9 completed, 5 not yet recruiting, 4 recruiting, 3 unknown. 18 Not applicable, 2 Phase 2, 1 Early Phase 1, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 18 | Completed 8, Not yet recruiting 4, Recruiting 3, Unknown 3 |
| Phase 2 | 2 | Completed 1, Recruiting 1 |
| Early Phase 1 | 1 | Not yet recruiting 1 |
| Phase 1 | 1 | Recruiting 1 |
| Phase 3 | 1 | Completed 1 |
Follow Photobiomodulation: new trials by email Literature Review of Photobiomodulation trials Research Report on Photobiomodulation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluating How Red-light Therapy Applied to the Head Affects Symptoms, Daily Life, and Brain Activity in People With Dementia With Lewy Bodies LUCIOLE CAP, LUCIOLE CAP (sham version) - Photobiomodulation, Dementia With Lewy Bodies | Not applicable | Recruiting | University Hospital, Strasbourg, France | 40 | 2026-09-16 | 2026-10-27 |
| Nd:YAG Laser Photobiomodulation for Neurosensory Recovery Following Bimaxillary Orthognathic Surgery Nd:YAG laser photobiomodulation, Sham laser - Infraorbital Nerve Injury, Inferior Alveolar Nerve Injury | Not applicable | Not yet recruiting | National University Hospital, Singapore | 36 | 2026-09-01 | 2026-09-24 |
| The Use of Photobiomodulation in the Treatment of Spasticity After Stroke. Photobiomodulation Therapy, Placebo PBM, Standard Multidisciplinary Rehabilitation Program for Spasticity - Stroke, Spasticity | Phase 1 / Phase 2 | Recruiting | University of Nove de Julho | 42 | 2026-08-28 | 2026-09-01 |
| Photobiomodulation Effects on Fatigue and Muscle Damage Induced by NMES Active Photobiomodulation, Placebo Photobiomodulation, NMES-evoked fatigue protocol - Photobiomodulation, Fatigue | Not applicable | Recruiting | Federal University of Rio Grande do Sul | 36 | 2026-06-01 | 2026-08-25 |
| Effectiveness of Photobiomodulation for Myofascial Pain in Temporomandibular Disorders Photobiomodulation Therapy, Therapeutic Exercises, Sham Photobiomodulation Therapy - Photobiomodulation, Temporomandibular Disorder (TMD) | Not applicable | Not yet recruiting | Federal University of Rio Grande do Sul | 140 | 2026-03-10 | 2026-03-10 |
| Effects and Feasibility of Photobiomodulation at 830nm Nanometers in the Treatment of Diabetic Ulcers Low Level Laser Therapy - Diabete Type 2, Diabetic Foot Ulcer | Not applicable | Not yet recruiting | Federal University of Piaui | 136 | 2026-01-10 | 2025-07-10 |
| Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva Low-level laser therapy - Wound Healing and Prevention, Oral Inflammation | Not applicable | Recruiting | Medical University of South Carolina | 39 | 2025-11-05 | 2025-11-12 |
| LED Therapy for Third Molar Surgery photobiomodulation, Antibiotic - Molar, Third, Photobiomodulation | Early Phase 1 | Not yet recruiting | Huashan Hospital | 50 | 2024-10-14 | 2024-10-15 |
| Efficacy of Photobiomodulation in the Treatment and Relief of Pain in Recurrent Aphthous Stomatitis Gemini laser, Placebo - Photobiomodulation, Stomatitis, Aphthous | Not applicable | Unknown | Federal University of Rio Grande do Sul | 34 | 2024-07-01 | 2024-05-16 |
| Effect of Photobiomodulation to Reduce Post-operative Pain After Endodontic Surgery Ibuprofen, Photobiomodulation simulation, Photobiomodulation - Photobiomodulation, Endodontic Disease | Not applicable | Completed | University of Nove de Julho | 34 | 2024-06-30 | 2026-07-29 |
| Effects of Photobiomodulation on Insomnia in the Elderly: Clinical Trials of Phototherapy Devices Bright light, Near-infrared light, Bright light+ near-infrared light - Photobiomodulation | Not applicable | Completed | China Medical University Hospital | 60 | 2024-04-26 | 2025-12-02 |
| Preventive Effect of Photobiomodulation in the Postoperative Period of Extractions of Retained Lower Third Molars Photobiomodulation, Placebo Corticosteroid, Simulation Photobiomodulation - Molar, Third, Photobiomodulation | Not applicable | Completed | University of Nove de Julho | 30 | 2023-11-20 | 2026-07-29 |
