116 completed, 19 terminated, 7 unknown, 4 active not recruiting. 93 Phase 1, 31 Phase 2, 14 Phase 3, 7 Early Phase 1, 7 Not applicable.
Follow Ketoconazole: new trials by email Literature Review of Ketoconazole trials Research Report on Ketoconazole
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ketoconazole Effects on the Daily Cortisol Rhythm in Mild Autonomous Cortisol Secretion Ketoconazole - Mild Autonomous Cortisol Secretion | Phase 1 | Recruiting | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 36 | 2026-07-27 | 2026-08-31 |
| Comparison of the Efficacy of Topical Luliconazole 2% Cream vs Topical Ketoconazole 1% Cream in the Treatment of Pityriasis Versicolor. Luliconazole Cream 1%, Topical ketoconazole 2% cream - Pityriasis Versicolor | Phase 4 | Not yet recruiting | PAEC General Hospital, Islamabad | 86 | 2026-02-01 | 2026-01-12 |
| Mycological Efficacy and Safety of Ketoconazole 2% Shampoo With a Seven-Day Versus Three-Day Treatment Duration in Pityriasis Versicolor Ketoconazole 2% Shampoo, Placebo Shampoo - Pityriasis Versicolor | Phase 4 | Not yet recruiting | Fakultas Kedokteran Universitas Indonesia | 76 | 2026-02-01 | 2026-03-13 |
| Cytochrome P450 Inhibition to Decrease Dosage of Dasatinib for Chronic Myelogenous Leukemia Dasatinib Pill, Ketoconazole Pill - Chronic Myeloid Leukemia, Chronic Phase | Phase 2 | Unknown | Hospital Universitario Dr. Jose E. Gonzalez | 15 | 2024-11-01 | 2022-12-06 |
| Azoles Targeting Recurrent High Grade Gliomas Ketoconazole (KCZ), Posaconazole (PCZ) - Brain Tumor, Recurrent, Cancer, Advanced | Early Phase 1 | Not yet recruiting | University Health Network, Toronto | 30 | 2024-06-01 | 2024-03-08 |
| Ketoconazole Contributes to Cryptorchidism Outcome Via Modulating Macrophage Trem2 Ketoconazole, Luteinizing Hormone - Cryptorchidism | Not applicable | Unknown | Affiliated Hospital of Nantong University | 10 | 2024-02-03 | 2024-08-19 |
| Administration of Repurposed Ketoconazole in Glioma Patients Ketoconazole - Diffuse Glioma, Diffuse Glioma, Grade I | Early Phase 1 | Active not recruiting | Universitas Padjadjaran | 80 | 2023-02-28 | 2026-05-14 |
| Neuro-pharmacological Properties of Repurposed Ketoconazole in Glioblastomas Ketoconazole - Glioblastoma, Glioblastoma Multiforme | Early Phase 1 | Terminated | Milton S. Hershey Medical Center | 1 | 2022-05-11 | 2026-01-07 |
| Hormonal Mechanisms of Sleep Restriction - Axis Study in Older Men and Postmenopausal Women Ketoconazole Pill (also known as nizoral), Ganirelix, Dexamethasone Pill - Sleep Restriction | Early Phase 1 | Active not recruiting | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 5 | 2020-02-09 | 2025-09-11 |
| Bioavailability of Levoketoconazole and Ketoconazole Tablets Levoketoconazole, Ketoconazole - Healthy | Phase 1 | Completed | Cortendo AB | 34 | 2019-12-16 | 2020-01-31 |
| Effectiveness Study of Ketoconazole and Betamethasone to Treat Fungal Infection and Dermatophytosis Candicort®, Nizoral®, Baycuten N® - Tinea | Phase 3 | Completed | Ache Laboratorios Farmaceuticos S.A. | 125 | 2019-06-11 | 2021-09-20 |
| ITT-5 Mechanisms of Spermatogenesis in Man Testosterone 1% Gel, Acyline, Dutasteride - Gonadotropin Deficiency | Phase 2 | Withdrawn | University of Washington | 2019-06-01 | 2019-12-18 | |
| To Evaluate the Efficacy and Safety of Shampoo TD03 and TD07 in Scalp Diseases TD03, TD07, Ketoconazole 2% Shampoo - Scalp Dermatitis | Phase 3 | Unknown | Sao Thai Duong Joint Stock Company | 366 | 2019-05-22 | 2022-10-26 |
