21 completed, 7 recruiting, 4 unknown, 2 terminated. 9 Not applicable, 9 Phase 3, 6 Phase 2, 6 Phase 4, 4 Phase 1.
Follow Imipramine: new trials by email Literature Review of Imipramine trials Research Report on Imipramine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma, GHoST Trial Chemotherapy, Computed Tomography, Internet-Based Intervention - Glioma, Recurrent Glioma | Not applicable | Recruiting | Mayo Clinic | 202 | 2025-09-12 | 2026-08-10 |
| The Effect of Topical Imipramine on Photodynamic Therapy-Mediated Immunosuppression on Forearms or Face on US Veterans Imipramine, Control Vehicle - Actinic Keratosis, Imipramine | Phase 2 | Recruiting | VA Office of Research and Development | 48 | 2025-04-01 | 2025-12-22 |
| Neuroregulators for the Treatment of Diseases Associated With Esophageal-brain-gut Axis Communication Abnormalities. Takepron, Zoloft 50Mg Tablet, Imipramine Pill - Gut-Brain Disorders, GERD Without Erosive Esophagitis | Not applicable | Recruiting | Hualien Tzu Chi General Hospital | 610 | 2024-04-02 | 2026-09-08 |
| New Treatment for Nocturnal Enuresis in Children Sulbutiamine, Imipramine - Nocturnal Enuresis in Children | Not applicable | Unknown | Sohag University | 450 | 2024-03-01 | 2024-07-12 |
| Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Patients With Rosacea Imipramine, Amitriptyline, Vehicle - Rosacea | Phase 2 | Recruiting | Wright State University | 48 | 2024-02-27 | 2026-02-18 |
| Efficacy of Hydroxyzine for Patients With Panic Disorder Hydroxyzine, Escitalopram Oxalate - Panic Disorder | Phase 4 | Not yet recruiting | Sultan Qaboos University | 80 | 2023-12-30 | 2023-02-21 |
| Therapeutic Efficacy in Women With Stress Urinary Incontinence duloxetine, Imipramine - Women With Stress Urinary Incontinence | Phase 3 | Unknown | Far Eastern Memorial Hospital | 90 | 2023-04-18 | 2023-05-19 |
| The Effect of Topical Imipramine on Pain and Effectiveness of Topical Photodynamic Therapy Imipramine, Vehicle - Imipramine, Photodynamic Therapy | Phase 1 | Recruiting | Wright State University | 24 | 2023-01-19 | 2026-08-20 |
| Comparative Responses to 15 Different Antidepressants in Major Depressive Disorder Antidepressant - Major Depressive Disorder | Completed | Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital | 73336 | 2022-10-01 | 2023-08-18 | |
| Investigator-Initiated Study of Imipramine Hydrochloride and Lomustine in Recurrent Glioblastoma Lomustine, Imipramine Hydrochloride - Glioblastoma | Phase 2 | Recruiting | The University of Texas Health Science Center at San Antonio | 25 | 2022-05-25 | 2025-08-27 |
| Bio-significance of LPC16:0 in Fibromyalgia Pregabalin 150mg, imipramine 25mg - Fibromyalgia, Primary, Pain | Recruiting | Kaohsiung Medical University Chung-Ho Memorial Hospital | 245 | 2021-06-01 | 2025-06-26 | |
| Photodynamic Therapy and Microvesicles Photodynamic Therapy, 4% Imipramine, Base Cream - Photodynamic Therapy, Microvesicle Particle | Early Phase 1 | Withdrawn | Wright State University | 2021-03-29 | 2022-09-13 | |
| Comparisons of the Impact of Duloxetine Versus Imipramine on Therapeutic Efficacy, Psychological Distress, Sexual Function, Urethral and Bladder Wall Structure and Blood Flow in Women With Stress Urinary Incontinence: a Randomized Controlled Study Duloxetine, Imipramine - Stress Urinary Incontinence | Phase 3 | Withdrawn | Far Eastern Memorial Hospital | 2020-05-31 | 2022-08-17 | |
