45 completed, 19 unknown, 8 terminated, 8 withdrawn. 26 Not applicable, 14 Phase 4, 12 Phase 2, 10 Phase 3, 7 Phase 1.
Follow Peripheral Arterial Occlusive Disease 1: new trials by email Literature Review of Peripheral Arterial Occlusive Disease 1 trials Research Report on Peripheral Arterial Occlusive Disease 1
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety of Antithrombotic Heparin Proteoglycan Mimetic APAC in Peripheral Arterial Occlusive Disease and Chronic Limb-threatening Ischemia APAC - dose level 0.50 mg/kg,, Unfractionated heparin (UFH), APAC dose level 1: 0.25 mg/kg, - Peripheral Arterial Occlusive Disease, Chronic Limb-Threatening Ischemia | Phase 2 | Recruiting | Aplagon Oy | 42 | 2026-01-29 | 2026-04-09 |
| Prevalence of Obstructive Sleep Apnea in Patients With Peripheral Arterial Occlusive Disease Peripheral Artery Disease | Recruiting | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer | 295 | 2025-11-05 | 2026-07-07 | |
| Patients With Type 2 Diabetes Diabetes Mellitus Type 2 | Recruiting | National Taiwan University Hospital | 2000 | 2025-10-09 | 2026-09-15 | |
| Wearable Devices Assist in the Detection, Screening, and Management of Major Diseases in Middle-aged and Elderly Populations Smartwatch + GP, GP only - Coronary Stenosis, Cerebral Arterial Diseases | Not applicable | Not yet recruiting | Tongji Hospital | 800 | 2025-06-01 | 2025-05-20 |
| VITUS Post-Market Registry Percutaneous Transluminal Angioplasty with a paclitaxel drug-coated balloon - Peripheral Arterial Disease, Peripheral Arterial Occlusive Disease | Active not recruiting | OrbusNeich | 283 | 2025-05-22 | 2026-08-13 | |
| Xeltis Peripheral Artery Disease (XPAD) Bypass Conduit Early Feasibility Study Xeltis Peripheral Artery Disease (XPAD) Bypass Conduit - Peripheral Artery Occlusive Disease | Not applicable | Active not recruiting | Xeltis | 6 | 2025-05-02 | 2026-10-06 |
| Medium-term Results of Lower Limb Arterial Bypass Graft dysfunction will be assessed through clinical examination and imaging follow-up to detect occlusion, pseudoaneurysm, aneurysm rupture, infection, or major amputation of the treated limb. - Peripheral Arterial Occlusive Disease, Critical Limb Ischemia | Completed | Hospices Civils de Lyon | 57 | 2025-01-01 | 2025-07-30 | |
| Impact of Nrf2 Activation on Macrovascular, Microvascular & Leg Function & Walking Capacity in Peripheral Artery Disease Vumerity, Placebo - Peripheral Artery Disease, Peripheral Vascular Diseases | Early Phase 1 | Recruiting | University of Nebraska | 20 | 2024-11-14 | 2026-06-24 |
| Leg Exercise Assistive Paddling (LEAP) Therapy for Peripheral Artery Disease LEAP therapy, no LEAP therapy - Peripheral Arterial Disease, Peripheral Vascular Disease | Not applicable | Withdrawn | University of Nebraska | 2024-08-16 | 2026-08-21 | |
| Safety, Tolerability, and Biodistribution of [89Zr]Zr-DFO-APAC in Subjects With PAOD/CLI and Healthy Volunteers (Acronyms: 89Zr = Zirconium-89, DFO = Desferrioxamine, APAC = AntiPlatelet AntiCoagulant, PET/CT = Positron Emission Tomography/Computed Tomography) [89Zr]Zr-DFO-APAC, PET/CT scan - Peripheral Arterial Occlusive Disease, Critical Limb Ischemia | Early Phase 1 | Unknown | Aplagon Oy | 10 | 2024-02-01 | 2025-01-30 |
| RESPONSE-2-PAD to Reduce Sedentary Time in Peripheral Arterial Disease Patients RESPONSE-2-PAD - Peripheral Arterial Disease, Sedentary Behavior | Not applicable | Unknown | National Institute for Prevention and Cardiovascular Health, Ireland | 50 | 2023-09-29 | 2024-04-09 |
| The SIR-POBA Bypass Trial Balloon Angioplasty - Peripheral Arterial Occlusive Disease, Bypass Complication | Not applicable | Withdrawn | Paracelsus Medical University | 2023-09-20 | 2025-06-29 | |
| FRAMED Infrainguinal Venous Bypass Versus Conventional Autologous Bypass Trial FRAMED Infrainguinal Venous Bypass, Conventional Autologous Bypass - Peripheral Arterial Occlusive Disease, Femoropopliteal Artery Occlusion | Not applicable | Recruiting | Paracelsus Medical University | 110 | 2023-09-11 | 2023-11-21 |
| Efficacy and Safety of the Regulatory Polypeptides in Patients With Peripheral Atherosclerosis. Polypeptides, Femoral-popliteal bypass grafting with a synthetic graft above the knee, Routine conservative treatment - Peripheral Arterial Occlusive Disease | Not applicable | Unknown | Ryazan State Medical University | 120 | 2023-04-01 | 2023-07-06 |