| Ketoconazole Before Surgery in Treating Patients With Recurrent Glioma or Breast Cancer Brain Metastases Best Practice, Ketoconazole - Anatomic Stage IV Breast Cancer AJCC v8, Astrocytoma | Early Phase 1 | Terminated | Wake Forest University Health Sciences | 15 | 2019-03-13 | 2026-07-31 |
| Omiganan Twice a Day (BID) in Patients With Facial Seborrheic Dermatitis Omiganan, Ketoconazole, Placebo - Seborrheic Dermatitis | Phase 2 | Unknown | Maruho Co., Ltd. | 36 | 2018-10-22 | 2019-05-01 |
| Ketoconazole in Treating Participants With Ongoing EGFR Inhibitor-Induced Rash Ketoconazole, Laboratory Biomarker Analysis, Placebo Administration - Malignant Neoplasm | Early Phase 1 | Completed | Mayo Clinic | 58 | 2018-09-25 | 2026-09-21 |
| Ketoconazole Gel Versus Terconazole Cream for Vaginal Candidiasis Ketoconazole, Terconazole - Vaginal Candidiasis | Phase 3 | Unknown | Assiut University | 69 | 2018-04-01 | 2018-03-22 |
| Non-inferiority Trial of Dapaconazole Versus Ketoconazole Dapaconazole, Ketoconazole - Tinea Pedis | Phase 3 | Completed | Biolab Sanus Farmaceutica | 360 | 2017-11-01 | 2020-07-27 |
| Hormonal Mechanisms of Sleep Restriction - Axis Study Ketoconazole Pill, Ganirelix, Dexamethasone - Sleep Restriction | Phase 1 | Active not recruiting | Peter y. Liu | 80 | 2017-05-08 | 2025-09-11 |
| Oral Calcitriol With Ketoconazole in CRPC Calcitriol, Ketoconazole, Hydrocortisone - Castration-resistant Prostate Cancer | Phase 2 | Terminated | Donald Trump, MD | 1 | 2017-01-06 | 2021-02-08 |
Showing 20 of 155. Sign in to see all of them.
Prostatic Neoplasms (23) · Neoplasms (12) · Dermatitis, Seborrheic (4) · Lymphoma (4) · Tinea Pedis (4) · Hypogonadism (3) · Neuroblastoma (3) · Pulmonary Disease, Chronic Obstructive (3) · Tinea Versicolor (3) · Alzheimer Disease (2) · Asthma (2) · Brain Neoplasms (2) · Candidiasis (2) · Diabetes Mellitus, Type 2 (2) · Glioblastoma (2)
GlaxoSmithKline (14) · Boehringer Ingelheim (6) · Pfizer (6) · AstraZeneca (5) · Abbott (4) · Hoffmann-La Roche (4) · Janssen Research & Development, LLC (4) · Celgene (3) · Eli Lilly and Company (3) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (3) · M.D. Anderson Cancer Center (3) · National Cancer Institute (NCI) (3) · Roswell Park Cancer Institute (3) · South Plains Oncology Consortium (3) · Astellas Pharma Inc (2)
United States (100) · United Kingdom (9) · Australia (5) · Germany (5) · South Korea (5) · Brazil (4) · Canada (4) · Belgium (3) · Netherlands (3) · France (2) · Singapore (2) · Spain (2) · China (1) · Indonesia (1) · Mexico (1)
Donald L. Trump, MD (2) · Gilberto De Nucci, PhD (2) · Gregory P. Swanson, MD (2) · Peter Liu, MD, PhD (2) · Randall E. Millikan, MD, PhD (2) · Robert J Amato, DO (2) · Aibing M Guo, M.D. (1)
PMID 12560440, PMID 12610188, PMID 14747052, PMID 15020604, PMID 16258090, PMID 17404083, PMID 18073301, PMID 18270253, PMID 18401254, PMID 18445673, PMID 18451235, PMID 19029421, PMID 19734776, PMID 20430905, PMID 20881067, PMID 21480191, PMID 21642470, PMID 22174351, PMID 22393898, PMID 22463890, PMID 22510871, PMID 22534255, PMID 22606232, PMID 22845044, PMID 22895351, PMID 22932804, PMID 23150682, PMID 23303450, PMID 23377341, PMID 23533230, PMID 23715032, PMID 23750331, PMID 23754575, PMID 23851165, PMID 24009246, PMID 24298851, PMID 24323034, PMID 24417786, PMID 24655871, PMID 24824900, PMID 24918945, PMID 25047497, PMID 25100135, PMID 25211297, PMID 25514427, PMID 25667107, PMID 25807408, PMID 26381275, PMID 26872892, PMID 27171844
P30CA016672 (3), 2009 (2), 2008 (1), N01HR56165 (1), N01HR56166 (1), N01HR56167 (1), N01HR56168 (1), N01HR56169 (1), N01HR56170 (1), N01HR56171 (1), N01HR56172 (1), N01HR56173 (1), N01HR56174 (1), N01HR56175 (1), N01HR56176 (1)