phase 2, 2 Phase 1, 2 Phase 4, 1 Early Phase 1.
Follow Photodynamic Therapy: new trials by email Literature Review of Photodynamic Therapy trials Research Report on Photodynamic Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Topical Imipramine on Photodynamic Therapy-Mediated Immunosuppression on Forearms or Face on US Veterans Imipramine, Control Vehicle - Actinic Keratosis, Imipramine | Phase 2 | Recruiting | VA Office of Research and Development | 48 | 2025-04-01 | 2025-12-22 |
| Hematoporphyrin Photodynamic Therapy for Esophageal Cancer photodynamic therapy - Esophageal Cancer, Photodynamic Therapy | Phase 4 | Enrolling by invitation | Sun Yat-sen University | 198 | 2024-09-18 | 2026-05-22 |
| Combination of Micropulse Laser With or Without Photodynamic Therapy for Chronic Central Serous Chorioretinopathy Central Serous Chorioretinopathy, Micropulse Laser | Unknown | Beijing Hospital | 60 | 2024-06-15 | 2024-06-21 | |
| Study to Evaluate the Efficacy, Safety and Tolerability of Photodynamic Therapy(PDT) With Chlorin-e6 in Treating Moderate to Severe Acne N-chlorin e6 triglumine, acne removal surgery - Acne, Photodynamic Therapy | Phase 2 | Unknown | Xiyuan Hospital of China Academy of Chinese Medical Sciences | 46 | 2024-02-01 | 2024-03-15 |
| The Effect of Photodynamic Therapy on Post-extraction Third Molar Experimental: antimicrobial photodynamic therapy (aPDT) after extraction of third molar - Photodynamic Therapy, Third Molar Extraction | Not applicable | Completed | Universita di Verona | 60 | 2023-11-03 | 2025-05-09 |
| Comparison of 5-ALA Photodynamic Therapy and CO2 Laser for Treating Persistent Low-Grade Cervical Lesions With High-Risk HPV Infection CO2 - HPV-Related Cervical Carcinoma, Low-Grade Squamous Intraepithelial Lesions | Not applicable | Recruiting | First Affiliated Hospital of Wenzhou Medical University | 40 | 2023-09-11 | 2025-05-13 |
| The Effect of Topical Imipramine on Pain and Effectiveness of Topical Photodynamic Therapy Imipramine, Vehicle - Imipramine, Photodynamic Therapy | Phase 1 | Recruiting | Wright State University | 24 | 2023-01-19 | 2026-08-20 |
| Photodynamic Therapy With Hydrogel Dressing for Chronic Wounds Photodynamic therapy, Hydrogel dressing - Photodynamic Therapy | Not applicable | Unknown | Army Medical University, China | 69 | 2023-01-01 | 2024-07-30 |
| Portable Measurement of Protoporphyrin IX in the Skin Portable Apple Smart Phone Protoporphyrin IX Spectrometer Camera - Photodynamic Therapy, Protoporphyrin IX | Completed | Dartmouth-Hitchcock Medical Center | 219 | 2022-12-01 | 2025-11-21 | |
| Clinical and Radiographic Evaluation of Photodynamic Therapy for Root Canal Treatment of Primary Molars photodynamic therapy, pulpectomy with metapex - Photodynamic Therapy | Not applicable | Unknown | Mansoura University | 60 | 2022-12-01 | 2023-04-20 |
| The Effect of Leukocyte and Platelet-rich Fibrin With Antimicrobial Photodynamic Therapy in Aggressive Periodontitis L-PRF with antimicrobial photodynamic therapy, antimicrobial photodynamic therapy without L-PRF - L-PRF, Photodynamic Therapy | Not applicable | Unknown | Kafrelsheikh University | 20 | 2021-11-22 | 2024-04-11 |
| Treatment of Intrabony Defects With Simvastatin and Antimicrobial Photodynamic Therapy SMV and antimicrobial photodynamic therapy, SMV application - Simvastatin, Photodynamic Therapy | Not applicable | Unknown | Kafrelsheikh University | 20 | 2021-10-16 | 2024-04-11 |
