378 completed, 60 unknown, 16 recruiting, 11 withdrawn. 330 Phase 1, 46 Not applicable, 30 Phase 4, 21 Phase 2, 9 Phase 3.
Follow Pharmacokinetics: new trials by email Literature Review of Pharmacokinetics trials Research Report on Pharmacokinetics
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A First-in-Human SAD and MAD Study in Healthy Participants to Evaluate Oral YR011 Tablet Kv1.3 potassium channel blocker (PA032, investigational oral small-molecule drug), Placebo - Safety, Tolerability | Phase 1 | Not yet recruiting | Hangzhou Yirui Pharmaceutical Technology Co., Ltd | 64 | 2027-04-01 | 2026-07-30 |
| Tenofovir Exposures in Advanced Kidney Disease Study Plasma sampling for tenofovir and emtricitabine, Descovy - Tenofovir, Tenofovir Alafenamide Fumarate | Not yet recruiting | King's College Hospital NHS Trust | 50 | 2026-11-01 | 2026-09-10 | |
| Effects of Trigonelline Monohydrate on NAD+ Metabolism, Pharmacokinetics, Safety, and Tolerability in Healthy Adults Nicotinamide Mononucleotide (NMN), Placebo, Trigonelline Monohydrate - NAD+ Metabolism, Pharmacokinetics | Phase 1 | Not yet recruiting | dsm-firmenich Switzerland AG | 60 | 2026-10-01 | 2026-10-19 |
| A Randomized, Double-Blind, Positive-Controlled, Parallel Pharmacokinetic Phase I Clinical Study of Cetuximab Injection Versus Erbitux in Healthy Male Subjects HC034S, Erbitux (Cetuximab) - Cetuximab, Bioequivalence | Phase 1 | Recruiting | HC Biopharma Inc. | 92 | 2026-09-05 | 2026-09-10 |
| A Randomized, Multicenter, Open-label, Active-controlled Phase Ib Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of Multiple Intravaginal Doses of GenSci142 in Patients With Bacterial Vaginosis (BV) GenSci142 capsule, clindamycin phosphate vaginal cream - Randomized, Open-label | Phase 1 | Recruiting | Changchun GeneScience Pharmaceutical Co., Ltd. | 42 | 2026-08-15 | 2026-10-15 |
| To Evaluate the Safety, Tolerability, Pharmacokinetics and the Effect of Food on the Hemay5259 Sustained-release Tablets in Healthy Subjects. Hemay5259 group 1, placebo group 1, Hemay5259 group 2 - Pharmacokinetics | Phase 1 | Not yet recruiting | Hemay Pharmaceutical PTY. LTD. | 32 | 2026-07-01 | 2026-07-15 |
| Pharmacokinetics of Kava and Kratom Alone and in Combination Kava and Kratom Herbal Supplement, Kava Herbal Supplement, Kratom Herbal Supplement - Herb-Herb Interaction, Pharmacokinetics | Not applicable | Active not recruiting | Botanic Tonics, LLC | 18 | 2026-05-04 | 2026-09-03 |
| Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar/Interchangeable Rapid-Acting Insulin Aspart (I004) and NovoLog® After Single-Dose Subcutaneous Administration to Healthy Volunteers I004, NovoLog - Pharmacokinetics, Pharmacodynamics | Phase 2 / Phase 3 | Completed | Amphastar Pharmaceuticals, Inc. | 62 | 2026-04-06 | 2026-07-22 |
| MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic Function Midomafetamine HCl - Pharmacokinetics, Hepatic Impairment | Phase 1 | Not yet recruiting | Resilient Pharmaceuticals | 16 | 2026-03-29 | 2024-10-30 |
| Comparing the Extent to Which Two Evolocumab Drug Products Are Made Available in the Body After a Single Subcutaneous Dose Evolocumab Drug Substance A, Evolocumab Drug Substance B - Healthy Participants, Pharmacokinetics | Phase 1 | Completed | Amgen | 405 | 2026-01-16 | 2026-08-17 |