| Imipramine on ER+ve and Triple Negative Breast Cancer Imipramine - Breast Cancer | Early Phase 1 | Completed | The University of Texas Health Science Center at San Antonio | 17 | 2019-07-05 | 2023-06-28 |
| Does Single Dose Imipramine Affect the Opening Pressure of the Urethral and Anal Sphincter? Placebo Oral Tablet, Imipramine Hydrochloride 25 MG - Urinary Incontinence, Stress, Fecal Incontinence | Phase 1 | Completed | Jonatan Kornholt | 16 | 2017-05-16 | 2021-02-12 |
| Pharmacovigilance in Gerontopsychiatric Patients Phenobarbital, Phenytoin, Carbamazepine - Dementia, Depression | Phase 3 | Terminated | Hannover Medical School | 407 | 2015-01-01 | 2018-02-28 |
| Interpersonal Psychotherapy for Treatment Resistant Depression IPT+ antidepressant drugs, fluoxetine, sertraline - Treatment Resistant Depression | Not applicable | Unknown | Hospital de Clinicas de Porto Alegre | 74 | 2013-04-01 | 2013-07-11 |
| Efficacy of Imipramine for Treatment of Patients With Esophageal Hypersensitivity/ Functional Heartburn imipramine - Gastroesophageal Reflux Disease | Phase 3 | Completed | Mahidol University | 83 | 2012-12-01 | 2014-08-18 |
| Linking Altered Central Pain Processing and Genetic Polymorphism to Drug Efficacy in Chronic Low Back Pain (Predictio) Oxycodone 15mg, Clobazam, Imipramine - Low Back Pain | Phase 3 | Completed | Insel Gruppe AG, University Hospital Bern | 150 | 2010-07-01 | 2016-04-06 |
| Medication Effects on Periurethral Sensation,Urethral Sphincter Activity and Pressure Flow Parameters Pseudoephedrine, Tamsulosin, Imipramine - Urethral Sphincter Activity | Not applicable | Completed | University of Alabama at Birmingham | 56 | 2010-04-01 | 2012-06-08 |
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Depression (9) · Depressive Disorder, Major (6) · Arrhythmias, Cardiac (3) · Cardiovascular Diseases (3) · Dysthymic Disorder (3) · Heart Diseases (3) · Anxiety Disorders (2) · Gastroesophageal Reflux (2) · Glioblastoma (2) · Keratosis, Actinic (2) · Panic Disorder (2) · Urinary Incontinence, Stress (2) · Ventricular Fibrillation (2) · Acquired Immunodeficiency Syndrome (1) · Breast Neoplasms (1)
New York State Psychiatric Institute (3) · Wright State University (3) · Far Eastern Memorial Hospital (2) · The University of Texas Health Science Center at San Antonio (2) · Birte Glenthoj (1) · Chinese University of Hong Kong (1) · GEIGY Pharmaceuticals (1) · Hannover Medical School (1) · Hospital Universitari de Bellvitge (1) · Hospital de Clinicas de Porto Alegre (1) · Hualien Tzu Chi General Hospital (1) · Insel Gruppe AG, University Hospital Bern (1) · Jonatan Kornholt (1) · Kaohsiung Medical University Chung-Ho Memorial Hospital (1) · Mahidol University (1)
United States (15) · Denmark (4) · Taiwan (4) · Brazil (1) · Egypt (1) · Germany (1) · Hong Kong (1) · Poland (1) · Spain (1) · Switzerland (1) · Thailand (1)
Jonathan W. Stewart, MD. (2) · Allan Barker (1) · Andreas Siegenthaler, Dr Med (1) · Andrzej Zieba, Prof. (1) · Birte Glenthoj, MD, DMSc. (1) · Craig Pratt (1) · Craig Rohan, MD (1) · David Richardson (1) · Ellen Frank, PhD (1) · Frances A (1) · Gaetano Morelli, M.D. (1) · Gerard Bruder, PhD (1) · H. Greene (1) · Helge Frieling, Prof., MD (1)
PMID 16215338, PMID 16616268, PMID 18061147, PMID 18654615, PMID 19380256, PMID 26376691, PMID 26799332, PMID 28850362, PMID 30361080, PMID 36918228, PMID 39167201
2009 (1), R01HL031472 (1), R01HL034071 (1), R10MH045963 (1), R10MH045964 (1), R10MH045965 (1), R10MH045966 (1)