| Therapeutic Photobiomodulation and Tretament of Spasticity Photobiomodulation, Institution's Standard Physiotherapy, Photobiomodulation Placebo - Muscle Spasticity, Cerebral Palsy | Phase 2 / Phase 3 | Completed | University of Nove de Julho | 12 | 2023-08-15 | 2026-05-01 |
| Transcranial Photobiomodulation as a Therapy for Patients With Parkinson's Disease: Relationship Between Pain and Brain Functional Connectivity (FBM) Photobiomodulation - Parkinson Disease, Pain | Not applicable | Unknown | University of Sao Paulo | 82 | 2023-06-16 | 2023-07-25 |
| Conservative Therapies in the Treatment of Temporomandibular Disorders Occlusal Splint, Laser Therapy, Acupuncture Laser Therapy - Temporomandibular Joint Disorders, Temporomandibular Joint Pain | Not applicable | Completed | Universidade Federal de Alfenas | 160 | 2023-03-01 | 2026-05-26 |
| Photobiomodulation for Dry Age Related Macula Degeneration Valeda machine - Photobiomodulation, Age-Related Macular Degeneration | Not applicable | Not yet recruiting | Oslo University Hospital | 121 | 2022-12-01 | 2022-10-12 |
| Evaluation of Tooth Sensitivity After Scaling and Root Planing Treated With Photobiomodulation Photobiomodulation, simulation of Photobiomodulation - Photobiomodulation, Dental Hypersensitivity | Not applicable | Completed | University of Nove de Julho | 112 | 2022-11-01 | 2024-11-26 |
| Influence of PBM on Anaerobic Capacity Under Normoxia and Hypoxia Photobiomodulation therapy - Low Level Laser Therapy, Photobiomodulation | Not applicable | Unknown | University of Sao Paulo | 7 | 2021-08-31 | 2022-10-27 |
| Influence of Power and Wavelength on Photobiomodulation Therapy for Muscle Performance in Healthy Subjects Photobiomodulation, Sham - Low Level Laser Therapy, Photobiomodulation | Not applicable | Completed | University of Sao Paulo | 42 | 2021-05-01 | 2022-10-21 |
| Effects of Led Photobiomodulation Therapy LLLT RED - Photobiomodulation | Not applicable | Completed | Indústria Brasileira Equipamentos Médicos - IBRAMED | 10 | 2020-08-08 | 2021-08-19 |
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Pain (3) · Inflammation (2) · Muscle Spasticity (2) · Temporomandibular Joint Disorders (2) · Agnosia (1) · Cerebral Palsy (1) · Dental Pulp Diseases (1) · Diabetes Mellitus, Type 2 (1) · Diabetic Foot (1) · Edema (1) · Facial Pain (1) · Fatigue (1) · Hypoxia (1) · Lewy Body Disease (1) · Macular Degeneration (1)
Pathological Conditions, Signs and Symptoms (9) · Signs and Symptoms (9) · Neurologic Manifestations (7) · Nervous System Diseases (6) · Stomatognathic Diseases (5) · Brain Diseases (4) · Central Nervous System Diseases (4) · Muscular Diseases (4) · Musculoskeletal Diseases (4) · Basal Ganglia Diseases (2) · Cardiovascular Diseases (2) · Craniomandibular Disorders (2) · Jaw Diseases (2) · Joint Diseases (2) · Mandibular Diseases (2)
Low-Level Light Therapy (13) · Adrenal Cortex Hormones (1) · Anti-Bacterial Agents (1) · Exercise Therapy (1) · Ibuprofen (1) · Laser Therapy (1) · Occlusal Splints (1) · salicylhydroxamic acid (1)
University of Nove de Julho (5) · Federal University of Rio Grande do Sul (3) · University of Sao Paulo (3) · China Medical University Hospital (1) · Federal University of Piaui (1) · Huashan Hospital (1) · Indústria Brasileira Equipamentos Médicos - IBRAMED (1) · Medical University of South Carolina (1) · National University Hospital, Singapore (1) · Oslo University Hospital (1) · Pia Lopez Jornet (1) · Universidade Federal de Alfenas (1) · University Hospital, Strasbourg, France (1)
Brazil (10) · China (1) · France (1) · Spain (1) · Taiwan (1) · United States (1) · Uruguay (1)
Anna CR Horliana, PhD (1) · Ariane Zoll (1) · Carlos E Girasol, PhD (1) · Carlos E Girasol, Student (1) · Daniel Almeida, PhD (1) · Manoela Domingues Martins, DDS, MSc, PhD (1) · Manoela Martins, PhD (1) · Marco A Vaz, PhD (1) · Pia Lopez Jornet (1) · Pinar Emecen-Huja (1) · Rebeca B Cecatto (1)