| Study in Healthy Subjects to Investigate the Relative Bioavailability and Safety of Pasireotide After Single Subcutaneous Dose Administration Using a Reusable ServoPen With Cartridge as Compared to Administration Using a Syringe Drawn From an Ampule Pasireotide cartridge with reusable ServoPen, Pasireotide ampule with syringe - Pharmacokinetics, Safety | Phase 1 | Completed | RECORDATI GROUP | 40 | 2025-12-01 | 2026-02-04 |
| Study of BB-025, Alone and After BB-031, in Healthy Volunteers BB-025, BB-031 - Pharmacodynamics, Pharmacokinetics | Phase 1 | Completed | Basking Biosciences, Inc. | 72 | 2025-11-05 | 2026-04-06 |
| Food Effect on PK of DW-1021 (Pelubiprofen 45 mg / Tramadol 45.9 mg) in Healthy Adults DW-1021 - Healthy Volunteers, Pharmacokinetics | Phase 1 | Recruiting | Haiphong University of Medicine and Pharmacy | 14 | 2025-09-20 | 2025-08-28 |
| A Study to Evaluate the Safety and Pharmacokinetics of AG2304 Compared to Coadministration of AG23041 and AG23042 AG2304, AG23041 and AG23042 - Pharmacokinetics | Phase 1 | Not yet recruiting | Ahn-Gook Pharmaceuticals Co.,Ltd | 70 | 2025-08-01 | 2025-04-08 |
| A Study Evaluating How Moderate Liver Impairment Affects the Absorption, Distribution, Metabolism, and Elimination of Sevabertinib After a Single Oral Dose Sevabertinib - Hepatic Insufficiency, Liver Diseases | Phase 1 | Completed | Bayer | 18 | 2025-07-24 | 2026-02-10 |
| Safety and Pharmacokinetics of Cannabidiol in Healthy Volunteers Cannabidiol - Pharmacokinetics | Phase 1 | Completed | Tiamat Australia Pty Ltd | 20 | 2025-07-14 | 2026-02-04 |
| High Potency Cannabis: Acute and Protracted Effects Placebo Comparator: Placebo, Low dose THC, High dose THC - Abuse Cannabis, Pain | Phase 1 | Recruiting | University of California, Los Angeles | 30 | 2025-07-03 | 2026-09-04 |
| Single Ascending Dose and Multiple Ascending Dose Study of AVR-48 AVR-48, Placebo - Safety Issues, Tolerability | Phase 1 | Not yet recruiting | AyuVis Research, Inc. | 48 | 2025-06-01 | 2025-04-06 |
| A Study to Evaluate the the Bioequivalence of Two Different Pimicotinib Capsules in Healthy Subjects pimicotinib capsules - Pharmacokinetics | Phase 1 | Completed | Abbisko Therapeutics Co, Ltd | 38 | 2025-05-13 | 2025-08-17 |
| A Study to Investigate Lithium Brain/Plasma Pharmacokinetics and Safety of an AL001 Oral Capsule Compared to a Marketed Immediate-release Lithium Carbonate Capsule in Healthy Adult Subjects AL001, Lithium Carbonate Capsule - Pharmacokinetics, Neurology | Phase 1 | Completed | Alzamend Neuro, Inc. | 15 | 2025-05-09 | 2026-07-29 |
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PMID 21480191, PMID 16531428, PMID 16640454, PMID 19095679, PMID 19237886, PMID 21142293, PMID 22194591, PMID 22839761, PMID 23153962, PMID 24080664, PMID 25712752, PMID 25808018, PMID 26414659, PMID 26603304, PMID 26614499, PMID 34866168, PMID 3588249, PMID 1444289, PMID 1482149, PMID 16304153, PMID 17135183, PMID 17846133, PMID 18235022, PMID 18774510, PMID 18788687, PMID 18798078, PMID 19114462, PMID 19398460, PMID 19692373, PMID 19774117, PMID 20051587, PMID 20128565, PMID 20151342, PMID 20215446, PMID 20561826, PMID 21730935, PMID 21788467, PMID 21809372, PMID 21810837, PMID 21819507, PMID 2186240, PMID 21862409, PMID 21914174, PMID 22030215, PMID 22168538, PMID 22178175, PMID 22512898, PMID 22832034, PMID 22913907, PMID 22940371
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