| The EasyFlype/EasyHiFlype Post Market Clinical Follow-up Study. Easy Flype/EasyHiFlype - Peripheral Artery Disease, Peripheral Arterial Occlusive Disease | Completed | CID S.p.A. | 52 | 2023-03-18 | 2026-10-22 | |
| Prospective Study of the SoundBite™ Crossing System in Complex Peripheral CTOs SoundBite™ Crossing System - Peripheral - Peripheral Arterial Occlusive Disease, Chronic Total Occlusion of Artery of the Extremities | Not applicable | Withdrawn | SoundBite Medical Solutions, Inc. | 2022-12-30 | 2023-09-14 | |
| Risk Factors for Adverse Outcomes of Endovascular Revascularization in Lower Extremity Arteriosclerosis Occlusion endovascular revascularization - Peripheral Arterial Occlusive Disease | Unknown | First Affiliated Hospital Xi'an Jiaotong University | 500 | 2022-10-20 | 2024-03-06 | |
| Regional Anesthesia for Percutaneous Transluminal Angioplasty Near Infrared Spectroscopy (NIRS) - Peripheral Artery Occlusive Disease, Percutaneous Transluminal Angioplasty | Completed | Gazi University | 70 | 2022-09-24 | 2023-12-20 | |
| Fespixon Cream for the Treatment of Chronic Diabetic Foot Ulcers (TEXAS 1A, 2A) in Dialysis Patients Fespixon Cream - Chronic Diabetic Foot Ulcer | Phase 4 | Completed | Cathay General Hospital | 5 | 2021-12-01 | 2024-04-03 |
| Peripheral Artery Occlusive Disease (PAOD) in Women Hospitalized for Type 1 Myocardial Infarction in Intensive Cardiology Care PAOD - Peripheral Arterial Occlusive Disease | Unknown | University Hospital, Strasbourg, France | 50 | 2021-08-15 | 2021-12-08 |
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Peripheral Arterial Disease (22) · Peripheral Vascular Diseases (13) · Chronic Limb-Threatening Ischemia (12) · Intermittent Claudication (9) · Arterial Occlusive Diseases (7) · Atherosclerosis (7) · Diabetes Mellitus (3) · Motor Activity (3) · Vascular Diseases (3) · Arteriosclerosis (2) · Disease (2) · Myocardial Infarction (2) · Acute Coronary Syndrome (1) · Alzheimer Disease (1)
Cardiovascular Diseases (45) · Vascular Diseases (43) · Arterial Occlusive Diseases (32) · Arteriosclerosis (32) · Atherosclerosis (26) · Pathological Conditions, Signs and Symptoms (26) · Peripheral Vascular Diseases (21) · Pathologic Processes (16) · Ischemia (14) · Chronic Disease (12) · Disease Attributes (12) · Peripheral Arterial Disease (11) · Signs and Symptoms (11) · Endocrine System Diseases (5) · Behavior (4)
Angioplasty (5) · Angioplasty, Balloon (3) · Stents (3) · Alprostadil (2) · Iopamidol (2) · Sildenafil Citrate (2) · Sodium Chloride (2) · iodixanol (2) · Angiography (1) · Arginine (1) · Clonidine (1) · Combined Modality Therapy (1) · Dexmedetomidine (1) · Heparin (1) · Injections (1)
Abbott Medical Devices (5) · Sanofi (5) · B. Braun Melsungen AG (3) · Cordis US Corp. (3) · Flanders Medical Research Program (3) · Aplagon Oy (2) · Bracco Diagnostics, Inc (2) · Hull University Teaching Hospitals NHS Trust (2) · Imperial College London (2) · Johann Wolfgang Goethe University Hospital (2) · Kantonsspital Baselland Bruderholz (2) · Maquet Cardiovascular (2) · Paracelsus Medical University (2) · University Hospital, Angers (2) · University of Nebraska (2)
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George Adams, MD (2) · Klaus Amendt, MD (2) · Manish Mehta, MD, MPH (2) · Marc Bosiers, MD (2) · Patrick Peeters, MD (2) · Stephanie Rassam, MD (2) · Tony S. Das, MD (2) · Afshin Assadian, MD (1) · Afshin Assadian, Prim PD Dr (1) · Alan Lumsden, MD (1) · Alun H Davies, BA BMChB MA (1) · Alun H Davies, MA FRCS DM (1)
PMID 21716303, PMID 31912491, PMID 18990592, PMID 19762206, PMID 20354489, PMID 20471779, PMID 21205939, PMID 21586692, PMID 22021102, PMID 22277685, PMID 23792625, PMID 23842831, PMID 25498193, PMID 27763685, PMID 28189475, PMID 28225505, PMID 29242062, PMID 30092443, PMID 30361959, PMID 30722718, PMID 31152977, PMID 32103970, PMID 32618486, PMID 32753875, PMID 32769505, PMID 32780436, PMID 33016805, PMID 33094679, PMID 33581715, PMID 33866936, PMID 33932282, PMID 34057276, PMID 35503774, PMID 37066103, PMID 41159585, PMID 41994540
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