| Photodynamic Therapy and Microvesicles Photodynamic Therapy, 4% Imipramine, Base Cream - Photodynamic Therapy, Microvesicle Particle | Early Phase 1 | Withdrawn | Wright State University | 2021-03-29 | 2022-09-13 | |
| Photodynamic Therapy in Patients With Gingivitis scaling and root planing (SRP) + PDT placebo, scaling and root planing (SRP) + PDT - Gingivitis, Orthodontic Appliance Complication | Not applicable | Completed | University of Nove de Julho | 20 | 2020-11-09 | 2023-10-11 |
| Treatment of Herpes Labialis by Photodynamic Therapy photodynamic therapy herpes labialis - Photodynamic Therapy, Herpes Simplex, Labial | Not applicable | Completed | University of Nove de Julho | 24 | 2020-01-01 | 2023-11-21 |
| Photodynamic Therapy-Induced Immune Modulation: Part III Celecoxib 200mg, Placebo - Actinic Keratosis, Photodynamic Therapy | Phase 1 | Terminated | Wright State University | 12 | 2019-04-01 | 2024-12-19 |
| Low Concentration ALA-PDT in Treatment of Skin Ulcer ALA-PDT, red light - Skin Ulcer, Photodynamic Therapy | Not applicable | Unknown | Sichuan Provincial People's Hospital | 28 | 2019-01-01 | 2020-12-30 |
| Optimizing Uptake of Methylaminolevulinat With Fractional Ablative Laser Technique Laser+Methylaminolevulinat - Photodynamic Therapy, Ablative Fractional Laser | Phase 4 | Completed | Bispebjerg Hospital | 12 | 2012-05-01 | 2015-07-28 |
| Treatment of Basal Cell Carcinomas With Methyl Aminolevulinate and Daylight Daylight mediated photodynamic therapy - Photodynamic Therapy, Basal Cell Carcinomas | Phase 2 | Unknown | Bispebjerg Hospital | 2011-03-01 | 2011-05-06 |
Keratosis, Actinic (4) · Acne Vulgaris (1) · Aggressive Periodontitis (1) · Carcinoma, Basal Cell (1) · Central Serous Chorioretinopathy (1) · Esophageal Neoplasms (1) · Gingivitis (1) · Herpes Labialis (1) · Herpes Simplex (1) · Papillomavirus Infections (1) · Periodontal Diseases (1) · Skin Ulcer (1) · Squamous Intraepithelial Lesions (1)
Skin Diseases (7) · Skin and Connective Tissue Diseases (7) · Neoplasms (6) · Keratosis (4) · Mouth Diseases (4) · Precancerous Conditions (4) · Stomatognathic Diseases (4) · Infections (3) · DNA Virus Infections (2) · Periodontal Diseases (2) · Virus Diseases (2) · Acneiform Eruptions (1) · Carcinoma (1) · Communicable Diseases (1) · Digestive System Diseases (1)
Photochemotherapy (4) · Imipramine (3) · 1-phenyl-3,3-dimethyltriazene (1) · Bandages, Hydrocolloid (1) · Celecoxib (1) · Metapex (1) · Pulpectomy (1) · Red Light (1) · Root Planing (1) · Tooth Exfoliation (1)
Wright State University (3) · Bispebjerg Hospital (2) · Kafrelsheikh University (2) · University of Nove de Julho (2) · Army Medical University, China (1) · Beijing Hospital (1) · Dartmouth-Hitchcock Medical Center (1) · First Affiliated Hospital of Wenzhou Medical University (1) · Mansoura University (1) · Sichuan Provincial People's Hospital (1) · Sun Yat-sen University (1) · Universita di Verona (1) · VA Office of Research and Development (1) · Xiyuan Hospital of China Academy of Chinese Medical Sciences (1)
China (5) · United States (5) · Egypt (3) · Brazil (2) · Denmark (2) · Italy (1)
Dalia R Issa, PhD (2) · Jeffrey B Travers, MD, PhD (2) · Anna Carolina R Horliana, Phd (1) · Craig Rohan, MD (1) · Huiyan Chi, doctor (1) · Jeffrey Travers, MD (1) · Merete Haedersdal, MD PhD (1) · Michael S Chapman, MD, MBA (1) · Rui Yin, MD, PhD (1)
PMID 19382840, PMID 19524035, PMID 23618600, PMID 25770054, PMID 26687616, PMID 29851256, PMID 29868164, PMID 29926944, PMID 30048762, PMID 30122563, PMID 30399455, PMID 30989655, PMID 32195950, PMID 32243363, PMID 32835877, PMID 33538338, PMID 35288319, PMID 40485092